5,6,3′,4′-tetrahydroxy-7-methoxyflavone as a novel potential proteasome inhibitor

Planta Medica

Volumn 76, Issue 10, 2010, Pages 987-994

  Chang, Tsui Ling ^a   Ding, Hsiou Yu ^b   Teng, Kang Ning ^a   Fang, Yi Chen ^a  

^a NATIONAL UNIVERSITY OF TAINAN   (Taiwan)

^b CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

26S proteasome; 5,6,3 ,4 tetrahydroxy 7 methoxyflavone; 5,6,4 trihydroxy 7,3 dimethoxyflavone; Anisomeles ovata R. Br.; Labiatae; MG132; proteasome inhibitor

Indexed keywords

5,6,4' TRIHYDROXY 7,3' DIMETHOXYFLAVONE; ANISOMELES OVATA EXTRACT; ANTINEOPLASTIC AGENT; AROMATIC COMPOUND; CASPASE; CHYMOTRYPSIN; DITERPENOID; DNA 26S; FLAVONE DERIVATIVE; METHANOL; PEDALITIN; PLANT EXTRACT; PROTEASOME INHIBITOR; TRYPSIN; UNCLASSIFIED DRUG;

ANISOMELES OVATA; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMOTHERAPY; CONTROLLED STUDY; DRUG ISOLATION; DRUG MECHANISM; DRUG POTENTIATION; DRUG PURIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ERYTHROCYTE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; MEDICINAL PLANT; NONHUMAN; PROTEIN DEGRADATION; STRUCTURE ACTIVITY RELATION; SWINE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ENZYME INHIBITORS; ERYTHROCYTES; FLAVONES; INHIBITORY CONCENTRATION 50; LAMIACEAE; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; PROTEASOME ENDOPEPTIDASE COMPLEX; SWINE; TIME FACTORS;

ANISOMELES; LAMIACEAE; SUIDAE;

EID: 77954882151     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1240899     Document Type: Article

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