Alkylation and inactivation of human glutathione transferase zeta (hGSTZ1-1) by maleylacetone and fumarylacetone

Chemical Research in Toxicology

Volumn 15, Issue 5, 2002, Pages 707-716

  Lantum, Hoffman B M ^a   Liebler, Daniel C ^b   Board, Philip G ^c   Anders, M W ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c Biology and Environment   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONE; DICHLOROACETIC ACID; FUMARYLACETONE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE ZETA; MALEYLACETONE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; BIOTRANSFORMATION; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; COVALENT BOND; ENZYME ACTIVE SITE; ENZYME INACTIVATION; HUMAN; HUMAN CELL; ISOMERISM; PATHOGENESIS; PROTEIN FAMILY; TANDEM MASS SPECTROMETRY; TIME SERIES ANALYSIS; TYROSINEMIA;

ACETONE; ALKYLATION; DRUG INTERACTIONS; ENZYME INHIBITORS; FUMARATES; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; MALEATES;

EID: 0036093186     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx025503s     Document Type: Article

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