Microsomal glutathione transferase 1: Mechanism and functional roles

Drug Metabolism Reviews

Volumn 43, Issue 2, 2011, Pages 300-306

  Morgenstern, Ralf ^a   Zhang, Jie ^a   Johansson, Katarina ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

drug resistance; expression; fluorescent substrates; mechanism; Microsomal glutathione transferase; structure function

Indexed keywords

2,4 DINITROBENZENESULFONYL RHODAMINE; 6 CHLOROACETYL 2 DIMETHYLAMINONAPHTHALENE; ACETYLCYSTEINE; CHLORAMBUCIL; CISPLATIN; DOXORUBICIN; GEMCITABINE; GLUTATHIONE TRANSFERASE; GLYCERYL TRINITRATE; MELPHALAN; MICROSOMAL GLUTATHIONE TRANSFERASE 1; NAPHTHALENE DERIVATIVE; RHODAMINE; UNCLASSIFIED DRUG;

CANCER RESISTANCE; CARCINOGENESIS; CELL PROTECTION; DRUG METABOLISM; DRUG TRANSFORMATION; ENZYME MECHANISM; EWING SARCOMA; HUMAN; METASTASIS; NONHUMAN; OXIDATIVE STRESS; PANCREAS CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; UPREGULATION;

ANIMALS; BINDING SITES; DRUG RESISTANCE; GLUTATHIONE TRANSFERASE; HUMANS; ISOENZYMES; METABOLIC DETOXICATION, DRUG; MODELS, MOLECULAR; NEOPLASMS; OXIDATIVE STRESS; PHARMACEUTICAL PREPARATIONS; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

EID: 79954597286     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.3109/03602532.2011.558511     Document Type: Review

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