-
1
-
-
0033029551
-
St John's wort: A new alternative for depression?
-
Josey ES, Tackett RL (1999) St John's wort: a new alternative for depression? Int J Clin Pharmacol Ther 37(3): 111-119
-
(1999)
Int J Clin Pharmacol Ther
, vol.37
, Issue.3
, pp. 111-119
-
-
Josey, E.S.1
Tackett, R.L.2
-
2
-
-
4744344025
-
Undeclared exposure to St John's wort in hospitalized patients
-
Martin-Facklam M, Rieger K, Riedel KD, Burhenne J, Walter-Sack I, Haefeli WE (2004) Undeclared exposure to St John's wort in hospitalized patients. Br J Clin Pharmacol 58(4):437-441
-
(2004)
Br J Clin Pharmacol
, vol.58
, Issue.4
, pp. 437-441
-
-
Martin-Facklam, M.1
Rieger, K.2
Riedel, K.D.3
Burhenne, J.4
Walter-Sack, I.5
Haefeli, W.E.6
-
3
-
-
0034922290
-
Inhibition of substance P-induced cytokine synthesis by St John's wort extracts
-
Fiebich BL, Hoellig A, Lieb K (2001) Inhibition of substance P-induced cytokine synthesis by St John's wort extracts. Pharmacopsychiatry 34 [Suppl 1]:S26-S28
-
(2001)
Pharmacopsychiatry
, vol.34
, Issue.1 SUPPL.
-
-
Fiebich, B.L.1
Hoellig, A.2
Lieb, K.3
-
4
-
-
0033612827
-
Antibacterial activity of hyperforin from St John's wort
-
Fiebich BL, Heinrich M, Langosch JM, Kammerer N, Lieb K (1999) Antibacterial activity of hyperforin from St John's wort. Lancet 354(9180):777
-
(1999)
Lancet
, vol.354
, Issue.9180
, pp. 777
-
-
Fiebich, B.L.1
Heinrich, M.2
Langosch, J.M.3
Kammerer, N.4
Lieb, K.5
-
5
-
-
3843130941
-
Antioxidant activity of a flavonoidrich extract of Hypericum perforatum L. in vitro
-
Zou Y, Lu Y, Wei D (2004) Antioxidant activity of a flavonoidrich extract of Hypericum perforatum L. in vitro. J Agric Food Chem 52(16):5032-5039
-
(2004)
J Agric Food Chem
, vol.52
, Issue.16
, pp. 5032-5039
-
-
Zou, Y.1
Lu, Y.2
Wei, D.3
-
6
-
-
0036213362
-
Hypericin - A new antiviral and antitumor photosensitizer: Mechanism of action and interaction with biological macromolecules
-
Miskovsky P (2002) Hypericin - a new antiviral and antitumor photosensitizer: mechanism of action and interaction with biological macromolecules. Curr Drug Targets 3(1):55-84
-
(2002)
Curr Drug Targets
, vol.3
, Issue.1
, pp. 55-84
-
-
Miskovsky, P.1
-
7
-
-
0028124542
-
Hypericin: A potential antiglioma therapy
-
discussion pp. 709-710
-
Couldwell WT, Gopalakrishna R, Hinton DR, He S, Weiss MH, Law RE, Apuzzo ML (1994) Hypericin: a potential antiglioma therapy. Neurosurgery 35(4):705-709 (discussion pp. 709-710)
-
(1994)
Neurosurgery
, vol.35
, Issue.4
, pp. 705-709
-
-
Couldwell, W.T.1
Gopalakrishna, R.2
Hinton, D.R.3
He, S.4
Weiss, M.H.5
Law, R.E.6
Apuzzo, M.L.7
-
8
-
-
0024847267
-
Hypericin and pseudohypericin specifically inhibit protein kinase C: Possible relation to their antiretroviral activity
-
Takahashi I, Nakanishi S, Kobayashi E, Nakano H, Suzuki K, Tamaoki T (1989) Hypericin and pseudohypericin specifically inhibit protein kinase C: possible relation to their antiretroviral activity. Biochem Biophys Res Commun 165(3):1207-1212
-
(1989)
Biochem Biophys Res Commun
, vol.165
, Issue.3
, pp. 1207-1212
-
-
Takahashi, I.1
Nakanishi, S.2
Kobayashi, E.3
Nakano, H.4
Suzuki, K.5
Tamaoki, T.6
-
9
-
-
0032968509
-
Hypericin as a non-antioxidant inhibitor of NF-kappa B
-
Bork PM, Bacher S, Schmitz ML, Kaspers U, Heinrich M (1999) Hypericin as a non-antioxidant inhibitor of NF-kappa B. Planta Med 65(4):297-300
-
(1999)
Planta Med
, vol.65
, Issue.4
, pp. 297-300
-
-
Bork, P.M.1
Bacher, S.2
Schmitz, M.L.3
Kaspers, U.4
Heinrich, M.5
-
10
-
-
0032540701
-
Photodynamic therapy
-
Dougherty TJ, Gomer CJ, Henderson BW, Jori G, Kessel D, Korbelik M, Moan J, Peng Q (1998) Photodynamic therapy. J Natl Cancer Inst 90(12):889-905
-
(1998)
J Natl Cancer Inst
, vol.90
, Issue.12
, pp. 889-905
-
-
Dougherty, T.J.1
Gomer, C.J.2
Henderson, B.W.3
Jori, G.4
Kessel, D.5
Korbelik, M.6
Moan, J.7
Peng, Q.8
-
11
-
-
0033605591
-
The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin
-
Assefa Z, Vantieghem A, Declercq W, Vandenabeele P, Vandenheede JR, Merlevede W, de Witte P, Agostinis P (1999) The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin. J Biol Chem 274(13):8788-8796
-
(1999)
J Biol Chem
, vol.274
, Issue.13
, pp. 8788-8796
-
-
Assefa, Z.1
Vantieghem, A.2
Declercq, W.3
Vandenabeele, P.4
Vandenheede, J.R.5
Merlevede, W.6
De Witte, P.7
Agostinis, P.8
-
12
-
-
0034782973
-
Intracellular localization of hypericin in human glioblastoma and carcinoma cell lines
-
Uzdensky AB, Ma LW, Iani V, Hjortland GO, Steen HB, Moan J (2001) Intracellular localization of hypericin in human glioblastoma and carcinoma cell lines. Lasers Med Sci 16(4):276-283
-
(2001)
Lasers Med Sci
, vol.16
, Issue.4
, pp. 276-283
-
-
Uzdensky, A.B.1
Ma, L.W.2
Iani, V.3
Hjortland, G.O.4
Steen, H.B.5
Moan, J.6
-
13
-
-
0032573396
-
Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis. Involvement of cytochrome c and procaspase-3 activation in the mechanism of apoptosis
-
Vantieghem A, Assefa Z, Vandenabeele P, Declercq W, Courtois S, Vandenheede JR, Merlevede W, de Witte P, Agostinis P (1998) Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis. Involvement of cytochrome c and procaspase-3 activation in the mechanism of apoptosis. FEBS Lett 440(1-2):19-24
-
(1998)
FEBS Lett
, vol.440
, Issue.1-2
, pp. 19-24
-
-
Vantieghem, A.1
Assefa, Z.2
Vandenabeele, P.3
Declercq, W.4
Courtois, S.5
Vandenheede, J.R.6
Merlevede, W.7
De Witte, P.8
Agostinis, P.9
-
14
-
-
0032750207
-
Over-expression of Bcl-2 does not protect cells from hypericin photo-induced mitochondrial membrane depolarization, but delays subsequent events in the apoptotic pathway
-
Chaloupka R, Petit PX, Israel N, Sureau F (1999) Over-expression of Bcl-2 does not protect cells from hypericin photo-induced mitochondrial membrane depolarization, but delays subsequent events in the apoptotic pathway. FEBS Lett 462(3):295-301
-
(1999)
FEBS Lett
, vol.462
, Issue.3
, pp. 295-301
-
-
Chaloupka, R.1
Petit, P.X.2
Israel, N.3
Sureau, F.4
-
15
-
-
0037020254
-
Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis
-
Vantieghem A, Xu Y, Assefa Z, Piette J, Vandenheede JR, Merlevede W, De Witte PA, Agostinis P (2002) Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. J Biol Chem 277(40):37718-37731
-
(2002)
J Biol Chem
, vol.277
, Issue.40
, pp. 37718-37731
-
-
Vantieghem, A.1
Xu, Y.2
Assefa, Z.3
Piette, J.4
Vandenheede, J.R.5
Merlevede, W.6
De Witte, P.A.7
Agostinis, P.8
-
16
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity
-
Karin M, Ben-Neriah Y (2000) Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol 18:621-663
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
17
-
-
0036217821
-
Natural products as targeted modulators of the nuclear factor-kappaB pathway
-
Bremner P, Heinrich M (2002) Natural products as targeted modulators of the nuclear factor-kappaB pathway. J Pharm Pharmacol 54(4):453-472
-
(2002)
J Pharm Pharmacol
, vol.54
, Issue.4
, pp. 453-472
-
-
Bremner, P.1
Heinrich, M.2
-
18
-
-
0030016595
-
Structure and functions of the 20S and 26S proteasomes
-
Coux O, Tanaka K, Goldberg AL (1996) Structure and functions of the 20S and 26S proteasomes. Annu Rev Biochem 65:801-847
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 801-847
-
-
Coux, O.1
Tanaka, K.2
Goldberg, A.L.3
-
19
-
-
0027980321
-
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B
-
Palombella VJ, Rando OJ, Goldberg AL, Maniatis T (1994) The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B. Cell 78(5):773-785
-
(1994)
Cell
, vol.78
, Issue.5
, pp. 773-785
-
-
Palombella, V.J.1
Rando, O.J.2
Goldberg, A.L.3
Maniatis, T.4
-
20
-
-
0033152760
-
Proteasome inhibitors: A novel class of potent and effective antitumor agents
-
Adams J, Palombella VJ, Sausville EA, Johnson J, Destree A, Lazarus DD, Maas J, Pien CS, Prakash S, Elliott PJ (1999) Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res 59(11):2615-2622
-
(1999)
Cancer Res
, vol.59
, Issue.11
, pp. 2615-2622
-
-
Adams, J.1
Palombella, V.J.2
Sausville, E.A.3
Johnson, J.4
Destree, A.5
Lazarus, D.D.6
Maas, J.7
Pien, C.S.8
Prakash, S.9
Elliott, P.J.10
-
21
-
-
0033038942
-
Proteasome inhibitors induce mitochondria-independent apoptosis in human glioma cells
-
Kitagawa H, Tani E, Ikemoto H, Ozaki I, Nakano A, Omura S (1999) Proteasome inhibitors induce mitochondria-independent apoptosis in human glioma cells. FEBS Lett 443(2):181-186
-
(1999)
FEBS Lett
, vol.443
, Issue.2
, pp. 181-186
-
-
Kitagawa, H.1
Tani, E.2
Ikemoto, H.3
Ozaki, I.4
Nakano, A.5
Omura, S.6
-
22
-
-
0033563113
-
Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells
-
Zhang XM, Lin H, Chen C, Chen BD (1999) Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells. Biochem J 340(Pt 1):127-133
-
(1999)
Biochem J
, vol.340
, Issue.1 PART
, pp. 127-133
-
-
Zhang, X.M.1
Lin, H.2
Chen, C.3
Chen, B.D.4
-
23
-
-
0039730001
-
How an inhibitor of the HIV-I protease modulates proteasome activity
-
Schmidtke G, Holzhutter HG, Bogyo M, Kairies N, Groll M, de Giuli R, Emch S, Groettrup M (1999) How an inhibitor of the HIV-I protease modulates proteasome activity. J Biol Chem 274(50):35734-35740
-
(1999)
J Biol Chem
, vol.274
, Issue.50
, pp. 35734-35740
-
-
Schmidtke, G.1
Holzhutter, H.G.2
Bogyo, M.3
Kairies, N.4
Groll, M.5
De Giuli, R.6
Emch, S.7
Groettrup, M.8
-
24
-
-
0037105651
-
The human immunodeficiency virus (HIV)-I protease inhibitor saquinavir inhibits proteasome function and causes apoptosis and radiosensitization in non-HIV-associated human cancer cells
-
Pajonk F, Himmelsbach J, Riess K, Sommer A, McBride WH (2002) The human immunodeficiency virus (HIV)-I protease inhibitor saquinavir inhibits proteasome function and causes apoptosis and radiosensitization in non-HIV-associated human cancer cells. Cancer Res 62(18):5230-5235
-
(2002)
Cancer Res
, vol.62
, Issue.18
, pp. 5230-5235
-
-
Pajonk, F.1
Himmelsbach, J.2
Riess, K.3
Sommer, A.4
McBride, W.H.5
-
25
-
-
0034237661
-
Apoptosis and radiosensitization of Hodgkin's cells by proteasome inhibition
-
Pajonk F, Pajonk K, McBride W (2000) Apoptosis and radiosensitization of Hodgkin's cells by proteasome inhibition. Int J Radiat Oncol Biol Phys 47(4):1025-1032
-
(2000)
Int J Radiat Oncol Biol Phys
, vol.47
, Issue.4
, pp. 1025-1032
-
-
Pajonk, F.1
Pajonk, K.2
McBride, W.3
-
26
-
-
0032499199
-
A proteolytic system that compensates for loss of proteasome function
-
Glas R, Bogyo M, McMaster JS, Gaczynska M, Ploegh HL (1998) A proteolytic system that compensates for loss of proteasome function. Nature 392(6676):618-622
-
(1998)
Nature
, vol.392
, Issue.6676
, pp. 618-622
-
-
Glas, R.1
Bogyo, M.2
McMaster, J.S.3
Gaczynska, M.4
Ploegh, H.L.5
-
27
-
-
0032607858
-
Alteration of caspase-3 (CPP32/Yama/apopain) in wild-type MCF-7, breast cancer cells
-
Kurokawa H, Nishio K, Fukumoto H, Tomonari A, Suzuki T, Saijo N (1999) Alteration of caspase-3 (CPP32/Yama/apopain) in wild-type MCF-7, breast cancer cells. Oncol Rep 6(1):33-37
-
(1999)
Oncol Rep
, vol.6
, Issue.1
, pp. 33-37
-
-
Kurokawa, H.1
Nishio, K.2
Fukumoto, H.3
Tomonari, A.4
Suzuki, T.5
Saijo, N.6
-
28
-
-
0035937426
-
Hypericin photo-induced apoptosis involves the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and activation of caspase-8
-
Schempp CM, Simon-Haarhaus B, Termeer CC, Simon JC (2001) Hypericin photo-induced apoptosis involves the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and activation of caspase-8. FEBS Lett 493(1):26-30
-
(2001)
FEBS Lett
, vol.493
, Issue.1
, pp. 26-30
-
-
Schempp, C.M.1
Simon-Haarhaus, B.2
Termeer, C.C.3
Simon, J.C.4
-
29
-
-
0034955273
-
Inhibition of interleukin12 production in lipopolysaccharide-activated mouse macrophages by hypericin, an active component of Hypericum perforatum
-
Kang BY, Chung SW, Kim TS (2001) Inhibition of interleukin12 production in lipopolysaccharide-activated mouse macrophages by hypericin, an active component of Hypericum perforatum. Planta Med 67(4):364-366
-
(2001)
Planta Med
, vol.67
, Issue.4
, pp. 364-366
-
-
Kang, B.Y.1
Chung, S.W.2
Kim, T.S.3
-
30
-
-
0034639643
-
Indinavir concentrations and St John's wort
-
Piscitelli SC, Burstein AH, Chaitt D, Alfaro RM, Falloon J (2000) Indinavir concentrations and St John's wort. Lancet 355(9203):547-548
-
(2000)
Lancet
, vol.355
, Issue.9203
, pp. 547-548
-
-
Piscitelli, S.C.1
Burstein, A.H.2
Chaitt, D.3
Alfaro, R.M.4
Falloon, J.5
-
31
-
-
0036007742
-
St Johns wort increases expression of P-glycoprotein: Implications for drug interactions
-
Hennessy M, Kelleher D, Spiers JP, Barry M, Kavanagh P, Back D, Mulcahy F, Feely J (2002) St Johns wort increases expression of P-glycoprotein: implications for drug interactions. Br J Clin Pharmacol 53(1):75-82
-
(2002)
Br J Clin Pharmacol
, vol.53
, Issue.1
, pp. 75-82
-
-
Hennessy, M.1
Kelleher, D.2
Spiers, J.P.3
Barry, M.4
Kavanagh, P.5
Back, D.6
Mulcahy, F.7
Feely, J.8
-
32
-
-
0037151365
-
Effects of St. John's wort on irinotecan metabolism
-
Mathijssen RH, Verweij J, de Bruijn P, Loos WJ, Sparreboom A (2002) Effects of St. John's wort on irinotecan metabolism. J Natl Cancer Inst 94(16):1247-1249
-
(2002)
J Natl Cancer Inst
, vol.94
, Issue.16
, pp. 1247-1249
-
-
Mathijssen, R.H.1
Verweij, J.2
De Bruijn, P.3
Loos, W.J.4
Sparreboom, A.5
-
33
-
-
4544235407
-
Drug interactions with St John's wort: Mechanisms and clinical implications
-
Mannel M (2004) Drug interactions with St John's wort: mechanisms and clinical implications. Drug Saf 27(11):773-797
-
(2004)
Drug Saf
, vol.27
, Issue.11
, pp. 773-797
-
-
Mannel, M.1
-
34
-
-
0033918159
-
Complementary/alternative medicine use in a comprehensive cancer center and the implications for oncology
-
Richardson MA, Sanders T, Palmer JL, Greisinger A, Singletary SE (2000) Complementary/alternative medicine use in a comprehensive cancer center and the implications for oncology. J Clin Oncol 18(13):2505-2514
-
(2000)
J Clin Oncol
, vol.18
, Issue.13
, pp. 2505-2514
-
-
Richardson, M.A.1
Sanders, T.2
Palmer, J.L.3
Greisinger, A.4
Singletary, S.E.5
-
35
-
-
0035035367
-
The immune system, depression and the action of antidepressants
-
Leonard BE (2001) The immune system, depression and the action of antidepressants. Prog Neuropsychopharmacol Biol Psychiatry 25(4):767-780
-
(2001)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.25
, Issue.4
, pp. 767-780
-
-
Leonard, B.E.1
-
36
-
-
0028968217
-
Contribution of proteasome-mediated proteolysis to the hierarchy of epitopes presented by major histocompatibility complex class I molecules
-
Niedermann G, Butz S, Ihlenfeldt HG, Grimm R, Lucchiari M, Hoschutzky H, Jung G, Maier B, Eichmann K (1995) Contribution of proteasome-mediated proteolysis to the hierarchy of epitopes presented by major histocompatibility complex class I molecules. Immunity 2(3):289-299
-
(1995)
Immunity
, vol.2
, Issue.3
, pp. 289-299
-
-
Niedermann, G.1
Butz, S.2
Ihlenfeldt, H.G.3
Grimm, R.4
Lucchiari, M.5
Hoschutzky, H.6
Jung, G.7
Maier, B.8
Eichmann, K.9
-
37
-
-
0033578993
-
Inhibition of NF-kappaB, clonogenicity, and radiosensitivity of human cancer cells
-
Pajonk F, Pajonk K, McBride WH (1999) Inhibition of NF-kappaB, clonogenicity, and radiosensitivity of human cancer cells. J Natl Cancer Inst 91(22):1956-1960
-
(1999)
J Natl Cancer Inst
, vol.91
, Issue.22
, pp. 1956-1960
-
-
Pajonk, F.1
Pajonk, K.2
McBride, W.H.3
-
38
-
-
0038375025
-
Regulation of apoptosis: The ubiquitous way
-
Yang Y, Yu X (2003) Regulation of apoptosis: the ubiquitous way. FASEB J 17(8):790-799
-
(2003)
FASEB J
, vol.17
, Issue.8
, pp. 790-799
-
-
Yang, Y.1
Yu, X.2
-
39
-
-
0030006904
-
Enhancement of radiosensitivity in human malignant glioma cells by hypericin in vitro
-
Zhang W, Anker L, Law RE, Hinton DR, Gopalakrishna R, Pu Q, Gundimeda U, Weiss MH, Couldwell WT (1996) Enhancement of radiosensitivity in human malignant glioma cells by hypericin in vitro. Clin Cancer Res 2(5):843-846
-
(1996)
Clin Cancer Res
, vol.2
, Issue.5
, pp. 843-846
-
-
Zhang, W.1
Anker, L.2
Law, R.E.3
Hinton, D.R.4
Gopalakrishna, R.5
Pu, Q.6
Gundimeda, U.7
Weiss, M.H.8
Couldwell, W.T.9
-
40
-
-
0025999203
-
Cytoplasmic retention, DNA binding and processing of the NF-kappa B p50 precursor are controlled by a small region in its C-terminus
-
Blank V, Kourilsky P, Israel A (1991) Cytoplasmic retention, DNA binding and processing of the NF-kappa B p50 precursor are controlled by a small region in its C-terminus. EMBO J 10(13):4159-4167
-
(1991)
EMBO J
, vol.10
, Issue.13
, pp. 4159-4167
-
-
Blank, V.1
Kourilsky, P.2
Israel, A.3
-
41
-
-
0029866197
-
Phosphorylation of p105 PEST sequence via a redox-insensitive pathway up-regulates processing of p50 NF-kappaB
-
MacKichan ML, Logeat F, Israel A (1996) Phosphorylation of p105 PEST sequence via a redox-insensitive pathway up-regulates processing of p50 NF-kappaB. J Biol Chem 271(11):6084-6091
-
(1996)
J Biol Chem
, vol.271
, Issue.11
, pp. 6084-6091
-
-
MacKichan, M.L.1
Logeat, F.2
Israel, A.3
-
42
-
-
0035816561
-
Caspase-3-mediated cleavage of the NF-kappa B subunit p65 at the NH2 terminus potentiates naphthoquinone analog-induced apoptosis
-
Kang KH, Lee KH, Kim MY, Choi KH (2001) Caspase-3-mediated cleavage of the NF-kappa B subunit p65 at the NH2 terminus potentiates naphthoquinone analog-induced apoptosis. J Biol Chem 276(27):24638-24644
-
(2001)
J Biol Chem
, vol.276
, Issue.27
, pp. 24638-24644
-
-
Kang, K.H.1
Lee, K.H.2
Kim, M.Y.3
Choi, K.H.4
|