Inhibition and recovery of rat hepatic glutathione S-transferase zeta and alteration of tyrosine metabolism following dichloroacetate exposure and withdrawal

Drug Metabolism and Disposition

Volumn 34, Issue 1, 2006, Pages 36-42

  Guo, Xu ^a   Dixit, Vaishali ^b   Liu, Huiping ^a   Shroads, Albert L ^a   Henderson, George N ^a   James, Margaret O ^b   Stacpoole, Peter W ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONE; DICHLOROACETIC ACID; DRINKING WATER; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE ZETA; MALEYLACETONE; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DOSE RESPONSE; DRUG EXPOSURE; DRUG MEGADOSE; DRUG WITHDRAWAL; ENZYME ACTIVITY; ENZYME INHIBITION; LIVER WEIGHT; MALE; METABOLITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; URINALYSIS; URINARY EXCRETION; WESTERN BLOTTING;

ACETONE; ADMINISTRATION, ORAL; AGING; ANIMALS; BLOTTING, WESTERN; BODY WEIGHT; DICHLOROACETATE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRINKING; DRUG ADMINISTRATION SCHEDULE; GLUTATHIONE TRANSFERASE; HUMANS; LIVER; MALE; MALEATES; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; TYROSINE;

ANIMALIA;

EID: 29944435172     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.105.003996     Document Type: Article

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