Huntington's Disease is a disorder of the corpus striatum: Focus on Rhes (Ras homologue enriched in the striatum)

Neuropharmacology

Volumn 60, Issue 7-8, 2011, Pages 1187-1192

  Subramaniam, Srinivasa ^a   Snyder, Solomon H ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Atrophy; HAP; HIP; Huntington Disease; mTOR; mutant Huntingtin; Rhes; Striatum

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; BENZODIAZEPINE RECEPTOR; BINDING PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; DEXRAS1 PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; HUNTINGTIN; HUNTINGTIN ASSOCIATED PROTEIN 1; HUNTINGTIN INTERACTING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MEMBRANE PROTEIN; RAS HOMOLOGUE ENRICHED IN THE STRIATUM; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; PROTIEN DEXRAS1; RAS HOMOLOGUE ENRICHED IN THE STRIATUM PROTEIN; RAS PROTEIN;

BRAIN ATROPHY; CORPUS STRIATUM; CYTOTOXICITY; GABAERGIC TRANSMISSION; HUMAN; HUNTINGTON CHOREA; MOTOR RETARDATION; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; REVIEW; SIGNAL TRANSDUCTION; SUMOYLATION; BRAIN CORTEX ATROPHY; DISEASE ASSOCIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; EXTRAPYRAMIDAL SYMPTOM; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; CORPUS STRIATUM; DNA-BINDING PROTEINS; GTP-BINDING PROTEINS; HUNTINGTON DISEASE; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TOR SERINE-THREONINE KINASES;

EID: 79954590400     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2010.10.025     Document Type: Review

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