-
1
-
-
0038799991
-
Multiple pathways of recombination induced by double-strand breaks in Sacchammyces cerevisiae
-
Paques, F. and Haber, J. E. Multiple pathways of recombination induced by double-strand breaks in Sacchammyces cerevisiae. Microbiol. Mol. Biol. Rev., 63: 349-404, 1999.
-
(1999)
Microbiol. Mol. Biol. Rev.
, vol.63
, pp. 349-404
-
-
Paques, F.1
Haber, J.E.2
-
2
-
-
0033846527
-
The Rad51 paralog Rad51B promotes homologous recombinational repair
-
Takata, M., Sasaki, M. S., Sonoda, E., Fukushima, T., Morrison, C., Abala, J. S., Swagemakers, S. M. A., Kanaar, R., Thompson, L. H., and Takeda, S. The Rad51 paralog Rad51B promotes homologous recombinational repair. Mol. Cell. Biol., 20: 6476-6482, 2000.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 6476-6482
-
-
Takata, M.1
Sasaki, M.S.2
Sonoda, E.3
Fukushima, T.4
Morrison, C.5
Abala, J.S.6
Swagemakers, S.M.A.7
Kanaar, R.8
Thompson, L.H.9
Takeda, S.10
-
3
-
-
0035083172
-
Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs
-
Takata, M., Sasaki, M. S., Tachiiri, S., Fukushima, T., Sonoda, E., Schild, D., Thompson, L. H., and Takeda, S. Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs. Mol. Cell. Biol., 21: 2858-2866, 2001.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 2858-2866
-
-
Takata, M.1
Sasaki, M.S.2
Tachiiri, S.3
Fukushima, T.4
Sonoda, E.5
Schild, D.6
Thompson, L.H.7
Takeda, S.8
-
4
-
-
0033598437
-
Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination
-
Johnson, R. D., Liu, N., and Jasin, M. Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination. Nature, 401: 397-399, 1999.
-
(1999)
Nature
, vol.401
, pp. 397-399
-
-
Johnson, R.D.1
Liu, N.2
Jasin, M.3
-
5
-
-
0033569684
-
XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
-
Pierce, A. J., Johnson, R. D., Thompson, L. H., and Jasin, M. XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev., 13: 2633-2638, 1999.
-
(1999)
Genes Dev.
, vol.13
, pp. 2633-2638
-
-
Pierce, A.J.1
Johnson, R.D.2
Thompson, L.H.3
Jasin, M.4
-
6
-
-
0034689136
-
XRCC3 is required for efficient repair of chromosome breaks by homologous recombination
-
Brenneman, M. A., Weiss, A. E., Nickoloff, J. A., and Chen, D. J. XRCC3 is required for efficient repair of chromosome breaks by homologous recombination. Mutat. Res., 459: 89-97, 2000.
-
(2000)
Mutat. Res.
, vol.459
, pp. 89-97
-
-
Brenneman, M.A.1
Weiss, A.E.2
Nickoloff, J.A.3
Chen, D.J.4
-
7
-
-
0031741550
-
Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52
-
Yamaguchi-Iwai, Y., Sonoda, E., Buerstedde, J. M., Bezzubova, O., Morrison, C., Takata, M., Shinohara, A., and Takeda, S. Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52. Mol. Cell. Biol., 18: 6430-6435, 1998.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6430-6435
-
-
Yamaguchi-Iwai, Y.1
Sonoda, E.2
Buerstedde, J.M.3
Bezzubova, O.4
Morrison, C.5
Takata, M.6
Shinohara, A.7
Takeda, S.8
-
8
-
-
0033996037
-
Mouse RAD54 affects DNA double-strand break repair and sister chromatid exchange
-
Dronkert, M. L. G., Beverloo, H. B., Johnson, R. D., Hoeijmakers, J. H. J., Jasin, M., and Kanaar, R. Mouse RAD54 affects DNA double-strand break repair and sister chromatid exchange. Mol. Cell. Biol., 20: 3147-3156, 2000.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3147-3156
-
-
Dronkert, M.L.G.1
Beverloo, H.B.2
Johnson, R.D.3
Hoeijmakers, J.H.J.4
Jasin, M.5
Kanaar, R.6
-
9
-
-
0030930925
-
Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein
-
Bertrand, P., Rouillard, D., Boulet, A., Levalois, C., Soussi, T., and Lopez, B. S. Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein. Oncogene, 14: 1117-1122, 1997.
-
(1997)
Oncogene
, vol.14
, pp. 1117-1122
-
-
Bertrand, P.1
Rouillard, D.2
Boulet, A.3
Levalois, C.4
Soussi, T.5
Lopez, B.S.6
-
10
-
-
0030915139
-
Inactivation of p53 results in high-rates of homologous recombination
-
Mekeel, K. L., Tang, W., Kachnic, L. A., Luo, C. M., Defrank, J. S., and Powell, S. N. Inactivation of p53 results in high-rates of homologous recombination. Oncogene, 14: 1847-1857, 1997.
-
(1997)
Oncogene
, vol.14
, pp. 1847-1857
-
-
Mekeel, K.L.1
Tang, W.2
Kachnic, L.A.3
Luo, C.M.4
Defrank, J.S.5
Powell, S.N.6
-
11
-
-
0027306104
-
High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia
-
Meyn, M. S. High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia. Science, 260: 1327-1330, 1993.
-
(1993)
Science
, vol.260
, pp. 1327-1330
-
-
Meyn, M.S.1
-
12
-
-
0032803306
-
Replication protein A (RPA): The eukaryotic SSB
-
Iftode, C., Daniely, Y., and Borowiec, J. A. Replication protein A (RPA): the eukaryotic SSB. Crit. Rev. Biochem. Mol. Biol., 34: 141-180, 1999.
-
(1999)
Crit. Rev. Biochem. Mol. Biol.
, vol.34
, pp. 141-180
-
-
Iftode, C.1
Daniely, Y.2
Borowiec, J.A.3
-
13
-
-
0035099044
-
BRCA2 is required for homology-directed repair of chromosomal breaks
-
Moynahan, M. E., Pierce, A. J., and Jasin, M. BRCA2 is required for homology-directed repair of chromosomal breaks. Mol. Cell, 7: 263-272, 2001.2001. 2001.
-
(2001)
Mol. Cell
, vol.7
, pp. 263-272
-
-
Moynahan, M.E.1
Pierce, A.J.2
Jasin, M.3
-
14
-
-
0033213392
-
Brcal controls homology-directed DNA repair
-
Moynahan, M. E., Chiu, J. W., Koller, B. H., and Jasin, M. Brcal controls homology-directed DNA repair. Mol. Cell, 4: 511-518, 1999.
-
(1999)
Mol. Cell
, vol.4
, pp. 511-518
-
-
Moynahan, M.E.1
Chiu, J.W.2
Koller, B.H.3
Jasin, M.4
-
15
-
-
0000264268
-
The MREII-RAD50 complex: Diverse functions in the cellular DNA damage response
-
J. A. Nickoloff and M. F. Hoekstra (eds.). Totowa, NJ: Humana Press
-
Petrini, J. H. J., Maser, R. S., and Bressan, D. A. The MREII-RAD50 complex: diverse functions in the cellular DNA damage response. In: J. A. Nickoloff and M. F. Hoekstra (eds.), DNA Damage and Repair, Vol. III: Advances from Phage to Humans, pp. 147-172. Totowa, NJ: Humana Press, 2001.
-
(2001)
DNA Damage and Repair, Vol. III: Advances from Phage to Humans
, vol.3
, pp. 147-172
-
-
Petrini, J.H.J.1
Maser, R.S.2
Bressan, D.A.3
-
16
-
-
0003363869
-
BRCA1 and BRCA2 in DNA repair and genome stability
-
J. A. Nickoloff and M. F. Hoekstra (eds.). Totowa, NJ: Humana Press
-
Brenneman, M. A. BRCA1 and BRCA2 in DNA repair and genome stability. In: J. A. Nickoloff and M. F. Hoekstra (eds.), DNA Damage and Repair, Vol. 3: Advances from Phage to Humans, pp. 237-267. Totowa, NJ: Humana Press, 2001.
-
(2001)
DNA Damage and Repair, Volume 3: Advances from Phage to Humans
, vol.3
, pp. 237-267
-
-
Brenneman, M.A.1
-
17
-
-
0036671755
-
XRCC3 controls the fidelity of homologous recombination: Roles for XRCC3 in late stages of recombination
-
Brenneman, M. A., Wagener, B. M., Miller, C. A., Allen, C., and Nickoloff, J. A. XRCC3 controls the fidelity of homologous recombination: roles for XRCC3 in late stages of recombination. Mol. Cell, 10: 387-395, 2002.
-
(2002)
Mol. Cell
, vol.10
, pp. 387-395
-
-
Brenneman, M.A.1
Wagener, B.M.2
Miller, C.A.3
Allen, C.4
Nickoloff, J.A.5
-
18
-
-
0032860479
-
Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants
-
Chen, C. and Kolodner, R. D. Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat. Genet., 23: 81-85, 1999.
-
(1999)
Nat. Genet.
, vol.23
, pp. 81-85
-
-
Chen, C.1
Kolodner, R.D.2
-
19
-
-
0033576687
-
The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts
-
Karanjawala, Z. E., Grawunder, U., Hsieh, C. L., and Lieber, M. R. The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts. Curr. Biol., 9: 1501-1504, 1999.
-
(1999)
Curr. Biol.
, vol.9
, pp. 1501-1504
-
-
Karanjawala, Z.E.1
Grawunder, U.2
Hsieh, C.L.3
Lieber, M.R.4
-
20
-
-
0034612308
-
The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations
-
Ferguson, D. O., Sekiguchi, J. M., Chang, S., Frank, K. M., Gao, Y. J., DePinho, R. A., and Alt, F. W. The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations. Proc. Natl. Acad. Sci. USA, 97: 6630-6633, 2000.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6630-6633
-
-
Ferguson, D.O.1
Sekiguchi, J.M.2
Chang, S.3
Frank, K.M.4
Gao, Y.J.5
DePinho, R.A.6
Alt, F.W.7
-
21
-
-
0037019597
-
The Greek goddess, Artemis, reveals the secrets of her cleavage
-
Jeggo, P. A. and O'Neill, P. The Greek goddess, Artemis, reveals the secrets of her cleavage. DNA Repair, 1: 771-777, 2002.
-
(2002)
DNA Repair
, vol.1
, pp. 771-777
-
-
Jeggo, P.A.1
O'Neill, P.2
-
22
-
-
0036261707
-
Sensing and repairing DNA double-strand breaks
-
Jackson, S. P. Sensing and repairing DNA double-strand breaks. Carcinogenesis, 23: 687-696, 2002.
-
(2002)
Carcinogenesis
, vol.23
, pp. 687-696
-
-
Jackson, S.P.1
-
23
-
-
0035851181
-
Wemer syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase
-
Yannone, S. M., Roy, S., Chan, D. W., Murphy, M. B., Huang, S. R., Campisi, J., and Chen, D. J. Wemer syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase. J. Biol. Chem., 276: 38242-38248, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38242-38248
-
-
Yannone, S.M.1
Roy, S.2
Chan, D.W.3
Murphy, M.B.4
Huang, S.R.5
Campisi, J.6
Chen, D.J.7
-
24
-
-
0037022639
-
Interferon regulatory factor-3 is an in vivo target of DNA-PK
-
Karpova, A. Y., Trost, M., Murray, J. M., Cantley, L. C., and Howley, P. M. Interferon regulatory factor-3 is an in vivo target of DNA-PK. Proc. Natl. Acad. Sci. USA, 99: 2818-2823, 2002.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 2818-2823
-
-
Karpova, A.Y.1
Trost, M.2
Murray, J.M.3
Cantley, L.C.4
Howley, P.M.5
-
25
-
-
2242484657
-
Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase
-
Douglas, P., Sapkota, G. P., Morrice, N., Yu, Y. P., Goodarzi, A. A., Merkle, D., Meek, K., Alessi, D. R., and Lees-Miller, S. P. Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase. Biochem. J., 368: 243-251, 2002.
-
(2002)
Biochem. J.
, vol.368
, pp. 243-251
-
-
Douglas, P.1
Sapkota, G.P.2
Morrice, N.3
Yu, Y.P.4
Goodarzi, A.A.5
Merkle, D.6
Meek, K.7
Alessi, D.R.8
Lees-Miller, S.P.9
-
26
-
-
0030009738
-
The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit
-
Chan, D. W. and Lees-Miller, S. P. The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit. J. Biol. Chem., 271: 8936-8941, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 8936-8941
-
-
Chan, D.W.1
Lees-Miller, S.P.2
-
27
-
-
0037106180
-
Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks
-
Chan, D. W., Chen, B. P-C., Prithivirasingh, S., Kurimasa, A., Story, M. D., Qin, J., and Chen, D. J. Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks. Genes Dev., 16: 2333-2338, 2002.
-
(2002)
Genes Dev.
, vol.16
, pp. 2333-2338
-
-
Chan, D.W.1
Chen, B.P.-C.2
Prithivirasingh, S.3
Kurimasa, A.4
Story, M.D.5
Qin, J.6
Chen, D.J.7
-
28
-
-
0037159220
-
The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation
-
Merkle, D., Douglas, P., Moorhead, G. B. G., Leonenko, Z., Yu, Y., Cramb, D., Bazett-Jones, D. P., and Lees-Miller, S. P. The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation. Biochemistry, 41: 12706-12714, 2002.
-
(2002)
Biochemistry
, vol.41
, pp. 12706-12714
-
-
Merkle, D.1
Douglas, P.2
Moorhead, G.B.G.3
Leonenko, Z.4
Yu, Y.5
Cramb, D.6
Bazett-Jones, D.P.7
Lees-Miller, S.P.8
-
29
-
-
0035374588
-
Protein phosphatases regulate DNA-dependent protein kinase activity
-
Douglas, P., Moorhead, G. B. G., Ye, R. Q., and Lees-Miller, S. P. Protein phosphatases regulate DNA-dependent protein kinase activity. J. Biol. Chem., 276: 18992-18998, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18992-18998
-
-
Douglas, P.1
Moorhead, G.B.G.2
Ye, R.Q.3
Lees-Miller, S.P.4
-
30
-
-
0037133699
-
DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination
-
Allen, C., Kurimasa, A., Brennemann, M. A., Chen, D. J., and Nickoloff, J. A. DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination. Proc. Natl. Acad. Sci. USA, 99: 3758-3763, 2002.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3758-3763
-
-
Allen, C.1
Kurimasa, A.2
Brennemann, M.A.3
Chen, D.J.4
Nickoloff, J.A.5
-
31
-
-
0036682122
-
An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells
-
Delacote, F., Han, M., Stamato, T. D., Jasin, M., and Lopez, B. S. An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells. Nucleic Acids Res., 30: 3454-3463, 2002.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 3454-3463
-
-
Delacote, F.1
Han, M.2
Stamato, T.D.3
Jasin, M.4
Lopez, B.S.5
-
32
-
-
0034599981
-
Homologous and non-homologous recombination differentially affect DNA damage repair in mice
-
Essers, J., van Steeg, H., de Wit, J., Swagemakers, S. M. A., Vermeij, M., Hoeijmakers, J. H. J., and Kanaar, R. Homologous and non-homologous recombination differentially affect DNA damage repair in mice. EMBO J., 19: 1703-1710, 2000.
-
(2000)
EMBO J.
, vol.19
, pp. 1703-1710
-
-
Essers, J.1
Van Steeg, H.2
De Wit, J.3
Swagemakers, S.M.A.4
Vermeij, M.5
Hoeijmakers, J.H.J.6
Kanaar, R.7
-
33
-
-
0036864626
-
Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination
-
Frank-Vaillant, M. and Marcand, S. Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination. Mol. Cell, 10: 1189-1199, 2002.
-
(2002)
Mol. Cell
, vol.10
, pp. 1189-1199
-
-
Frank-Vaillant, M.1
Marcand, S.2
-
34
-
-
0035893363
-
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells
-
Pierce, A. J., Hu, P., Han, M. G., Ellis, N., and Jasin, M. Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. Genes Dev., 15: 3237-3242, 2001.
-
(2001)
Genes Dev.
, vol.15
, pp. 3237-3242
-
-
Pierce, A.J.1
Hu, P.2
Han, M.G.3
Ellis, N.4
Jasin, M.5
-
35
-
-
0032530658
-
Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
-
Takata, M., Sasaki, M. S., Sonoda, E., Morrison, C., Hashimoto, M., Utsumi, H., Yamaguchi-Iwai, Y., Shinohara, A., and Takeda, S. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. EMBO J., 17: 5497-5508, 1998.
-
(1998)
EMBO J.
, vol.17
, pp. 5497-5508
-
-
Takata, M.1
Sasaki, M.S.2
Sonoda, E.3
Morrison, C.4
Hashimoto, M.5
Utsumi, H.6
Yamaguchi-Iwai, Y.7
Shinohara, A.8
Takeda, S.9
-
36
-
-
0030779879
-
Chromosomal double-strand breaks induce gene conversion at high frequency in mammalian cells
-
Taghian, D. G. and Nickoloff, J. A. Chromosomal double-strand breaks induce gene conversion at high frequency in mammalian cells. Mol. Cell. Biol., 17: 6386-6393, 1997.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 6386-6393
-
-
Taghian, D.G.1
Nickoloff, J.A.2
-
37
-
-
0035504929
-
Overexpression of human RAD51 and RAD52 reduces double-strand break-induced homologous recombination in mammalian cells
-
Kim, P. M., Allen, C., Wagener, B. M., Shen, Z., and Nickoloff, J. A. Overexpression of human RAD51 and RAD52 reduces double-strand break-induced homologous recombination in mammalian cells. Nucleic Acids Res., 29: 4352-4360, 2001.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 4352-4360
-
-
Kim, P.M.1
Allen, C.2
Wagener, B.M.3
Shen, Z.4
Nickoloff, J.A.5
-
38
-
-
0032938747
-
Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining
-
Kurimasa, A., Kumano, S., Boubnov, N. V., Story, M. D., Tung, C. S., Peterson, S. R., and Chen, D. J. Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining. Mol. Cell. Biol., 19: 3877-3884, 1999.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3877-3884
-
-
Kurimasa, A.1
Kumano, S.2
Boubnov, N.V.3
Story, M.D.4
Tung, C.S.5
Peterson, S.R.6
Chen, D.J.7
-
39
-
-
0028902932
-
Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells
-
Peterson, S. R., Kurimasa, A., Oshimura, M., Dynan, W. S., Bradbury, E. M., and Chen, D. J. Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells. Proc. Natl. Acad. Sci. USA, 92: 3171-3174, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3171-3174
-
-
Peterson, S.R.1
Kurimasa, A.2
Oshimura, M.3
Dynan, W.S.4
Bradbury, E.M.5
Chen, D.J.6
-
40
-
-
0032916940
-
Wortmanin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks
-
Chernikova, S. B., Wells, R. L., and Elkind, M. M. Wortmanin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks. Radiat. Res., 151: 159-166, 1999.
-
(1999)
Radiat. Res.
, vol.151
, pp. 159-166
-
-
Chernikova, S.B.1
Wells, R.L.2
Elkind, M.M.3
-
41
-
-
0345404241
-
Differential inhibitory effect of OK-1035 on DNA repair in L5178Y murine lymphoma sublines with functional or defective repair of double strand breaks
-
Kruszewski, M., Wojewodzka, M., Iwanenko, T., Szumiel, I., and Okuyama, A. Differential inhibitory effect of OK-1035 on DNA repair in L5178Y murine lymphoma sublines with functional or defective repair of double strand breaks. Mutat. Res., 409: 31-36, 1998.
-
(1998)
Mutat. Res.
, vol.409
, pp. 31-36
-
-
Kruszewski, M.1
Wojewodzka, M.2
Iwanenko, T.3
Szumiel, I.4
Okuyama, A.5
-
42
-
-
0036827964
-
A targeted inhibition of DNA-dependent protein kinase sensitizes breast cancer cells following ionizing radiation
-
Kim, C-H., Park, S-J., and Lee, S-H. A targeted inhibition of DNA-dependent protein kinase sensitizes breast cancer cells following ionizing radiation. J. Pharmacol. Exp. Ther., 303: 753-759, 2002.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.303
, pp. 753-759
-
-
Kim, C.-H.1
Park, S.-J.2
Lee, S.-H.3
-
43
-
-
2642567204
-
DNA-PK inhibitors as drug candidates for the treatment of cancer
-
in press
-
Kashishian, A., Douangpanya, H., Clark, D., Schlachter, S., Eary, T., Schiro, J., Huang, H., Burgess, L., Kesicki, E. A., and Halbrook, J. DNA-PK inhibitors as drug candidates for the treatment of cancer. Mol. Cancer Ther., in press, 2003.
-
(2003)
Mol. Cancer Ther.
-
-
Kashishian, A.1
Douangpanya, H.2
Clark, D.3
Schlachter, S.4
Eary, T.5
Schiro, J.6
Huang, H.7
Burgess, L.8
Kesicki, E.A.9
Halbrook, J.10
-
44
-
-
0029833721
-
Chromosomal double-strand break repair in Ku80-deficient cells
-
Liang, F., Romanienko, P. J., Weaver, D. T., Jeggo, P. A., and Jasin, M. Chromosomal double-strand break repair in Ku80-deficient cells. Proc. Natl. Acad. Sci. USA, 93: 8929-8933, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8929-8933
-
-
Liang, F.1
Romanienko, P.J.2
Weaver, D.T.3
Jeggo, P.A.4
Jasin, M.5
-
45
-
-
0030682172
-
DNA-dependent protein-kinase
-
Jackson, S. P. DNA-dependent protein-kinase. Int. J. Biochem. Cell Biol., 29: 935-938, 1997.
-
(1997)
Int. J. Biochem. Cell Biol.
, vol.29
, pp. 935-938
-
-
Jackson, S.P.1
-
46
-
-
0032189483
-
Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin
-
Sarkaria, J. N., Tibbetts, R. S., Busby, E. C., Kennedy, A. P., Hill, D. E., and Abraham, R. T. Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin. Cancer Res., 58: 4375-4382, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 4375-4382
-
-
Sarkaria, J.N.1
Tibbetts, R.S.2
Busby, E.C.3
Kennedy, A.P.4
Hill, D.E.5
Abraham, R.T.6
-
47
-
-
0031765340
-
A phosphatidylinositol 3-kinase inhibitor wortmannin induces radioresistant DNA synthesis and sensitizes cells to bleomycin and ionizing radiation
-
Hosoi, Y., Miyachi, H., Matsumoto, Y., Ikehata, H., Komura, J., Ishii, K., Zhao, H. J., Yoshida, M., Takai, Y., Yamada, S., Suzuki, N., and Ono, T. A phosphatidylinositol 3-kinase inhibitor wortmannin induces radioresistant DNA synthesis and sensitizes cells to bleomycin and ionizing radiation. Int. J. Cancer. 78: 642-647, 1998.
-
(1998)
Int. J. Cancer
, vol.78
, pp. 642-647
-
-
Hosoi, Y.1
Miyachi, H.2
Matsumoto, Y.3
Ikehata, H.4
Komura, J.5
Ishii, K.6
Zhao, H.J.7
Yoshida, M.8
Takai, Y.9
Yamada, S.10
Suzuki, N.11
Ono, T.12
-
48
-
-
0034141562
-
The controlling role of ATM in homologous recombinational repair of DNA damage
-
Morrison, C., Sonoda, E., Takao, N., Shinohara, A., Yamamoto, K., and Takeda, S. The controlling role of ATM in homologous recombinational repair of DNA damage. EMBO J., 19: 463-471, 2000.
-
(2000)
EMBO J.
, vol.19
, pp. 463-471
-
-
Morrison, C.1
Sonoda, E.2
Takao, N.3
Shinohara, A.4
Yamamoto, K.5
Takeda, S.6
-
49
-
-
0030048511
-
High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines
-
Luo, C-M., Tang, W., Mekeel, K. L., DeFrank, J. S., Anne, P. R., and Powell, S. N. High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines. J. Biol. Chem., 271: 4497-4503, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4497-4503
-
-
Luo, C.-M.1
Tang, W.2
Mekeel, K.L.3
DeFrank, J.S.4
Anne, P.R.5
Powell, S.N.6
-
50
-
-
0033617368
-
Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl
-
Chen, G., Yuan, S. S., Liu, W., Xu, Y., Trujillo, K., Song, B., Cong, F., Goff, S. P., Wu, Y., Arlinghaus, R., Baltimore, D., Gasser, P. J., Park, M. S., Sung, P., and Lee, E. Y. Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl. J. Biol. Chem., 274: 12748-12752, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12748-12752
-
-
Chen, G.1
Yuan, S.S.2
Liu, W.3
Xu, Y.4
Trujillo, K.5
Song, B.6
Cong, F.7
Goff, S.P.8
Wu, Y.9
Arlinghaus, R.10
Baltimore, D.11
Gasser, P.J.12
Park, M.S.13
Sung, P.14
Lee, E.Y.15
-
51
-
-
0033954246
-
Replication fork pausing and recombination or "gimme a break"
-
Rothstein, R., Michel, B., and Gangloff, S. Replication fork pausing and recombination or "gimme a break". Genes Dev., 14: 1-10, 2000.
-
(2000)
Genes Dev.
, vol.14
, pp. 1-10
-
-
Rothstein, R.1
Michel, B.2
Gangloff, S.3
-
52
-
-
0031025093
-
DNA double-strand breaks caused by replication arrest
-
Michel, B., Ehrlich, S. D., and Uzest, M. DNA double-strand breaks caused by replication arrest. EMBO J., 16: 430-438, 1997.
-
(1997)
EMBO J.
, vol.16
, pp. 430-438
-
-
Michel, B.1
Ehrlich, S.D.2
Uzest, M.3
-
53
-
-
0030737725
-
Stable DNA replication: Interplay between DNA replication, homologous recombination, and transcription
-
Kogoma, T. Stable DNA replication: interplay between DNA replication, homologous recombination, and transcription. Microbiol. Mol. Biol. Rev., 61: 212-238, 1997.
-
(1997)
Microbiol. Mol. Biol. Rev.
, vol.61
, pp. 212-238
-
-
Kogoma, T.1
-
54
-
-
0021827069
-
Relative rates of homologous and nonhomologous recombination in transfected DNA
-
Roth, D. and Wilson, J. H. Relative rates of homologous and nonhomologous recombination in transfected DNA. Proc. Natl. Acad. Sci. USA, 82: 3355-3359, 1985.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 3355-3359
-
-
Roth, D.1
Wilson, J.H.2
-
55
-
-
0032127849
-
Role of the human RAD51 protein in homologous recombination and double-stranded break repair
-
Baumann, P. and West, S. C. Role of the human RAD51 protein in homologous recombination and double-stranded break repair. Trends Biochem. Sci., 23: 247-251, 1998.
-
(1998)
Trends Biochem. Sci.
, vol.23
, pp. 247-251
-
-
Baumann, P.1
West, S.C.2
-
56
-
-
0034195218
-
Partners and pathways: Repairing a double-strand break
-
Haber, J. E. Partners and pathways: repairing a double-strand break. Trends Biochem. Sci., 16: 259-264, 2000.
-
(2000)
Trends Biochem. Sci.
, vol.16
, pp. 259-264
-
-
Haber, J.E.1
-
57
-
-
0035105722
-
Homologous recombinational repair of double-strand breaks in yeast is enhanced by MAT heterozygosity through yKu-dependent and -independent mechanisms
-
Clikeman, J. A., Khalsa, G. J., Barton, S. L., and Nickoloff, J. A. Homologous recombinational repair of double-strand breaks in yeast is enhanced by MAT heterozygosity through yKu-dependent and -independent mechanisms. Genetics, 157: 579-589, 2001.
-
(2001)
Genetics
, vol.157
, pp. 579-589
-
-
Clikeman, J.A.1
Khalsa, G.J.2
Barton, S.L.3
Nickoloff, J.A.4
-
58
-
-
0032567041
-
The many interfaces of mrel1
-
Haber, J. E. The many interfaces of mrel1. Cell, 95: 583-586, 1998.
-
(1998)
Cell
, vol.95
, pp. 583-586
-
-
Haber, J.E.1
-
59
-
-
0012173355
-
Recombination: Mechanisms and roles in tumorigenesis
-
J. R. Bertino (ed.). San Diego: Elsevier Science (USA)
-
Nickoloff, J. A. Recombination: mechanisms and roles in tumorigenesis. In: J. R. Bertino (ed.), Encyclopedia of Cancer, 2nd edn., Vol. 4, pp. 49-59. San Diego: Elsevier Science (USA), 2002.
-
(2002)
Encyclopedia of Cancer, 2nd Edn.
, vol.4
, pp. 49-59
-
-
Nickoloff, J.A.1
-
60
-
-
0035871341
-
Loss of Werner syndrome protein function promotes aberrant mitotic recombination
-
Prince, P. R., Emond, M. J., and Monnat, R. J. Loss of Werner syndrome protein function promotes aberrant mitotic recombination. Genes Dev., 15: 933-938, 2001.
-
(2001)
Genes Dev.
, vol.15
, pp. 933-938
-
-
Prince, P.R.1
Emond, M.J.2
Monnat, R.J.3
-
61
-
-
0034655912
-
Ku complex interacts with and stimulates the Werner protein
-
Cooper, M. P., Machwe, A., Orren, D. K., Borsh, R. M., Ramsden, D., and Bohr, V. A. Ku complex interacts with and stimulates the Werner protein. Genes Dev., 14: 907-912, 2000.
-
(2000)
Genes Dev.
, vol.14
, pp. 907-912
-
-
Cooper, M.P.1
Machwe, A.2
Orren, D.K.3
Borsh, R.M.4
Ramsden, D.5
Bohr, V.A.6
-
62
-
-
0034665971
-
Functional interaction between Ku and the Werner syndrome protein in DNA end processing
-
Li, B. M. and Comai, L. Functional interaction between Ku and the Werner syndrome protein in DNA end processing. J. Biol. Chem., 275: 28349-28352, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28349-28352
-
-
Li, B.M.1
Comai, L.2
-
63
-
-
0035971076
-
Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex
-
Li, B. M. and Comai, L. Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex. J. Biol. Chem., 276: 9896-9902, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9896-9902
-
-
Li, B.M.1
Comai, L.2
-
64
-
-
0030733163
-
Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions
-
Jin, S. F. and Weaver, D. T. Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions. EMBO J., 16: 6874-6885, 1997.
-
(1997)
EMBO J.
, vol.16
, pp. 6874-6885
-
-
Jin, S.F.1
Weaver, D.T.2
-
65
-
-
0029954821
-
Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae
-
Milne, G. T., Jin, S., Shannon, K. B., and Weaver, D. T. Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol. Cell. Biol., 16: 4189-4198, 1996.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4189-4198
-
-
Milne, G.T.1
Jin, S.2
Shannon, K.B.3
Weaver, D.T.4
-
66
-
-
0032721091
-
The Mrel1-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae
-
Bressan, D. A., Baxter, B. K., and Petrini, J. H. J. The Mrel1-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae. Mol. Cell. Biol., 19: 7681-7687, 1999.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 7681-7687
-
-
Bressan, D.A.1
Baxter, B.K.2
Petrini, J.H.J.3
-
67
-
-
0035977007
-
Genetic analysis of the DNA-dependent protein kinase reveals an inhibitory role of Ku in late S-G(2) phase DNA double-strand break repair
-
Fukushima, T., Takata, M., Morrison, C., Araki, R., Fujimori, A., Abe, M., Tatsumi, K., Jasin, M., Dhar, P. K., Sonoda, E., Chiba, T., and Takeda, S. Genetic analysis of the DNA-dependent protein kinase reveals an inhibitory role of Ku in late S-G(2) phase DNA double-strand break repair. J. Biol. Chem., 276: 44413-44418, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44413-44418
-
-
Fukushima, T.1
Takata, M.2
Morrison, C.3
Araki, R.4
Fujimori, A.5
Abe, M.6
Tatsumi, K.7
Jasin, M.8
Dhar, P.K.9
Sonoda, E.10
Chiba, T.11
Takeda, S.12
-
68
-
-
0035834067
-
DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair
-
Adachi, N., Ishino, T., Ishii, Y., Takeda, S., and Koyama, H. DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: implications for DNA double-strand break repair. Proc. Natl. Acad. Sci. USA, 98: 12109-12113, 2001.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12109-12113
-
-
Adachi, N.1
Ishino, T.2
Ishii, Y.3
Takeda, S.4
Koyama, H.5
-
69
-
-
0033583204
-
The DNA-dependent protein kinase catalytic activity regulates DNA end processing by means of Ku entry into DNA
-
Calsou, P., Frit, P., Humbert, O., Muller, C., Chen, D. J., and Salles, B. The DNA-dependent protein kinase catalytic activity regulates DNA end processing by means of Ku entry into DNA. J. Biol. Chem., 274: 7848-7856, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7848-7856
-
-
Calsou, P.1
Frit, P.2
Humbert, O.3
Muller, C.4
Chen, D.J.5
Salles, B.6
-
70
-
-
0026687883
-
Human DNA-activated protein kinase phosphorylates serine 15 and 37 in the amino terminal transactivation domain of human p53
-
Lees-Miller, S. P., Sakaguchi, K., Ullrich, S., Appella, E., and Anderson, C. W. Human DNA-activated protein kinase phosphorylates serine 15 and 37 in the amino terminal transactivation domain of human p53. Mol. Cell. Biol., 12: 5041-5049, 1992.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 5041-5049
-
-
Lees-Miller, S.P.1
Sakaguchi, K.2
Ullrich, S.3
Appella, E.4
Anderson, C.W.5
-
71
-
-
0028897304
-
DNA-dependent protein kinase activity is absent in xrs-6 cells: Implications for site-specific recombination and DNA double-strand break repair
-
Finnie, N. J., Gottlieb, T. M., Blunt, T., Jeggo, P. A., and Jackson, S. P. DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair. Proc. Natl. Acad. Sci. USA, 92: 320-324, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 320-324
-
-
Finnie, N.J.1
Gottlieb, T.M.2
Blunt, T.3
Jeggo, P.A.4
Jackson, S.P.5
-
72
-
-
0000391880
-
Evidence for DNA-PK-dependent and DNA-PK-independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle
-
Lee, S. E., Mitchell, R. A., Cheng, A., and Hendrickson, E. A. Evidence for DNA-PK-dependent and DNA-PK-independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle. Mol. Cell. Biol., 17: 1425-1433, 1997.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1425-1433
-
-
Lee, S.E.1
Mitchell, R.A.2
Cheng, A.3
Hendrickson, E.A.4
-
73
-
-
0028919608
-
Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae
-
Choulika, A., Perrin, A., Dujon, B., and Nicolas, J-F. Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae. Mol. Cell. Biol., 15: 1968-1973, 1995.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 1968-1973
-
-
Choulika, A.1
Perrin, A.2
Dujon, B.3
Nicolas, J.-F.4
|