Gene expression analysis for predicting gemcitabine sensitivity in pancreatic cancer patients

HPB

Volumn 9, Issue 2, 2007, Pages 150-155

  Bai, Jianfeng ^a,b   Sata, Naohiro ^a   Nagai, Hideo ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Drug resistance; Gemcitabine; Microarray; Pancreatic cancer

Indexed keywords

GEMCITABINE; RNA;

ADULT; AGED; ARTICLE; CANCER CELL; CELL ISOLATION; CLINICAL ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG SENSITIVITY; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; PANCREAS CANCER; PREDICTION; RNA EXTRACTION; SCORING SYSTEM;

EID: 34247569912     PISSN: 1365182X     EISSN: 14772574     Source Type: Journal    
DOI: 10.1080/13651820601175918     Document Type: Article

References (20)

1. (2001) pp. 1126-1161. Lippincott Williams and Wilkins
2. Do, JK, Kubota, T., Ura, HT, Yamaue, H., Akiyama, S. and Maehara, Y. (2000) Cumulative results of chemosensitivity tests for antitumor agents in Japan. Anticancer Res, 20, pp. 2389-2392.
3. Kobayshi, H., Tanisaka, K., Kondo, N., Mito, Y., Koezuka, M. and Yokouchi, H. (1995) Development of new in vitro chemosensitivity test using collagen gel droplet embedded culture and its clinical usefulness. Gan To Kagaku Ryoho, 22:13, pp. 1933-1939.
4. Assersohn, L., Gangi, L., Zhao, Y., Dowsett, M., Simon, R. and Powles, TJ (2002) The feasibility of using fine needle aspiration from primary breast cancer for cDNA microarray analyses. Clin Cancer Res, 8, pp. 794-801.
5. Yasuda, H., Takada, T., Wada, K., Amano, H., Isaka, T. and Yoshida, M. (1998) A new in-vitro drug sensitivity test (collagen-gel droplet embedded-culture drug sensitivity test) in carcinomas of pancreas and biliary tract: Possible clinical utility. J Hepatobiliary Pancreat Surg, 5, pp. 261-268.
6. Kobayashi, H. (2005) Collagen gel droplet culture method to examine in vitro chemosensitivity. Methods Mol Med, 110, pp. 59-67.
7. Plunkett, W., Huang, P., Searcy, CE and Gandhi, V. (1996) Gemcitabine: preclinical pharmacology and mechanisms of action. Semin Oncol, 23:5, pp. 3-15.
8. Scherf, U., Ross, DT, Waltham, M., Smith, LH, Lee, JK and Tanabe, L. (2000) A gene expression database for the molecular pharmacology of cancer. Nat Genet, 24, pp. 236-244.
9. Trizna, Z., Clayman, GL, Spitz, MR, Briggs, KL and Goefert, H. (1995) Glutathione s-transferase genotypes as risk factors for head and neck cancer. Am J Surg, 170, pp. 499-501.
10. Strange, RC, Lear, JT and Fryer, AA (1998) Glutathione s-transferase polymorphisms: Influence on susceptibility to cancer. Chem Biol Interact, 111, pp. 351-364.
11. Awasthi, S., Srivastava, SK, Ahmad, F., Ahmad, H. and Ansari, GA (1993) Interactions of glutathione s-transferase-pi with ethacrynic acid and its glutathione conjugate. Biochim Biophys Acta, 1164, pp. 173-178.
12. Payen, L., Sparfel, L., Courtois, A., Vernhet, L., Guillouzo, A. and Fardel, O. (2002) The drug efflux pump MRP2: Regulation of expression in physiopathological situations and by endogenous and exogenous compounds. Cell Biol Toxicol, 18, pp. 221-223.
13. Suzuki, H. and Sugiyama, Y. (2002) Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): Its impact on drug disposition. Adv Drug Deliv Rev, 54, pp. 1311-1331.
14. Holden, JK (1997) Human deoxyribonucleic acid topoisomerase: Molecular targets of anticancer drugs. Ann Clin Lab Sci, 27, pp. 402-412.
15. Pommier, Y., Leteurte, F., Fesen, MR, Fujimori, A., Bertrand, R. and Solary, E. (1994) Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors. Cancer Invest, 12, pp. 530-542.
16. Matsumoto, Y., Takano, H., Kunishio, K., Nagao, S. and Fojo, T. (2001) Hypophosphorylation of topoisomerase II alpha in etoposide (VP-16)-resistant human carcinoma cell lines associated with carboxy-terminal truncation. Jpn J Cancer Res, 92, pp. 799-805.
17. Dive, C. and Hickman, JA (1991) Drug-target interactions: Only the first step in the commitment to a programmed cell death?. Br J Cancer, 64, pp. 192-196.
18. Basu, A., Castle, VP, Bouziane, M., Bhalla, K. and Haldar, S. (2006) Crosstalk between extrinsic and intrinsic cell death pathways in pancreatic cancer: Synergistic action of estrogen metabolite and ligands of death receptor family. Cancer Res, 66, pp. 4309-4318.
19. Yang, XH, Sladek, TL, Liu, X., Butler, BR, Froelich, CJ and Thor, AD (2001) Reconstitution of caspase sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis. Cancer Res, 61, pp. 348-354.
20. Kihara, C., Tsunoda, T., Tanaka, T., Yamana, H., Furukawa, Y. and Ono, K. (2001) Prediction of sensitivity of esophageal tumors to adjuvant chemotherapy by cDNA microarray analysis of gene-expression profiles. Cancer Res, 61, pp. 6474-6479.