Age-dependent kinetics and metabolism of dichloroacetate: Possible relevance to toxicity

Journal of Pharmacology and Experimental Therapeutics

Volumn 324, Issue 3, 2008, Pages 1163-1171

  Shroads, Albert L ^a   Guo, Xu ^a   Dixit, Vaishali ^b   Liu, Hui Ping ^a   James, Margaret O ^b   Stacpoole, Peter W ^a,b,c  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c UNIVERSITY OF FLORIDA HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONE; CHLOROACETIC ACID; DICHLOROACETIC ACID; GLUTATHIONE TRANSFERASE ZETA 1; LIVER PROTEIN; MALEYLACETOACETATE ISOMERASE; MALEYLACETONE; OXALIC ACID; TYROSINE; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG METABOLISM; DRUG STRUCTURE; DRUG TRANSFORMATION; DRUG URINE LEVEL; ENZYME ACTIVITY; HUMAN; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METABOLISM; RAT;

ADOLESCENT; ADULT; AGING; ANIMALS; CHILD; CHILD, PRESCHOOL; DICHLOROACETATE; HUMANS; MALE; METABOLIC NETWORKS AND PATHWAYS; PROSPECTIVE STUDIES; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RATS; RATS, SPRAGUE-DAWLEY;

EID: 40849111674     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.134593     Document Type: Article

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