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Volumn 160, Issue 7, 2010, Pages 1754-1764

Spinal glial TLR4-mediated nociception and production of prostaglandin E 2 and TNF

Author keywords

astrocytes; intrathecal; lipopolysacaride; microglia; pain; prostaglandin; spinal cord; Toll like receptor 4; tumour necrosis factor

Indexed keywords

ETANERCEPT; KETOROLAC; LIPID A; LIPOPOLYSACCHARIDE; MINOCYCLINE; PENTOXIFYLLINE; PROSTAGLANDIN E2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR;

EID: 77954347484     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00811.x     Document Type: Article
Times cited : (92)

References (49)
  • 1
    • 40949095655 scopus 로고    scopus 로고
    • Guide to Receptors and Channels (GRAC)
    • 3rd edn. Suppl.
    • Alexander SP, Mathie A, Peters JA (2008). Guide to Receptors and Channels (GRAC). 3rd edn. Br J Pharmacol 153 (Suppl. 2 S1 S209.
    • (2008) Br J Pharmacol , vol.153 , Issue.2
    • Alexander, S.P.1    Mathie, A.2    Peters, J.A.3
  • 3
    • 51349166320 scopus 로고    scopus 로고
    • Glial TLR4 receptor as new target to treat neuropathic pain: Efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice
    • Bettoni I, Comelli F, Rossini C, Granucci F, Giagnoni G, Peri F et al. (2008). Glial TLR4 receptor as new target to treat neuropathic pain: efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice. Glia 56:1312 1319.
    • (2008) Glia , vol.56 , pp. 1312-1319
    • Bettoni, I.1    Comelli, F.2    Rossini, C.3    Granucci, F.4    Giagnoni, G.5    Peri, F.6
  • 4
    • 34047266964 scopus 로고    scopus 로고
    • Increased tumor necrosis factor-alpha and prostaglandin E2 concentrations in the cerebrospinal fluid of rats with inflammatory hyperalgesia: The effects of analgesic drugs
    • Bianchi M, Martucci C, Ferrario P, Franchi S, Sacerdote P (2007). Increased tumor necrosis factor-alpha and prostaglandin E2 concentrations in the cerebrospinal fluid of rats with inflammatory hyperalgesia: the effects of analgesic drugs. Anesth Analg 104:949 954.
    • (2007) Anesth Analg , vol.104 , pp. 949-954
    • Bianchi, M.1    Martucci, C.2    Ferrario, P.3    Franchi, S.4    Sacerdote, P.5
  • 5
    • 0042377367 scopus 로고    scopus 로고
    • Cultured astrocytes express toll-like receptors for bacterial products
    • Bowman CC, Rasley A, Tranguch SL, Marriott I (2003). Cultured astrocytes express toll-like receptors for bacterial products. Glia 43:281 291.
    • (2003) Glia , vol.43 , pp. 281-291
    • Bowman, C.C.1    Rasley, A.2    Tranguch, S.L.3    Marriott, I.4
  • 6
    • 34547928769 scopus 로고    scopus 로고
    • TLR-4 and sustained calcium agonists synergistically produce eicosanoids independent of protein synthesis in RAW264.7 cells
    • Buczynski MW, Stephens DL, Bowers-Gentry RC, Grkovich A, Deems RA, Dennis EA (2007). TLR-4 and sustained calcium agonists synergistically produce eicosanoids independent of protein synthesis in RAW264.7 cells. J Biol Chem 282:22834 22847.
    • (2007) J Biol Chem , vol.282 , pp. 22834-22847
    • Buczynski, M.W.1    Stephens, D.L.2    Bowers-Gentry, R.C.3    Grkovich, A.4    Deems, R.A.5    Dennis, E.A.6
  • 7
    • 67650531422 scopus 로고    scopus 로고
    • Thematic review series: Proteomics. An integrated omics analysis of eicosanoid biology
    • Buczynski MW, Dumlao DS, Dennis EA (2009). Thematic review series: proteomics. An integrated omics analysis of eicosanoid biology. J Lipid Res 50:1015 1038.
    • (2009) J Lipid Res , vol.50 , pp. 1015-1038
    • Buczynski, M.W.1    Dumlao, D.S.2    Dennis, E.A.3
  • 8
    • 0026662652 scopus 로고
    • Cytokine release from microglia: Differential inhibition by pentoxifylline and dexamethasone
    • Chao CC, Hu S, Close K, Choi CS, Molitor TW, Novick WJ et al. (1992). Cytokine release from microglia: differential inhibition by pentoxifylline and dexamethasone. J Infect Dis 166:847 853.
    • (1992) J Infect Dis , vol.166 , pp. 847-853
    • Chao, C.C.1    Hu, S.2    Close, K.3    Choi, C.S.4    Molitor, T.W.5    Novick, W.J.6
  • 12
    • 41249086003 scopus 로고    scopus 로고
    • Detection and quantitation of eicosanoids via high performance liquid chromatography-electrospray ionization-mass spectrometry
    • Deems R, Buczynski MW, Bowers-Gentry R, Harkewicz R, Dennis EA (2007). Detection and quantitation of eicosanoids via high performance liquid chromatography-electrospray ionization-mass spectrometry. Methods Enzymol 432:59 82.
    • (2007) Methods Enzymol , vol.432 , pp. 59-82
    • Deems, R.1    Buczynski, M.W.2    Bowers-Gentry, R.3    Harkewicz, R.4    Dennis, E.A.5
  • 13
    • 0020461752 scopus 로고
    • Production of prostaglandin e and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells
    • Fontana A, Kristensen F, Dubs R, Gemsa D, Weber E (1982). Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells. J Immunol 129:2413 2419.
    • (1982) J Immunol , vol.129 , pp. 2413-2419
    • Fontana, A.1    Kristensen, F.2    Dubs, R.3    Gemsa, D.4    Weber, E.5
  • 14
    • 0038257594 scopus 로고
    • A glia-neural theory of brain function
    • Galambos R (1961). A glia-neural theory of brain function. Proc Natl Acad Sci USA 47:129 136.
    • (1961) Proc Natl Acad Sci USA , vol.47 , pp. 129-136
    • Galambos, R.1
  • 15
    • 34548459868 scopus 로고    scopus 로고
    • Structure and function of Toll receptors and their ligands
    • Gay NJ, Gangloff M (2007). Structure and function of Toll receptors and their ligands. Annu Rev Biochem 76:141 165.
    • (2007) Annu Rev Biochem , vol.76 , pp. 141-165
    • Gay, N.J.1    Gangloff, M.2
  • 16
    • 0032078383 scopus 로고    scopus 로고
    • Pain modulatory actions of cytokines and prostaglandin E2 in the brain
    • Hori T, Oka T, Hosoi M, Aou S (1998). Pain modulatory actions of cytokines and prostaglandin E2 in the brain. Ann N Y Acad Sci 840:269 281.
    • (1998) Ann N y Acad Sci , vol.840 , pp. 269-281
    • Hori, T.1    Oka, T.2    Hosoi, M.3    Aou, S.4
  • 18
    • 70449526311 scopus 로고    scopus 로고
    • Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats
    • Hutchinson MR, Ramos KM, Loram LC, Wieseler J, Sholar PW, Kearney JJ et al. (2009b). Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats. Neuroscience 164:1821 1832.
    • (2009) Neuroscience , vol.164 , pp. 1821-1832
    • Hutchinson, M.R.1    Ramos, K.M.2    Loram, L.C.3    Wieseler, J.4    Sholar, P.W.5    Kearney, J.J.6
  • 19
    • 25444498280 scopus 로고    scopus 로고
    • TLR signaling tailors innate immune responses in human microglia and astrocytes
    • Jack CS, Arbour N, Manusow J, Montgrain V, Blain M, McCrea E et al. (2005). TLR signaling tailors innate immune responses in human microglia and astrocytes. J Immunol 175:4320 4330.
    • (2005) J Immunol , vol.175 , pp. 4320-4330
    • Jack, C.S.1    Arbour, N.2    Manusow, J.3    Montgrain, V.4    Blain, M.5    McCrea, E.6
  • 20
    • 4344680129 scopus 로고    scopus 로고
    • Tolerance develops to the effect of lipopolysaccharides on movement-evoked hyperalgesia when administered chronically by a systemic but not an intrathecal route
    • Kehl LJ, Kovacs KJ, Larson AA (2004). Tolerance develops to the effect of lipopolysaccharides on movement-evoked hyperalgesia when administered chronically by a systemic but not an intrathecal route. Pain 111:104 115.
    • (2004) Pain , vol.111 , pp. 104-115
    • Kehl, L.J.1    Kovacs, K.J.2    Larson, A.A.3
  • 22
    • 1242291761 scopus 로고    scopus 로고
    • Nonopioid actions of intrathecal dynorphin evoke spinal excitatory amino acid and prostaglandin E2 release mediated by cyclooxygenase-1 and -2
    • Koetzner L, Hua XY, Lai J, Porreca F, Yaksh T (2004). Nonopioid actions of intrathecal dynorphin evoke spinal excitatory amino acid and prostaglandin E2 release mediated by cyclooxygenase-1 and -2. J Neurosci 24:1451 1458.
    • (2004) J Neurosci , vol.24 , pp. 1451-1458
    • Koetzner, L.1    Hua, X.Y.2    Lai, J.3    Porreca, F.4    Yaksh, T.5
  • 23
    • 0035907302 scopus 로고    scopus 로고
    • Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
    • Lee JY, Sohn KH, Rhee SH, Hwang D (2001). Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J Biol Chem 276:16683 16689.
    • (2001) J Biol Chem , vol.276 , pp. 16683-16689
    • Lee, J.Y.1    Sohn, K.H.2    Rhee, S.H.3    Hwang, D.4
  • 24
    • 0036548360 scopus 로고    scopus 로고
    • The toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS
    • Lehnardt S, Lachance C, Patrizi S, Lefebvre S, Follett PL, Jensen FE et al. (2002). The toll-like receptor TLR4 is necessary for lipopolysaccharide- induced oligodendrocyte injury in the CNS. J Neurosci 22:2478 2486.
    • (2002) J Neurosci , vol.22 , pp. 2478-2486
    • Lehnardt, S.1    Lachance, C.2    Patrizi, S.3    Lefebvre, S.4    Follett, P.L.5    Jensen, F.E.6
  • 25
    • 33846263709 scopus 로고    scopus 로고
    • Pentoxifylline attenuates the development of hyperalgesia in a rat model of neuropathic pain
    • Liu J, Feng X, Yu M, Xie W, Zhao X, Li W et al. (2007). Pentoxifylline attenuates the development of hyperalgesia in a rat model of neuropathic pain. Neurosci Lett 412:268 272.
    • (2007) Neurosci Lett , vol.412 , pp. 268-272
    • Liu, J.1    Feng, X.2    Yu, M.3    Xie, W.4    Zhao, X.5    Li, W.6
  • 26
    • 0027301614 scopus 로고
    • Interleukin-1 mediates the behavioral hyperalgesia produced by lithium chloride and endotoxin
    • Maier SF, Wiertelak EP, Martin D, Watkins LR (1993). Interleukin-1 mediates the behavioral hyperalgesia produced by lithium chloride and endotoxin. Brain Res 623:321 324.
    • (1993) Brain Res , vol.623 , pp. 321-324
    • Maier, S.F.1    Wiertelak, E.P.2    Martin, D.3    Watkins, L.R.4
  • 27
    • 0028892707 scopus 로고
    • The spinal loop dialysis catheter: Characterization of use in the unanesthetized rat
    • Marsala M, Malmberg AB, Yaksh TL (1995). The spinal loop dialysis catheter: characterization of use in the unanesthetized rat. J Neurosci Methods 62:43 53.
    • (1995) J Neurosci Methods , vol.62 , pp. 43-53
    • Marsala, M.1    Malmberg, A.B.2    Yaksh, T.L.3
  • 28
    • 0028027868 scopus 로고
    • The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat
    • Meller ST, Dykstra C, Grzybycki D, Murphy S, Gebhart GF (1994). The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat. Neuropharmacology 33:1471 1478.
    • (1994) Neuropharmacology , vol.33 , pp. 1471-1478
    • Meller, S.T.1    Dykstra, C.2    Grzybycki, D.3    Murphy, S.4    Gebhart, G.F.5
  • 29
    • 57749200564 scopus 로고    scopus 로고
    • Pathological and protective roles of glia in chronic pain
    • Milligan ED, Watkins LR (2009). Pathological and protective roles of glia in chronic pain. Nat Rev Neurosci 10:23 36.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 23-36
    • Milligan, E.D.1    Watkins, L.R.2
  • 30
    • 1642384019 scopus 로고    scopus 로고
    • Innate recognition of lipopolysaccharide by Toll-like receptor 4-MD-2
    • DOI 10.1016/j.tim.2004.02.009, PII S0966842X04000502
    • Miyake K (2004). Innate recognition of lipopolysaccharide by Toll-like receptor 4-MD-2. Trends Microbiol 12:186 192. (Pubitemid 38393739)
    • (2004) Trends in Microbiology , vol.12 , Issue.4 , pp. 186-192
    • Miyake, K.1
  • 31
    • 33947629255 scopus 로고    scopus 로고
    • Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors
    • Miyake K (2007). Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors. Semin Immunol 19:3 10.
    • (2007) Semin Immunol , vol.19 , pp. 3-10
    • Miyake, K.1
  • 32
    • 0036618421 scopus 로고    scopus 로고
    • Role of nuclear factor kappaB in synovial inflammation
    • Muller-Ladner U, Gay RE, Gay S (2002). Role of nuclear factor kappaB in synovial inflammation. Curr Rheumatol Rep 4:201 207.
    • (2002) Curr Rheumatol Rep , vol.4 , pp. 201-207
    • Muller-Ladner, U.1    Gay, R.E.2    Gay, S.3
  • 33
    • 33646804835 scopus 로고    scopus 로고
    • Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4
    • Raetz CR, Garrett TA, Reynolds CM, Shaw WA, Moore JD, Smith DC et al. (2006). Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. J Lipid Res 47:1097 1111.
    • (2006) J Lipid Res , vol.47 , pp. 1097-1111
    • Raetz, C.R.1    Garrett, T.A.2    Reynolds, C.M.3    Shaw, W.A.4    Moore, J.D.5    Smith, D.C.6
  • 34
    • 3242758909 scopus 로고    scopus 로고
    • Complete Freunds adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS
    • Raghavendra V, Tanga FY, DeLeo JA (2004). Complete Freunds adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS. Eur J Neurosci 20:467 473.
    • (2004) Eur J Neurosci , vol.20 , pp. 467-473
    • Raghavendra, V.1    Tanga, F.Y.2    Deleo, J.A.3
  • 35
    • 0033835476 scopus 로고    scopus 로고
    • Intrathecally administered endotoxin or cytokines produce allodynia, hyperalgesia and changes in spinal cord neuronal responses to nociceptive stimuli in the rat
    • Reeve AJ, Patel S, Fox A, Walker K, Urban L (2000). Intrathecally administered endotoxin or cytokines produce allodynia, hyperalgesia and changes in spinal cord neuronal responses to nociceptive stimuli in the rat. Eur J Pain 4:247 257.
    • (2000) Eur J Pain , vol.4 , pp. 247-257
    • Reeve, A.J.1    Patel, S.2    Fox, A.3    Walker, K.4    Urban, L.5
  • 36
    • 0024401054 scopus 로고
    • Production of tumor necrosis factor-alpha by microglia and astrocytes in culture
    • Sawada M, Kondo N, Suzumura A, Marunouchi T (1989). Production of tumor necrosis factor-alpha by microglia and astrocytes in culture. Brain Res 491:394 397.
    • (1989) Brain Res , vol.491 , pp. 394-397
    • Sawada, M.1    Kondo, N.2    Suzumura, A.3    Marunouchi, T.4
  • 37
    • 0031593611 scopus 로고    scopus 로고
    • Pathological immuno-reactions of glial cells in Alzheimer's disease and possible sites of interference
    • Schubert P, Ogata T, Miyazaki H, Marchini C, Ferroni S, Rudolphi K (1998). Pathological immuno-reactions of glial cells in Alzheimer's disease and possible sites of interference. J Neural Transm Suppl 54:167 174.
    • (1998) J Neural Transm Suppl , vol.54 , pp. 167-174
    • Schubert, P.1    Ogata, T.2    Miyazaki, H.3    Marchini, C.4    Ferroni, S.5    Rudolphi, K.6
  • 38
    • 0026466633 scopus 로고
    • Preparation and characterization of type 1 astrocytes cultured from adult rat cortex, cerebellum, and striatum
    • Schwartz JP, Wilson DJ (1992). Preparation and characterization of type 1 astrocytes cultured from adult rat cortex, cerebellum, and striatum. Glia 5:75 80.
    • (1992) Glia , vol.5 , pp. 75-80
    • Schwartz, J.P.1    Wilson, D.J.2
  • 39
    • 58849137575 scopus 로고    scopus 로고
    • The expression of tumor necrosis factor-alpha (TNF-alpha) by the intrathecal injection of lipopolysaccharide in the rat spinal cord
    • Shen A, Zhou D, Shen Q, Liu HO, Sun L, Liu Y et al. (2009). The expression of tumor necrosis factor-alpha (TNF-alpha) by the intrathecal injection of lipopolysaccharide in the rat spinal cord. Neurochem Res 34:333 341.
    • (2009) Neurochem Res , vol.34 , pp. 333-341
    • Shen, A.1    Zhou, D.2    Shen, Q.3    Liu, H.O.4    Sun, L.5    Liu, Y.6
  • 40
    • 0030791764 scopus 로고    scopus 로고
    • Reorientation of prostanoid production accompanies "activation" of adult microglial cells in culture
    • Slepko N, Minghetti L, Polazzi E, Nicolini A, Levi G (1997). Reorientation of prostanoid production accompanies "activation" of adult microglial cells in culture. J Neurosci Res 49:292 300.
    • (1997) J Neurosci Res , vol.49 , pp. 292-300
    • Slepko, N.1    Minghetti, L.2    Polazzi, E.3    Nicolini, A.4    Levi, G.5
  • 41
    • 0035018058 scopus 로고    scopus 로고
    • Propentofylline, a glial modulating agent, exhibits antiallodynic properties in a rat model of neuropathic pain
    • Sweitzer SM, Schubert P, DeLeo JA (2001). Propentofylline, a glial modulating agent, exhibits antiallodynic properties in a rat model of neuropathic pain. J Pharmacol Exp Ther 297:1210 1217.
    • (2001) J Pharmacol Exp Ther , vol.297 , pp. 1210-1217
    • Sweitzer, S.M.1    Schubert, P.2    Deleo, J.A.3
  • 42
    • 0742324860 scopus 로고    scopus 로고
    • TLR signaling pathways
    • Takeda K, Akira S (2004). TLR signaling pathways. Semin Immunol 16:3 9.
    • (2004) Semin Immunol , vol.16 , pp. 3-9
    • Takeda, K.1    Akira, S.2
  • 43
    • 0347814979 scopus 로고    scopus 로고
    • Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain
    • Tanga FY, Raghavendra V, DeLeo JA (2004). Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain. Neurochem Int 45:397 407.
    • (2004) Neurochem Int , vol.45 , pp. 397-407
    • Tanga, F.Y.1    Raghavendra, V.2    Deleo, J.A.3
  • 44
    • 17644414137 scopus 로고    scopus 로고
    • The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy
    • Tanga FY, Nutile-McMenemy N, DeLeo JA (2005). The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy. Proc Natl Acad Sci USA 102:5856 5861.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5856-5861
    • Tanga, F.Y.1    Nutile-Mcmenemy, N.2    Deleo, J.A.3
  • 45
    • 41549147179 scopus 로고    scopus 로고
    • Propentofylline-induced astrocyte modulation leads to alterations in glial glutamate promoter activation following spinal nerve transection
    • Tawfik VL, Regan MR, Haenggeli C, Lacroix-Fralish ML, Nutile-McMenemy N, Perez N et al. (2008). Propentofylline-induced astrocyte modulation leads to alterations in glial glutamate promoter activation following spinal nerve transection. Neuroscience 152:1086 1092.
    • (2008) Neuroscience , vol.152 , pp. 1086-1092
    • Tawfik, V.L.1    Regan, M.R.2    Haenggeli, C.3    Lacroix-Fralish, M.L.4    Nutile-Mcmenemy, N.5    Perez, N.6
  • 46
    • 0035876916 scopus 로고    scopus 로고
    • Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia
    • Tikka TM, Koistinaho JE (2001b). Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia. J Immunol 166:7527 7533.
    • (2001) J Immunol , vol.166 , pp. 7527-7533
    • Tikka, T.M.1    Koistinaho, J.E.2
  • 47
    • 0035871840 scopus 로고    scopus 로고
    • Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
    • Tikka T, Fiebich BL, Goldsteins G, Keinanen R, Koistinaho J (2001a). Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia. J Neurosci 21:2580 2588.
    • (2001) J Neurosci , vol.21 , pp. 2580-2588
    • Tikka, T.1    Fiebich, B.L.2    Goldsteins, G.3    Keinanen, R.4    Koistinaho, J.5
  • 48
    • 0017036162 scopus 로고
    • Chronic catheterization of the spinal subarachnoid space
    • Yaksh TL, Rudy TS (1976). Chronic catheterization of the spinal subarachnoid space. Physiol Behav 17:1031 1036.
    • (1976) Physiol Behav , vol.17 , pp. 1031-1036
    • Yaksh, T.L.1    Rudy, T.S.2
  • 49
    • 21844437380 scopus 로고    scopus 로고
    • Intraneural injection of interleukin-1beta and tumor necrosis factor-alpha into rat sciatic nerve at physiological doses induces signs of neuropathic pain
    • Zelenka M, Schafers M, Sommer C (2005). Intraneural injection of interleukin-1beta and tumor necrosis factor-alpha into rat sciatic nerve at physiological doses induces signs of neuropathic pain. Pain 116:257 263.
    • (2005) Pain , vol.116 , pp. 257-263
    • Zelenka, M.1    Schafers, M.2    Sommer, C.3


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