Human microsomal prostaglandin E synthase-1: Purification, functional characterization, and projection structure determination

Journal of Biological Chemistry

Volumn 278, Issue 25, 2003, Pages 22199-22209

  Thorén, Staffan ^a   Weinander, Rolf ^a   Saha, Sipra ^a   Jegerschöld, Caroline ^a   Pettersson, Pär L ^a   Samuelsson, Bengt ^a   Hebert, Hans ^a   Hamberg, Mats ^a   Morgenstern, Ralf ^a   Jakobsson, Per Johan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CELL IMMOBILIZATION; CRYSTALLOGRAPHY; ESCHERICHIA COLI; HYDRODYNAMICS; MOLECULAR STRUCTURE; MOLECULAR WEIGHT;

ELECTRON CRYSTALLOGRAPHY;

PROTEINS;

1 CHLORO 2,4 DINITROBENZENE; 15 HYDROPEROXYPROSTAGLANDIN E2; 5 HYDROPEROXY 6,8,11,14 ICOSATETRAENOIC ACID; CUMENE HYDROPEROXIDE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HISTIDINE; HYDROXYAPATITE; METAL; MICROSOME ENZYME; PEROXIDASE; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN E SYNTHASE 1; PROSTAGLANDIN G2; PROSTAGLANDIN SYNTHASE; RECOMBINANT ENZYME; TRIMERIC ENZYME; TRITON X 100; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONJUGATION; CRYSTALLOGRAPHY; ELECTRON CRYSTALLOGRAPHY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME PURIFICATION; ENZYME STRUCTURE; ESCHERICHIA COLI; HYDRODYNAMICS; IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY; MOLECULAR CLONING; MOLECULAR EVOLUTION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION;

ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; DINOPROSTONE; DNA PRIMERS; ENZYME STABILITY; ESCHERICHIA COLI; GLUTATHIONE; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; KINETICS; MICROSOMES; MOLECULAR WEIGHT; PEROXIDASES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0038266571     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M303227200     Document Type: Article

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