The dichloroacetate dilemma: Environmental hazard versus therapeutic Goldmine-both or neither?

Environmental Health Perspectives

Volumn 119, Issue 2, 2011, Pages 155-158

  Stacpoole, Peter W ^a,b  

^a Division of Endocrinology and Metabolism   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Cancer; Dichloroacetate; Glutathione transferase zeta; Hereditary tyrosinemia; Maleylacetoacetate isomerase; Mitochondrial disease; Peripheral neuropathy; Pyruvate dehydrogenase; Toxicogenetics

Indexed keywords

DICHLOROACETIC ACID; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE ZETA 1; GLYOXYLIC ACID; ISOMERASE; MALEYLACETOACETATE ISOMERASE; PHENYLALANINE; TYROSINE; UNCLASSIFIED DRUG;

AGE; BIOTRANSFORMATION; ENZYME DEGRADATION; HAPLOTYPE; HEALTH HAZARD; HUMAN; LIVER TOXICITY; LONG TERM EXPOSURE; NEUROTOXICITY; NONHUMAN; NOTE; PLASMA CLEARANCE; PRIORITY JOURNAL; RODENT; TOXICOGENETICS; TOXICOKINETICS; ARTICLE; DRUG EFFECT; LIVER; NERVOUS SYSTEM;

ANIMALIA; RODENTIA;

DICHLOROACETATE; HUMANS; LIVER; NERVOUS SYSTEM;

EID: 79955826967     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1002554     Document Type: Note

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