Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents

Drug Metabolism Reviews

Volumn 43, Issue 2, 2011, Pages 92-137

  Higgins, Larry G ^a   Hayes, John D ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

AhR (Aryl hydrocarbon Receptor); ARE (Antioxidant Response Element); CAR (Constitutive Androstane Receptor); Chemoprevention; EpRE (Electrophile Response Element); GPEI (Glutathione transferase P Enhancer I); GRE (Glucocorticoid Response Element); GSH (reduced glutathione); Keap1 (Kelch like ECH associated protein 1); Nrf2 (NF E2 related factor 2); PBREM (Phenobarbital Responsive Enhancer Module); tBHQ (tert butylhydroquinone); XRE (Xenobiotic Response Element)

Indexed keywords

1 [2 CYANO 3,12 DIOXOOLEANA 1,9(11) DIEN 28 OYL]IMIDAZOLE; 1,4 BIS(3,5 DICHLORO 2 PYRIDYLOXY)BENZENE; 16ALPHA CYANOPREGNENOLONE; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 2,4 THIAZOLIDINEDIONE DERIVATIVE; 3 METHYLCHOLANTHRENE; ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN; AROMATIC HYDROCARBON RECEPTOR; BETA NAPHTHOFLAVONE; BUTYLATED HYDROXYANISOLE; CCAAT ENHANCER BINDING PROTEIN; CONSTITUTIVE ANDROSTANE RECEPTOR; COUMARIN; DEXAMETHASONE; ETHOXYQUIN; FUMARIC ACID; GLUTATHIONE TRANSFERASE; IMIDAZOLE; LEUKOTRIENE C4 SYNTHASE; MICROSOMAL GLUTATHIONE TRANSFERASE; MITOCHONDRIAL GLUTATHIONE TRANSFERASE; OLTIPRAZ; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHENOBARBITAL; PHORBOL 13 ACETATE 12 MYRISTATE; PREGNANE X RECEPTOR; SULFORAPHANE; TRANSCRIPTION FACTOR NF E2; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

AMINO ACID SEQUENCE; BIOINFORMATICS; CYTOSOL; DRUG EFFECT; DRUG METABOLISM; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INDUCTION; ENZYME SPECIFICITY; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; LIVER MICROSOME; MOLECULAR CLONING; MOLECULAR INTERACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN FUNCTION; REVIEW; UPREGULATION; XENOBIOTIC METABOLISM;

ANIMALS; CYTOSOL; ENZYME INDUCTION; GENE EXPRESSION; GLUTATHIONE TRANSFERASE; HUMANS; INFLAMMATION MEDIATORS; MICROSOMES; MOLECULAR STRUCTURE; SUBSTRATE SPECIFICITY; XENOBIOTICS;

EID: 79954574488     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.3109/03602532.2011.567391     Document Type: Review

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