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Volumn 18, Issue 10, 1998, Pages 5908-5920

Productive and nonproductive complexes of Ku and DNA-dependent protein kinase at DNA termini

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PROTEIN KINASE;

EID: 0031708232     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.18.10.5908     Document Type: Article
Times cited : (149)

References (42)
  • 1
    • 0030420088 scopus 로고    scopus 로고
    • The DNA-activated protein kinase-DNA-PK
    • R. Jessberger and M. R. Lieber (ed.). Springer-Verlag, Heidelberg, Germany
    • Anderson, C. W., and T. H. Carter. 1996. The DNA-activated protein kinase-DNA-PK, p. 91-112. In R. Jessberger and M. R. Lieber (ed.), Molecular analysis of DNA rearrangements in the immune system. Springer-Verlag, Heidelberg, Germany.
    • (1996) Molecular Analysis of DNA Rearrangements in the Immune System , pp. 91-112
    • Anderson, C.W.1    Carter, T.H.2
  • 4
    • 0028607553 scopus 로고
    • The DNA-activated protein kinase is required for the phosphorylation of replication protein A during SV40 DNA replication
    • Brush, G., C. W. Anderson, and T. J. Kelly. 1994. The DNA-activated protein kinase is required for the phosphorylation of replication protein A during SV40 DNA replication. Proc. Natl. Acad. Sci. USA 91:12520-12524.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12520-12524
    • Brush, G.1    Anderson, C.W.2    Kelly, T.J.3
  • 7
    • 0030009738 scopus 로고    scopus 로고
    • The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit
    • Chan, D. W., and S. P. Lees-Miller. 1996. The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit. J. Biol. Chem. 271:8936-8941.
    • (1996) J. Biol. Chem. , vol.271 , pp. 8936-8941
    • Chan, D.W.1    Lees-Miller, S.P.2
  • 8
    • 0030367822 scopus 로고    scopus 로고
    • Purification and characterization of the double-stranded DNA-activated protein kinase, DNA-PK, from human placenta
    • Chan, D. W., C. H. Mody, N. S. Ting, and S. P. Lees-Miller. 1996. Purification and characterization of the double-stranded DNA-activated protein kinase, DNA-PK, from human placenta. Biochem. Cell Biol. 74:67-73.
    • (1996) Biochem. Cell Biol. , vol.74 , pp. 67-73
    • Chan, D.W.1    Mody, C.H.2    Ting, N.S.3    Lees-Miller, S.P.4
  • 9
    • 0031214080 scopus 로고    scopus 로고
    • Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV
    • Critchlow, S., R. Bowater, and S. P. Jackson. 1997. Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV. Curr. Biol. 7:588-598.
    • (1997) Curr. Biol. , vol.7 , pp. 588-598
    • Critchlow, S.1    Bowater, R.2    Jackson, S.P.3
  • 10
    • 0024356877 scopus 로고
    • HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex
    • deVries, E., W. van Driel, W. G. Bergsma, A. C. Arnberg, and P. C. van den Vliet. 1989. HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex. J. Mol. Biol. 208:65-78.
    • (1989) J. Mol. Biol. , vol.208 , pp. 65-78
    • DeVries, E.1    Van Driel, W.2    Bergsma, W.G.3    Arnberg, A.C.4    Van den Vliet, P.C.5
  • 11
    • 0027246193 scopus 로고
    • Purification and characterization of a template-associated protein kinase that phosphorylates RNA polymerase II
    • Dvir, A., L. Y. Stein, B. L. Calore, and W. S. Dynan. 1993. Purification and characterization of a template-associated protein kinase that phosphorylates RNA polymerase II. J. Biol. Chem. 268:10440-10447.
    • (1993) J. Biol. Chem. , vol.268 , pp. 10440-10447
    • Dvir, A.1    Stein, L.Y.2    Calore, B.L.3    Dynan, W.S.4
  • 12
    • 0027156140 scopus 로고
    • EBP-80, a transcription factor closely resembling the human autoantigcn Ku, recognizes single- to double-strand transitions in DNA
    • Falzon, M., J. Fewell, and E. L. Kuff. 1993. EBP-80, a transcription factor closely resembling the human autoantigcn Ku, recognizes single-to double-strand transitions in DNA. J. Biol. Chem. 268:10546-10552.
    • (1993) J. Biol. Chem. , vol.268 , pp. 10546-10552
    • Falzon, M.1    Fewell, J.2    Kuff, E.L.3
  • 13
    • 0028897304 scopus 로고
    • DNA-dependent protein kinase activity is absent in xrs-6 cells: Implications for site-specific recombination and DNA double-strand break repair
    • Finnic, N. J., T. Gottlieb, T. Blunt, P. Jeggo, and S. P. Jackson. 1995. DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair. Proc. Natl. Acad. Sci. USA 92:320-324.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 320-324
    • Finnic, N.J.1    Gottlieb, T.2    Blunt, T.3    Jeggo, P.4    Jackson, S.P.5
  • 14
    • 0028269682 scopus 로고
    • Real-time DNA binding measurements of the ETSL recombinant oncoproteins reveal significant kinetic differences between the p42 and p51 isoforms
    • Fisher, R. J., M. Fluach, J. Casa-Finet, J. W. Erckson, A. Kondoh, S. Bladen, C. Fishewr, D. Watson, and T. Papas. 1994. Real-time DNA binding measurements of the ETSL recombinant oncoproteins reveal significant kinetic differences between the p42 and p51 isoforms. Protein Sci. 3:257-266.
    • (1994) Protein Sci. , vol.3 , pp. 257-266
    • Fisher, R.J.1    Fluach, M.2    Casa-Finet, J.3    Erckson, J.W.4    Kondoh, A.5    Bladen, S.6    Fishewr, C.7    Watson, D.8    Papas, T.9
  • 15
    • 0022348695 scopus 로고
    • Cell cycle-dependent repair of double-strand DNA breaks in a gamma-ray-sensitive Chinese hamster cell
    • Giaccia, A., R. Weinstein, J. Hu, and T. D. Stamato. 1985. Cell cycle-dependent repair of double-strand DNA breaks in a gamma-ray-sensitive Chinese hamster cell. Somatic Cell Mol. Genet. 11:485-491.
    • (1985) Somatic Cell Mol. Genet. , vol.11 , pp. 485-491
    • Giaccia, A.1    Weinstein, R.2    Hu, J.3    Stamato, T.D.4
  • 16
    • 0027397867 scopus 로고
    • The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
    • Gottlieb, T., and S. P. Jackson. 1993. The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 72:131-42.
    • (1993) Cell , vol.72 , pp. 131-142
    • Gottlieb, T.1    Jackson, S.P.2
  • 17
    • 0030743386 scopus 로고    scopus 로고
    • Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
    • Grawunder, U., M. Wilm, X. Wu, P. Kulesza, T. E. Wilson, M. Mann, and M. R. Lieber. 1997. Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature 388:492-495.
    • (1997) Nature , vol.388 , pp. 492-495
    • Grawunder, U.1    Wilm, M.2    Wu, X.3    Kulesza, P.4    Wilson, T.E.5    Mann, M.6    Lieber, M.R.7
  • 18
    • 0030858967 scopus 로고    scopus 로고
    • Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination
    • Gu, Y., S. Jin, Y. Gao, D. T. Weaver, and F. W. Alt. 1997. Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination. Proc. Natl. Acad. Sci. USA 94:8076-8081.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8076-8081
    • Gu, Y.1    Jin, S.2    Gao, Y.3    Weaver, D.T.4    Alt, F.W.5
  • 19
    • 0031930488 scopus 로고    scopus 로고
    • DNA-dependent protein kinase: DNA binding and activation in the absence of Ku
    • Hammarsten, O., and G. Chu. 1998. DNA-dependent protein kinase: DNA binding and activation in the absence of Ku. Proc. Natl. Acad. Sci. USA 95:525-530.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 525-530
    • Hammarsten, O.1    Chu, G.2
  • 20
    • 0030021296 scopus 로고    scopus 로고
    • The recognition of DNA damage
    • Jackson, S. P. 1996. The recognition of DNA damage. Curr. Opin. Genet. Dev. 6:19-25.
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 19-25
    • Jackson, S.P.1
  • 21
    • 0028791446 scopus 로고
    • DNA double-strand break repair and V(D)J recombination: Involvement of DNA-PK
    • Jackson, S. P., and P. A. Jeggo. 1995. DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK. Trends Biochem. Sci. 20:412-415.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 412-415
    • Jackson, S.P.1    Jeggo, P.A.2
  • 24
    • 0024999553 scopus 로고
    • Purification and characterization of proximal sequence element-binding protein 1, a transcription activating protein related to Ku and TREF that binds the proximal sequence element of the human U1 promoter
    • Knuth, M. W., S. I. Gunderson, N. E. Thompson, L. A. Strasheim, and R. R. Burgess. 1990. Purification and characterization of proximal sequence element-binding protein 1, a transcription activating protein related to Ku and TREF that binds the proximal sequence element of the human U1 promoter. J. Biol. Chem. 265:17911-17920.
    • (1990) J. Biol. Chem. , vol.265 , pp. 17911-17920
    • Knuth, M.W.1    Gunderson, S.I.2    Thompson, N.E.3    Strasheim, L.A.4    Burgess, R.R.5
  • 25
    • 85038544966 scopus 로고    scopus 로고
    • DNA-PK is essential only for coding joint formation in V(D)J recombination
    • in press
    • Kulesza, P., and M. R. Lieber. DNA-PK is essential only for coding joint formation in V(D)J recombination. Nucleic Acids Res., in press.
    • Nucleic Acids Res.
    • Kulesza, P.1    Lieber, M.R.2
  • 26
    • 0025224761 scopus 로고
    • Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen
    • Lees-Miller, S. P., Y.-R. Chen, and C. W. Anderson. 1990. Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen. Mol. Cell. Biol. 10:6472-6481.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 6472-6481
    • Lees-Miller, S.P.1    Chen, Y.-R.2    Anderson, C.W.3
  • 27
    • 0026687883 scopus 로고
    • Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53
    • Lees-Miller, S. P., K. Sakaguchi, S. J. Ullrich, E. Appella, and C. W. Anderson. 1992. Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. Mol. Cell. Biol. 12:5041-5049.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 5041-5049
    • Lees-Miller, S.P.1    Sakaguchi, K.2    Ullrich, S.J.3    Appella, E.4    Anderson, C.W.5
  • 28
    • 0031059531 scopus 로고    scopus 로고
    • Tying loose ends: Roles of Ku and DNA-dependent protein kinase in the repair of doublestrand breaks
    • Lieber, M. R., U. Grawunder, X. Wu, and M. Yaneva. 1997. Tying loose ends: roles of Ku and DNA-dependent protein kinase in the repair of doublestrand breaks. Curr. Opin. Genet. Dev. 7:99-104.
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 99-104
    • Lieber, M.R.1    Grawunder, U.2    Wu, X.3    Yaneva, M.4
  • 29
    • 0022827675 scopus 로고
    • Mechanism of interaction between Ku protein and DNA
    • Mimori, T., and J. A. Hardin. 1986. Mechanism of interaction between Ku protein and DNA. J. Biol. Chem. 261:10375-10379.
    • (1986) J. Biol. Chem. , vol.261 , pp. 10375-10379
    • Mimori, T.1    Hardin, J.A.2
  • 30
    • 0028016304 scopus 로고
    • Phosphorylation of the p34 subunit of human single-stranded-DNA-binding protein in cyclin A-activated G1 extracts is catalyzed by cdk-cyclin A complex and DNAdependent protein kinase
    • Pan, Z., A. A. Amin, E. Gibbs, H. Niu, and J. Hurwitz. 1994. Phosphorylation of the p34 subunit of human single-stranded-DNA-binding protein in cyclin A-activated G1 extracts is catalyzed by cdk-cyclin A complex and DNAdependent protein kinase. Proc. Natl. Acad. Sci. USA 91:8343-8347.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8343-8347
    • Pan, Z.1    Amin, A.A.2    Gibbs, E.3    Niu, H.4    Hurwitz, J.5
  • 31
    • 0030907318 scopus 로고    scopus 로고
    • Ku proteins join DNA fragments as shown by atomic force microscopy
    • Pang, D., S. Yoo, W. S. Dynan, M. Jung, and A. Dritschilo. 1997. Ku proteins join DNA fragments as shown by atomic force microscopy. Cancer Res. 57:1412-1415.
    • (1997) Cancer Res. , vol.57 , pp. 1412-1415
    • Pang, D.1    Yoo, S.2    Dynan, W.S.3    Jung, M.4    Dritschilo, A.5
  • 32
    • 0027245559 scopus 로고
    • V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair
    • Pergola, F., M. Z. Zdzienicka, and M. Lieber. 1993. V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair. Mol. Cell. Biol. 13:3464-3471.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3464-3471
    • Pergola, F.1    Zdzienicka, M.Z.2    Lieber, M.3
  • 33
    • 0028902932 scopus 로고
    • Loss of the catalytic subunit of DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells
    • Peterson, S. R., A. Kurimasa, M. Oshimura, W. S. Dynan, E. M. Bradbury, and D. J. Chen. 1995. Loss of the catalytic subunit of DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells. Proc. Natl. Acad. Sci. USA 92:3171-3174.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3171-3174
    • Peterson, S.R.1    Kurimasa, A.2    Oshimura, M.3    Dynan, W.S.4    Bradbury, E.M.5    Chen, D.J.6
  • 34
    • 0030749258 scopus 로고    scopus 로고
    • A newly identified DNA ligase of S. cerevisiae involved in RAD52-independent repair of DNA double-strand breaks
    • Schar, P., G. Herrmann, G. Daly, and T. Lindahl. 1997. A newly identified DNA ligase of S. cerevisiae involved in RAD52-independent repair of DNA double-strand breaks. Genes Dev. 11:1912-1924.
    • (1997) Genes Dev. , vol.11 , pp. 1912-1924
    • Schar, P.1    Herrmann, G.2    Daly, G.3    Lindahl, T.4
  • 35
    • 0028112944 scopus 로고
    • Restoration of X-ray resistance and V(D)J recombination in mutant mammalian cells by Ku
    • Smider, V., W. K. Rathmell, M. Lieber, and G. Chu. 1994. Restoration of X-ray resistance and V(D)J recombination in mutant mammalian cells by Ku. Science 266:288-291.
    • (1994) Science , vol.266 , pp. 288-291
    • Smider, V.1    Rathmell, W.K.2    Lieber, M.3    Chu, G.4
  • 37
    • 0027156278 scopus 로고
    • Impairment of V(D)J recombination in double-strand break repair mutants
    • Taccioli, G. E., G. Rathbun, E. Oltz, T. Stamato, P. A. Jeggo, and F. W. Alt. 1993. Impairment of V(D)J recombination in double-strand break repair mutants. Science 260:207-210.
    • (1993) Science , vol.260 , pp. 207-210
    • Taccioli, G.E.1    Rathbun, G.2    Oltz, E.3    Stamato, T.4    Jeggo, P.A.5    Alt, F.W.6
  • 39
    • 0030849085 scopus 로고    scopus 로고
    • Identification of S. cerevisiae DNA ligase IV: Involvement in DNA double-strand break repair
    • Teo, S. H., and S. P. Jackson. 1997. Identification of S. cerevisiae DNA ligase IV: involvement in DNA double-strand break repair. EMBO J. 16:4788-4795.
    • (1997) EMBO J. , vol.16 , pp. 4788-4795
    • Teo, S.H.1    Jackson, S.P.2
  • 41
    • 0030811523 scopus 로고    scopus 로고
    • Yeast DNA ligase IV mediates non-homologous DNA end joining
    • Wilson, T. E., U. Grawunder, and M. R. Lieber. 1997. Yeast DNA ligase IV mediates non-homologous DNA end joining. Nature 388:495-498.
    • (1997) Nature , vol.388 , pp. 495-498
    • Wilson, T.E.1    Grawunder, U.2    Lieber, M.R.3
  • 42
    • 0030746109 scopus 로고    scopus 로고
    • Interaction of DNA-dependent protein kinase with DNA and with Ku: Biochemical and atomic-force microscopy
    • Yaneva, M., T. Kowaleski, and M. R. Lieber. 1997. Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy. EMBO J. 16:5098-5112.
    • (1997) EMBO J. , vol.16 , pp. 5098-5112
    • Yaneva, M.1    Kowaleski, T.2    Lieber, M.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.