-
1
-
-
0034733888
-
Investigation of the melanocyte stimulating hormones on food intake. Lack of evidence to support a role for the melanocortin-3- receptor
-
Abbott, C.R., Rossi, M., Kim, M., AlAhmed, S.H., Taylor, G.M., Ghatei, M.A., Smith, D.M., Bloom, S.R., 2000. Investigation of the melanocyte stimulating hormones on food intake. Lack Of evidence to support a role for the melanocortin-3- receptor. Brain Res. 869, 203-210.
-
(2000)
Brain Res.
, vol.869
, pp. 203-210
-
-
Abbott, C.R.1
Rossi, M.2
Kim, M.3
AlAhmed, S.H.4
Taylor, G.M.5
Ghatei, M.A.6
Smith, D.M.7
Bloom, S.R.8
-
2
-
-
0033567543
-
The anatomy of an endogenous antagonist: Relationship between agouti-related protein and proopiomelanocortin in brain
-
Bagnol, D., Lu, X.Y., Kaelin, C.B., Day, H.E., Ollmann, M., Gantz, I., Akil, H., Barsh, G.S., Watson, S.J., 1999. The anatomy of an endogenous antagonist: relationship between agouti-related protein and proopiomelanocortin in brain. J. Neurosci. 19, RC26.
-
(1999)
J. Neurosci.
, vol.19
-
-
Bagnol, D.1
Lu, X.Y.2
Kaelin, C.B.3
Day, H.E.4
Ollmann, M.5
Gantz, I.6
Akil, H.7
Barsh, G.S.8
Watson, S.J.9
-
3
-
-
0043068115
-
Structure-activity relationships of novel cyclic alpha-MSH/beta-MSH hybrid analogues that lead to potent and selective ligands for the human melanocortin MC3 receptor and human MC5R
-
Balse-Srinivasan, P., Grieco, P., Cai, M., Trivedi, D., Hruby, V.J., 2003. Structure-activity relationships of novel cyclic alpha-MSH/beta-MSH hybrid analogues that lead to potent and selective ligands for the human melanocortin MC3 receptor and human MC5R. J. Med. Chem. 46, 3728-3733.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 3728-3733
-
-
Balse-Srinivasan, P.1
Grieco, P.2
Cai, M.3
Trivedi, D.4
Hruby, V.J.5
-
4
-
-
70449411697
-
The role of melanocortin neuronal pathways in circadian biology: A new homeostatic output involving melanocortin-3 receptors?
-
Begriche, K., Sutton, G.M., Fang, J., Butler, A.A., 2009. The role of melanocortin neuronal pathways in circadian biology: a new homeostatic output involving melanocortin-3 receptors? Obes. Rev. 10 (Suppl. 2), 14-24.
-
(2009)
Obes. Rev.
, vol.10
, Issue.SUPPL. 2
, pp. 14-24
-
-
Begriche, K.1
Sutton, G.M.2
Fang, J.3
Butler, A.A.4
-
5
-
-
0036046234
-
A +2138InsCAGACC polymorphism of the melanocortin receptor 3 gene is associated in human with fat level and partitioning in interaction with body corpulence
-
Boucher, N., Lanouette, C.M., Larose, M., Perusse, L., Bouchard, C., Chagnon, Y.C., 2002. A +2138InsCAGACC polymorphism of the melanocortin receptor 3 gene is associated in human with fat level and partitioning in interaction with body corpulence. Mol. Med. 8, 158-165.
-
(2002)
Mol. Med.
, vol.8
, pp. 158-165
-
-
Boucher, N.1
Lanouette, C.M.2
Larose, M.3
Perusse, L.4
Bouchard, C.5
Chagnon, Y.C.6
-
6
-
-
33845972656
-
The natural inverse agonist agouti-related protein induces arrestin-mediated endocytosis of melanocortin-3 and -4 receptors
-
Breit, A., Wolff, K., Kalwa, H., Jarry, H., Buch, T., Gudermann, T., 2006. The natural inverse agonist agouti-related protein induces arrestin-mediated endocytosis of melanocortin-3 and -4 receptors. J. Biol. Chem. 281, 37447-37456.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 37447-37456
-
-
Breit, A.1
Wolff, K.2
Kalwa, H.3
Jarry, H.4
Buch, T.5
Gudermann, T.6
-
7
-
-
0034456398
-
A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse
-
DOI 10.1210/en.141.9.3518
-
Butler, A.A., Kesterson, R.A., Khong, K., Cullen, M.J., Pelleymounter, M.A., Dekoning, J., Baetscher, M., Cone, R.D., 2000. A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse. Endocrinology 141, 3518-3521. (Pubitemid 32269044)
-
(2000)
Endocrinology
, vol.141
, Issue.9
, pp. 3518-3521
-
-
Butler, A.A.1
Kesterson, R.A.2
Khong, K.3
Cullen, M.J.4
Pelleymounter, M.A.5
Dekoning, J.6
Baetscher, M.7
Cone, R.D.8
-
8
-
-
15544377449
-
Novel 3D pharmacophore of alpha-MSH/gamma-MSH hybrids leads to selective human MC1R and melanocortin MC3 receptor analogues
-
Cai, M., Mayorov, A.V., Cabello, C., Stankova, M., Trivedi, D., Hruby, V.J., 2005. Novel 3D pharmacophore of alpha-MSH/gamma-MSH hybrids leads to selective human MC1R and melanocortin MC3 receptor analogues. J. Med. Chem. 48, 1839-1848.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 1839-1848
-
-
Cai, M.1
Mayorov, A.V.2
Cabello, C.3
Stankova, M.4
Trivedi, D.5
Hruby, V.J.6
-
9
-
-
0021883901
-
Sympathetic nervous system mediation of acute cardiovascular actions of gamma 2-melanocyte-stimulating hormone
-
Callahan, M.F., Kirby, R.F., Wolff, D.W., Strandhoy, J.W., Lymangrover, J.R., Johnson, A.K., Gruber, K.A., 1985. Sympathetic nervous system mediation of acute cardiovascular actions of gamma 2-melanocyte-stimulating hormone. Hypertension 7, I145-I150.
-
(1985)
Hypertension
, vol.7
-
-
Callahan, M.F.1
Kirby, R.F.2
Wolff, D.W.3
Strandhoy, J.W.4
Lymangrover, J.R.5
Johnson, A.K.6
Gruber, K.A.7
-
10
-
-
61849161252
-
Association of functionally significant melanocortin-4 but not melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study
-
Calton, M.A., Ersoy, B.A., Zhang, S., Kane, J.P., Malloy, M.J., Pullinger, C.R., Bromberg, Y., Pennacchio, L.A., Dent, R., McPherson, R., Ahituv, N., Vaisse, C., 2009. Association of functionally significant melanocortin-4 but not melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study. Hum. Mol. Genet. 18, 1140-1147.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 1140-1147
-
-
Calton, M.A.1
Ersoy, B.A.2
Zhang, S.3
Kane, J.P.4
Malloy, M.J.5
Pullinger, C.R.6
Bromberg, Y.7
Pennacchio, L.A.8
Dent, R.9
McPherson, R.10
Ahituv, N.11
Vaisse, C.12
-
11
-
-
33846698560
-
The melanocortin system in leukocyte biology
-
Catania, A., 2007. The melanocortin system in leukocyte biology. J. Leukoc. Biol. 81, 383-392.
-
(2007)
J. Leukoc. Biol.
, vol.81
, pp. 383-392
-
-
Catania, A.1
-
12
-
-
1542347163
-
Targeting melanocortin receptors as a novel strategy to control inflammation
-
Catania, A., Gatti, S., Colombo, G., Lipton, J.M., 2004. Targeting melanocortin receptors as a novel strategy to control inflammation. Pharmacol. Rev. 56, 1-29.
-
(2004)
Pharmacol. Rev.
, vol.56
, pp. 1-29
-
-
Catania, A.1
Gatti, S.2
Colombo, G.3
Lipton, J.M.4
-
13
-
-
33846796378
-
Melanocortin-3 receptor activates MAP kinase via PI3 kinase
-
Chai, B., Li, J.Y., Zhang, W., Ammori, J.B., Mulholland, M.W., 2007. Melanocortin-3 receptor activates MAP kinase via PI3 kinase. Regul. Pept. 139, 115-121.
-
(2007)
Regul. Pept.
, vol.139
, pp. 115-121
-
-
Chai, B.1
Li, J.Y.2
Zhang, W.3
Ammori, J.B.4
Mulholland, M.W.5
-
14
-
-
70149093650
-
Role of gamma melanocyte-stimulating hormone-renal melanocortin 3 receptor system in blood pressure regulation in salt-resistant and salt-sensitive rats
-
Chandramohan, G., Durham, N., Sinha, S., Norris, K., Vaziri, N.D., 2009. Role of gamma melanocyte-stimulating hormone-renal melanocortin 3 receptor system in blood pressure regulation in salt-resistant and salt-sensitive rats. Metabolism 58, 1424-1429.
-
(2009)
Metabolism
, vol.58
, pp. 1424-1429
-
-
Chandramohan, G.1
Durham, N.2
Sinha, S.3
Norris, K.4
Vaziri, N.D.5
-
15
-
-
0033818103
-
Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass
-
Chen, A.S., Marsh, D.J., Trumbauer, M.E., Frazier, E.G., Guan, X.M., Yu, H., Rosenblum, C.I., Vongs, A., Feng, Y., Cao, L., Metzger, J.M., Strack, A.M., Camacho, R.E., Mellin, T.N., Nunes, C.N., Min, W., Fisher, J., Gopal-Truter, S., MacIntyre, D.E., Chen, H.Y., Van der Ploeg, L.H., 2000. Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass. Nat. Genet. 26, 97-102.
-
(2000)
Nat. Genet.
, vol.26
, pp. 97-102
-
-
Chen, A.S.1
Marsh, D.J.2
Trumbauer, M.E.3
Frazier, E.G.4
Guan, X.M.5
Yu, H.6
Rosenblum, C.I.7
Vongs, A.8
Feng, Y.9
Cao, L.10
Metzger, J.M.11
Strack, A.M.12
Camacho, R.E.13
Mellin, T.N.14
Nunes, C.N.15
Min, W.16
Fisher, J.17
Gopal-Truter, S.18
MacIntyre, D.E.19
Chen, H.Y.20
Van Der Ploeg, L.H.21
more..
-
16
-
-
31544441358
-
Molecular characterization of human melanocortin-3 receptor ligand-receptor interaction
-
DOI 10.1021/bi0521792
-
Chen, M., Aprahamian, C.J., Celik, A., Georgeson, K.E., Garvey, W.T., Harmon, C.M., Yang, Y., 2006. Molecular characterization of human melanocortin-3 receptor ligand-receptor interaction. Biochemistry 45, 1128-1137. (Pubitemid 43167180)
-
(2006)
Biochemistry
, vol.45
, Issue.4
, pp. 1128-1137
-
-
Chen, M.1
Aprahamian, C.J.2
Celik, A.3
Georgeson, K.E.4
Garvey, W.T.5
Harmon, C.M.6
Yang, Y.7
-
17
-
-
20444497662
-
Role of leptin and melanocortin signaling in uremia-associated cachexia
-
Cheung, W., Yu, P.X., Little, B.M., Cone, R.D., Marks, D.L., Mak, R.H., 2005. Role of leptin and melanocortin signaling in uremia-associated cachexia. J. Clin. Invest. 115, 1659-1665.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1659-1665
-
-
Cheung, W.1
Yu, P.X.2
Little, B.M.3
Cone, R.D.4
Marks, D.L.5
Mak, R.H.6
-
18
-
-
0029848043
-
Distribution of cDNA for melanocortin receptor subtypes in human tissues
-
Chhajlani, V., 1996. Distribution of cDNA for melanocortin receptor subtypes in human tissues. Biochem. Mol. Biol. Int. 38, 73-80.
-
(1996)
Biochem. Mol. Biol. Int.
, vol.38
, pp. 73-80
-
-
Chhajlani, V.1
-
19
-
-
0027396787
-
Familial glucocorticoid deficiency associated with point mutation in the adrenocorticotropin receptor
-
DOI 10.1016/0140-6736(93)90208-X
-
Clark, A.J., McLoughlin, L., Grossman, A., 1993. Familial glucocorticoid deficiency associated with point mutation in the adrenocorticotropin receptor. Lancet 341, 461-462. (Pubitemid 23054520)
-
(1993)
Lancet
, vol.341
, Issue.8843
, pp. 461-462
-
-
Clark, A.J.L.1
McLoughlin, L.2
Grossman, A.3
-
20
-
-
0035942777
-
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
-
DOI 10.1038/35078085
-
Cowley, M.A., Smart, J.L., Rubinstein, M., Cerdan, M.G., Diano, S., Horvath, T.L., Cone, R.D., Low, M.J., 2001. Leptin activates anorexigenic proopiomelanocortin neurons through a neural network in the arcuate nucleus. Nature 411, 480-484. (Pubitemid 32494394)
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 480-484
-
-
Cowley, M.A.1
Smart, J.L.2
Rubinstein, M.3
Cerdan, M.G.4
Diano, S.5
Horvath, T.L.6
Cone, R.D.7
Low, M.J.8
-
21
-
-
0033637383
-
Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
-
Damiola, F., Le Minh, N., Preitner, N., Kornmann, B., Fleury-Olela, F., Schibler, U., 2000. Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes Dev. 14, 2950-2961.
-
(2000)
Genes Dev.
, vol.14
, pp. 2950-2961
-
-
Damiola, F.1
Le Minh, N.2
Preitner, N.3
Kornmann, B.4
Fleury-Olela, F.5
Schibler, U.6
-
22
-
-
36348946386
-
Obesity-induced inflammation in white adipose tissue is attenuated by loss of melanocortin-3 receptor signaling
-
DOI 10.1210/en.2007-0699
-
Ellacott, K.L., Murphy, J.G., Marks, D.L., Cone, R.D., 2007. Obesity-induced inflammation in white adipose tissue is attenuated by loss of melanocortin-3 receptor signaling. Endocrinology 148, 6186-6194. (Pubitemid 350146148)
-
(2007)
Endocrinology
, vol.148
, Issue.12
, pp. 6186-6194
-
-
Ellacott, K.L.J.1
Murphy, J.G.2
Marks, D.L.3
Cone, R.D.4
-
23
-
-
0343953074
-
Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency
-
Farooqi, I.S., Yeo, G.S., Keogh, J.M., Aminian, S., Jebb, S.A., Butler, G., Cheetham, T., O'Rahilly, S., 2000. Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency. J. Clin. Invest. 106, 271-279.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 271-279
-
-
Farooqi, I.S.1
Yeo, G.S.2
Keogh, J.M.3
Aminian, S.4
Jebb, S.A.5
Butler, G.6
Cheetham, T.7
O'Rahilly, S.8
-
24
-
-
24144443764
-
Co-occurrence of two partially inactivating polymorphisms of MC3R is associated with pediatric-onset obesity
-
DOI 10.2337/diabetes.54.9.2663
-
Feng, N., Young, S.F., Aguilera, G., Puricelli, E., Adler-Wailes, D.C., Sebring, N.G., Yanovski, J.A., 2005. Co-occurrence of two partially inactivating polymorphisms of melanocortin MC3 receptor is associated with pediatric-onset obesity. Diabetes 54, 2663-2667. (Pubitemid 41233588)
-
(2005)
Diabetes
, vol.54
, Issue.9
, pp. 2663-2667
-
-
Feng, N.1
Young, S.F.2
Aguillera, G.3
Puricelli, E.4
Adler-Wailes, D.C.5
Sebring, N.G.6
Yanovski, J.A.7
-
25
-
-
78649864368
-
Light at night increases body mass by shifting the time of food intake
-
Fonken, L.K., Workman, J.L., Walton, J.C., Weil, Z.M., Morris, J.S., Haim, A., Nelson, R.J., 2010. Light at night increases body mass by shifting the time of food intake. Proc. Natl. Acad. Sci. USA. 107, 18664-18669.
-
(2010)
Proc. Natl. Acad. Sci. USA.
, vol.107
, pp. 18664-18669
-
-
Fonken, L.K.1
Workman, J.L.2
Walton, J.C.3
Weil, Z.M.4
Morris, J.S.5
Haim, A.6
Nelson, R.J.7
-
26
-
-
0027456619
-
Molecular cloning of a novel melanocortin receptor
-
Gantz, I., Konda, Y., Tashiro, T., Shimoto, Y., Miwa, H., Munzert, G., Watson, S.J., DelValle, J., Yamada, T., 1993. Molecular cloning of a novel melanocortin receptor. J. Biol. Chem. 268, 8246-8250.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 8246-8250
-
-
Gantz, I.1
Konda, Y.2
Tashiro, T.3
Shimoto, Y.4
Miwa, H.5
Munzert, G.6
Watson, S.J.7
DelValle, J.8
Yamada, T.9
-
27
-
-
0034888386
-
Arthritic diseases: Melanocortin type 3 receptor agonists as potential therapeutics
-
Getting, S.J., Perretti, M., 2001. Arthritic diseases: melanocortin type 3 receptor agonists as potential therapeutics. Curr. Opin. Investig. Drugs 2, 1064-1069.
-
(2001)
Curr. Opin. Investig. Drugs
, vol.2
, pp. 1064-1069
-
-
Getting, S.J.1
Perretti, M.2
-
28
-
-
0033397801
-
Agonism at melanocortin receptor type 3 on macrophages inhibits neutrophil influx
-
Getting, S.J., Flower, R.J., Perretti, M., 1999a. Agonism at melanocortin receptor type 3 on macrophages inhibits neutrophil influx. Inflamm. Res. 48 (Suppl. 2), S140-S141.
-
(1999)
Inflamm. Res.
, vol.48
, Issue.SUPPL. 2
-
-
Getting, S.J.1
Flower, R.J.2
Perretti, M.3
-
29
-
-
0033564575
-
POMC gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation
-
Getting, S.J., Gibbs, L., Clark, A.J., Flower, R.J., Perretti, M., 1999b. Proopiomelanocortin gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation. J. Immunol. 162, 7446-7453. (Pubitemid 29277724)
-
(1999)
Journal of Immunology
, vol.162
, Issue.12
, pp. 7446-7453
-
-
Getting, S.J.1
Gibbs, L.2
Clark, A.J.L.3
Flower, R.J.4
Perretti, M.5
-
30
-
-
0347927272
-
Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: Studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor
-
Getting, S.J., Christian, H.C., Lam, C.W., Gavins, F.N., Flower, R.J., Schioth, H.B., Perretti, M., 2003. Redundancy of a functional melanocortin 1 receptor in the antiinflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor. J. Immunol. 170, 3323-3330. (Pubitemid 36302211)
-
(2003)
Journal of Immunology
, vol.170
, Issue.6
, pp. 3323-3330
-
-
Getting, S.J.1
Christian, H.C.2
Lam, C.W.3
Gavins, F.N.E.4
Flower, R.J.5
Schioth, H.B.6
Perretti, M.7
-
31
-
-
33845664425
-
Melanocortin 3 receptors control crystal-induced inflammation
-
DOI 10.1096/fj.06-6339com
-
Getting, S.J., Lam, C.W., Chen, A.S., Grieco, P., Perretti, M., 2006a. Melanocortin 3 receptors control crystal-induced inflammation. FASEB J. 20, 2234-2241. (Pubitemid 44953853)
-
(2006)
FASEB Journal
, vol.20
, Issue.13
, pp. 2234-2241
-
-
Getting, S.J.1
Lam, C.W.2
Chen, A.S.3
Grieco, P.4
Perretti, M.5
-
32
-
-
33751080408
-
8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse)
-
DOI 10.1124/mol.106.028878
-
Getting, S.J., Lam, C.W., Leoni, G., Gavins, F.N., Grieco, P., Perretti, M., 2006b. [D-Trp8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse). Mol. Pharmacol. 70, 1850-1855. (Pubitemid 44771900)
-
(2006)
Molecular Pharmacology
, vol.70
, Issue.6
, pp. 1850-1855
-
-
Getting, S.J.1
Lam, C.W.2
Leoni, G.3
Gavins, F.N.E.4
Grieco, P.5
Perretti, M.6
-
33
-
-
56949091561
-
A role for melanocortin MC3 receptor in modulating lung inflammation
-
Getting, S.J., Riffo-Vasquez, Y., Pitchford, S., Kaneva, M., Grieco, P., Page, C.P., Perretti, M., Spina, D., 2008. A role for melanocortin MC3 receptor in modulating lung inflammation. Pulm. Pharmacol. Ther. 21, 866-873.
-
(2008)
Pulm. Pharmacol. Ther.
, vol.21
, pp. 866-873
-
-
Getting, S.J.1
Riffo-Vasquez, Y.2
Pitchford, S.3
Kaneva, M.4
Grieco, P.5
Page, C.P.6
Perretti, M.7
Spina, D.8
-
34
-
-
0034727855
-
D-amino acid scan of gamma-melanocyte-stimulating hormone: Importance of Trp(8) on human MC3 receptor selectivity
-
Grieco, P., Balse, P.M., Weinberg, D., MacNeil, T., Hruby, V.J., 2000. D-amino acid scan of gamma-melanocyte-stimulating hormone: importance of Trp(8) on human MC3 receptor selectivity. J. Med. Chem. 43, 4998-5002.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 4998-5002
-
-
Grieco, P.1
Balse, P.M.2
Weinberg, D.3
MacNeil, T.4
Hruby, V.J.5
-
35
-
-
70149087276
-
Neuropeptide Y and gamma-melanocyte stimulating hormone (gamma-MSH) share a common pressor mechanism of action
-
Gruber, K.A., Fan, W., Akerberg, H., Larhammar, D., Chee, M.J., Colmers, W.F., Cone, R.D., 2009. Neuropeptide Y and gamma-melanocyte stimulating hormone (gamma-MSH) share a common pressor mechanism of action. Endocrine 35, 312-324.
-
(2009)
Endocrine
, vol.35
, pp. 312-324
-
-
Gruber, K.A.1
Fan, W.2
Akerberg, H.3
Larhammar, D.4
Chee, M.J.5
Colmers, W.F.6
Cone, R.D.7
-
36
-
-
33845354765
-
Cardiovascular and renal actions of melanocyte-stimulating hormone actions
-
Humphreys, M.H., 2007. Cardiovascular and renal actions of melanocyte-stimulating hormone actions. Curr. Opin. Nephrol. Hypertens. 16, 32-38.
-
(2007)
Curr. Opin. Nephrol. Hypertens
, vol.16
, pp. 32-38
-
-
Humphreys, M.H.1
-
37
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar, D., Lynch, C.A., Fairchild-Huntress, V., Dunmore, J.H., Fang, Q., Berkemeier, L.R., Gu, W., Kesterson, R.A., Boston, B.A., Cone, R.D., Smith, F.J., Campfield, L.A., Burn, P., Lee, F., 1997. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88, 131-141. (Pubitemid 27180337)
-
(1997)
Cell
, vol.88
, Issue.1
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
Dunmore, J.H.4
Fang, Q.5
Berkemeier, L.R.6
Gu, W.7
Kesterson, R.A.8
Boston, B.A.9
Cone, R.D.10
Smith, F.J.11
Campfield, L.A.12
Burn, P.13
Frank, L.14
-
38
-
-
17344381056
-
Differential effects of melanocortin peptides on ingestive behaviour in rats: Evidence against the i involvement of MC(3) receptor in the regulation of food intake
-
Kask, A., Rago, L., Wikberg, J.E., Schioth, H.B., 2000. Differential effects of melanocortin peptides on ingestive behaviour in rats: evidence against the i involvement of MC(3) receptor in the regulation of food intake. Neurosci. Lett. 283, 1-4.
-
(2000)
Neurosci. Lett.
, vol.283
, pp. 1-4
-
-
Kask, A.1
Rago, L.2
Wikberg, J.E.3
Schioth, H.B.4
-
39
-
-
0037030692
-
Novel cyclic templates of alpha-MSH give highly selective and potent antagonists/agonists for human melanocortin-3/4 receptors
-
Kavarana, M.J., Trivedi, D., Cai, M., Ying, J., Hammer, M., Cabello, C., Grieco, P., Han, G., Hruby, V.J., 2002. Novel cyclic templates of alpha-MSH give highly selective and potent antagonists/agonists for human melanocortin-3/4 receptors. J. Med. Chem. 45, 2644-2650.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 2644-2650
-
-
Kavarana, M.J.1
Trivedi, D.2
Cai, M.3
Ying, J.4
Hammer, M.5
Cabello, C.6
Grieco, P.7
Han, G.8
Hruby, V.J.9
-
40
-
-
0021260924
-
The distribution and projection of gamma-melanocyte stimulating hormone in the rat brain: An immunohistochemical analysis
-
DOI 10.1016/0006-8993(84)90539-0
-
Kawai, Y., Inagaki, S., Shiosaka, S., Shibasaki, T., Ling, N., Tohyama, M., Shiotani, Y., 1984. The distribution and projection of gamma-melanocyte- stimulating hormone in the rat brain: an immunohistochemical analysis. Brain Res. 297, 21-32. (Pubitemid 14131924)
-
(1984)
Brain Research
, vol.297
, Issue.1
, pp. 21-32
-
-
Kawai, Y.1
Inagaki, S.2
Shiosaka, S.3
-
41
-
-
0037200005
-
Identification of domains directing specificity of coupling to G-proteins for the melanocortin MC3 and MC4 receptors
-
Kim, C.S., Lee, S.H., Kim, R.Y., Kim, B.J., Li, S.Z., Lee, I.H., Lee, E.J., Lim, S.K., Bae, Y.S., Lee, W., Baik, J.H., 2002a. Identification of domains directing specificity of coupling to G-proteins for the melanocortin MC3 and MC4 receptors. J. Biol. Chem. 277, 31310-31317.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 31310-31317
-
-
Kim, C.S.1
Lee, S.H.2
Kim, R.Y.3
Kim, B.J.4
Li, S.Z.5
Lee, I.H.6
Lee, E.J.7
Lim, S.K.8
Bae, Y.S.9
Lee, W.10
Baik, J.H.11
-
42
-
-
0035996843
-
Sustained orexigenic effect of Agouti related protein may be not mediated by the melanocortin 4 receptor
-
DOI 10.1016/S0196-9781(02)00039-6, PII S0196978102000396
-
Kim, M.S., Rossi, M., Abbott, C.R., AlAhmed, S.H., Smith, D.M., Bloom, S.R., 2002b. Sustained orexigenic effect of agouti related protein may be not mediated by the melanocortin 4 receptor. Peptides 23, 1069-1076. (Pubitemid 34786295)
-
(2002)
Peptides
, vol.23
, Issue.6
, pp. 1069-1076
-
-
Kim, M.-S.1
Rossi, M.2
Abbott, C.R.3
AlAhmed, S.H.4
Smith, D.M.5
Bloom, S.R.6
-
43
-
-
0031884124
-
Different developmental patterns of melanocortin MC3 and MC4 receptor mRNA, predominance of Mc4 in fetal rat nervous system
-
DOI 10.1046/j.1365-2826.1998.00180.x
-
Kistler-Heer, V., Lauber, M.E., Lichtensteiger, W., 1998. Different developmental patterns of melanocortin MC3 and MC4 receptor mRNA: predominance of MC4 in fetal rat nervous system. J. Neuroendocrinol. 10, 133-146. (Pubitemid 28098528)
-
(1998)
Journal of Neuroendocrinology
, vol.10
, Issue.2
, pp. 133-146
-
-
Kistler-Heer, V.1
Lauber, M.E.2
Lichtensteiger, W.3
-
44
-
-
0028233234
-
Interaction of dual intracellular signaling pathways activated by the melanocortin-3 receptor
-
Konda, Y., Gantz, I., DelValle, J., Shimoto, Y., Miwa, H., Yamada, T., 1994. Interaction of dual intracellular signaling pathways activated by the melanocortin-3 receptor. J. Biol. Chem. 269, 13162-13166.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 13162-13166
-
-
Konda, Y.1
Gantz, I.2
DelValle, J.3
Shimoto, Y.4
Miwa, H.5
Yamada, T.6
-
45
-
-
0031012096
-
Identification of common polymorphisms in the coding sequence of the human MSH receptor (MCIR) with possible biological effects
-
Koppula, S.V., Robbins, L.S., Lu, D., Baack, E., White Jr., C.R., Swanson, N.A., Cone, R.D., 1997. Identification of common polymorphisms in the coding sequence of the human MSH receptor (MCIR) with possible biological effects. Hum. Mutat. 9, 30-36.
-
(1997)
Hum. Mutat.
, vol.9
, pp. 30-36
-
-
Koppula, S.V.1
Robbins, L.S.2
Lu, D.3
Baack, E.4
White Jr., C.R.5
Swanson, N.A.6
Cone, R.D.7
-
46
-
-
0031838353
-
Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by proopiomelanocortin mutations in humans
-
Krude, H., Biebermann, H., Luck, W., Horn, R., Brabant, G., Gruters, A., 1998. Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by proopiomelanocortin mutations in humans. Nat. Genet. 19, 155-157.
-
(1998)
Nat. Genet.
, vol.19
, pp. 155-157
-
-
Krude, H.1
Biebermann, H.2
Luck, W.3
Horn, R.4
Brabant, G.5
Gruters, A.6
-
47
-
-
0036963510
-
A novel melanocortin 3 receptor gene (melanocortin MC3 receptor) mutation associated with severe obesity
-
Lee, Y.S., Poh, L.K., Loke, K.Y., 2002. A novel melanocortin 3 receptor gene (melanocortin MC3 receptor) mutation associated with severe obesity. J. Clin. Endocrinol. Metab. 87, 1423-1426.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 1423-1426
-
-
Lee, Y.S.1
Poh, L.K.2
Loke, K.Y.3
-
48
-
-
84991847410
-
The role of melanocortin 3 receptor gene in childhood obesity
-
DOI 10.2337/db07-0225
-
Lee, Y.S., Poh, L.K., Kek, B.L., Loke, K.Y., 2007. The role of melanocortin 3 receptor gene in childhood obesity. Diabetes 56, 2622-2630. (Pubitemid 47523271)
-
(2007)
Diabetes
, vol.56
, Issue.10
, pp. 2622-2630
-
-
Yung, S.L.1
Poh, L.K.S.2
Kek, B.L.K.3
Kah, Y.L.4
-
49
-
-
39649094099
-
Effects of selective modulation of the central melanocortin-3-receptor on food intake and hypothalamic proopiomelanocortin expression
-
Lee, M., Kim, A., Conwell, I.M., Hruby, V., Mayorov, A., Cai, M., Wardlaw, S.L., 2008. Effects of selective modulation of the central melanocortin-3-receptor on food intake and hypothalamic proopiomelanocortin expression. Peptides 29, 440-447.
-
(2008)
Peptides
, vol.29
, pp. 440-447
-
-
Lee, M.1
Kim, A.2
Conwell, I.M.3
Hruby, V.4
Mayorov, A.5
Cai, M.6
Wardlaw, S.L.7
-
50
-
-
1842292786
-
Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q
-
Lembertas, A.V., Perusse, L., Chagnon, Y.C., Fisler, J.S., Warden, C.H., Purcell-Huynh, D.A., Dionne, F.T., Gagnon, J., Nadeau, A., Lusis, A.J., Bouchard, C., 1997. Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q. J. Clin. Invest. 100, 1240-1247.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 1240-1247
-
-
Lembertas, A.V.1
Perusse, L.2
Chagnon, Y.C.3
Fisler, J.S.4
Warden, C.H.5
Purcell-Huynh, D.A.6
Dionne, F.T.7
Gagnon, J.8
Nadeau, A.9
Lusis, A.J.10
Bouchard, C.11
-
51
-
-
57349184220
-
Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion
-
Leoni, G., Patel, H.B., Sampaio, A.L., Gavins, F.N., Murray, J.F., Grieco, P., Getting, S.J., Perretti, M., 2008. Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion. FASEB J. 22, 4228-4238.
-
(2008)
FASEB J.
, vol.22
, pp. 4228-4238
-
-
Leoni, G.1
Patel, H.B.2
Sampaio, A.L.3
Gavins, F.N.4
Murray, J.F.5
Grieco, P.6
Getting, S.J.7
Perretti, M.8
-
52
-
-
0033977437
-
Melanocortin 3 receptor (melanocortin MC3 receptor) gene variants in extremely obese women
-
Li, W.D., Joo, E.J., Furlong, E.B., Galvin, M., Abel, K., Bell, C.J., Price, R.A., 2000. Melanocortin 3 receptor (melanocortin MC3 receptor) gene variants in extremely obese women. Int. J. Obes. Relat. Metab. Disord. 24, 206-210.
-
(2000)
Int. J. Obes. Relat. Metab. Disord.
, vol.24
, pp. 206-210
-
-
Li, W.D.1
Joo, E.J.2
Furlong, E.B.3
Galvin, M.4
Abel, K.5
Bell, C.J.6
Price, R.A.7
-
53
-
-
0023157141
-
Prevention of reflex natiuresis after acute unilateral nephrectomy byneonatal administration of MSG
-
Lin, S.-Y., Wiedemann, E., Deschepper, C.F., Alper, R.H., Humpreys, M.H., 1987. Prevention of reflex natiuresis after acute unilateral nephrectomy byneonatal administration of MSG. Am. Physiol. Soc. F276-F282.
-
(1987)
Am. Physiol. Soc.
-
-
Lin, S.-Y.1
Wiedemann, E.2
Deschepper, C.F.3
Alper, R.H.4
Humpreys, M.H.5
-
54
-
-
0021894747
-
Gamma-2 MSH is natriuretic in the rat
-
Lymangrover, J.R., Buckalew, V.M., Harris, J., Klein, M.C., Gruber, K.A., 1985. Gamma-2 MSH is natriuretic in the rat. Endocrinology 116, 1227-1229. (Pubitemid 15136990)
-
(1985)
Endocrinology
, vol.116
, Issue.3
, pp. 1227-1229
-
-
Lymangrover, J.R.1
Buckalew, V.M.2
Harris, J.3
-
55
-
-
0035866377
-
Role of the central melanocortin system in cachexia
-
Marks, D.L., Ling, N., Cone, R.D., 2001. Role of the central melanocortin system in cachexia. Cancer Res. 61, 1432-1438. (Pubitemid 34292569)
-
(2001)
Cancer Research
, vol.61
, Issue.4
, pp. 1432-1438
-
-
Marks, D.L.1
Ling, N.2
Cone, R.D.3
-
56
-
-
31544453062
-
The regulation of food intake by selective stimulation of the type 3 melanocortin receptor (MC3R)
-
DOI 10.1016/j.peptides.2005.01.025, PII S0196978105004377, The Melanocortin Pathway 2005 Part II
-
Marks, D.L., Hruby, V., Brookhart, G., Cone, R.D., 2006. The regulation of food intake by selective stimulation of the type 3 melanocortin receptor (melanocortin MC3 receptor). Peptides 27, 259-264. (Pubitemid 43162897)
-
(2006)
Peptides
, vol.27
, Issue.2
, pp. 259-264
-
-
Marks, D.L.1
Hruby, V.2
Brookhart, G.3
Cone, R.D.4
-
57
-
-
0037387355
-
Differential role of melanocortin receptor subtypes in cachexia
-
DOI 10.1210/en.2002-221099
-
Marks, D.L., Butler, A.A., Turner, R., Brookhart, G., Cone, R.D., 2003. Differential role of melanocortin receptor subtypes in cachexia. Endocrinology 144, 1513-1523. (Pubitemid 36428494)
-
(2003)
Endocrinology
, vol.144
, Issue.4
, pp. 1513-1523
-
-
Marks, D.L.1
Butler, A.A.2
Turner, R.3
Brookhart, G.4
Cone, R.D.5
-
58
-
-
0029785717
-
Dietary sodium intake modulates pituitary proopiomelanocortin mRNA abundance
-
Mayan, H., Ling, K.T., Lee, E.Y., Wiedemann, E., Kalinyak, J.E., Humphreys, M.H., 1996. Dietary sodium intake modulates pituitary proopiomelanocortin mRNA abundance. Hypertension 28, 244-249. (Pubitemid 26322797)
-
(1996)
Hypertension
, vol.28
, Issue.2
, pp. 244-249
-
-
Mayan, H.1
Ling, K.-T.2
Lee, E.Y.3
Wiedemann, E.4
Kalinyak, J.E.5
Humphreys, M.H.6
-
59
-
-
42649092119
-
Sporadic mutations in melanocortin receptor 3 in morbid obese individuals
-
Mencarelli, M., Walker, G.E., Maestrini, S., Alberti, L., Verti, B., Brunani, A., Petroni, M.L., Tagliaferri, M., Liuzzi, A., Di Blasio, A.M., 2008. Sporadic mutations in melanocortin receptor 3 in morbid obese individuals. Eur. J. Hum. Genet. 16, 581-586.
-
(2008)
Eur. J. Hum. Genet.
, vol.16
, pp. 581-586
-
-
Mencarelli, M.1
Walker, G.E.2
Maestrini, S.3
Alberti, L.4
Verti, B.5
Brunani, A.6
Petroni, M.L.7
Tagliaferri, M.8
Liuzzi, A.9
Di Blasio, A.M.10
-
60
-
-
12144286408
-
Further evidence that melanocortins prevent myocardial reperfusion injury by activating melanocortin MC3 receptors
-
Mioni, C., Giuliani, D., Cainazzo, M.M., Leone, S., Bazzani, C., Grieco, P., Novellino, E., Tomasi, A., Bertolini, A., Guarini, S., 2003. Further evidence that melanocortins prevent myocardial reperfusion injury by activating melanocortin MC3 receptors. Eur. J. Pharmacol. 477, 227-234.
-
(2003)
Eur. J. Pharmacol.
, vol.477
, pp. 227-234
-
-
Mioni, C.1
Giuliani, D.2
Cainazzo, M.M.3
Leone, S.4
Bazzani, C.5
Grieco, P.6
Novellino, E.7
Tomasi, A.8
Bertolini, A.9
Guarini, S.10
-
61
-
-
33646500989
-
Expression of melanocortin MC3 and MC4 receptor mRNAs by neuropeptide Y neurons in the rat arcuate nucleus
-
Mounien, L., Bizet, P., Boutelet, I., Vaudry, H., Jegou, S., 2005. Expression of melanocortin MC3 and MC4 receptor mRNAs by neuropeptide Y neurons in the rat arcuate nucleus. Neuroendocrinology 82, 164-170.
-
(2005)
Neuroendocrinology
, vol.82
, pp. 164-170
-
-
Mounien, L.1
Bizet, P.2
Boutelet, I.3
Vaudry, H.4
Jegou, S.5
-
62
-
-
0028134706
-
Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain
-
Mountjoy, K.G., Mortrud, M.T., Low, M.J., Simerly, R.B., Cone, R.D., 1994. Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain. Mol. Endocrinol. 8, 1298-1308.
-
(1994)
Mol. Endocrinol.
, vol.8
, pp. 1298-1308
-
-
Mountjoy, K.G.1
Mortrud, M.T.2
Low, M.J.3
Simerly, R.B.4
Cone, R.D.5
-
63
-
-
0347137958
-
Melanocortin receptor-mediated mobilization of intracellular free calcium in HEK293 cells
-
Mountjoy, K.G., Kong, P.L., Taylor, J.A., Willard, D.H., Wilkison, W.O., 2001. Melanocortin receptor-mediated mobilization of intracellular free calcium in HEK293 cells. Physiol. Genomics 5, 11-19. (Pubitemid 33675198)
-
(2001)
Physiological Genomics
, vol.2001
, Issue.5
, pp. 11-19
-
-
Mountjoy, K.G.1
Kong, P.L.2
Taylor, J.A.3
Willard, D.H.4
Wilkison, W.O.5
-
64
-
-
0031978528
-
Prevention of reflex natriuresis after acute unilateral nephrectomy by melanocortin receptor antagonists
-
Ni, X.P., Kesterson, R.A., Sharma, S.D., Hruby, V.J., Cone, R.D., Wiedemann, E., Humphreys, M.H., 1998. Prevention of reflex natriuresis after acute unilateral nephrectomy by melanocortin receptor antagonists. Am. J. Physiol. 274, R931-R938.
-
(1998)
Am. J. Physiol.
, vol.274
-
-
Ni, X.P.1
Kesterson, R.A.2
Sharma, S.D.3
Hruby, V.J.4
Cone, R.D.5
Wiedemann, E.6
Humphreys, M.H.7
-
65
-
-
0037397005
-
Genetic disruption of gamma-melanocyte-stimulating hormone signaling leads to salt-sensitive hypertension in the mouse
-
Ni, X.P., Pearce, D., Butler, A.A., Cone, R.D., Humphreys, M.H., 2003. Genetic disruption of gamma-melanocyte-stimulating hormone signaling leads to salt-sensitive hypertension in the mouse. J. Clin. Invest. 111, 1251-1258.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 1251-1258
-
-
Ni, X.P.1
Pearce, D.2
Butler, A.A.3
Cone, R.D.4
Humphreys, M.H.5
-
66
-
-
33645421796
-
Modulation by dietary sodium intake of melanocortin 3 receptor mRNA and protein abundance in the rat kidney
-
Ni, X.P., Bhargava, A., Pearce, D., Humphreys, M.H., 2006a. Modulation by dietary sodium intake of melanocortin 3 receptor mRNA and protein abundance in the rat kidney. Am. J. Physiol. Regul. Integr. Comp. Physiol. 290, R560-R567.
-
(2006)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.290
-
-
Ni, X.P.1
Bhargava, A.2
Pearce, D.3
Humphreys, M.H.4
-
67
-
-
33750235776
-
Central receptors mediating the cardiovascular actions of melanocyte stimulating hormones
-
DOI 10.1097/01.hjh.0000249702.49854.fa, PII 0000487220061100000019
-
Ni, X.P., Butler, A.A., Cone, R.D., Humphreys, M.H., 2006b. Central receptors mediating the cardiovascular actions of melanocyte stimulating hormones. J. Hypertens. 24, 2239-2246. (Pubitemid 44611033)
-
(2006)
Journal of Hypertension
, vol.24
, Issue.11
, pp. 2239-2246
-
-
Ni, X.-P.1
Butler, A.A.2
Cone, R.D.3
Humphreys, M.H.4
-
68
-
-
0035130843
-
AgRP(83-132) acts as an inverse agonist on the human-melanocortin-4 receptor
-
Nijenhuis, W.A., Oosterom, J., Adan, R.A., 2001. AgRP(83-132) acts as an inverse agonist on the human-melanocortin-4 receptor. Mol. Endocrinol. 15, 164-171.
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 164-171
-
-
Nijenhuis, W.A.1
Oosterom, J.2
Adan, R.A.3
-
69
-
-
44649104515
-
Endosomal colocalization of melanocortin-3 receptor and beta-arrestins in CAD cells with altered modification of AKT/PKB
-
Nyan, D.C., Anbazhagan, R., Hughes-Darden, C.A., Wachira, S.J., 2008. Endosomal colocalization of melanocortin-3 receptor and beta-arrestins in CAD cells with altered modification of AKT/PKB. Neuropeptides 42, 355-366.
-
(2008)
Neuropeptides
, vol.42
, pp. 355-366
-
-
Nyan, D.C.1
Anbazhagan, R.2
Hughes-Darden, C.A.3
Wachira, S.J.4
-
70
-
-
77953810909
-
Melanocortin-3 receptor gene variants: Association with childhood obesity and eating behavior in Chilean families
-
Obregon, A.M., Amador, P., Valladares, M., Weisstaub, G., Burrows, R., Santos, J.L., 2010. Melanocortin-3 receptor gene variants: association with childhood obesity and eating behavior in Chilean families. Nutrition 26, 760-765.
-
(2010)
Nutrition
, vol.26
, pp. 760-765
-
-
Obregon, A.M.1
Amador, P.2
Valladares, M.3
Weisstaub, G.4
Burrows, R.5
Santos, J.L.6
-
71
-
-
0030764741
-
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
-
Ollmann, M.M., Wilson, B.D., Yang, Y.-K., Kerns, J.A., Chen, Y., Gantz, I., Barsh, G.S., 1997. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 278, 135-137.
-
(1997)
Science
, vol.278
, pp. 135-137
-
-
Ollmann, M.M.1
Wilson, B.D.2
Yang, Y.-K.3
Kerns, J.A.4
Chen, Y.5
Gantz, I.6
Barsh, G.S.7
-
72
-
-
3242795783
-
Inactivation and intracellular retention of the human I183N mutated melanocortin 3 receptor associated with obesity
-
Rached, M., Buronfosse, A., Begeot, M., Penhoat, A., 2004. Inactivation and intracellular retention of the human I183N mutated melanocortin 3 receptor associated with obesity. Biochim. Biophys. Acta 1689, 229-234.
-
(2004)
Biochim. Biophys. Acta
, vol.1689
, pp. 229-234
-
-
Rached, M.1
Buronfosse, A.2
Begeot, M.3
Penhoat, A.4
-
73
-
-
0027436690
-
Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system
-
Roselli-Rehfuss, L., Mountjoy, K.G., Robbins, L.S., Mortrud, M.T., Low, M.J., Tatro, J.B., Entwistle, M.L., Simerly, R.B., Cone, R.D., 1993. Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system. Proc. Natl Acad. Sci. USA 90, 8856-8860.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 8856-8860
-
-
Roselli-Rehfuss, L.1
Mountjoy, K.G.2
Robbins, L.S.3
Mortrud, M.T.4
Low, M.J.5
Tatro, J.B.6
Entwistle, M.L.7
Simerly, R.B.8
Cone, R.D.9
-
74
-
-
0027436690
-
Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system
-
Roselli-Rhefus, L., Mountjoy, K.G., Robbins, L.S., Mortrud, M.T., Low, M.J., Tatro, J.B., Entwistle, M.L., Simerly, R.B., Cone, R.C., 1993. Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system. Proc. Natl Acad. Sci. USA 90, 8856-8860.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 8856-8860
-
-
Roselli-Rhefus, L.1
Mountjoy, K.G.2
Robbins, L.S.3
Mortrud, M.T.4
Low, M.J.5
Tatro, J.B.6
Entwistle, M.L.7
Simerly, R.B.8
Cone, R.C.9
-
75
-
-
33947533651
-
Single nucleotide polymorphisms of the melanocortin-3 receptor gene are associated with substrate oxidation and first-phase insulin secretion in offspring of type 2 diabetic subjects
-
Rutanen, J., Pihlajamaki, J., Vanttinen, M., Salmenniemi, U., Ruotsalainen, E., Kuulasmaa, T., Kainulainen, S., Laakso, M., 2007. Single nucleotide polymorphisms of the melanocortin-3 receptor gene are associated with substrate oxidation and first-phase insulin secretion in offspring of type 2 diabetic subjects. J. Clin. Endocrinol. Metab. 92, 1112-1117.
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, pp. 1112-1117
-
-
Rutanen, J.1
Pihlajamaki, J.2
Vanttinen, M.3
Salmenniemi, U.4
Ruotsalainen, E.5
Kuulasmaa, T.6
Kainulainen, S.7
Laakso, M.8
-
76
-
-
70349785440
-
Energy intake andenergy expenditure among children with polymorphisms of themelanocortin-3 receptor
-
Savastano, D.M., Tanofsky-Kraff, M., Han, J.C., Ning, C., Sorg, R.A., Roza, C.A., Wolkoff, L.E., Anandalingam, K., Jefferson-George, K.S., Figueroa, R.E., Sanford, E.L., Brady, S., Kozlosky, M., Schoeller, D.A., Yanovski, J.A., 2009. Energy intake andenergy expenditure among children with polymorphisms of themelanocortin-3 receptor. Am. J. Clin. Nutr. 90, 912-920.
-
(2009)
Am. J. Clin. Nutr.
, vol.90
, pp. 912-920
-
-
Savastano, D.M.1
Tanofsky-Kraff, M.2
Han, J.C.3
Ning, C.4
Sorg, R.A.5
Roza, C.A.6
Wolkoff, L.E.7
Anandalingam, K.8
Jefferson-George, K.S.9
Figueroa, R.E.10
Sanford, E.L.11
Brady, S.12
Kozlosky, M.13
Schoeller, D.A.14
Yanovski, J.A.15
-
77
-
-
77953845379
-
Genetic and pharmacologic blockade of central melanocortin signaling attenuates cardiac cachexia in rodent models of heart failure
-
Scarlett, J.M., Bowe, D.D., Zhu, X., Batra, A.K., Grant, W.F., Marks, D.L., 2010. Genetic and pharmacologic blockade of central melanocortin signaling attenuates cardiac cachexia in rodent models of heart failure. J Endocrinol 206, 121-130.
-
(2010)
J Endocrinol
, vol.206
, pp. 121-130
-
-
Scarlett, J.M.1
Bowe, D.D.2
Zhu, X.3
Batra, A.K.4
Grant, W.F.5
Marks, D.L.6
-
78
-
-
0037255271
-
Melanocortin-3-receptor gene variants in morbid obesity
-
Schalin-Jantti, C., Valli-Jaakola, K., Oksanen, L., Martelin, E., Laitinen, K., Krusius, T., Mustajoki, P., Heikinheimo, M., Kontula, K., 2003. Melanocortin-3-receptor gene variants in morbid obesity. Int. J. Obes. Relat. Metab. Disord. 27, 70-74.
-
(2003)
Int. J. Obes. Relat. Metab. Disord.
, vol.27
, pp. 70-74
-
-
Schalin-Jantti, C.1
Valli-Jaakola, K.2
Oksanen, L.3
Martelin, E.4
Laitinen, K.5
Krusius, T.6
Mustajoki, P.7
Heikinheimo, M.8
Kontula, K.9
-
79
-
-
33645839593
-
Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or -4 receptors
-
Sutton, G.M., Trevaskis, J.L., Hulver, M.W., McMillan, R.P., Markward, N.J., Babin, M.J., Meyer, E.A., Butler, A.A., 2006. Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or -4 receptors. Endocrinology 147, 2183-2196.
-
(2006)
Endocrinology
, vol.147
, pp. 2183-2196
-
-
Sutton, G.M.1
Trevaskis, J.L.2
Hulver, M.W.3
McMillan, R.P.4
Markward, N.J.5
Babin, M.J.6
Meyer, E.A.7
Butler, A.A.8
-
80
-
-
58149379032
-
The melanocortin-3 receptor is required for entrainment to meal intake
-
Sutton, G.M., Perez-Tilve, D., Nogueiras, R., Fang, J., Kim, J.K., Cone, R.D., Gimble, J.M., Tschop, M.H., Butler, A.A., 2008. The melanocortin-3 receptor is required for entrainment to meal intake. J. Neurosci. 28, 12946-12955.
-
(2008)
J. Neurosci.
, vol.28
, pp. 12946-12955
-
-
Sutton, G.M.1
Perez-Tilve, D.2
Nogueiras, R.3
Fang, J.4
Kim, J.K.5
Cone, R.D.6
Gimble, J.M.7
Tschop, M.H.8
Butler, A.A.9
-
81
-
-
77952307945
-
Central nervous system melanocortin-3 receptors are required for synchronizing metabolism during entrainment to restricted feeding during the light cycle
-
Sutton, G.M., Begriche, K., Kumar, K.G., Gimble, J.M., Perez-Tilve, D., Nogueiras, R., McMillan, R.P., Hulver, M.W., Tschop, M.H., Butler, A.A., 2010. Central nervous system melanocortin-3 receptors are required for synchronizing metabolism during entrainment to restricted feeding during the light cycle. FASEB J. 24, 862-872.
-
(2010)
FASEB J.
, vol.24
, pp. 862-872
-
-
Sutton, G.M.1
Begriche, K.2
Kumar, K.G.3
Gimble, J.M.4
Perez-Tilve, D.5
Nogueiras, R.6
McMillan, R.P.7
Hulver, M.W.8
Tschop, M.H.9
Butler, A.A.10
-
82
-
-
4043093705
-
Functional characterization of melanocortin-3 receptor variants identify a loss-of-function mutation involving an amino acid critical for G protein-coupled receptor activation
-
Tao, Y.X., Segaloff, D.L., 2004. Functional characterization of melanocortin-3 receptor variants identify a loss-of-function mutation involving an amino acid critical for G protein-coupled receptor activation. J. Clin. Endocrinol. Metab. 89, 3936-3942.
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 3936-3942
-
-
Tao, Y.X.1
Segaloff, D.L.2
-
83
-
-
38049089037
-
Role of adiponectin and inflammation in insulin resistance of Mc3r and Mc4r knockout mice
-
Silver Spring
-
Trevaskis, J.L., Gawronska-Kozak, B., Sutton, G.M., McNeil, M., Stephens, J.M., Smith, S.R., Butler, A.A., 2007. Role of adiponectin and inflammation in insulin resistance of Mc3r and Mc4r knockout mice. Obesity (Silver Spring) 15, 2664-2672.
-
(2007)
Obesity
, vol.15
, pp. 2664-2672
-
-
Trevaskis, J.L.1
Gawronska-Kozak, B.2
Sutton, G.M.3
McNeil, M.4
Stephens, J.M.5
Smith, S.R.6
Butler, A.A.7
-
84
-
-
0027423948
-
Hereditary isolated glucocorticoid-deficiency is associated with abnormalities of the adrenocorticotropin receptor gene
-
Tsigos, C., Arai, K., Hung, W., Chrousos, G.P., 1993. Hereditary isolated glucocorticoid-deficiency is associated with abnormalities of the adrenocorticotropin receptor gene. J. Clin. Invest. 92, 2458-2461.
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 2458-2461
-
-
Tsigos, C.1
Arai, K.2
Hung, W.3
Chrousos, G.P.4
-
85
-
-
20844461135
-
Obesity and metabolic syndrome in circadian Clock mutant nice
-
DOI 10.1126/science.1108750
-
Turek, F.W., Joshu, C., Kohsaka, A., Lin, E., Ivanova, G., McDearmon, E., Laposky, A., Losee-Olson, S., Easton, A., Jensen, D.R., Eckel, R.H., Takahashi, J.S., Bass, J., 2005. Obesity and metabolic syndrome in circadian Clock mutant mice. Science 308, 1043-1045. (Pubitemid 40664419)
-
(2005)
Science
, vol.308
, Issue.5724
, pp. 1043-1045
-
-
Turek, F.W.1
Joshu, C.2
Kohsaka, A.3
Lin, E.4
Ivanova, G.5
McDearmon, E.6
Laposky, A.7
Losee-Olson, S.8
Easton, A.9
Jensen, D.R.10
Eckel, R.H.11
Takahashi, J.S.12
Bass, J.13
-
86
-
-
0033927916
-
Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity
-
Vaisse, C., Clement, K., Durand, E., Hercberg, S., Guy-Grand, B., Froguel, P., 2000. Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity. J. Clin. Invest. 106, 253-262.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 253-262
-
-
Vaisse, C.1
Clement, K.2
Durand, E.3
Hercberg, S.4
Guy-Grand, B.5
Froguel, P.6
-
87
-
-
0028786945
-
Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans
-
Valverde, P., Healy, E., J., I., J.L., R., Thody, A.J., 1995. Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans. Nat. Genet. 11, 328-330.
-
(1995)
Nat. Genet.
, vol.11
, pp. 328-330
-
-
Valverde, P.1
Healy, E.2
J, I.3
JL, R.4
Thody, A.J.5
-
88
-
-
0036021083
-
Melanocortin-3 receptor gene variants in a Maori kindred with obesity and early onset type 2 diabetes
-
Wong, J., Love, D.R., Kyle, C., Daniels, A., White, M., Stewart, A.W., Schnell, A.H., Elston, R.C., Holdaway, I.M., Mountjoy, K.G., 2002. Melanocortin-3 receptor gene variants in a Maori kindred with obesity and early onset type 2 diabetes. Diab. Res. Clin. Pract. 58, 61-71.
-
(2002)
Diab. Res. Clin. Pract.
, vol.58
, pp. 61-71
-
-
Wong, J.1
Love, D.R.2
Kyle, C.3
Daniels, A.4
White, M.5
Stewart, A.W.6
Schnell, A.H.7
Elston, R.C.8
Holdaway, I.M.9
Mountjoy, K.G.10
-
89
-
-
0030980505
-
Postnatal expression of melanocortin-3 receptor in rat diencephalon and mesencephalon
-
DOI 10.1016/S0028-3908(96)00151-7, PII S0028390896001517
-
Xia, Y., Wikberg, J.E.S., 1997. Postnatal expression of melanocortin-3 receptor in ratdiencephalon and mesencephalon. Neuropharmacology 36, 217-224. (Pubitemid 27149510)
-
(1997)
Neuropharmacology
, vol.36
, Issue.2
, pp. 217-224
-
-
Xia, Y.1
Wikberg, J.E.S.2
-
90
-
-
0037036419
-
Molecular determinants of human melanocortin-4 receptor responsible for antagonist SHU9119 selective activity
-
Yang, Y., Chen, M., Lai, Y., Gantz, I., Georgeson, K.E., Harmon, C.M., 2002. Molecular determinants of human melanocortin-4 receptor responsible for antagonist SHU9119 selective activity. J. Biol. Chem. 277, 20328-20335.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 20328-20335
-
-
Yang, Y.1
Chen, M.2
Lai, Y.3
Gantz, I.4
Georgeson, K.E.5
Harmon, C.M.6
|