Mitochondrion as a novel site of dichloroacetate biotransformation by glutathione transferase ζ1

Journal of Pharmacology and Experimental Therapeutics

Volumn 336, Issue 1, 2011, Pages 87-94

  Li, Wenjun ^a   James, Margaret O ^a   McKenzie, Sarah C ^a   Calcutt, Nigel A ^c   Liu, Chen ^a   Stacpoole, Peter W ^b  

^a UNIVERSITY OF FLORIDA HEALTH   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DICHLOROACETIC ACID; GLUTATHIONE; GLUTATHIONE TRANSFERASE ZETA1; TRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATALYSIS; CYTOSOL; DECHLORINATION; DRUG TRANSFORMATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; LIQUID CHROMATOGRAPHY; LIVER MITOCHONDRION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TANDEM MASS SPECTROMETRY;

ANIMALS; BIOTRANSFORMATION; CATALYSIS; CYTOSOL; DICHLOROACETATE; EXTRACELLULAR MATRIX; FEMALE; GLUTATHIONE TRANSFERASE; HUMANS; MALE; MITOCHONDRIA, LIVER; RATS; XENOBIOTICS;

EID: 78650796196     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.173195     Document Type: Article

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