-
1
-
-
57149111046
-
Physiological basis for the use of erythropoietin in critically ill patients at risk for acute kidney injury
-
10.1097/MCC.0b013e328317ee82, 19005302
-
Bernhardt WM, Eckardt KU. Physiological basis for the use of erythropoietin in critically ill patients at risk for acute kidney injury. Curr Opin Crit Care 2008, 14:621-626. 10.1097/MCC.0b013e328317ee82, 19005302.
-
(2008)
Curr Opin Crit Care
, vol.14
, pp. 621-626
-
-
Bernhardt, W.M.1
Eckardt, K.U.2
-
2
-
-
0036710591
-
Signal transduction to hypoxia-inducible factor 1
-
10.1016/S0006-2952(02)01168-1, 12213597
-
Semenza G. Signal transduction to hypoxia-inducible factor 1. Biochem Pharmacol 2002, 64:993-998. 10.1016/S0006-2952(02)01168-1, 12213597.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 993-998
-
-
Semenza, G.1
-
3
-
-
69849113833
-
HIF in kidney disease and development
-
10.1681/ASN.2008070804, 19118148
-
Gunaratnam L, Bonventre JV. HIF in kidney disease and development. J Am Soc Nephrol 2009, 20:1877-1887. 10.1681/ASN.2008070804, 19118148.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1877-1887
-
-
Gunaratnam, L.1
Bonventre, J.V.2
-
4
-
-
33644976897
-
Current understanding of HIF in renal disease
-
10.1159/000090187, 16534228
-
Rosenberger C, Rosen S, Heyman S. Current understanding of HIF in renal disease. Kidney Blood Press Res 2005, 28:325-340. 10.1159/000090187, 16534228.
-
(2005)
Kidney Blood Press Res
, vol.28
, pp. 325-340
-
-
Rosenberger, C.1
Rosen, S.2
Heyman, S.3
-
5
-
-
33745665335
-
HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation
-
10.1016/j.yjmcc.2006.04.009, 16765982
-
Willam C, Maxwell PH, Nichols L, et al. HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation. J Mol Cell Cardiol 2006, 41:68-77. 10.1016/j.yjmcc.2006.04.009, 16765982.
-
(2006)
J Mol Cell Cardiol
, vol.41
, pp. 68-77
-
-
Willam, C.1
Maxwell, P.H.2
Nichols, L.3
-
6
-
-
33846220305
-
Expression and actions of HIF prolyl-4-hydroxylase in the rat kidneys
-
10.1152/ajprenal.00457.2005, 16885149
-
Li N, Yi F, Sundy CM, et al. Expression and actions of HIF prolyl-4-hydroxylase in the rat kidneys. Am J Physiol Renal Physiol 2007, 292:F207-F216. 10.1152/ajprenal.00457.2005, 16885149.
-
(2007)
Am J Physiol Renal Physiol
, vol.292
-
-
Li, N.1
Yi, F.2
Sundy, C.M.3
-
7
-
-
65649105473
-
HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury
-
10.2353/ajpath.2009.080687, 2671255, 19349364
-
Schodel J, Klanke B, Weidemann A, et al. HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury. Am J Pathol 2009, 174:1663-1674. 10.2353/ajpath.2009.080687, 2671255, 19349364.
-
(2009)
Am J Pathol
, vol.174
, pp. 1663-1674
-
-
Schodel, J.1
Klanke, B.2
Weidemann, A.3
-
8
-
-
54849418794
-
Acute inactivation of the VHL gene contributes to protective effects of ischemic preconditioning in the mouse kidney
-
10.1159/000166994, 2657226, 18957870
-
Iguchi M, Kakinuma Y, Kurabayashi A, et al. Acute inactivation of the VHL gene contributes to protective effects of ischemic preconditioning in the mouse kidney. Nephron Exp Nephrol 2008, 110:e82-e90. 10.1159/000166994, 2657226, 18957870.
-
(2008)
Nephron Exp Nephrol
, vol.110
-
-
Iguchi, M.1
Kakinuma, Y.2
Kurabayashi, A.3
-
9
-
-
33644837102
-
HIF-1 activation by prolyl 4-hyroxylase-2 gene silencing attenuates myocardial ischemia-reperfusion injury
-
10.1161/01.RES.0000197816.63513.27, 16306444
-
Natarajan R, Salloum FN, Fisher BJ, Kukreja RC, Fowler AA. HIF-1 activation by prolyl 4-hyroxylase-2 gene silencing attenuates myocardial ischemia-reperfusion injury. Circ Res 2006, 98:133-140. 10.1161/01.RES.0000197816.63513.27, 16306444.
-
(2006)
Circ Res
, vol.98
, pp. 133-140
-
-
Natarajan, R.1
Salloum, F.N.2
Fisher, B.J.3
Kukreja, R.C.4
Fowler, A.A.5
-
10
-
-
33947727879
-
Use of a constitutively active hypoxia-inducible factor-1alpha transgene as a therapeutic strategy in no-option critical limb ischemia patients: phase I dose-escalation experience
-
Rajagopalan S, Olin J, Deitcher S, et al. Use of a constitutively active hypoxia-inducible factor-1alpha transgene as a therapeutic strategy in no-option critical limb ischemia patients: phase I dose-escalation experience. Circulation 2007, 115:1234-1243.
-
(2007)
Circulation
, vol.115
, pp. 1234-1243
-
-
Rajagopalan, S.1
Olin, J.2
Deitcher, S.3
-
11
-
-
70649085074
-
HIF prolyl 4-hydroxylases and their potential as drug targets
-
10.2174/138161209789649457, 19671043
-
Myllyharju J. HIF prolyl 4-hydroxylases and their potential as drug targets. Curr Pharm Des 2009, 15:3878-3885. 10.2174/138161209789649457, 19671043.
-
(2009)
Curr Pharm Des
, vol.15
, pp. 3878-3885
-
-
Myllyharju, J.1
-
12
-
-
61849083011
-
Novel therapeutic approach targeting the HIF-HRE system in the kidney
-
full_text, 19227454
-
Nangaku M. Novel therapeutic approach targeting the HIF-HRE system in the kidney. Adv Exp Med Biol 2009, 645:81-86. full_text, 19227454.
-
(2009)
Adv Exp Med Biol
, vol.645
, pp. 81-86
-
-
Nangaku, M.1
-
13
-
-
70449527373
-
Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing
-
10.1007/s00018-009-0147-7, 19756382
-
Webb JD, Coleman ML, Pugh CW. Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing. Cell Mol Life Sci 2009, 66:3539-3554. 10.1007/s00018-009-0147-7, 19756382.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 3539-3554
-
-
Webb, J.D.1
Coleman, M.L.2
Pugh, C.W.3
-
14
-
-
70350692093
-
The human HIF (hypoxia-inducible factor)-3alpha gene is a HIF-1 target gene and may modulate hypoxic gene induction
-
10.1042/BJ20090120, 19694616
-
Tanaka T, Wiesener M, Bernhardt W, Eckardt KU, Warnecke C. The human HIF (hypoxia-inducible factor)-3alpha gene is a HIF-1 target gene and may modulate hypoxic gene induction. Biochem J 2009, 424:143-151. 10.1042/BJ20090120, 19694616.
-
(2009)
Biochem J
, vol.424
, pp. 143-151
-
-
Tanaka, T.1
Wiesener, M.2
Bernhardt, W.3
Eckardt, K.U.4
Warnecke, C.5
-
15
-
-
33644620740
-
NO restores HIF-1 alpha hydroxylation during hypoxia: role of reactive oxygen species
-
10.1016/j.freeradbiomed.2005.05.009, 16140212
-
Callapina M, Zhou J, Schmid T, Kohl R, Brune B. NO restores HIF-1 alpha hydroxylation during hypoxia: role of reactive oxygen species. Free Radic Biol Med 2005, 39:925-936. 10.1016/j.freeradbiomed.2005.05.009, 16140212.
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 925-936
-
-
Callapina, M.1
Zhou, J.2
Schmid, T.3
Kohl, R.4
Brune, B.5
-
16
-
-
33646127170
-
The VHL/HIF oxygen-sensing pathway and its relevance to kidney disease
-
Haase VH. The VHL/HIF oxygen-sensing pathway and its relevance to kidney disease. Kidney Int 2006, 69:1302-1307.
-
(2006)
Kidney Int
, vol.69
, pp. 1302-1307
-
-
Haase, V.H.1
-
17
-
-
33947520506
-
Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF
-
10.1074/jbc.M610415200, 17182618
-
Koivunen P, Hirsila M, Remes AM, Hassinen IE, Kivirikko KI, Myllyharju J. Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF. J Biol Chem 2007, 282:4524-4532. 10.1074/jbc.M610415200, 17182618.
-
(2007)
J Biol Chem
, vol.282
, pp. 4524-4532
-
-
Koivunen, P.1
Hirsila, M.2
Remes, A.M.3
Hassinen, I.E.4
Kivirikko, K.I.5
Myllyharju, J.6
-
18
-
-
77953319433
-
Extended ischemia prevents HIF1 alpha degradation at reoxygenation by impairing prolylhydroxylation: role of Krebs cycle metabolites
-
10.1074/jbc.M110.101048, 20368331
-
Serra-Perez A, Planas AM, Nunez-O'Mara A, et al. Extended ischemia prevents HIF1 alpha degradation at reoxygenation by impairing prolylhydroxylation: role of Krebs cycle metabolites. J Biol Chem 2010, 285:18217-1824. 10.1074/jbc.M110.101048, 20368331.
-
(2010)
J Biol Chem
, vol.285
, pp. 18217-21824
-
-
Serra-Perez, A.1
Planas, A.M.2
Nunez-O'Mara, A.3
-
19
-
-
33748913696
-
Renal Parenchymal Oxygenation and Hypoxia Adaptation in Acute Kidney Injury
-
10.1111/j.1440-1681.2006.04472.x, 17002677
-
Rosenberger C, Rosen S, Heyman SN. Renal Parenchymal Oxygenation and Hypoxia Adaptation in Acute Kidney Injury. Clin Exp Pharmacol Physiol 2006, 33:980-988. 10.1111/j.1440-1681.2006.04472.x, 17002677.
-
(2006)
Clin Exp Pharmacol Physiol
, vol.33
, pp. 980-988
-
-
Rosenberger, C.1
Rosen, S.2
Heyman, S.N.3
-
20
-
-
47149092668
-
Renal parenchymal hypoxia, hypoxia response and the progression of chronic kidney disease
-
10.1159/000146075, 18635927
-
Heyman SN, Khamaisi M, Rosen S, Rosenberger C. Renal parenchymal hypoxia, hypoxia response and the progression of chronic kidney disease. Am J Nephrol 2008, 28:998-1006. 10.1159/000146075, 18635927.
-
(2008)
Am J Nephrol
, vol.28
, pp. 998-1006
-
-
Heyman, S.N.1
Khamaisi, M.2
Rosen, S.3
Rosenberger, C.4
-
21
-
-
18444380862
-
Expression of hypoxiainducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys
-
10.1097/01.ASN.0000017223.49823.2A, 12089367
-
Rosenberger C, Mandriota S, Jurgensen JS, et al. Expression of hypoxiainducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys. J Am Soc Nephrol 2002, 13:1721-1732. 10.1097/01.ASN.0000017223.49823.2A, 12089367.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1721-1732
-
-
Rosenberger, C.1
Mandriota, S.2
Jurgensen, J.S.3
-
22
-
-
33745683632
-
Hypoxia inducible factors and tubular cell survival in isolated perfused kidneys
-
10.1038/sj.ki.5000395, 16710354
-
Rosenberger C, Shina A, Rosen S, Goldfarb M, Eckardt K, Heyman SN. Hypoxia inducible factors and tubular cell survival in isolated perfused kidneys. Kidney Int 2006, 70:60-70. 10.1038/sj.ki.5000395, 16710354.
-
(2006)
Kidney Int
, vol.70
, pp. 60-70
-
-
Rosenberger, C.1
Shina, A.2
Rosen, S.3
Goldfarb, M.4
Eckardt, K.5
Heyman, S.N.6
-
23
-
-
19944432424
-
Upregulation of HIF in acute renal failure - evidence for a protective transcriptional response to hypoxia
-
10.1111/j.1523-1755.2005.67110.x, 15673301
-
Rosenberger C, Heyman SN, Rosen S, et al. Upregulation of HIF in acute renal failure - evidence for a protective transcriptional response to hypoxia. Kidney Int 2005, 67:531-542. 10.1111/j.1523-1755.2005.67110.x, 15673301.
-
(2005)
Kidney Int
, vol.67
, pp. 531-542
-
-
Rosenberger, C.1
Heyman, S.N.2
Rosen, S.3
-
24
-
-
75749150800
-
Hypoxia-inducible factor-2α-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization
-
10.1038/ki.2009.460, 20016470
-
Paliege A, Rosenberger C, Bondke A, et al. Hypoxia-inducible factor-2α-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization. Kidney Int 2010, 77:312-318. 10.1038/ki.2009.460, 20016470.
-
(2010)
Kidney Int
, vol.77
, pp. 312-318
-
-
Paliege, A.1
Rosenberger, C.2
Bondke, A.3
-
25
-
-
0042932770
-
Cellular responses to hypoxia after renal segmental infarction
-
10.1046/j.1523-1755.2003.00159.x, 12911537
-
Rosenberger C, Griethe W, Gruber G, et al. Cellular responses to hypoxia after renal segmental infarction. Kidney Int 2003, 64:874-886. 10.1046/j.1523-1755.2003.00159.x, 12911537.
-
(2003)
Kidney Int
, vol.64
, pp. 874-886
-
-
Rosenberger, C.1
Griethe, W.2
Gruber, G.3
-
26
-
-
42949166878
-
Evidence for sustained renal hypoxia and transient hypoxia adaptation in experimental rhabdomyolysis-induced acute kidney injury
-
Rosenberger C, Goldfarb M, Shina A, et al. Evidence for sustained renal hypoxia and transient hypoxia adaptation in experimental rhabdomyolysis-induced acute kidney injury. Nephrol Dial Transpl 2008, 23:1135-1143.
-
(2008)
Nephrol Dial Transpl
, vol.23
, pp. 1135-1143
-
-
Rosenberger, C.1
Goldfarb, M.2
Shina, A.3
-
27
-
-
48049099965
-
Liver HIF-1 alpha induction precedes apoptosis following normothermic ischemia-reperfusion in rats
-
10.1016/j.transproceed.2008.05.037, 18675125
-
Cursio R, Miele C, Filippa N, Van Obberghen E, Gugenheim J. Liver HIF-1 alpha induction precedes apoptosis following normothermic ischemia-reperfusion in rats. Transplant Proc 2008, 40:2042-2045. 10.1016/j.transproceed.2008.05.037, 18675125.
-
(2008)
Transplant Proc
, vol.40
, pp. 2042-2045
-
-
Cursio, R.1
Miele, C.2
Filippa, N.3
Van Obberghen, E.4
Gugenheim, J.5
-
28
-
-
72949089927
-
Experimental ischemia-reperfusion - biases and myths: the proximal vs. distal hypoxic tubular injury debate revisited
-
10.1038/ki.2009.347, 19759527
-
Heyman SN, Rosenberger C, Rosen S. Experimental ischemia-reperfusion - biases and myths: the proximal vs. distal hypoxic tubular injury debate revisited. Kidney Int 2010, 77:9-16. 10.1038/ki.2009.347, 19759527.
-
(2010)
Kidney Int
, vol.77
, pp. 9-16
-
-
Heyman, S.N.1
Rosenberger, C.2
Rosen, S.3
-
29
-
-
33645673448
-
Acute-on-chronic renal failure in the rat: Functional compensation and hypoxia tolerance
-
10.1159/000091783, 16508244
-
Goldfarb M, Rosenberger C, Abassi Z, et al. Acute-on-chronic renal failure in the rat: Functional compensation and hypoxia tolerance. Am J Nephrol 2006, 26:22-33. 10.1159/000091783, 16508244.
-
(2006)
Am J Nephrol
, vol.26
, pp. 22-33
-
-
Goldfarb, M.1
Rosenberger, C.2
Abassi, Z.3
-
30
-
-
37249086816
-
Adaptation to hypoxia in the diabetic rat kidney
-
10.1038/sj.ki.5002567, 17914354
-
Rosenberger C, Khamaisi M, Abassi Z, et al. Adaptation to hypoxia in the diabetic rat kidney. Kidney Int 2008, 73:34-42. 10.1038/sj.ki.5002567, 17914354.
-
(2008)
Kidney Int
, vol.73
, pp. 34-42
-
-
Rosenberger, C.1
Khamaisi, M.2
Abassi, Z.3
-
31
-
-
33846012220
-
Immunohistochemical Detection of Hypoxia-Inducible Factor-1alpha in Human Renal Allograft Biopsies
-
10.1681/ASN.2006070792, 17182883
-
Rosenberger C, Pratschke J, Rudolph B, et al. Immunohistochemical Detection of Hypoxia-Inducible Factor-1alpha in Human Renal Allograft Biopsies. J Am Soc Nephrol 2007, 18:343-351. 10.1681/ASN.2006070792, 17182883.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 343-351
-
-
Rosenberger, C.1
Pratschke, J.2
Rudolph, B.3
-
32
-
-
38149075003
-
Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury
-
10.1681/ASN.2006090998, 2391027, 18178798
-
Hill P, Shukla D, Tran MG, et al. Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury. J Am Soc Nephrol 2008, 19:39-46. 10.1681/ASN.2006090998, 2391027, 18178798.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 39-46
-
-
Hill, P.1
Shukla, D.2
Tran, M.G.3
-
33
-
-
33745907573
-
Hypoxic preconditioning produces differential expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and its regulatory enzyme HIF prolyl hydroxylase 2 in neonatal rat brain
-
10.1016/j.neulet.2006.05.049, 16828226
-
Jones NM, Lee EM, Brown TG, Jarrott B, Beart PM. Hypoxic preconditioning produces differential expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and its regulatory enzyme HIF prolyl hydroxylase 2 in neonatal rat brain. Neurosci Lett 2006, 404:72-77. 10.1016/j.neulet.2006.05.049, 16828226.
-
(2006)
Neurosci Lett
, vol.404
, pp. 72-77
-
-
Jones, N.M.1
Lee, E.M.2
Brown, T.G.3
Jarrott, B.4
Beart, P.M.5
-
34
-
-
38349138807
-
Transgenic system for conditional induction and rescue of chronic myocardial hibernation provides insights into genomic programs of hibernation
-
10.1073/pnas.0707778105, 2224202, 18162550
-
May D, Gilon D, Djonov V, et al. Transgenic system for conditional induction and rescue of chronic myocardial hibernation provides insights into genomic programs of hibernation. Proc Natl Acad Sci USA 2008, 105:282-287. 10.1073/pnas.0707778105, 2224202, 18162550.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 282-287
-
-
May, D.1
Gilon, D.2
Djonov, V.3
-
35
-
-
0038037735
-
Regulation of angiogenesis by hypoxia: role of the HIF system
-
10.1038/nm0603-677, 12778166
-
Pugh CW, Ratcliffe PJ. Regulation of angiogenesis by hypoxia: role of the HIF system. Nat Med 2003, 9:677-684. 10.1038/nm0603-677, 12778166.
-
(2003)
Nat Med
, vol.9
, pp. 677-684
-
-
Pugh, C.W.1
Ratcliffe, P.J.2
-
36
-
-
73349131437
-
Repetitive hypoxic preconditioning attenuates renal ischemia/reperfusion induced oxidative injury via upregulating HIF-1 alpha-dependent bcl-2 signaling
-
10.1097/TP.0b013e3181bb4a07, 19996924
-
Yang CC, Lin LC, Wu MS, Chien CT, Lai MK. Repetitive hypoxic preconditioning attenuates renal ischemia/reperfusion induced oxidative injury via upregulating HIF-1 alpha-dependent bcl-2 signaling. Transplantation 2009, 88:1251-1260. 10.1097/TP.0b013e3181bb4a07, 19996924.
-
(2009)
Transplantation
, vol.88
, pp. 1251-1260
-
-
Yang, C.C.1
Lin, L.C.2
Wu, M.S.3
Chien, C.T.4
Lai, M.K.5
-
37
-
-
34548829081
-
HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques
-
10.1182/blood-2007-02-073254, 1976368, 17557894
-
Hsieh MM, Linde NS, Wynter A, et al. HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques. Blood 2007, 110:2140-2147. 10.1182/blood-2007-02-073254, 1976368, 17557894.
-
(2007)
Blood
, vol.110
, pp. 2140-2147
-
-
Hsieh, M.M.1
Linde, N.S.2
Wynter, A.3
-
38
-
-
54149114944
-
Activation of hypoxia inducible factors (HIF) ameliorates hypoxic distal tubular injury in the isolated perfused rat kidney
-
10.1093/ndt/gfn276, 18515655
-
Rosenberger C, Rosen S, Shina A, et al. Activation of hypoxia inducible factors (HIF) ameliorates hypoxic distal tubular injury in the isolated perfused rat kidney. Nephrol Dial transplant 2008, 23:3472-3478. 10.1093/ndt/gfn276, 18515655.
-
(2008)
Nephrol Dial transplant
, vol.23
, pp. 3472-3478
-
-
Rosenberger, C.1
Rosen, S.2
Shina, A.3
-
39
-
-
20144386806
-
A biologic role of HIF-1 in the renal medulla
-
10.1111/j.1523-1755.2005.00220.x, 15780095
-
Manotham K, Tanaka T, Ohse T, et al. A biologic role of HIF-1 in the renal medulla. Kidney Int 2005, 67:1428-1439. 10.1111/j.1523-1755.2005.00220.x, 15780095.
-
(2005)
Kidney Int
, vol.67
, pp. 1428-1439
-
-
Manotham, K.1
Tanaka, T.2
Ohse, T.3
-
40
-
-
33745820018
-
Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure
-
10.1681/ASN.2005121302, 16762988
-
Bernhardt WM, Campean V, Kany S, et al. Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure. J Am Soc Nephrol 2006, 17:1970-1978. 10.1681/ASN.2005121302, 16762988.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1970-1978
-
-
Bernhardt, W.M.1
Campean, V.2
Kany, S.3
-
41
-
-
75849163295
-
Donor treatment with a PHD inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model
-
10.1073/pnas.0903978106, 2795511, 19934037
-
Bernhardt WM, Gottmann U, Doyon F, et al. Donor treatment with a PHD inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model. Proc Natl Acad Sci USA 2009, 106:21276-21281. 10.1073/pnas.0903978106, 2795511, 19934037.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 21276-21281
-
-
Bernhardt, W.M.1
Gottmann, U.2
Doyon, F.3
-
42
-
-
40449110083
-
HIF activation protects from acute kidney injury
-
10.1681/ASN.2007040419, 2391048, 18256363
-
Weidemann A, Bernhardt WM, Klanke B, et al. HIF activation protects from acute kidney injury. J Am Soc Nephrol 2008, 19:486-494. 10.1681/ASN.2007040419, 2391048, 18256363.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 486-494
-
-
Weidemann, A.1
Bernhardt, W.M.2
Klanke, B.3
-
43
-
-
23744443462
-
HIF-1 activation attenuates postischemic myocardial injury: role for heme oxygenase-1 in modulating microvascular chemokine generation
-
10.1152/ajpheart.00089.2005, 15805230
-
Ockaili R, Natarajan R, Salloum F, et al. HIF-1 activation attenuates postischemic myocardial injury: role for heme oxygenase-1 in modulating microvascular chemokine generation. Am J Physiol Heart Circ Physiol 2005, 289:H542-H548. 10.1152/ajpheart.00089.2005, 15805230.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
Ockaili, R.1
Natarajan, R.2
Salloum, F.3
-
44
-
-
33744805400
-
Stabilization of hypoxia inducible factor rather than modulation of collagen metabolism improves cardiac function after acute myocardial infarction in rats
-
10.1016/j.ejheart.2005.10.009, 16513418
-
Philipp S, Jurgensen JS, Fielitz J, et al. Stabilization of hypoxia inducible factor rather than modulation of collagen metabolism improves cardiac function after acute myocardial infarction in rats. Eur J Heart Fail 2006, 8:347-354. 10.1016/j.ejheart.2005.10.009, 16513418.
-
(2006)
Eur J Heart Fail
, vol.8
, pp. 347-354
-
-
Philipp, S.1
Jurgensen, J.S.2
Fielitz, J.3
-
45
-
-
42149153182
-
Remote renal preconditioning-induced cardioprotection: a key role of hypoxia inducible factor-prolyl 4-hydroxylases
-
10.1007/s11010-008-9717-5, 18273560
-
Kant R, Diwan V, Jaggi AS, Singh N, Singh D. Remote renal preconditioning-induced cardioprotection: a key role of hypoxia inducible factor-prolyl 4-hydroxylases. Mol Cell Biochem 2008, 312:25-31. 10.1007/s11010-008-9717-5, 18273560.
-
(2008)
Mol Cell Biochem
, vol.312
, pp. 25-31
-
-
Kant, R.1
Diwan, V.2
Jaggi, A.S.3
Singh, N.4
Singh, D.5
-
46
-
-
52949111864
-
Activation of negative regulators of the hypoxia-inducible factor (HIF) pathway in human end-stage heart failure
-
10.1016/j.bbrc.2008.08.152, 18782560
-
Zolk O, Solbach TF, Eschenhagen T, Weidemann A, Fromm MF. Activation of negative regulators of the hypoxia-inducible factor (HIF) pathway in human end-stage heart failure. Biochem Biophys Res Commun 2008, 376:315-320. 10.1016/j.bbrc.2008.08.152, 18782560.
-
(2008)
Biochem Biophys Res Commun
, vol.376
, pp. 315-320
-
-
Zolk, O.1
Solbach, T.F.2
Eschenhagen, T.3
Weidemann, A.4
Fromm, M.F.5
-
47
-
-
77649127622
-
Heat acclimation-mediated cross-tolerance in cardioprotection: do HSP70 and HIF-1alpha play a role?
-
10.1111/j.1749-6632.2009.05101.x, 20201904
-
Horowitz M, Assadi H. Heat acclimation-mediated cross-tolerance in cardioprotection: do HSP70 and HIF-1alpha play a role?. Ann N Y Acad Sci 2010, 1188:199-206. 10.1111/j.1749-6632.2009.05101.x, 20201904.
-
(2010)
Ann N Y Acad Sci
, vol.1188
, pp. 199-206
-
-
Horowitz, M.1
Assadi, H.2
-
48
-
-
77955094939
-
Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1 alpha and induction of autophagy in SH-SY5Y cells
-
Wu Y, Li X, Xie W, Jankovic J, Le W, Pan T. Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1 alpha and induction of autophagy in SH-SY5Y cells. Neurochem Int 2010, 57:98-205.
-
(2010)
Neurochem Int
, vol.57
, pp. 98-205
-
-
Wu, Y.1
Li, X.2
Xie, W.3
Jankovic, J.4
Le, W.5
Pan, T.6
-
49
-
-
75149124682
-
Prolyl hydroxylase domain inhibitors: a route to HIF activation and neuroprotection
-
10.1089/ars.2009.2870, 19737089
-
Harten SK, Ashcroft M, Maxwell PH. Prolyl hydroxylase domain inhibitors: a route to HIF activation and neuroprotection. Antioxid Redox Signal 2010, 12:459-480. 10.1089/ars.2009.2870, 19737089.
-
(2010)
Antioxid Redox Signal
, vol.12
, pp. 459-480
-
-
Harten, S.K.1
Ashcroft, M.2
Maxwell, P.H.3
-
50
-
-
75149154666
-
HIF prolyl hydroxylase inhibitors prevent neuronal death induced by mitochondrial toxins: therapeutic implications for Huntington's disease and Alzheimer's disease
-
10.1089/ars.2009.2800, 2821149, 19659431
-
Niatsetskaya Z, Basso M, Speer RE, et al. HIF prolyl hydroxylase inhibitors prevent neuronal death induced by mitochondrial toxins: therapeutic implications for Huntington's disease and Alzheimer's disease. Antioxid Redox Signal 2010, 12:435-443. 10.1089/ars.2009.2800, 2821149, 19659431.
-
(2010)
Antioxid Redox Signal
, vol.12
, pp. 435-443
-
-
Niatsetskaya, Z.1
Basso, M.2
Speer, R.E.3
-
51
-
-
67650481882
-
Selective inhibition of hypoxiainducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways
-
10.1523/JNEUROSCI.1779-09.2009, 19587290
-
Siddiq A, Aminova LR, Troy CM, et al. Selective inhibition of hypoxiainducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways. J Neurosci 2009, 29:8828-8838. 10.1523/JNEUROSCI.1779-09.2009, 19587290.
-
(2009)
J Neurosci
, vol.29
, pp. 8828-8838
-
-
Siddiq, A.1
Aminova, L.R.2
Troy, C.M.3
-
52
-
-
34447568178
-
Hypoxia-inducible factors HIF-1alpha and HIF-2alpha are decreased in an experimental model of severe respiratory distress syndrome in preterm lambs
-
10.1152/ajplung.00372.2006, 17307811
-
Grover TR, Asikainen TM, Kinsella JP, Abman SH, White CW. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha are decreased in an experimental model of severe respiratory distress syndrome in preterm lambs. Am J Physiol Lung Cell Mol Physiol 2007, 292:L1345-L1351. 10.1152/ajplung.00372.2006, 17307811.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
-
-
Grover, T.R.1
Asikainen, T.M.2
Kinsella, J.P.3
Abman, S.H.4
White, C.W.5
-
53
-
-
68549112685
-
HIF-1alpha is necessary to support gluconeogenesis during liver regeneration
-
10.1016/j.bbrc.2009.07.115, 19643083
-
Tajima T, Goda N, Fujiki N, et al. HIF-1alpha is necessary to support gluconeogenesis during liver regeneration. Biochem Biophys Res Commun 2009, 387:789-794. 10.1016/j.bbrc.2009.07.115, 19643083.
-
(2009)
Biochem Biophys Res Commun
, vol.387
, pp. 789-794
-
-
Tajima, T.1
Goda, N.2
Fujiki, N.3
-
54
-
-
6444242574
-
Inhibition of endogenous HIF inactivation induces angiogenesis in ischaemic skeletal muscles of mice
-
10.1113/jphysiol.2004.069757, 1665195, 15319416
-
Milkiewicz M, Pugh CW, Egginton S. Inhibition of endogenous HIF inactivation induces angiogenesis in ischaemic skeletal muscles of mice. J Physiol 2004, 560:21-26. 10.1113/jphysiol.2004.069757, 1665195, 15319416.
-
(2004)
J Physiol
, vol.560
, pp. 21-26
-
-
Milkiewicz, M.1
Pugh, C.W.2
Egginton, S.3
-
55
-
-
73949085704
-
Synergistic effect of HIF-1alpha gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
-
10.1073/pnas.0911921106, 2787122, 19948968
-
Rey S, Lee K, Wang CJ, et al. Synergistic effect of HIF-1alpha gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia. Proc Natl Acad Sci USA 2009, 106:20399-20404. 10.1073/pnas.0911921106, 2787122, 19948968.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 20399-20404
-
-
Rey, S.1
Lee, K.2
Wang, C.J.3
-
56
-
-
33645097572
-
Induction of the nuclear factor HIF-1alpha in acetaminophen toxicity: evidence for oxidative stress
-
10.1016/j.bbrc.2006.02.143, 16530163
-
James LP, Donahower B, Burke AS, McCullough S, Hinson JA. Induction of the nuclear factor HIF-1alpha in acetaminophen toxicity: evidence for oxidative stress. Biochem Biophys Res Commun 2006, 343:171-176. 10.1016/j.bbrc.2006.02.143, 16530163.
-
(2006)
Biochem Biophys Res Commun
, vol.343
, pp. 171-176
-
-
James, L.P.1
Donahower, B.2
Burke, A.S.3
McCullough, S.4
Hinson, J.A.5
-
57
-
-
27744574735
-
The effect of age and calorie restriction on HIF-1-responsive genes in aged liver
-
10.1007/s10522-004-7381-z, 15834661
-
Kang MJ, Kim HJ, Kim HK, et al. The effect of age and calorie restriction on HIF-1-responsive genes in aged liver. Biogerontology 2005, 6:27-37. 10.1007/s10522-004-7381-z, 15834661.
-
(2005)
Biogerontology
, vol.6
, pp. 27-37
-
-
Kang, M.J.1
Kim, H.J.2
Kim, H.K.3
-
58
-
-
77954367656
-
Involvement of net and HIF-1alpha in distinct yet intricately linked hypoxia-induced signaling pathways
-
10.1074/jbc.M110.121723, 20427288
-
Serchov T, Dubois-Pot-Schneider H, Charlot C, Rosl F, Wasylyk B. Involvement of net and HIF-1alpha in distinct yet intricately linked hypoxia-induced signaling pathways. J Biol Chem 2010, 285:21223-21232. 10.1074/jbc.M110.121723, 20427288.
-
(2010)
J Biol Chem
, vol.285
, pp. 21223-21232
-
-
Serchov, T.1
Dubois-Pot-Schneider, H.2
Charlot, C.3
Rosl, F.4
Wasylyk, B.5
-
59
-
-
79953003705
-
Renal hypoxia inducible factors (HIF) and STAT3 cross-talk in vivo [abstract]
-
Nechemia-Arbely Y, Rosenberger C, Khamaisi M, Koesters R, Shina A, Klaus S, Shriki A, Rosen S, Axelrod JH, Heyman SN. Renal hypoxia inducible factors (HIF) and STAT3 cross-talk in vivo [abstract]. J Am Soc Nephrol 2009, 20:F-FC184.
-
(2009)
J Am Soc Nephrol
, vol.20
-
-
Nechemia-Arbely, Y.1
Rosenberger, C.2
Khamaisi, M.3
Koesters, R.4
Shina, A.5
Klaus, S.6
Shriki, A.7
Rosen, S.8
Axelrod, J.H.9
Heyman, S.N.10
-
60
-
-
77953954331
-
The role of HIF prolyl hydroxylases in tumour growth
-
10.1111/j.1582-4934.2010.01030.x, 20178464
-
Jokilehto T, Jaakkola PM. The role of HIF prolyl hydroxylases in tumour growth. J Cell Mol Med 2010, 14:758-770. 10.1111/j.1582-4934.2010.01030.x, 20178464.
-
(2010)
J Cell Mol Med
, vol.14
, pp. 758-770
-
-
Jokilehto, T.1
Jaakkola, P.M.2
-
61
-
-
36849021771
-
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition
-
2082142, 18037992
-
Higgins DF, Kimura K, Bernhardt WM, et al. Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. J Clin Invest 2007, 117:3810-3820. 2082142, 18037992.
-
(2007)
J Clin Invest
, vol.117
, pp. 3810-3820
-
-
Higgins, D.F.1
Kimura, K.2
Bernhardt, W.M.3
-
62
-
-
33749316052
-
Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1
-
10.1152/ajpregu.00794.2005, 16627691
-
Nevo O, Soleymanlou N, Wu Y, et al. Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1. Am J Physiol Regul Integr Comp Physiol 2006, 291:R1085-R1093. 10.1152/ajpregu.00794.2005, 16627691.
-
(2006)
Am J Physiol Regul Integr Comp Physiol
, vol.291
-
-
Nevo, O.1
Soleymanlou, N.2
Wu, Y.3
|