Minocycline reduces astrocytic reactivation and neuroinflammation in the hippocampus of a vascular cognitive impairment rat model

Neuroscience Bulletin

Volumn 26, Issue 1, 2010, Pages 28-36

  Cai, Zhi You ^a   Yan, Yong ^b   Chen, Ran ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Astrocyte; Inflammation; Minocycline; Vascular cognitive impairment

Indexed keywords

CYCLOOXYGENASE 2; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MINOCYCLINE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTROCYTE; BRAIN ISCHEMIA; CAROTID ARTERY OBSTRUCTION; CELL ACTIVATION; COGNITIVE DEFECT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOHISTOCHEMISTRY; NEUROPROTECTION; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SYNTHESIS INHIBITION; RAT; UPREGULATION; VASCULAR COGNITIVE IMPAIRMENT; WESTERN BLOTTING;

ANIMALS; ASTROCYTES; CAROTID ARTERY DISEASES; CAROTID ARTERY, COMMON; COGNITION DISORDERS; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; INTERLEUKIN-1BETA; MINOCYCLINE; NEUROPROTECTIVE AGENTS; NF-KAPPA B; RANDOM ALLOCATION; RATS; RATS, WISTAR; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 76649110556     PISSN: 16737067     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12264-010-0818-2     Document Type: Article

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