메뉴 건너뛰기




Volumn 34, Issue 3, 2011, Pages 261-272

Evidence for neuroinflammatory and microglial changes in the cerebral response to sleep loss

Author keywords

CD11b; Cytokines; Microglia; Neuroinflammation; Real time polymerase chain reaction

Indexed keywords

BENZODIAZEPINE RECEPTOR; CD11B ANTIGEN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MINOCYCLINE; PROTEIN C FOS; TUMOR NECROSIS FACTOR ALPHA;

EID: 79953645895     PISSN: 01618105     EISSN: 15509109     Source Type: Journal    
DOI: 10.1093/sleep/34.3.261     Document Type: Article
Times cited : (98)

References (86)
  • 2
    • 60549090569 scopus 로고    scopus 로고
    • How (and why) the immune system makes us sleep
    • Imeri L, Opp MR. How (and why) the immune system makes us sleep. Nat Rev Neurosci 2009;10:199-210.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 199-210
    • Imeri, L.1    Opp, M.R.2
  • 3
  • 4
    • 34248645632 scopus 로고    scopus 로고
    • The metabolic consequences of sleep deprivation
    • DOI 10.1016/j.smrv.2007.01.002, PII S1087079207000202
    • Knutson KL, Spiegel K, Penev P, Van Cauter E. The metabolic consequences of sleep deprivation. Sleep Med Rev 2007;11:163-78. (Pubitemid 46778995)
    • (2007) Sleep Medicine Reviews , vol.11 , Issue.3 , pp. 163-178
    • Knutson, K.L.1    Spiegel, K.2    Penev, P.3    Van Cauter, E.4
  • 5
    • 49749142997 scopus 로고    scopus 로고
    • Sleep loss activates cellular inflammatory signaling
    • Irwin MR, Wang M, Ribeiro D, et al. Sleep loss activates cellular inflammatory signaling. Biol Psychiatry 2008;64:538-40.
    • (2008) Biol Psychiatry , vol.64 , pp. 538-540
    • Irwin, M.R.1    Wang, M.2    Ribeiro, D.3
  • 6
    • 58149188208 scopus 로고    scopus 로고
    • Relationship between inflammation and cognitive function in obstructive sleep apnea
    • Haensel A, Bardwell WA, Mills PJ, et al. Relationship between inflammation and cognitive function in obstructive sleep apnea. Sleep Breath 2009;13:35-41
    • (2009) Sleep Breath , vol.13 , pp. 35-41
    • Haensel, A.1    Bardwell, W.A.2    Mills, P.J.3
  • 7
    • 34548514172 scopus 로고    scopus 로고
    • Elevated inflammatory markers in response to prolonged sleep restriction are associated with increased pain experience in healthy volunteers
    • Haack M, Sanchez E, Mullington JM. Elevated inflammatory markers in response to prolonged sleep restriction are associated with increased pain experience in healthy volunteers. Sleep 2007;30:1145-52. (Pubitemid 47378957)
    • (2007) Sleep , vol.30 , Issue.9 , pp. 1145-1152
    • Haack, M.1    Sanchez, E.2    Mullington, J.M.3
  • 8
    • 34848823108 scopus 로고    scopus 로고
    • The effects of 40 hours of total sleep deprivation on inflammatory markers in healthy young adults
    • DOI 10.1016/j.bbi.2007.04.003, PII S0889159107000864
    • Frey DJ, Fleshner M, Wright KP Jr. The effects of 40 hours of total sleep deprivation on inflammatory markers in healthy young adults. Brain Behav Immun 2007;21:1050-7. (Pubitemid 47496127)
    • (2007) Brain, Behavior, and Immunity , vol.21 , Issue.8 , pp. 1050-1057
    • Frey, D.J.1    Fleshner, M.2    Wright Jr., K.P.3
  • 9
    • 33748796064 scopus 로고    scopus 로고
    • Sleep deprivation and activation of morning levels of cellular and genomic markers of inflammation
    • Irwin MR, Wang M, Campomayor CO, Collado-Hidalgo A, Cole S. Sleep deprivation and activation of morning levels of cellular and genomic markers of inflammation. Arch Intern Med 2006;166:1756-62.
    • (2006) Arch Intern Med , vol.166 , pp. 1756-1762
    • Irwin, M.R.1    Wang, M.2    Campomayor, C.O.3    Collado-Hidalgo, A.4    Cole, S.5
  • 10
    • 84887212362 scopus 로고    scopus 로고
    • Sleep restriction increases the risk of developing cardiovascular diseases by augmenting proinflammatory responses through IL-17 and CRP
    • van Leeuwen WM, Lehto M, Karisola P, et al. Sleep restriction increases the risk of developing cardiovascular diseases by augmenting proinflammatory responses through IL-17 and CRP. PLoS One 2009;4:e4589.
    • (2009) PLoS One , vol.4
    • Van Leeuwen, W.M.1    Lehto, M.2    Karisola, P.3
  • 11
    • 0036355972 scopus 로고    scopus 로고
    • Brain-immune interactions in sleep
    • Marshall L, Born J. Brain-immune interactions in sleep. Int Rev Neurobiol 2002;52:93-131.
    • (2002) Int Rev Neurobiol , vol.52 , pp. 93-131
    • Marshall, L.1    Born, J.2
  • 12
    • 58949088982 scopus 로고    scopus 로고
    • The role of cytokines in sleep regulation
    • Krueger JM. The role of cytokines in sleep regulation. Curr Pharm Des 2008;14:3408-16.
    • (2008) Curr Pharm Des , vol.14 , pp. 3408-3416
    • Krueger, J.M.1
  • 13
    • 0001273241 scopus 로고    scopus 로고
    • Basic mechanisms of sleep-wake states
    • Kryger MH, Roth T, Dement WC, eds. 3rd ed. Philadelphia: WB Saunders
    • Jones BE. Basic mechanisms of sleep-wake states. In: Kryger MH, Roth T, Dement WC, eds. Principles and practice of sleep medicine. 3rd ed. Philadelphia: WB Saunders, 2000:134-54.
    • (2000) Principles and Practice of Sleep Medicine , pp. 134-154
    • Jones, B.E.1
  • 14
    • 70349267594 scopus 로고    scopus 로고
    • Endogenous nonneuronal modulators of synaptic transmission control cortical slow oscillations in vivo
    • Fellin T, Halassa MM, Terunuma M, et al. Endogenous nonneuronal modulators of synaptic transmission control cortical slow oscillations in vivo. Proc Natl Acad Sci U S A 2009;106:15037-42.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 15037-15042
    • Fellin, T.1    Halassa, M.M.2    Terunuma, M.3
  • 15
    • 58549112040 scopus 로고    scopus 로고
    • Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss
    • Halassa MM, Florian C, Fellin T, et al. Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss. Neuron 2009;61:213-9.
    • (2009) Neuron , vol.61 , pp. 213-219
    • Halassa, M.M.1    Florian, C.2    Fellin, T.3
  • 16
    • 61449224570 scopus 로고    scopus 로고
    • Microglia: Gatekeepers of central nervous system immunology
    • Tambuyzer BR, Ponsaerts P, Nouwen EJ. Microglia: gatekeepers of central nervous system immunology. J Leukoc Biol 2008;352-70:352-70.
    • (2008) J Leukoc Biol , vol.352 , Issue.70 , pp. 352-370
    • Tambuyzer, B.R.1    Ponsaerts, P.2    Nouwen, E.J.3
  • 17
    • 0034882399 scopus 로고    scopus 로고
    • Spinal cord glia: New players in pain
    • DOI 10.1016/S0304-3959(01)00359-1, PII S0304395901003591
    • Watkins LR, Milligan ED, Maier SF. Spinal cord glia: new players in pain. Pain 2001;93:201-5. (Pubitemid 32763176)
    • (2001) Pain , vol.93 , Issue.3 , pp. 201-205
    • Watkins, L.R.1    Milligan, E.D.2    Maier, S.F.3
  • 18
    • 54249124166 scopus 로고    scopus 로고
    • Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system
    • Dilger RN, Johnson RW. Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system. J Leukoc Biol 2008;84:932-9.
    • (2008) J Leukoc Biol , vol.84 , pp. 932-939
    • Dilger, R.N.1    Johnson, R.W.2
  • 19
    • 13244281729 scopus 로고    scopus 로고
    • Immune regulation of central nervous system functions: From sickness responses to pathological pain
    • DOI 10.1111/j.1365-2796.2004.01443.x
    • Watkins LR, Maier SF. Immune regulation of central nervous system functions: from sickness responses to pathological pain. J Intern Med 2005;257:139-55. (Pubitemid 40193964)
    • (2005) Journal of Internal Medicine , vol.257 , Issue.2 , pp. 139-155
    • Watkins, L.R.1    Maier, S.F.2
  • 21
    • 57549088119 scopus 로고    scopus 로고
    • Minocycline and neurodegenerative diseases
    • Kim HS, Suh YH. Minocycline and neurodegenerative diseases. Behav Brain Res 2009;196:168-79.
    • (2009) Behav Brain Res , vol.196 , pp. 168-179
    • Kim, H.S.1    Suh, Y.H.2
  • 22
    • 0021068290 scopus 로고
    • Effects of antibiotics, minocycline and ampicillin, on human sleep
    • Nonaka K, Nakazawa Y, Kotorii T. Effects of antibiotics, minocycline and ampicillin, on human sleep. Brain Res 1983;288:253-9. (Pubitemid 14212714)
    • (1983) Brain Research , vol.288 , Issue.1-2 , pp. 253-259
    • Nonaka, K.1    Nakazawa, Y.2    Kotorii, T.3
  • 23
    • 0030469564 scopus 로고    scopus 로고
    • Strain differences in the somnogenic effects of interferon inducers in mice
    • Toth LA. Strain differences in the somnogenic effects of interferon inducers in mice. J Interferon Cytokine Res 1996;16:1065-72. (Pubitemid 26427040)
    • (1996) Journal of Interferon and Cytokine Research , vol.16 , Issue.12 , pp. 1065-1072
    • Toth, L.A.1
  • 25
    • 0034624293 scopus 로고    scopus 로고
    • Gene expression in the brain across the sleep-waking cycle
    • Cirelli C, Tononi G. Gene expression in the brain across the sleep-waking cycle. Brain Res 2000;885:303-21.
    • (2000) Brain Res , vol.885 , pp. 303-321
    • Cirelli, C.1    Tononi, G.2
  • 26
    • 0037979161 scopus 로고    scopus 로고
    • Sleep deprivation inhibits expression of NADPH-d and NOS while activating microglia and astroglia in the rat hippocampus
    • Hsu JC, Lee YS, Chang CN, Chuang HL, Ling EA, Lan CT. Sleep deprivation inhibits expression of NADPH-d and NOS while activating microglia and astroglia in the rat hippocampus. Cells Tissues Organs 2003;173:242-54.
    • (2003) Cells Tissues Organs , vol.173 , pp. 242-254
    • Hsu, J.C.1    Lee, Y.S.2    Chang, C.N.3    Chuang, H.L.4    Ling, E.A.5    Lan, C.T.6
  • 27
    • 67650966680 scopus 로고    scopus 로고
    • Microglial physiology: Unique stimuli, specialized responses
    • Ransohoff RM, Perry VH. Microglial physiology: unique stimuli, specialized responses. Annu Rev Immunol 2009;27:119-45.
    • (2009) Annu Rev Immunol , vol.27 , pp. 119-145
    • Ransohoff, R.M.1    Perry, V.H.2
  • 28
    • 73049110767 scopus 로고    scopus 로고
    • The multifaceted profile of activated microglia
    • Lynch MA. The multifaceted profile of activated microglia. Mol Neurobiol 2009;40:139-56.
    • (2009) Mol Neurobiol , vol.40 , pp. 139-156
    • Lynch, M.A.1
  • 29
    • 60149097714 scopus 로고    scopus 로고
    • Differential microglial activation between acute stress and lipopolysaccharide treatment
    • Sugama S, Takenouchi T, Fujita M, Conti B, Hashimoto M. Differential microglial activation between acute stress and lipopolysaccharide treatment. J Neuroimmunol 2008;207:24-31.
    • (2008) J Neuroimmunol , vol.207 , pp. 24-31
    • Sugama, S.1    Takenouchi, T.2    Fujita, M.3    Conti, B.4    Hashimoto, M.5
  • 30
    • 0035800589 scopus 로고    scopus 로고
    • Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum
    • He Y, Appel S, Le W. Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum. Brain Res 2001;909:187-93.
    • (2001) Brain Res , vol.909 , pp. 187-193
    • He, Y.1    Appel, S.2    Le, W.3
  • 32
    • 62749201498 scopus 로고    scopus 로고
    • Genetic variation and population substructure in outbred CD-1 mice: Implications for genome-wide association studies
    • Aldinger KA, Sokoloff G, Rosenberg DM, Palmer AA, Millen KJ. Genetic variation and population substructure in outbred CD-1 mice: implications for genome-wide association studies. PLoS ONE 2009;4:e4729.
    • (2009) PLoS ONE , vol.4
    • Aldinger, K.A.1    Sokoloff, G.2    Rosenberg, D.M.3    Palmer, A.A.4    Millen, K.J.5
  • 33
    • 0003633755 scopus 로고    scopus 로고
    • Institute of Laboratory Animal Resources CoLS, National Research Council. Washington, DC: National Academy Press
    • Institute of Laboratory Animal Resources CoLS, National Research Council. Guide for Care and Use of Laboratory Animals. Washington, DC: National Academy Press, 1996.
    • (1996) Guide for Care and Use of Laboratory Animals
  • 34
    • 49049110545 scopus 로고    scopus 로고
    • Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains
    • Wisor JP, Pasumarthi RK, Gerashchenko D, et al. Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains. J Neurosci 2008;28:7193-201.
    • (2008) J Neurosci , vol.28 , pp. 7193-7201
    • Wisor, J.P.1    Pasumarthi, R.K.2    Gerashchenko, D.3
  • 35
    • 0347885320 scopus 로고    scopus 로고
    • A role for cryptochromes in sleep regulation
    • Wisor JP, O'Hara BF, Terao A, et al. A role for cryptochromes in sleep regulation. BMC Neurosci 2002;3:20.
    • (2002) BMC Neurosci , vol.3 , pp. 20
    • Wisor, J.P.1    O'Hara, B.F.2    Terao, A.3
  • 36
    • 0035871645 scopus 로고    scopus 로고
    • The homeostatic regulation of sleep need is under genetic control
    • Franken P, Chollet D, Tafti M. The homeostatic regulation of sleep need is under genetic control. J Neurosci 2001;21:2610-21. (Pubitemid 32298203)
    • (2001) Journal of Neuroscience , vol.21 , Issue.8 , pp. 2610-2621
    • Franken, P.1    Chollet, D.2    Tafti, M.3
  • 37
    • 0033983933 scopus 로고    scopus 로고
    • Effects of sleep deprivation on sleep and sleep EEG in three mouse strains: Empirical data and simulations
    • DOI 10.1016/S0006-8993(99)02248-9, PII S0006899399022489
    • Huber R, Deboer T, Tobler I. Effects of sleep deprivation on sleep and sleep EEG in three mouse strains: empirical data and simulations. Brain Res 2000;857:8-19. (Pubitemid 30107786)
    • (2000) Brain Research , vol.857 , Issue.1-2 , pp. 8-19
    • Huber, R.1    Deboer, T.2    Tobler, I.3
  • 38
    • 44949231424 scopus 로고    scopus 로고
    • T method
    • DOI 10.1038/nprot.2008.73, PII NPROT.2008.73
    • Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 2008;3:1101-8. (Pubitemid 351818697)
    • (2008) Nature Protocols , vol.3 , Issue.6 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 39
    • 36148966152 scopus 로고    scopus 로고
    • Neural-immune interactions in disorders of sleep-wakefulness organization
    • DOI 10.1016/j.tins.2007.09.004, PII S0166223607002603
    • Bentivoglio M, Kristensson K. Neural-immune interactions in disorders of sleep-wakefulness organization. Trends Neurosci 2007;30:645-52. (Pubitemid 350110483)
    • (2007) Trends in Neurosciences , vol.30 , Issue.12 , pp. 645-652
    • Bentivoglio, M.1    Kristensson, K.2
  • 40
    • 36249012543 scopus 로고    scopus 로고
    • 1- integrin, and Kv1.3 channel expression
    • DOI 10.1111/j.1471-4159.2007.04889.x
    • Nutile-McMenemy N, Elfenbein A, Deleo JA. Minocycline decreases in vitro microglial motility, beta1-integrin, and Kv1.3 channel expression. J Neurochem 2007;103:2035-46. (Pubitemid 350126620)
    • (2007) Journal of Neurochemistry , vol.103 , Issue.5 , pp. 2035-2046
    • Nutile-McMenemy, N.1    Elfenbein, A.2    DeLeo, J.A.3
  • 41
    • 77954347484 scopus 로고    scopus 로고
    • Spinal glial TLR4-mediated nociception and production of prostaglandin E and TNF
    • Saito O, Svensson CI, Buczynski MW, et al. Spinal glial TLR4-mediated nociception and production of prostaglandin E and TNF. Br J Pharmacol 2010;160:1754-64.
    • (2010) Br J Pharmacol , vol.160 , pp. 1754-1764
    • Saito, O.1    Svensson, C.I.2    Buczynski, M.W.3
  • 42
    • 77955096497 scopus 로고    scopus 로고
    • Release of prostaglandin E2 and nitric oxide from spinal microglia is dependent on activation of p38 mitogen-activated protein kinase
    • Matsui T, Svensson CI, Hirata Y, Mizobata K, Hua XY, Yaksh TL. Release of prostaglandin E2 and nitric oxide from spinal microglia is dependent on activation of p38 mitogen-activated protein kinase. Anesth Analg 2010 111;554-60.
    • (2010) Anesth Analg , vol.111 , pp. 554-560
    • Matsui, T.1    Svensson, C.I.2    Hirata, Y.3    Mizobata, K.4    Hua, X.Y.5    Yaksh, T.L.6
  • 43
    • 0007305478 scopus 로고    scopus 로고
    • IL1β knockout mice lack the TNFα response to sleep deprivation but have normal sleep and sleep recovery
    • Veasey SC, Mackiewicz M, Fenik P, Ro M, Ogilvie MD, Pack AI. IL1β knockout mice lack the TNFα response to sleep deprivation but have normal sleep and sleep recovery. Soc Neur Abs 1997;23:792.
    • (1997) Soc Neur Abs , vol.23 , pp. 792
    • Veasey, S.C.1    Mackiewicz, M.2    Fenik, P.3    Ro, M.4    Ogilvie, M.D.5    Pack, A.I.6
  • 45
    • 0027391277 scopus 로고
    • Immediate early gene expression in brain during sleep deprivation: Preliminary observations
    • O'Hara BF, Young KA, Watson FL, Heller HC, Kilduff TS. Immediate early gene expression in brain during sleep deprivation: preliminary observations. Sleep 1993;16:1-7. (Pubitemid 23024689)
    • (1993) Sleep , vol.16 , Issue.1 , pp. 1-7
    • O'Hara, B.F.1    Young, K.A.2    Watson, F.L.3    Heller, H.C.4    Kilduff, T.S.5
  • 46
    • 0028301115 scopus 로고
    • Immediate-early genes in spontaneous wakefulness and sleep: Expression of c-fos and NGFI-A mRNA and protein
    • Pompeiano M, Cirelli C, Tononi G. Immediate-early genes in spontaneous wakefulness and sleep: expression of c-fos and NGFI-A mRNA and protein. J Sleep Res 1994;3:80-96. (Pubitemid 24173498)
    • (1994) Journal of Sleep Research , vol.3 , Issue.2 , pp. 80-96
    • Pompeiano, M.1    Cirelli, C.2    Tononi, G.3
  • 47
    • 0029910282 scopus 로고    scopus 로고
    • Neuronal gene expression in the waking state: A role for the locus coeruleus
    • DOI 10.1126/science.274.5290.1211
    • Cirelli C, Pompeiano M, Tononi G. Neuronal gene expression in the waking state: a role for the locus coeruleus. Science 1996;274:1211-5. (Pubitemid 26389291)
    • (1996) Science , vol.274 , Issue.5290 , pp. 1211-1215
    • Cirelli, C.1    Pompeiano, M.2    Tononi, G.3
  • 49
    • 70349729991 scopus 로고    scopus 로고
    • Protection against chronic hypoperfusion- induced retinal neurodegeneration by PARP inhibition via activation of PI-3-kinase Akt pathway and suppression of JNK and p38 MAP kinases
    • Mester L, Szabo A, Atlasz T, et al. Protection against chronic hypoperfusion- induced retinal neurodegeneration by PARP inhibition via activation of PI-3-kinase Akt pathway and suppression of JNK and p38 MAP kinases. Neurotox Res 2009;16:68-76.
    • (2009) Neurotox Res , vol.16 , pp. 68-76
    • Mester, L.1    Szabo, A.2    Atlasz, T.3
  • 50
    • 70349736192 scopus 로고    scopus 로고
    • Dual modulation of ERK1/2 and p38 MAP kinase activities induced by minocycline reverses the neurotoxic effects of the prion protein fragment 90-231
    • Corsaro A, Thellung S, Chiovitti K, et al. Dual modulation of ERK1/2 and p38 MAP kinase activities induced by minocycline reverses the neurotoxic effects of the prion protein fragment 90-231. Neurotox Res 2009;15:138-54.
    • (2009) Neurotox Res , vol.15 , pp. 138-154
    • Corsaro, A.1    Thellung, S.2    Chiovitti, K.3
  • 51
    • 0033966193 scopus 로고    scopus 로고
    • Calmodulin-dependent activation of p38 and p42/44 mitogen-activated protein kinases contributes to c-fos expression by calcium in PC12 cells: Modulation by nitric oxide
    • DOI 10.1016/S0169-328X(99)00280-6, PII S0169328X99002806
    • Lee SA, Park JK, Kang EK, Bae HR, Bae KW, Park HT. Calmodulin-dependent activation of p38 and p42/44 mitogen-activated protein kinases contributes to c-fos expression by calcium in PC12 cells: modulation by nitric oxide. Brain Res Mol Brain Res 2000;75:16-24. (Pubitemid 30058322)
    • (2000) Molecular Brain Research , vol.75 , Issue.1 , pp. 16-24
    • Lee, S.A.1    Park, J.K.2    Kang, E.K.3    Bae, H.R.4    Bae, K.W.5    Park, H.T.6
  • 52
    • 33748092874 scopus 로고    scopus 로고
    • Cellular consequences of sleep deprivation in the brain
    • DOI 10.1016/j.smrv.2006.04.001, PII S1087079206000293
    • Cirelli C. Cellular consequences of sleep deprivation in the brain. Sleep Med Rev 2006;10:307-21. (Pubitemid 44307714)
    • (2006) Sleep Medicine Reviews , vol.10 , Issue.5 , pp. 307-321
    • Cirelli, C.1
  • 53
    • 2942590400 scopus 로고    scopus 로고
    • Locus ceruleus control of state-dependent gene expression
    • DOI 10.1523/JNEUROSCI.0949-04.2004
    • Cirelli C, Tononi G. Locus ceruleus control of state-dependent gene expression. J Neurosci 2004;24:5410-9. (Pubitemid 38747683)
    • (2004) Journal of Neuroscience , vol.24 , Issue.23 , pp. 5410-5419
    • Cirelli, C.1    Tononi, G.2
  • 54
    • 56949085589 scopus 로고    scopus 로고
    • Minocycline prevents the development of neuropathic pain, but not acute pain: Possible anti-inflammatory and antioxidant mechanisms
    • Padi SS, Kulkarni SK. Minocycline prevents the development of neuropathic pain, but not acute pain: possible anti-inflammatory and antioxidant mechanisms. Eur J Pharmacol 2008;601:79-87.
    • (2008) Eur J Pharmacol , vol.601 , pp. 79-87
    • Padi, S.S.1    Kulkarni, S.K.2
  • 55
    • 7644242460 scopus 로고    scopus 로고
    • Neuroprotection by tetracyclines
    • DOI 10.1016/j.tips.2004.10.001, PII S0165614704002792
    • Domercq M, Matute C. Neuroprotection by tetracyclines. Trends Pharmacol Sci 2004;25:609-12. (Pubitemid 39458165)
    • (2004) Trends in Pharmacological Sciences , vol.25 , Issue.12 , pp. 609-612
    • Domercq, M.1    Matute, C.2
  • 56
    • 67349169225 scopus 로고    scopus 로고
    • Antimicrobial susceptibility of tigecycline and comparators against bacterial isolates collected as part of the TEST study in Europe (2004-2007)
    • Norskov-Lauritsen N, Marchandin H, Dowzicky MJ. Antimicrobial susceptibility of tigecycline and comparators against bacterial isolates collected as part of the TEST study in Europe (2004-2007). Int J Antimicrob Agents 2009;34:121-30.
    • (2009) Int J Antimicrob Agents , vol.34 , pp. 121-130
    • Norskov-Lauritsen, N.1    Marchandin, H.2    Dowzicky, M.J.3
  • 58
    • 57749108208 scopus 로고    scopus 로고
    • Phagocyte migration and cellular stress induced in liver, lung, and intestine during sleep loss and sleep recovery
    • Everson CA, Thalacker CD, Hogg N. Phagocyte migration and cellular stress induced in liver, lung, and intestine during sleep loss and sleep recovery. Am J Physiol Regul Integr Comp Physiol 2008;295:R2067-R74.
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.295
    • Everson, C.A.1    Thalacker, C.D.2    Hogg, N.3
  • 59
    • 67649192019 scopus 로고    scopus 로고
    • Sleep deprivation after septic insult increases mortality independent of age
    • Friese RS, Bruns B, Sinton CM. Sleep deprivation after septic insult increases mortality independent of age. J Trauma 2009;66:50-4.
    • (2009) J Trauma , vol.66 , pp. 50-54
    • Friese, R.S.1    Bruns, B.2    Sinton, C.M.3
  • 60
    • 76649110556 scopus 로고    scopus 로고
    • Minocycline reduces astrocytic reactivation and neuroinflammation in the hippocampus of a vascular cognitive impairment rat model
    • Cai ZY, Yan Y, Chen R. Minocycline reduces astrocytic reactivation and neuroinflammation in the hippocampus of a vascular cognitive impairment rat model. Neurosci Bull 2010;26:28-36.
    • (2010) Neurosci Bull , vol.26 , pp. 28-36
    • Cai, Z.Y.1    Yan, Y.2    Chen, R.3
  • 61
    • 21244466021 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling in health and disease
    • DOI 10.1007/s00467-004-1766-8
    • Tan JC, Rabkin R. Suppressors of cytokine signaling in health and disease. Pediatr Nephrol 2005;20:567-75. (Pubitemid 41166608)
    • (2005) Pediatric Nephrology , vol.20 , Issue.5 , pp. 567-575
    • Tan, J.C.1    Rabkin, R.2
  • 62
    • 65749115383 scopus 로고    scopus 로고
    • The antibiotics doxycycline and minocycline inhibit the inflammatory responses to the Lyme disease spirochete Borrelia burgdorferi
    • Bernardino AL, Kaushal D, Philipp MT. The antibiotics doxycycline and minocycline inhibit the inflammatory responses to the Lyme disease spirochete Borrelia burgdorferi. J Infect Dis 2009;199:1379-88.
    • (2009) J Infect Dis , vol.199 , pp. 1379-1388
    • Bernardino, A.L.1    Kaushal, D.2    Philipp, M.T.3
  • 63
    • 0035871840 scopus 로고    scopus 로고
    • Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
    • Tikka T, Fiebich BL, Goldsteins G, Keinanen R, Koistinaho J. Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia. J Neurosci 2001;21:2580-8. (Pubitemid 32298200)
    • (2001) Journal of Neuroscience , vol.21 , Issue.8 , pp. 2580-2588
    • Tikka, T.1    Fiebich, B.L.2    Goldsteins, G.3    Keinanen, R.4    Koistinaho, J.5
  • 64
    • 0028843619 scopus 로고
    • Microdialysis measurement of cortical and hippocampal acetylcholine release during sleep-wake cycle in freely moving cats
    • Marrosu F, Portas C, Mascia MS, et al. Microdialysis measurement of cortical and hippocampal acetylcholine release during sleep-wake cycle in freely moving cats. Brain Res 1995;671:329-32.
    • (1995) Brain Res , vol.671 , pp. 329-332
    • Marrosu, F.1    Portas, C.2    Mascia, M.S.3
  • 65
  • 66
    • 84862254776 scopus 로고    scopus 로고
    • Neurotransmitters and their receptors
    • Sunderland, MA: Sinauer Associates
    • Purves D, Augustine GJ, Fitzpatrick D, et al. Neurotransmitters and their receptors. Neuroscience. Sunderland, MA: Sinauer Associates, 2008.
    • (2008) Neuroscience
    • Purves, D.1    Augustine, G.J.2    Fitzpatrick, D.3
  • 67
    • 0037305561 scopus 로고    scopus 로고
    • 2-integrin CD11b gene
    • DOI 10.1182/blood-2002-03-0680
    • Park H, Shelley CS, Arnaout MA. The zinc finger transcription factor ZBP-89 is a repressor of the human beta 2-integrin CD11b gene. Blood 2003;101:894-902. (Pubitemid 36139356)
    • (2003) Blood , vol.101 , Issue.3 , pp. 894-902
    • Park, H.1    Shelley, C.S.2    Arnaout, M.A.3
  • 68
    • 0038268057 scopus 로고    scopus 로고
    • ZBP-89 represses vimentin gene transcription by interacting with the transcriptional activator, Sp1
    • DOI 10.1093/nar/gkg380
    • Zhang X, Diab IH, Zehner ZE. ZBP-89 represses vimentin gene transcription by interacting with the transcriptional activator, Sp1. Nucleic Acids Res 2003;31:2900-14. (Pubitemid 37442134)
    • (2003) Nucleic Acids Research , vol.31 , Issue.11 , pp. 2900-2914
    • Zhang, X.1    Diab, I.H.2    Zehner, Z.E.3
  • 69
    • 0036849157 scopus 로고    scopus 로고
    • Effects of norepinephrine on rat cultured microglial cells that express alpha1, alpha2, beta1 and beta2 adrenergic receptors
    • DOI 10.1016/S0028-3908(02)00211-3, PII S0028390802002113
    • Mori K, Ozaki E, Zhang B, et al. Effects of norepinephrine on rat cultured microglial cells that express alpha1, alpha2, beta1 and beta2 adrenergic receptors. Neuropharmacology 2002;43:1026-34. (Pubitemid 35341238)
    • (2002) Neuropharmacology , vol.43 , Issue.6 , pp. 1026-1034
    • Mori, K.1    Ozaki, E.2    Zhang, B.3    Yang, L.4    Yokoyama, A.5    Takeda, I.6    Maeda, N.7    Sakanaka, M.8    Tanaka, J.9
  • 70
    • 0034001914 scopus 로고    scopus 로고
    • AMPA-kainate subtypes of glutamate receptor in rat cerebral microglia
    • Noda M, Nakanishi H, Nabekura J, Akaike N. AMPA-kainate subtypes of glutamate receptor in rat cerebral microglia. J Neurosci 2000;20:251-8. (Pubitemid 30220512)
    • (2000) Journal of Neuroscience , vol.20 , Issue.1 , pp. 251-258
    • Noda, M.1    Nakanishi, H.2    Nabekura, J.3    Akaike, N.4
  • 71
    • 0036599031 scopus 로고    scopus 로고
    • In vivo microdialysis measures of extracellular norepinephrine in the rat amygdala during sleep-wakefulness
    • Park SP. In vivo microdialysis measures of extracellular norepinephrine in the rat amygdala during sleep-wakefulness. J Korean Med Sci 2002;17:395-9.
    • (2002) J Korean Med Sci , vol.17 , pp. 395-399
    • Park, S.P.1
  • 72
    • 58849150000 scopus 로고    scopus 로고
    • Long-term homeostasis of extracellular glutamate in the rat cerebral cortex across sleep and waking states
    • Dash MB, Douglas CL, Vyazovskiy VV, Cirelli C, Tononi G. Long-term homeostasis of extracellular glutamate in the rat cerebral cortex across sleep and waking states. J Neurosci 2009;29:620-9.
    • (2009) J Neurosci , vol.29 , pp. 620-629
    • Dash, M.B.1    Douglas, C.L.2    Vyazovskiy, V.V.3    Cirelli, C.4    Tononi, G.5
  • 73
    • 1442299155 scopus 로고    scopus 로고
    • Differential Utilization of the Promoter of Peripheral-Type Benzodiazepine Receptor by Steroidogenic Versus Nonsteroidogenic Cell Lines and the Role of Sp1 and Sp3 in the Regulation of Basal Activity
    • DOI 10.1210/en.2003-1330
    • Giatzakis C, Papadopoulos V. Differential utilization of the promoter of peripheral-type benzodiazepine receptor by steroidogenic versus nonsteroidogenic cell lines and the role of Sp1 and Sp3 in the regulation of basal activity. Endocrinology 2004;145:1113-23. (Pubitemid 38280990)
    • (2004) Endocrinology , vol.145 , Issue.3 , pp. 1113-1123
    • Giatzakis, C.1    Papadopoulos, V.2
  • 74
    • 2942622394 scopus 로고    scopus 로고
    • Peripheral benzodiazepine receptor imaging in CNS demyelination: Functional implications of anatomical and cellular localization
    • DOI 10.1093/brain/awh161
    • Chen MK, Baidoo K, Verina T, Guilarte TR. Peripheral benzodiazepine receptor imaging in CNS demyelination: functional implications of anatomical and cellular localization. Brain 2004;127:1379-92. (Pubitemid 38745516)
    • (2004) Brain , vol.127 , Issue.6 , pp. 1379-1392
    • Chen, M.-K.1    Baidoo, K.2    Verina, T.3    Guilarte, T.R.4
  • 75
    • 45949092844 scopus 로고    scopus 로고
    • Methamphetamine causes microglial activation in the brains of human abusers
    • Sekine Y, Ouchi Y, Sugihara G, et al. Methamphetamine causes microglial activation in the brains of human abusers. J Neurosci 2008;28:5756-61.
    • (2008) J Neurosci , vol.28 , pp. 5756-5761
    • Sekine, Y.1    Ouchi, Y.2    Sugihara, G.3
  • 77
    • 71849101064 scopus 로고    scopus 로고
    • Differential regulation of microglial motility by ATP/ADP and adenosine
    • Gyoneva S, Orr AG, Traynelis SF. Differential regulation of microglial motility by ATP/ADP and adenosine. Parkinsonism Relat Disord 2009;15 Suppl 3:S195-9.
    • (2009) Parkinsonism Relat Disord , vol.15 , Issue.SUPPL. 3
    • Gyoneva, S.1    Orr, A.G.2    Traynelis, S.F.3
  • 78
    • 77954946392 scopus 로고    scopus 로고
    • Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b
    • Han C, Jin J, Xu S, Liu H, Li N, Cao X. Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b. Nat Immunol 2010;11:734-42.
    • (2010) Nat Immunol , vol.11 , pp. 734-742
    • Han, C.1    Jin, J.2    Xu, S.3    Liu, H.4    Li, N.5    Cao, X.6
  • 79
    • 74149092361 scopus 로고    scopus 로고
    • The role of galectin-3/MAC-2 in the activation of the innate- Immune function of phagocytosis in microglia in injury and disease
    • Rotshenker S. The role of galectin-3/MAC-2 in the activation of the innate- immune function of phagocytosis in microglia in injury and disease. J Mol Neurosci 2009;39:99-103.
    • (2009) J Mol Neurosci , vol.39 , pp. 99-103
    • Rotshenker, S.1
  • 81
    • 65349083298 scopus 로고    scopus 로고
    • Slow wave homeostasis and synaptic plasticity
    • Tononi G. Slow wave homeostasis and synaptic plasticity. J Clin Sleep Med 2009;5:S16-S9.
    • (2009) J Clin Sleep Med , vol.5
    • Tononi, G.1
  • 82
    • 0043158690 scopus 로고    scopus 로고
    • Sleep deprivation prior to transient global cerebral ischemia attenuates glial reaction in the rat hippocampal formation
    • Hsu JC, Lee YS, Chang CN, Ling EA, Lan CT. Sleep deprivation prior to transient global cerebral ischemia attenuates glial reaction in the rat hippocampal formation. Brain Res 2003;984:170-81.
    • (2003) Brain Res , vol.984 , pp. 170-181
    • Hsu, J.C.1    Lee, Y.S.2    Chang, C.N.3    Ling, E.A.4    Lan, C.T.5
  • 83
    • 59649117102 scopus 로고    scopus 로고
    • Microglia protect neurons against ischemia by synthesis of tumor necrosis factor
    • Lambertsen KL, Clausen BH, Babcock AA, et al. Microglia protect neurons against ischemia by synthesis of tumor necrosis factor. J Neurosci 2009;29:1319-30.
    • (2009) J Neurosci , vol.29 , pp. 1319-1330
    • Lambertsen, K.L.1    Clausen, B.H.2    Babcock, A.A.3
  • 85
    • 18144382337 scopus 로고    scopus 로고
    • On the potential role of glutamate transport in mental fatigue
    • Ronnback L, Hansson E. On the potential role of glutamate transport in mental fatigue. J Neuroinflammation 2004;1:22.
    • (2004) J Neuroinflammation , vol.1 , pp. 22
    • Ronnback, L.1    Hansson, E.2
  • 86
    • 72449161215 scopus 로고    scopus 로고
    • Amyloid-β dynamics are regulated by orexin and the sleep-wake cycle
    • Kang JE, Lim MM, Bateman RJ, et al. Amyloid-β dynamics are regulated by orexin and the sleep-wake cycle. Science 2009;326:1005-7.
    • (2009) Science , vol.326 , pp. 1005-1007
    • Kang, J.E.1    Lim, M.M.2    Bateman, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.