메뉴 건너뛰기




Volumn 48, Issue 6, 2003, Pages 623-630

Relationship between activation of microsomal glutathione S-transferase and metabolism behavior of chlorambucil

Author keywords

Acquired drug resistance; Chlorambucil; Microsomal glutathione S transferases

Indexed keywords

4 [4 [BIS(2 S GLUTATHIONYLETHYL)AMINO]PHENYL]BUTANOIC ACID; 4 [4 [N 2 CHLOROETHYL N (2 S GLUTATHIONYLETHYLETHYL)AMINO]PHENYL]BUTANOIC ACID; 4 [4 [N 2 S GLUTATHIONYLETHYL N (2 HYDROXYETHYL)AMINO]PHENYL]BUTANOIC ACID; ALKYLATING AGENT; CHLORAMBUCIL; CYSTEINE; GLUTATHIONE; GLUTATHIONE DERIVATIVE; GLUTATHIONE TRANSFERASE; UNCLASSIFIED DRUG;

EID: 1542502680     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-6618(03)00247-0     Document Type: Article
Times cited : (8)

References (35)
  • 1
    • 0025196194 scopus 로고
    • Characterization of glutathione conjugates of chlorambucil by fast atom bombardment and thermospray liquid chromatography/mass spectrometry
    • Dulik D.M., Colvin O.M., Fenselau C. Characterization of glutathione conjugates of chlorambucil by fast atom bombardment and thermospray liquid chromatography/mass spectrometry. Biomed. Environ. Mass Spectrom. 19:1990;248-252.
    • (1990) Biomed. Environ. Mass Spectrom. , vol.19 , pp. 248-252
    • Dulik, D.M.1    Colvin, O.M.2    Fenselau, C.3
  • 2
    • 0036176510 scopus 로고    scopus 로고
    • Mechanisms of cancer drug resistance
    • Gottesman M.M. Mechanisms of cancer drug resistance. Annu. Rev. Med. 53:2002;615-627.
    • (2002) Annu. Rev. Med. , vol.53 , pp. 615-627
    • Gottesman, M.M.1
  • 3
    • 0029561598 scopus 로고
    • The glutathione S-transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
    • Hayes J.D., Pulford D.J. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit. Rev. Biochem. Mol. Biol. 30:1995;445-600.
    • (1995) Crit. Rev. Biochem. Mol. Biol. , vol.30 , pp. 445-600
    • Hayes, J.D.1    Pulford, D.J.2
  • 4
    • 0021127473 scopus 로고
    • Glutathione metabolism as a determinant of therapeutic efficacy: A review
    • Arrick B.A., Nathan C.F. Glutathione metabolism as a determinant of therapeutic efficacy: a review. Cancer Res. 44:1984;4224-4232.
    • (1984) Cancer Res. , vol.44 , pp. 4224-4232
    • Arrick, B.A.1    Nathan, C.F.2
  • 5
    • 0025786879 scopus 로고
    • Enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferases and inhibition by ethacrynic acid
    • Ciaccio P.J., Tew K.D., LaCreta F.P. Enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferases and inhibition by ethacrynic acid. Biochem. Pharmacol. 42:1991;1504-1507.
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 1504-1507
    • Ciaccio, P.J.1    Tew, K.D.2    Lacreta, F.P.3
  • 6
    • 0022525561 scopus 로고
    • Characterization of melphalan-glutathione adducts whose formation is catalyzed by glutathione transferases
    • Dulik D., Fenselau C., Hilton J. Characterization of melphalan- glutathione adducts whose formation is catalyzed by glutathione transferases. Biochem. Pharmacol. 35:1986;3405-3409.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 3405-3409
    • Dulik, D.1    Fenselau, C.2    Hilton, J.3
  • 7
    • 0028910538 scopus 로고
    • The role of human glutathione S-transferase isoenzymes in the formation of glutathione conjugates of the alkylating cytostatic drug thiotepa
    • Dirven H.A., Dictus E.L., Broeders N.L., van-Ommen B., van-Bladeren P.J. The role of human glutathione S-transferase isoenzymes in the formation of glutathione conjugates of the alkylating cytostatic drug thiotepa. Cancer Res. 55:1995;1701-1706.
    • (1995) Cancer Res. , vol.55 , pp. 1701-1706
    • Dirven, H.A.1    Dictus, E.L.2    Broeders, N.L.3    Van-Ommen, B.4    Van-Bladeren, P.J.5
  • 8
    • 0029954846 scopus 로고    scopus 로고
    • Glutathione and related enzymes in multidrug resistance
    • O'Brien M.L., Tew K.D. Glutathione and related enzymes in multidrug resistance. Eur. J. Cancer. 32:1996;967-978.
    • (1996) Eur. J. Cancer , vol.32 , pp. 967-978
    • O'Brien, M.L.1    Tew, K.D.2
  • 9
    • 0031939392 scopus 로고    scopus 로고
    • Glutathione-related mechanisms in cellular resistance to anticancer drugs
    • Zhang K., Mack P., Wong K.P. Glutathione-related mechanisms in cellular resistance to anticancer drugs. Int. J. Oncol. 12:1998;871-882.
    • (1998) Int. J. Oncol. , vol.12 , pp. 871-882
    • Zhang, K.1    MacK, P.2    Wong, K.P.3
  • 10
    • 0021889194 scopus 로고
    • Increased glutathione-S-transferase activity in a cell line with acquired resistance to nitrogen mustards
    • Wang A.L., Tew K.D. Increased glutathione-S-transferase activity in a cell line with acquired resistance to nitrogen mustards. Cancer Treat. Rep. 69:1985;677-682.
    • (1985) Cancer Treat. Rep. , vol.69 , pp. 677-682
    • Wang, A.L.1    Tew, K.D.2
  • 11
    • 0033567422 scopus 로고    scopus 로고
    • Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase μ
    • Horton J.K., Roy G., Piper J.T., Van H.B., Awasthi Y.C., Mitra S. Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase μ Biochem. Pharmacol. 58:1999;693-702.
    • (1999) Biochem. Pharmacol. , vol.58 , pp. 693-702
    • Horton, J.K.1    Roy, G.2    Piper, J.T.3    Van, H.B.4    Awasthi, Y.C.5    Mitra, S.6
  • 12
    • 0024322933 scopus 로고
    • Glutathione and glutathione S-transferases in a human plasma cell line resistant to melphalan
    • Gupta V., Singh S.V., Ahmad H., Medh R.D., Awasthi Y.C. Glutathione and glutathione S-transferases in a human plasma cell line resistant to melphalan. Biochem. Pharmacol. 38:1989;1993-2000.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 1993-2000
    • Gupta, V.1    Singh, S.V.2    Ahmad, H.3    Medh, R.D.4    Awasthi, Y.C.5
  • 13
    • 0021721547 scopus 로고
    • Potentiation of melphalan cytotoxicity in human ovarian cancer cell lines by glutathione depletion
    • Green J.A., Vistica D.T., Young R.C., Hamilton T.C., Rogan A.M., Ozols R.F. Potentiation of melphalan cytotoxicity in human ovarian cancer cell lines by glutathione depletion. Cancer Res. 44:1984;5427-5431.
    • (1984) Cancer Res. , vol.44 , pp. 5427-5431
    • Green, J.A.1    Vistica, D.T.2    Young, R.C.3    Hamilton, T.C.4    Rogan, A.M.5    Ozols, R.F.6
  • 14
    • 0023679751 scopus 로고
    • Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines
    • Tew K.D., Bomber A.M., Hoffman S.J. Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines. Cancer Res. 48:1988;3622-3625.
    • (1988) Cancer Res. , vol.48 , pp. 3622-3625
    • Tew, K.D.1    Bomber, A.M.2    Hoffman, S.J.3
  • 15
    • 0026027666 scopus 로고
    • Sensitization of human melanoma cells to the cytotoxic effect of melphalan by the glutathione transferase inhibitor ethacrynic acid
    • Hansson J., Berhane K., Castro V.M., Jungnelius U., Mannervik B., Ringborg U. Sensitization of human melanoma cells to the cytotoxic effect of melphalan by the glutathione transferase inhibitor ethacrynic acid. Cancer Res. 51:1991;94-98.
    • (1991) Cancer Res. , vol.51 , pp. 94-98
    • Hansson, J.1    Berhane, K.2    Castro, V.M.3    Jungnelius, U.4    Mannervik, B.5    Ringborg, U.6
  • 17
    • 0025317653 scopus 로고
    • Expression of recombinant glutathione S-transferase pi, Ya, or Yb1 confers resistance to alkylating agents
    • Puchalski R.B., Fahl W.E. Expression of recombinant glutathione S-transferase pi, Ya, or Yb1 confers resistance to alkylating agents. Proc. Natl. Acad. Sci. U.S.A. 87:1990;2443-2447.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 2443-2447
    • Puchalski, R.B.1    Fahl, W.E.2
  • 18
    • 0025237403 scopus 로고
    • Glutathione-S-transferase pi as a determinant of drug resistance in transfectant cell lines
    • Nakagawa K., Saijo N., Tsuchida S., Sakai M., Tsunokawa Y., Yokota J.et al. Glutathione-S-transferase pi as a determinant of drug resistance in transfectant cell lines. J. Biol. Chem. 265:1990;4296-4301.
    • (1990) J. Biol. Chem. , vol.265 , pp. 4296-4301
    • Nakagawa, K.1    Saijo, N.2    Tsuchida, S.3    Sakai, M.4    Tsunokawa, Y.5    Yokota, J.6
  • 19
    • 0020209472 scopus 로고
    • Microsomal glutathione S-transferase. Purification, initial characterization and demonstration that it is not identical to the cytosolic glutathione S-transferases A, B and C
    • Morgenstern R., Guthenberg C., DePierre J.W. Microsomal glutathione S-transferase. Purification, initial characterization and demonstration that it is not identical to the cytosolic glutathione S-transferases A, B and C. Eur. J. Biochem. 128:1982;243-248.
    • (1982) Eur. J. Biochem. , vol.128 , pp. 243-248
    • Morgenstern, R.1    Guthenberg, C.2    Depierre, J.W.3
  • 20
    • 0021677474 scopus 로고
    • The distribution of microsomal glutathione transferase among different organelles, different organs and different organisms
    • Morgenstern R., Lundqvist G., Andersson G., Balk L., DePierre J.W. The distribution of microsomal glutathione transferase among different organelles, different organs and different organisms. Biochem. Pharmacol. 33:1984;3609-3614.
    • (1984) Biochem. Pharmacol. , vol.33 , pp. 3609-3614
    • Morgenstern, R.1    Lundqvist, G.2    Andersson, G.3    Balk, L.4    Depierre, J.W.5
  • 21
    • 0022350225 scopus 로고
    • Microsomal glutathione transferase. Primary structure
    • Morgenstern R., DePierre J.W., Jornvall H. Microsomal glutathione transferase. Primary structure. J. Biol. Chem. 260:1985;13976-13983.
    • (1985) J. Biol. Chem. , vol.260 , pp. 13976-13983
    • Morgenstern, R.1    Depierre, J.W.2    Jornvall, H.3
  • 22
    • 0023006908 scopus 로고
    • Radiation inactivation of microsomal glutathione S-transferase
    • Boyer T.D., Vessey D.A., Kempner E. Radiation inactivation of microsomal glutathione S-transferase. J. Biol. Chem. 261:1986;16963-16968.
    • (1986) J. Biol. Chem. , vol.261 , pp. 16963-16968
    • Boyer, T.D.1    Vessey, D.A.2    Kempner, E.3
  • 23
    • 0026784009 scopus 로고
    • The oligomeric structure of rat liver microsomal glutathione transferase studied by chemical cross-linking
    • Lundqvist G., Yucel-Lindberg T., Morgenstern R. The oligomeric structure of rat liver microsomal glutathione transferase studied by chemical cross-linking. Biochim. Biophys. Acta. 1159:1992;103-108.
    • (1992) Biochim. Biophys. Acta. , vol.1159 , pp. 103-108
    • Lundqvist, G.1    Yucel-Lindberg, T.2    Morgenstern, R.3
  • 24
    • 0030882948 scopus 로고    scopus 로고
    • Binding of glutathione and an inhibitor to microsomal glutathione transferase
    • Sun T.H., Morgenstern R. Binding of glutathione and an inhibitor to microsomal glutathione transferase. Biochem. J. 326:1997;193-196.
    • (1997) Biochem. J. , vol.326 , pp. 193-196
    • Sun, T.H.1    Morgenstern, R.2
  • 25
    • 0024321876 scopus 로고
    • Activation of rat liver microsomal glutathione transferase by limited proteolysis
    • Morgenstern R., Lundqvist G., Jornvall H., DePierre J.W. Activation of rat liver microsomal glutathione transferase by limited proteolysis. Biochem. J. 260:1989;577-582.
    • (1989) Biochem. J. , vol.260 , pp. 577-582
    • Morgenstern, R.1    Lundqvist, G.2    Jornvall, H.3    Depierre, J.W.4
  • 26
    • 0018789315 scopus 로고
    • Activation of microsomal glutathione S-transferase activity by sulfhydryl reagents
    • Morgenstern R., DePierre J.W., Ernster L. Activation of microsomal glutathione S-transferase activity by sulfhydryl reagents. Biochem. Biophys. Res. Commun. 87:1979;657-663.
    • (1979) Biochem. Biophys. Res. Commun. , vol.87 , pp. 657-663
    • Morgenstern, R.1    Depierre, J.W.2    Ernster, L.3
  • 27
    • 0027156695 scopus 로고
    • Identification of a hepatic plasma membrane glutathione S-transferase activated by N-ethylmaleimide
    • Martina E.H., Helmut S., Theodorus P.M.A. Identification of a hepatic plasma membrane glutathione S-transferase activated by N-ethylmaleimide. Biochim. Biophys. Acta. 1148:1993;61-66.
    • (1993) Biochim. Biophys. Acta. , vol.1148 , pp. 61-66
    • Martina, E.H.1    Helmut, S.2    Theodorus, P.M.A.3
  • 28
    • 84988106922 scopus 로고
    • Enzyme-structure relationships in the endoplasmic reticulum of rat liver
    • Ernster L., Siekewitz P., Palade G.E. Enzyme-structure relationships in the endoplasmic reticulum of rat liver. J. Cell Biol. 15:1962;541-562.
    • (1962) J. Cell Biol. , vol.15 , pp. 541-562
    • Ernster, L.1    Siekewitz, P.2    Palade, G.E.3
  • 29
    • 0021104760 scopus 로고
    • Microsomal glutathione transferase. Purification in unactivated form and further characterization of the activation process, substrate specificity and amino acid composition
    • Morgenstern R., DePierre J.W. Microsomal glutathione transferase. Purification in unactivated form and further characterization of the activation process, substrate specificity and amino acid composition. Eur. J. Biochem. 134:1983;591-597.
    • (1983) Eur. J. Biochem. , vol.134 , pp. 591-597
    • Morgenstern, R.1    Depierre, J.W.2
  • 30
    • 0017613512 scopus 로고
    • A simplification of the protein assay method of Lowry et al. which is more generally applicable
    • Peterson G.L. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal. Biochem. 83:1977;346-356.
    • (1977) Anal. Biochem. , vol.83 , pp. 346-356
    • Peterson, G.L.1
  • 31
    • 0016275313 scopus 로고
    • Glutathione S-transferase: The first enzymatic step in mercapturic acid formation
    • Habig W.H., Pabst M.J., Jakoby W.B. Glutathione S-transferase: the first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249:1974;7130-7139.
    • (1974) J. Biol. Chem. , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 32
    • 0031172018 scopus 로고    scopus 로고
    • Separation of DL-dopa by means of micellar electrokinetic capillary chromatography after derivatization with Marfey's reagent
    • Wu G., Furlanut M. Separation of DL-dopa by means of micellar electrokinetic capillary chromatography after derivatization with Marfey's reagent. Pharmacol. Res. 35:1997;553-556.
    • (1997) Pharmacol. Res. , vol.35 , pp. 553-556
    • Wu, G.1    Furlanut, M.2
  • 33
    • 0033128171 scopus 로고    scopus 로고
    • LC/MS applications in drug development
    • Lee M.S., Kerns E.H. LC/MS applications in drug development. Mass. Spectrom. Rev. 18:1999;187-279.
    • (1999) Mass. Spectrom. Rev. , vol.18 , pp. 187-279
    • Lee, M.S.1    Kerns, E.H.2
  • 34
    • 0024356211 scopus 로고
    • Identification of a glutathione S-transferase associated with microsomes of tumor cells resistant to nitrogen mustards
    • Clapper M.L., Tew K.D. Identification of a glutathione S-transferase associated with microsomes of tumor cells resistant to nitrogen mustards. Biochem. Pharmacol. 38:1989;1915-1921.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 1915-1921
    • Clapper, M.L.1    Tew, K.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.