-
1
-
-
0030878098
-
Fast transport and retrograde movement of huntingtin and HAP1 in axons
-
Block-Galarza J, Chase KO, Sapp E, Vaughn KT, Vallee RB, DiFiglia M, Aronin N (1997) Fast transport and retrograde movement of huntingtin and HAP1 in axons. NeuroReport 8:2247-2251.
-
(1997)
NeuroReport
, vol.8
, pp. 2247-2251
-
-
Block-Galarza, J.1
Chase, K.O.2
Sapp, E.3
Vaughn, K.T.4
Vallee, R.B.5
DiFiglia, M.6
Aronin, N.7
-
2
-
-
0035282594
-
Loss of normal huntingtin function: New developments in Huntington's disease research
-
Cattaneo E, Rigamonti D, Goffredo D, Zuccato C, Squitieri F, Sipione S (2001) Loss of normal huntingtin function: new developments in Huntington's disease research. Trends Neurosci 24:182-188.
-
(2001)
Trends Neurosci
, vol.24
, pp. 182-188
-
-
Cattaneo, E.1
Rigamonti, D.2
Goffredo, D.3
Zuccato, C.4
Squitieri, F.5
Sipione, S.6
-
3
-
-
0037091010
-
Targeted disruption of huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior
-
Chan EY, Nasir J, Gutekunst CA, Coleman S, Maclean A, Maas A, Metzler M, Gertsenstein M, Ross CA, Nagy A, Hayden MR (2002) Targeted disruption of huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior. Hum Mol Genet 11:945-959.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 945-959
-
-
Chan, E.Y.1
Nasir, J.2
Gutekunst, C.A.3
Coleman, S.4
Maclean, A.5
Maas, A.6
Metzler, M.7
Gertsenstein, M.8
Ross, C.A.9
Nagy, A.10
Hayden, M.R.11
-
4
-
-
0033551802
-
Interleukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways
-
Chen RH, Chang MC, Su YH, Tsai YT, Kuo ML (1999) Interleukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways. J Biol Chem 274:23013-23019.
-
(1999)
J Biol Chem
, vol.274
, pp. 23013-23019
-
-
Chen, R.H.1
Chang, M.C.2
Su, Y.H.3
Tsai, Y.T.4
Kuo, M.L.5
-
5
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
Davies SW, Turmaine M, Cozens BA, DiFiglia M, Sharp AH, Ross CA, Scherzinger E, Wanker EE, Mangiarini L, Bates GP (1997) Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell 90:537-548.
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
DiFiglia, M.4
Sharp, A.H.5
Ross, C.A.6
Scherzinger, E.7
Wanker, E.E.8
Mangiarini, L.9
Bates, G.P.10
-
6
-
-
0028598814
-
Murine FGFR-1 is required for early postimplantation growth and axial organization
-
Deng CX, Wynshaw-Boris A, Shen MM, Daugherty C, Ornitz DM, Leder P (1994) Murine FGFR-1 is required for early postimplantation growth and axial organization. Genes Dev 8:3045-3057.
-
(1994)
Genes Dev
, vol.8
, pp. 3045-3057
-
-
Deng, C.X.1
Wynshaw-Boris, A.2
Shen, M.M.3
Daugherty, C.4
Ornitz, D.M.5
Leder, P.6
-
7
-
-
0034677858
-
Expression of the huntingtin-associated protein 1 gene in the developing and adult mouse
-
Dragatsis I, Dietrich P, Zeitlin S (2000) Expression of the huntingtin-associated protein 1 gene in the developing and adult mouse. Neurosci Lett 282:37-40.
-
(2000)
Neurosci Lett
, vol.282
, pp. 37-40
-
-
Dragatsis, I.1
Dietrich, P.2
Zeitlin, S.3
-
8
-
-
0037150687
-
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease
-
Dunah AW, Jeong H, Griffin A, Kim YM, Standaert DG, Hersch SM, Mouradian MM, Young AB, Tanese N, Krainc D (2002) Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease. Science 296:2238-2243.
-
(2002)
Science
, vol.296
, pp. 2238-2243
-
-
Dunah, A.W.1
Jeong, H.2
Griffin, A.3
Kim, Y.M.4
Standaert, D.G.5
Hersch, S.M.6
Mouradian, M.M.7
Young, A.B.8
Tanese, N.9
Krainc, D.10
-
9
-
-
0032177037
-
Unraveling the central nervous system pathways underlying responses to leptin
-
Elmquist JK, Maratos-Flier E, Saper CB, Flier JS (1998) Unraveling the central nervous system pathways underlying responses to leptin. Nat Neurosci 1:445-450.
-
(1998)
Nat Neurosci
, vol.1
, pp. 445-450
-
-
Elmquist, J.K.1
Maratos-Flier, E.2
Saper, C.B.3
Flier, J.S.4
-
10
-
-
0030726894
-
Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin
-
Engelender S, Sharp AH, Colomer V, Tokito MK, Lanahan A, Worley P, Holzbaur EL, Ross CA (1997) Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin. Hum Mol Genet 6:2205-2212.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 2205-2212
-
-
Engelender, S.1
Sharp, A.H.2
Colomer, V.3
Tokito, M.K.4
Lanahan, A.5
Worley, P.6
Holzbaur, E.L.7
Ross, C.A.8
-
11
-
-
0036173770
-
Recruitment and activation of caspase-8 by the huntingtin-interacting protein Hip-1 and a novel partner Hippi
-
Gervais FG, Singaraja R, Xanthoudakis S, Gutekunst CA, Leavitt BR, Metzler M, Hackam AS, Tam J, Vaillancourt JP, Houtzager V, Rasper DM, Roy S, Hayden MR, Nicholson DW (2002) Recruitment and activation of caspase-8 by the huntingtin-interacting protein Hip-1 and a novel partner Hippi. Nat Cell Biol 4:95-105.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 95-105
-
-
Gervais, F.G.1
Singaraja, R.2
Xanthoudakis, S.3
Gutekunst, C.A.4
Leavitt, B.R.5
Metzler, M.6
Hackam, A.S.7
Tam, J.8
Vaillancourt, J.P.9
Houtzager, V.10
Rasper, D.M.11
Roy, S.12
Hayden, M.R.13
Nicholson, D.W.14
-
12
-
-
0032190391
-
The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): Comparison with huntingtin in rat and human
-
Gutekunst CA, Li SH, Yi H, Ferrante RJ, Li XJ, Hersch SM (1998) The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human. J Neurosci 18:7674-7686.
-
(1998)
J Neurosci
, vol.18
, pp. 7674-7686
-
-
Gutekunst, C.A.1
Li, S.H.2
Yi, H.3
Ferrante, R.J.4
Li, X.J.5
Hersch, S.M.6
-
13
-
-
0017645872
-
Impaired prolactin release in Huntington's chorea. Evidence for dopaminergic excess
-
Hayden MR, Vinik AI, Paul M, Beighton P (1977) Impaired prolactin release in Huntington's chorea. Evidence for dopaminergic excess. Lancet 2:423-426.
-
(1977)
Lancet
, vol.2
, pp. 423-426
-
-
Hayden, M.R.1
Vinik, A.I.2
Paul, M.3
Beighton, P.4
-
14
-
-
0036152343
-
Environmental enrichment slows disease progression in R6/2 Huntington's disease mice
-
Hockly E, Cordery PM, Woodman B, Mahal A, van Dellen A, Blakemore C, Lewis CM, Hannan AJ, Bates GP (2002) Environmental enrichment slows disease progression in R6/2 Huntington's disease mice. Ann Neurol 51:235-242.
-
(2002)
Ann Neurol
, vol.51
, pp. 235-242
-
-
Hockly, E.1
Cordery, P.M.2
Woodman, B.3
Mahal, A.4
Van Dellen, A.5
Blakemore, C.6
Lewis, C.M.7
Hannan, A.J.8
Bates, G.P.9
-
15
-
-
0033136692
-
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration
-
Hodgson JG, Agopyan N, Gutekunst CA, Leavitt BR, LePiane F, Singaraja R, Smith DJ, Bissada N, McCutcheon K, Nasir J, Jamot L, Li XJ, Stevens ME, Rosemond E, Roder JC, Phillips AG, Rubin EM, Hersch SM, Hayden MR (1999) A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration. Neuron 23:181-192.
-
(1999)
Neuron
, vol.23
, pp. 181-192
-
-
Hodgson, J.G.1
Agopyan, N.2
Gutekunst, C.A.3
Leavitt, B.R.4
LePiane, F.5
Singaraja, R.6
Smith, D.J.7
Bissada, N.8
McCutcheon, K.9
Nasir, J.10
Jamot, L.11
Li, X.J.12
Stevens, M.E.13
Rosemond, E.14
Roder, J.C.15
Phillips, A.G.16
Rubin, E.M.17
Hersch, S.M.18
Hayden, M.R.19
-
16
-
-
0033038418
-
Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
-
Kalra SP, Dube MG, Pu S, Xu B, Horvath TL, Kalra PS (1999) Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20:68-100.
-
(1999)
Endocr Rev
, vol.20
, pp. 68-100
-
-
Kalra, S.P.1
Dube, M.G.2
Pu, S.3
Xu, B.4
Horvath, T.L.5
Kalra, P.S.6
-
17
-
-
0032530365
-
Abnormal astrocyte development and neuronal death in mice lacking the epidermal growth factor receptor
-
Kornblum HI, Hussain R, Wiesen J, Miettinen P, Zurcher SD, Chow K, Derynck R, Werb Z (1998) Abnormal astrocyte development and neuronal death in mice lacking the epidermal growth factor receptor. J Neurosci Res 53:697-717.
-
(1998)
J Neurosci Res
, vol.53
, pp. 697-717
-
-
Kornblum, H.I.1
Hussain, R.2
Wiesen, J.3
Miettinen, P.4
Zurcher, S.D.5
Chow, K.6
Derynck, R.7
Werb, Z.8
-
18
-
-
0025281039
-
Atrophy of the hypothalamic lateral tuberal nucleus in Huntington's disease
-
Kremer HP, Roos RA, Dingjan G, Marani E, Bots GT (1990) Atrophy of the hypothalamic lateral tuberal nucleus in Huntington's disease. J Neuropathol Exp Neurol 49:371-382.
-
(1990)
J Neuropathol Exp Neurol
, vol.49
, pp. 371-382
-
-
Kremer, H.P.1
Roos, R.A.2
Dingjan, G.3
Marani, E.4
Bots, G.T.5
-
19
-
-
0026077859
-
The hypothalamic lateral tuberal nucleus and the characteristics of neuronal loss in Huntington's disease
-
Kremer HP, Roos RA, Dingjan GM, Bots GT, Bruyn GW, Hofman MA (1991) The hypothalamic lateral tuberal nucleus and the characteristics of neuronal loss in Huntington's disease. Neurosci Lett 132:101-104.
-
(1991)
Neurosci Lett
, vol.132
, pp. 101-104
-
-
Kremer, H.P.1
Roos, R.A.2
Dingjan, G.M.3
Bots, G.T.4
Bruyn, G.W.5
Hofman, M.A.6
-
20
-
-
0028803757
-
A huntingtin-associated protein enriched in brain with implications for pathology
-
Li XJ, Li SH, Sharp AH, Nucifora Jr FC, Schilling G, Lanahan A, Worley P, Snyder SH, Ross CA (1995) A huntingtin-associated protein enriched in brain with implications for pathology. Nature 378:398-402.
-
(1995)
Nature
, vol.378
, pp. 398-402
-
-
Li, X.J.1
Li, S.H.2
Sharp, A.H.3
Nucifora F.C., Jr.4
Schilling, G.5
Lanahan, A.6
Worley, P.7
Snyder, S.H.8
Ross, C.A.9
-
21
-
-
0029899868
-
Huntingtin-associated protein (HAP1): Discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase
-
Li XJ, Sharp AH, Li SH, Dawson TM, Snyder SH, Ross CA (1996) Huntingtin-associated protein (HAP1): discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase. Proc Natl Acad Sci USA 93:4839-4844.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 4839-4844
-
-
Li, X.J.1
Sharp, A.H.2
Li, S.H.3
Dawson, T.M.4
Snyder, S.H.5
Ross, C.A.6
-
22
-
-
0032519646
-
Interaction of huntingtin-associated protein with dynactin P150Glued
-
Li SH, Gutekunst CA, Hersch SM, Li XJ (1998a) Interaction of huntingtin-associated protein with dynactin P150Glued. J Neurosci 18:1261-1269.
-
(1998)
J Neurosci
, vol.18
, pp. 1261-1269
-
-
Li, S.H.1
Gutekunst, C.A.2
Hersch, S.M.3
Li, X.J.4
-
23
-
-
0032563107
-
A human HAP1 homologue. Cloning, expression, and interaction with huntingtin
-
Li SH, Hosseini SH, Gutekunst CA, Hersch SM, Ferrante RJ, Li XJ (1998b) A human HAP1 homologue. Cloning, expression, and interaction with huntingtin. J Biol Chem 273:19220-19227.
-
(1998)
J Biol Chem
, vol.273
, pp. 19220-19227
-
-
Li, S.H.1
Hosseini, S.H.2
Gutekunst, C.A.3
Hersch, S.M.4
Ferrante, R.J.5
Li, X.J.6
-
24
-
-
0033168302
-
Cellular defects and altered gene expression in PC12 cells stably expressing mutant huntingtin
-
Li SH, Cheng AL, Li H, Li XJ (1999) Cellular defects and altered gene expression in PC12 cells stably expressing mutant huntingtin. J Neurosci 19:5159-5172.
-
(1999)
J Neurosci
, vol.19
, pp. 5159-5172
-
-
Li, S.H.1
Cheng, A.L.2
Li, H.3
Li, X.J.4
-
25
-
-
0033848272
-
Expression of huntingtin-associated protein-1 in neuronal cells implicates a role in neuritic growth
-
Li SH, Li H, Torre ER, Li XJ (2000a) Expression of huntingtin-associated protein-1 in neuronal cells implicates a role in neuritic growth. Mol Cell Neurosci 16:168-183.
-
(2000)
Mol Cell Neurosci
, vol.16
, pp. 168-183
-
-
Li, S.H.1
Li, H.2
Torre, E.R.3
Li, X.J.4
-
26
-
-
0034426013
-
Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity
-
Li H, Li SH, Johnston H, Shelbourne PF, Li XJ (2000b) Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity. Nat Genet 25:385-389.
-
(2000)
Nat Genet
, vol.25
, pp. 385-389
-
-
Li, H.1
Li, S.H.2
Johnston, H.3
Shelbourne, P.F.4
Li, X.J.5
-
27
-
-
0036173896
-
Interaction of huntington disease protein with transcriptional activator sp1
-
Li SH, Cheng AL, Zhou H, Lam S, Rao M, Li H, Li XJ (2002a) Interaction of huntington disease protein with transcriptional activator sp1. Mol Cell Biol 22:1277-1287.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1277-1287
-
-
Li, S.H.1
Cheng, A.L.2
Zhou, H.3
Lam, S.4
Rao, M.5
Li, H.6
Li, X.J.7
-
28
-
-
0037008677
-
Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking
-
Li Y, Chin LS, Levey AI, Li L (2002b) Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking. J Biol Chem 277:28212-28221.
-
(2002)
J Biol Chem
, vol.277
, pp. 28212-28221
-
-
Li, Y.1
Chin, L.S.2
Levey, A.I.3
Li, L.4
-
29
-
-
0034647947
-
Dopamine and serotonin VMN release is related to feeding status in obese and lean Zucker rats
-
Meguid MM, Fetissov SO, Blaha V, Yang ZJ (2000) Dopamine and serotonin VMN release is related to feeding status in obese and lean Zucker rats. NeuroReport 11:2069-2072.
-
(2000)
NeuroReport
, vol.11
, pp. 2069-2072
-
-
Meguid, M.M.1
Fetissov, S.O.2
Blaha, V.3
Yang, Z.J.4
-
30
-
-
0035914402
-
HIP1 functions in clathrin-mediated endocytosis through binding to dathrin and adaptor protein 2
-
Metzler M, Legendre-Guillemin V, Gan L, Chopra V, Kwok A, McPherson PS, Hayden MR (2001) HIP1 functions in clathrin-mediated endocytosis through binding to dathrin and adaptor protein 2. J Biol Chem 276:39271-39276.
-
(2001)
J Biol Chem
, vol.276
, pp. 39271-39276
-
-
Metzler, M.1
Legendre-Guillemin, V.2
Gan, L.3
Chopra, V.4
Kwok, A.5
McPherson, P.S.6
Hayden, M.R.7
-
31
-
-
15444354778
-
Gene structure and map location of the murine homolog of the Huntington-associated protein, Hap 1
-
Nasir J, Duan K, Nichol K, Engelender S, Ashworth R, Colomer V, Thomas S, Disteche CM, Hayden MR, Ross CA (1998) Gene structure and map location of the murine homolog of the Huntington-associated protein, Hap 1. Mamm Genome 9:565-570.
-
(1998)
Mamm Genome
, vol.9
, pp. 565-570
-
-
Nasir, J.1
Duan, K.2
Nichol, K.3
Engelender, S.4
Ashworth, R.5
Colomer, V.6
Thomas, S.7
Disteche, C.M.8
Hayden, M.R.9
Ross, C.A.10
-
32
-
-
0035802115
-
Role of PI 3-kinase, Akt and Bcl-2-related proteins in sustaining the survival of neurotrophic factor-independent adult sympathetic neurons
-
Orike N, Middleton G, Borthwick E, Buchman V, Cowen T, Davies AM (2001) Role of PI 3-kinase, Akt and Bcl-2-related proteins in sustaining the survival of neurotrophic factor-independent adult sympathetic neurons. J Cell Biol 154:995-1005.
-
(2001)
J Cell Biol
, vol.154
, pp. 995-1005
-
-
Orike, N.1
Middleton, G.2
Borthwick, E.3
Buchman, V.4
Cowen, T.5
Davies, A.M.6
-
33
-
-
0031814172
-
The expression of huntingtin-associated protein (HAP1) mRNA in developing, adult and ageing rat CNS: Implications for Huntington's disease neuropathology
-
Page KJ, Potter L, Aronni S, Everitt BJ, Dunnett SB (1998) The expression of huntingtin-associated protein (HAP1) mRNA in developing, adult and ageing rat CNS: implications for Huntington's disease neuropathology. Eur J Neurosci 10:1835-1845.
-
(1998)
Eur J Neurosci
, vol.10
, pp. 1835-1845
-
-
Page, K.J.1
Potter, L.2
Aronni, S.3
Everitt, B.J.4
Dunnett, S.B.5
-
34
-
-
0035940286
-
Development of pro-TRH gene expression in primary cultures of fetal hypothalamic cells
-
Perez-Martinez L, Charli JL, Joseph-Bravo P (2001) Development of pro-TRH gene expression in primary cultures of fetal hypothalamic cells. Brain Res Dev Brain Res 130:73-81.
-
(2001)
Brain Res Dev Brain Res
, vol.130
, pp. 73-81
-
-
Perez-Martinez, L.1
Charli, J.L.2
Joseph-Bravo, P.3
-
35
-
-
0033965329
-
Higher sedentary energy expenditure in patients with Huntington's disease
-
Pratley RE, Salbe AD, Ravussin E, Caviness JN (2000) Higher sedentary energy expenditure in patients with Huntington's disease. Ann Neurol 47:64-70.
-
(2000)
Ann Neurol
, vol.47
, pp. 64-70
-
-
Pratley, R.E.1
Salbe, A.D.2
Ravussin, E.3
Caviness, J.N.4
-
36
-
-
0034780505
-
Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors
-
Rao DS, Chang JC, Kumar PD, Mizukami I, Smithson GM, Bradley SV, Parlow AF, Ross TS (2001) Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors. Mol Cell Biol 21:7796-7806.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7796-7806
-
-
Rao, D.S.1
Chang, J.C.2
Kumar, P.D.3
Mizukami, I.4
Smithson, G.M.5
Bradley, S.V.6
Parlow, A.F.7
Ross, T.S.8
-
37
-
-
17344367977
-
Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA
-
Reddy PH, Williams M, Charles V, Garrett L, Pike-Buchanan L, Whetsell Jr WO, Miller G, Tagle DA (1998) Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA. Nat Genet 20:198-202.
-
(1998)
Nat Genet
, vol.20
, pp. 198-202
-
-
Reddy, P.H.1
Williams, M.2
Charles, V.3
Garrett, L.4
Pike-Buchanan, L.5
Whetsell W.O., Jr.6
Miller, G.7
Tagle, D.A.8
-
38
-
-
0019796509
-
Body weight and dietary factors in Huntington's disease patients compared with matched controls
-
Sanberg PR, Fibiger HC, Mark RF (1981) Body weight and dietary factors in Huntington's disease patients compared with matched controls. Med J Aust 1:407-409.
-
(1981)
Med J Aust
, vol.1
, pp. 407-409
-
-
Sanberg, P.R.1
Fibiger, H.C.2
Mark, R.F.3
-
39
-
-
0037461730
-
Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders
-
Sanchez I, Mahlke C, Yuan J (2003) Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders. Nature 421:373-379.
-
(2003)
Nature
, vol.421
, pp. 373-379
-
-
Sanchez, I.1
Mahlke, C.2
Yuan, J.3
-
40
-
-
0033054555
-
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin
-
Schilling G, Becher MW, Sharp AH, Jinnah HA, Duan K, Kotzuk JA, Slunt HH, Ratovitski T, Cooper JK, Jenkins NA, Copeland NG, Price DL, Ross CA, Borchelt DR (1999) Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin. Hum Mol Genet 8:397-407.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 397-407
-
-
Schilling, G.1
Becher, M.W.2
Sharp, A.H.3
Jinnah, H.A.4
Duan, K.5
Kotzuk, J.A.6
Slunt, H.H.7
Ratovitski, T.8
Cooper, J.K.9
Jenkins, N.A.10
Copeland, N.G.11
Price, D.L.12
Ross, C.A.13
Borchelt, D.R.14
-
41
-
-
0034611732
-
Central nervous system control of food intake
-
Schwartz MW, Woods SC, Porte Jr D, Seeley RJ, Baskin DG (2000) Central nervous system control of food intake. Nature 404:661-671.
-
(2000)
Nature
, vol.404
, pp. 661-671
-
-
Schwartz, M.W.1
Woods, S.C.2
Porte D., Jr.3
Seeley, R.J.4
Baskin, D.G.5
-
42
-
-
0032472938
-
A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor
-
Sibilia M, Steinbach JP, Stingl L, Aguzzi A, Wagner EF (1998) A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor. EMBO J 17:719-731.
-
(1998)
EMBO J
, vol.17
, pp. 719-731
-
-
Sibilia, M.1
Steinbach, J.P.2
Stingl, L.3
Aguzzi, A.4
Wagner, E.F.5
-
43
-
-
0037155198
-
Expression of full-length polyglutamine-expanded huntingtin disrupts growth factor receptor signaling in rat pheochromocytoma (PC12) cells
-
Song C, Perides G, Liu YF (2002) Expression of full-length polyglutamine-expanded huntingtin disrupts growth factor receptor signaling in rat pheochromocytoma (PC12) cells. J Biol Chem 277:6703-6707.
-
(2002)
J Biol Chem
, vol.277
, pp. 6703-6707
-
-
Song, C.1
Perides, G.2
Liu, Y.F.3
-
44
-
-
0022395922
-
Neuropathological classification of Huntington's disease
-
Vonsattel JP, Myers RH, Stevens TJ, Ferrante RJ, Bird ED, Richardson Jr EP (1985) Neuropathological classification of Huntington's disease. J Neuropathol Exp Neurol 44:559-577.
-
(1985)
J Neuropathol Exp Neurol
, vol.44
, pp. 559-577
-
-
Vonsattel, J.P.1
Myers, R.H.2
Stevens, T.J.3
Ferrante, R.J.4
Bird, E.D.5
Richardson E.P., Jr.6
-
45
-
-
0036787904
-
Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival
-
Wang Y, Pennock S, Chen X, Wang Z (2002) Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival. Mol Cell Biol 22:7279-7290.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7279-7290
-
-
Wang, Y.1
Pennock, S.2
Chen, X.3
Wang, Z.4
-
47
-
-
0037444445
-
Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease
-
Yu Z-X, Li S-H, Evans J, Pillarisetti A, Li H, Li X-J (2003) Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease. J Neurosci 23:2193-2202
-
(2003)
J Neurosci
, vol.23
, pp. 2193-2202
-
-
Yu, Z.-X.1
Li, S.-H.2
Evans, J.3
Pillarisetti, A.4
Li, H.5
Li, X.-J.6
-
48
-
-
0037075624
-
Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease
-
Zeron MM, Hansson O, Chen N, Wellington CL, Leavitt BR, Brundin P, Hayden MR, Raymond LA (2002) Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease. Neuron 33:849-860.
-
(2002)
Neuron
, vol.33
, pp. 849-860
-
-
Zeron, M.M.1
Hansson, O.2
Chen, N.3
Wellington, C.L.4
Leavitt, B.R.5
Brundin, P.6
Hayden, M.R.7
Raymond, L.A.8
-
49
-
-
0034094873
-
Glutamine repeats and neurodegeneration
-
Zoghbi HY, Orr HT (2000) Glutamine repeats and neurodegeneration. Annu Rev Neurosci 23:217-247.
-
(2000)
Annu Rev Neurosci
, vol.23
, pp. 217-247
-
-
Zoghbi, H.Y.1
Orr, H.T.2
-
50
-
-
0035919701
-
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
-
Zuccato C, Ciammola A, Rigamonti D, Leavitt BR, Goffredo D, Conti L, MacDonald ME, Friedlander RM, Silani V, Hayden MR, Timmusk T, Sipione S, Cattaneo E (2001) Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease. Science 293:493-498.
-
(2001)
Science
, vol.293
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
Leavitt, B.R.4
Goffredo, D.5
Conti, L.6
MacDonald, M.E.7
Friedlander, R.M.8
Silani, V.9
Hayden, M.R.10
Timmusk, T.11
Sipione, S.12
Cattaneo, E.13
|