메뉴 건너뛰기




Volumn 103, Issue 5, 2007, Pages 2035-2046

Minocycline decreases in vitro microglial motility, β1- integrin, and Kv1.3 channel expression

Author keywords

Chemokinesis; Chronic pain; Migration; Persistent pain states; Primary microglial cultures

Indexed keywords

ADENOSINE DIPHOSPHATE; BETA1 INTEGRIN; BETA2 INTEGRIN; MINOCYCLINE; POTASSIUM; POTASSIUM CHANNEL KV1.3;

EID: 36249012543     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.04889.x     Document Type: Article
Times cited : (76)

References (50)
  • 3
    • 0036020148 scopus 로고    scopus 로고
    • Molecular proximity of Kv1.3 voltage-gated potassium channels and beta(1)-integrins on the plasma membrane of melanoma cells: Effects of cell adherence and channel blockers
    • Artym V. V. Petty H. R. (2002) Molecular proximity of Kv1.3 voltage-gated potassium channels and beta(1)-integrins on the plasma membrane of melanoma cells: effects of cell adherence and channel blockers. J. Gen. Physiol. 120, 29 37.
    • (2002) J. Gen. Physiol. , vol.120 , pp. 29-37
    • Artym, V.V.1    Petty, H.R.2
  • 4
    • 0036260089 scopus 로고    scopus 로고
    • Targeting leukocyte MMPs and transmigration: Minocycline as a potential therapy for multiple sclerosis
    • Brundula V., Rewcastle N. B., Metz L. M., Bernard C. C. Yong V. W. (2002) Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis. Brain 125, 1297 1308.
    • (2002) Brain , vol.125 , pp. 1297-1308
    • Brundula, V.1    Rewcastle, N.B.2    Metz, L.M.3    Bernard, C.C.4    Yong, V.W.5
  • 5
    • 34347251609 scopus 로고    scopus 로고
    • Induction of interleukin-1beta by interleukin-4 in lipopolysaccharide- treated mixed glial cultures: Microglial-dependent effects
    • Cao L., Fei L., Chang T. T. Deleo J. A. (2007) Induction of interleukin-1beta by interleukin-4 in lipopolysaccharide-treated mixed glial cultures: microglial-dependent effects. J. Neurochem. 102, 408 419.
    • (2007) J. Neurochem. , vol.102 , pp. 408-419
    • Cao, L.1    Fei, L.2    Chang, T.T.3    Deleo, J.A.4
  • 6
    • 0035831307 scopus 로고    scopus 로고
    • Beta-amyloid peptide induces the expression of voltage dependent outward rectifying K+ channels in rat microglia
    • Chung S., Lee J., Joe E. H. Uhm D. Y. (2001) Beta-amyloid peptide induces the expression of voltage dependent outward rectifying K+ channels in rat microglia. Neurosci. Lett. 300, 67 70.
    • (2001) Neurosci. Lett. , vol.300 , pp. 67-70
    • Chung, S.1    Lee, J.2    Joe, E.H.3    Uhm, D.Y.4
  • 7
    • 0035252354 scopus 로고    scopus 로고
    • The role of neuroinflammation and neuroimmune activation in persistent pain
    • DeLeo J. A. Yezierski R. P. (2001) The role of neuroinflammation and neuroimmune activation in persistent pain. Pain 90, 1 6.
    • (2001) Pain , vol.90 , pp. 1-6
    • Deleo, J.A.1    Yezierski, R.P.2
  • 8
    • 1642579573 scopus 로고    scopus 로고
    • Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesia
    • DeLeo J. A., Tanga F. Y. Tawfik V. L. (2004) Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesia. Neuroscientist 10, 40 52.
    • (2004) Neuroscientist , vol.10 , pp. 40-52
    • Deleo, J.A.1    Tanga, F.Y.2    Tawfik, V.L.3
  • 10
    • 0033460317 scopus 로고    scopus 로고
    • Morphological, immunophenotypical and electrophysiological properties of resting microglia in vitro
    • Eder C., Schilling T., Heinemann U., Haas D., Hailer N. Nitsch R. (1999) Morphological, immunophenotypical and electrophysiological properties of resting microglia in vitro. Eur. J. Neurosci. 11, 4251 4261.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 4251-4261
    • Eder, C.1    Schilling, T.2    Heinemann, U.3    Haas, D.4    Hailer, N.5    Nitsch, R.6
  • 11
    • 22144464454 scopus 로고    scopus 로고
    • Minocycline does not inhibit microglia proliferation or neuronal regeneration in the facial nucleus following crush injury
    • Fendrick S. E., Miller K. R. Streit W. J. (2005) Minocycline does not inhibit microglia proliferation or neuronal regeneration in the facial nucleus following crush injury. Neurosci. Lett. 385, 220 223.
    • (2005) Neurosci. Lett. , vol.385 , pp. 220-223
    • Fendrick, S.E.1    Miller, K.R.2    Streit, W.J.3
  • 12
    • 23444436221 scopus 로고    scopus 로고
    • Microglia Kv1.3 channels contribute to their ability to kill neurons
    • Fordyce C. B., Jagasia R., Zhu X. Schlichter L. C. (2005) Microglia Kv1.3 channels contribute to their ability to kill neurons. J. Neurosci. 25, 7139 7149.
    • (2005) J. Neurosci. , vol.25 , pp. 7139-7149
    • Fordyce, C.B.1    Jagasia, R.2    Zhu, X.3    Schlichter, L.C.4
  • 13
    • 0029166259 scopus 로고
    • Production and function of monocyte chemoattractant protein-1 and other beta-chemokines in murine glial cells
    • Hayashi M., Luo Y., Laning J., Strieter R. M. Dorf M. E. (1995) Production and function of monocyte chemoattractant protein-1 and other beta-chemokines in murine glial cells. J. Neuroimmunol. 60, 143 150.
    • (1995) J. Neuroimmunol. , vol.60 , pp. 143-150
    • Hayashi, M.1    Luo, Y.2    Laning, J.3    Strieter, R.M.4    Dorf, M.E.5
  • 15
    • 0032428177 scopus 로고    scopus 로고
    • Activated microglial cells migrate towards sites of excitotoxic neuronal injury inside organotypic hippocampal slice cultures
    • Heppner F. L., Skutella T., Hailer N. P., Haas D. Nitsch R. (1998) Activated microglial cells migrate towards sites of excitotoxic neuronal injury inside organotypic hippocampal slice cultures. Eur. J. Neurosci. 10, 3284 3290.
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 3284-3290
    • Heppner, F.L.1    Skutella, T.2    Hailer, N.P.3    Haas, D.4    Nitsch, R.5
  • 16
    • 10744228913 scopus 로고    scopus 로고
    • Minocycline is protective in a mouse model of Huntington's disease
    • Hersch S., Fink K., Vonsattel J. P. Friedlander R. M. (2003) Minocycline is protective in a mouse model of Huntington's disease. Ann. Neurol. 54, 841.
    • (2003) Ann. Neurol. , vol.54 , pp. 841
    • Hersch, S.1    Fink, K.2    Vonsattel, J.P.3    Friedlander, R.M.4
  • 17
    • 0025043211 scopus 로고
    • Cultured microglial cells have a distinct pattern of membrane channels different from peritoneal macrophages
    • Kettenmann H., Hoppe D., Gottmann K., Banati R. Kreutzberg G. (1990) Cultured microglial cells have a distinct pattern of membrane channels different from peritoneal macrophages. J. Neurosci. Res. 26, 278 287.
    • (1990) J. Neurosci. Res. , vol.26 , pp. 278-287
    • Kettenmann, H.1    Hoppe, D.2    Gottmann, K.3    Banati, R.4    Kreutzberg, G.5
  • 18
    • 0033575752 scopus 로고    scopus 로고
    • Integrin family of cell adhesion molecules in the injured brain: Regulation and cellular localization in the normal and regenerating mouse facial motor nucleus
    • Kloss C. U., Werner A., Klein M. A., Shen J., Menuz K., Probst J. C., Kreutzberg G. W. Raivich G. (1999) Integrin family of cell adhesion molecules in the injured brain: regulation and cellular localization in the normal and regenerating mouse facial motor nucleus. J. Comp. Neurol. 411, 162 178.
    • (1999) J. Comp. Neurol. , vol.411 , pp. 162-178
    • Kloss, C.U.1    Werner, A.2    Klein, M.A.3    Shen, J.4    Menuz, K.5    Probst, J.C.6    Kreutzberg, G.W.7    Raivich, G.8
  • 19
    • 0035120226 scopus 로고    scopus 로고
    • Effect of lipopolysaccharide on the morphology and integrin immunoreactivity of ramified microglia in the mouse brain and in cell culture
    • Kloss C. U., Bohatschek M., Kreutzberg G. W. Raivich G. (2001) Effect of lipopolysaccharide on the morphology and integrin immunoreactivity of ramified microglia in the mouse brain and in cell culture. Exp. Neurol. 168, 32 46.
    • (2001) Exp. Neurol. , vol.168 , pp. 32-46
    • Kloss, C.U.1    Bohatschek, M.2    Kreutzberg, G.W.3    Raivich, G.4
  • 21
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg G. W. (1996) Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19, 312 318.
    • (1996) Trends Neurosci. , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 22
    • 33744961786 scopus 로고    scopus 로고
    • Differential spinal cord gene expression in rodent models of radicular and neuropathic pain
    • La Croix-Fralish M. L., Tawfick V. L., Tanga F. Y., Spratt K. F. De Leo J. A. (2006) Differential spinal cord gene expression in rodent models of radicular and neuropathic pain. Anethesiology 104, 1283.
    • (2006) Anethesiology , vol.104 , pp. 1283
    • La Croix-Fralish, M.L.1    Tawfick, V.L.2    Tanga, F.Y.3    Spratt, K.F.4    De Leo, J.A.5
  • 23
    • 17044417657 scopus 로고    scopus 로고
    • Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation
    • Ledeboer A., Sloane E. M., Milligan E. D., Frank M. G., Mahony J. H., Maier S. F. Watkins L. R. (2005) Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation. Pain 115, 71 83.
    • (2005) Pain , vol.115 , pp. 71-83
    • Ledeboer, A.1    Sloane, E.M.2    Milligan, E.D.3    Frank, M.G.4    Mahony, J.H.5    Maier, S.F.6    Watkins, L.R.7
  • 24
    • 0034600069 scopus 로고    scopus 로고
    • Extracellular K(+) and opening of voltage-gated potassium channels activate T cell integrin function: Physical and functional association between Kv1.3 channels and beta1 integrins
    • Levite M., Cahalon L., Peretz A., Hershkoviz R., Sobko A., Ariel A., Desai R., Attali B. Lider O. (2000) Extracellular K(+) and opening of voltage-gated potassium channels activate T cell integrin function: physical and functional association between Kv1.3 channels and beta1 integrins. J. Exp. Med. 191, 1167 1176.
    • (2000) J. Exp. Med. , vol.191 , pp. 1167-1176
    • Levite, M.1    Cahalon, L.2    Peretz, A.3    Hershkoviz, R.4    Sobko, A.5    Ariel, A.6    Desai, R.7    Attali, B.8    Lider, O.9
  • 25
    • 0036522981 scopus 로고    scopus 로고
    • Cytokines regulate microglial adhesion to laminin and astrocyte extracellular matrix via protein kinase C-dependent activation of the alpha6beta1 integrin
    • Milner R. Campbell I. L. (2002) Cytokines regulate microglial adhesion to laminin and astrocyte extracellular matrix via protein kinase C-dependent activation of the alpha6beta1 integrin. J. Neurosci. 22, 1562 1572.
    • (2002) J. Neurosci. , vol.22 , pp. 1562-1572
    • Milner, R.1    Campbell, I.L.2
  • 26
    • 0037377947 scopus 로고    scopus 로고
    • The extracellular matrix and cytokines regulate microglial integrin expression and activation
    • Milner R. Campbell I. L. (2003) The extracellular matrix and cytokines regulate microglial integrin expression and activation. J. Immunol. 170, 3850 3858.
    • (2003) J. Immunol. , vol.170 , pp. 3850-3858
    • Milner, R.1    Campbell, I.L.2
  • 27
    • 0035919917 scopus 로고    scopus 로고
    • Ability of rat microglia to uptake extracellular glutamate
    • Nakajima K., Tohyama Y., Kohsaka S. Kurihara T. (2001) Ability of rat microglia to uptake extracellular glutamate. Neurosci. Lett. 307, 171 174.
    • (2001) Neurosci. Lett. , vol.307 , pp. 171-174
    • Nakajima, K.1    Tohyama, Y.2    Kohsaka, S.3    Kurihara, T.4
  • 29
    • 27844524059 scopus 로고    scopus 로고
    • Involvement of beta1 integrin in microglial chemotaxis and proliferation on fibronectin: Different regulations by ADP through PKA
    • Nasu-Tada K., Koizumi S. Inoue K. (2005) Involvement of beta1 integrin in microglial chemotaxis and proliferation on fibronectin: different regulations by ADP through PKA. Glia 52, 98 107.
    • (2005) Glia , vol.52 , pp. 98-107
    • Nasu-Tada, K.1    Koizumi, S.2    Inoue, K.3
  • 30
    • 25844455228 scopus 로고    scopus 로고
    • - currents regulate steady-state and dynamic membrane potentials in cultured rat microglia
    • - currents regulate steady-state and dynamic membrane potentials in cultured rat microglia. J. Physiol. 567, 869 890.
    • (2005) J. Physiol. , vol.567 , pp. 869-890
    • Newell, E.W.1    Schlichter, L.C.2
  • 31
    • 34447540331 scopus 로고    scopus 로고
    • Minocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC)alpha/betaII
    • Nikodemova M., Watters J. J., Jackson S. J., Yang S. K. Duncan I. D. (2007) Minocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC)alpha/betaII. J. Biol. Chem. 282, 15208 15216.
    • (2007) J. Biol. Chem. , vol.282 , pp. 15208-15216
    • Nikodemova, M.1    Watters, J.J.2    Jackson, S.J.3    Yang, S.K.4    Duncan, I.D.5
  • 32
    • 0028203597 scopus 로고
    • Voltage-dependent potassium channels in activated rat microglia
    • Norenberg W., Gebicke-Haerter P. J. Illes P. (1994) Voltage-dependent potassium channels in activated rat microglia. J. Physiol. 475, 15 32.
    • (1994) J. Physiol. , vol.475 , pp. 15-32
    • Norenberg, W.1    Gebicke-Haerter, P.J.2    Illes, P.3
  • 33
    • 0028817174 scopus 로고
    • MCP-1-stimulated monocytes preferentially utilize beta 2-integrins to migrate on laminin and fibronectin
    • Penberthy T. W., Jiang Y., Luscinskas F. W. Graves D. T. (1995) MCP-1-stimulated monocytes preferentially utilize beta 2-integrins to migrate on laminin and fibronectin. Am. J. Physiol. 269, C60 C68.
    • (1995) Am. J. Physiol. , vol.269
    • Penberthy, T.W.1    Jiang, Y.2    Luscinskas, F.W.3    Graves, D.T.4
  • 35
    • 0037622717 scopus 로고    scopus 로고
    • Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy
    • Raghavendra V., Tanga F. DeLeo J. A. (2003) Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy. J. Pharmacol. Exp. Ther. 306, 624 630.
    • (2003) J. Pharmacol. Exp. Ther. , vol.306 , pp. 624-630
    • Raghavendra, V.1    Tanga, F.2    Deleo, J.A.3
  • 36
    • 0036934895 scopus 로고    scopus 로고
    • Cytotoxic potential of proinflammatory cytokines: Combined deletion of TNF receptors TNFR1 and TNFR2 prevents motoneuron cell death after facial axotomy in adult mouse
    • Raivich G., Liu Z. Q., Kloss C. U., Labow M., Bluethmann H. Bohatschek M. (2002) Cytotoxic potential of proinflammatory cytokines: combined deletion of TNF receptors TNFR1 and TNFR2 prevents motoneuron cell death after facial axotomy in adult mouse. Exp. Neurol. 178, 186 193.
    • (2002) Exp. Neurol. , vol.178 , pp. 186-193
    • Raivich, G.1    Liu, Z.Q.2    Kloss, C.U.3    Labow, M.4    Bluethmann, H.5    Bohatschek, M.6
  • 37
    • 0036972549 scopus 로고    scopus 로고
    • The role of cytokines in the initiation and maintenance of chronic pain
    • Rutkowski M. D. DeLeo J. A. (2002) The role of cytokines in the initiation and maintenance of chronic pain. Drug News Perspect. 15, 626 632.
    • (2002) Drug News Perspect. , vol.15 , pp. 626-632
    • Rutkowski, M.D.1    Deleo, J.A.2
  • 39
    • 0035101188 scopus 로고    scopus 로고
    • Dynamics of microglial activation: A confocal time-lapse analysis in hippocampal slices
    • Stence N., Waite M. Dailey M. E. (2001) Dynamics of microglial activation: a confocal time-lapse analysis in hippocampal slices. Glia 33, 256 266.
    • (2001) Glia , vol.33 , pp. 256-266
    • Stence, N.1    Waite, M.2    Dailey, M.E.3
  • 40
    • 0036228048 scopus 로고    scopus 로고
    • The differential role of spinal MHC class II and cellular adhesion molecules in peripheral inflammatory versus neuropathic pain in rodents
    • Sweitzer S. M., White K. A., Dutta C. DeLeo J. A. (2002) The differential role of spinal MHC class II and cellular adhesion molecules in peripheral inflammatory versus neuropathic pain in rodents. J. Neuroimmunol. 125, 82 93.
    • (2002) J. Neuroimmunol. , vol.125 , pp. 82-93
    • Sweitzer, S.M.1    White, K.A.2    Dutta, C.3    Deleo, J.A.4
  • 41
    • 0347814979 scopus 로고    scopus 로고
    • Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain
    • Tanga F. Y., Raghavendra V. DeLeo J. A. (2004) Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain. Neurochem. Int. 45, 397 407.
    • (2004) Neurochem. Int. , vol.45 , pp. 397-407
    • Tanga, F.Y.1    Raghavendra, V.2    Deleo, J.A.3
  • 43
    • 0035876916 scopus 로고    scopus 로고
    • Minocycline provides neuroprotection against N-methyl-d-aspartate neurotoxicity by inhibiting microglia
    • Tikka T. M. Koistinaho J. E. (2001) Minocycline provides neuroprotection against N-methyl-d-aspartate neurotoxicity by inhibiting microglia. J. Immunol. 166, 7527 7533.
    • (2001) J. Immunol. , vol.166 , pp. 7527-7533
    • Tikka, T.M.1    Koistinaho, J.E.2
  • 44
    • 0035871840 scopus 로고    scopus 로고
    • Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
    • Tikka T., Fiebich B. L., Goldsteins G., Keinanen R. Koistinaho J. (2001) Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia. J. Neurosci. 21, 2580 2588.
    • (2001) J. Neurosci. , vol.21 , pp. 2580-2588
    • Tikka, T.1    Fiebich, B.L.2    Goldsteins, G.3    Keinanen, R.4    Koistinaho, J.5
  • 45
    • 34249714208 scopus 로고    scopus 로고
    • Age-related changes in the spinal cord microglial and astrocytic response profile to nerve injury
    • Vega-Avelaira D., Moss A. Fitzgerald M. (2007) Age-related changes in the spinal cord microglial and astrocytic response profile to nerve injury. Brain Behav. Immun. 21, 617 623.
    • (2007) Brain Behav. Immun. , vol.21 , pp. 617-623
    • Vega-Avelaira, D.1    Moss, A.2    Fitzgerald, M.3
  • 47
    • 0033836217 scopus 로고    scopus 로고
    • Phagocytic clearance of apoptotic neurons by microglia/brain macrophages in vitro: Involvement of lectin-, integrin-, and phosphatidylserine-mediated recognition
    • Witting A., Muller P., Herrmann A., Kettenmann H. Nolte C. (2000) Phagocytic clearance of apoptotic neurons by microglia/brain macrophages in vitro: involvement of lectin-, integrin-, and phosphatidylserine-mediated recognition. J. Neurochem. 75, 1060 1070.
    • (2000) J. Neurochem. , vol.75 , pp. 1060-1070
    • Witting, A.1    Muller, P.2    Herrmann, A.3    Kettenmann, H.4    Nolte, C.5
  • 48
    • 4143127785 scopus 로고    scopus 로고
    • Minocycline exerts multiple inhibitory effects on vascular endothelial growth factor-induced smooth muscle cell migration: The role of ERK1/2, PI3K, and matrix metalloproteinases
    • Yao J. S., Chen Y., Zhai W., Xu K., Young W. L. Yang G. Y. (2004) Minocycline exerts multiple inhibitory effects on vascular endothelial growth factor-induced smooth muscle cell migration: the role of ERK1/2, PI3K, and matrix metalloproteinases. Circ. Res. 95, 364 371.
    • (2004) Circ. Res. , vol.95 , pp. 364-371
    • Yao, J.S.1    Chen, Y.2    Zhai, W.3    Xu, K.4    Young, W.L.5    Yang, G.Y.6
  • 50
    • 33847337984 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase-regulated microglia-neuron signaling by prostaglandin E2 contributes to pain after spinal cord injury
    • Zhao P., Waxman S. G. Hains B. C. (2007) Extracellular signal-regulated kinase-regulated microglia-neuron signaling by prostaglandin E2 contributes to pain after spinal cord injury. J. Neurosci. 27, 2357 2368.
    • (2007) J. Neurosci. , vol.27 , pp. 2357-2368
    • Zhao, P.1    Waxman, S.G.2    Hains, B.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.