Glutathione transferase zeta-catalyzed bioactivation of dichloroacetic acid: Reaction of glyoxylate with amino acid nucleophiles

Chemical Research in Toxicology

Volumn 17, Issue 5, 2004, Pages 650-662

  Anderson, Wayne B ^a   Board, Philip G ^b   Anders, M W ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b Biology and Environment   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETOACETIC ACID; AMINO ACID; ANTIFLAMMIN 2; BOVINE SERUM ALBUMIN; DICHLOROACETIC ACID; DRINKING WATER; FLUORINE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE ZETA; GLYOXYLIC ACID; IMIDAZOLIDINE DERIVATIVE; INTERLEUKIN 8; UNCLASSIFIED DRUG;

ADDITION REACTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BIOTRANSFORMATION; CARCINOGENICITY; CHLORINATION; CONTROLLED STUDY; CYTOSOLIC FRACTION; ELIMINATION REACTION; ISOMERIZATION; LACTIC ACIDOSIS; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; RAT; WATER CONTAMINATION;

ACETOACETATES; AMINES; AMINO ACIDS; ANIMALS; BIOTRANSFORMATION; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOSOL; DICHLOROACETATE; GLUTATHIONE TRANSFERASE; GLYCOLATES; HYDROLYSIS; ISOMERISM; KINETICS; LIVER; LYSINE; MASS SPECTROMETRY; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; RATS;

ANIMALIA; BOVINAE; RODENTIA;

EID: 2442666573     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx034099+     Document Type: Article

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