-
1
-
-
0346122797
-
X-ray crystallographic structure determination of large asymmetric macromolecular assemblies
-
DOI 10.1016/S0076-6879(03)74008-7
-
ABRAHAMS, J. P. & BAN, N. (2003). X-ray crystallographic structure determination of large asymmetric macro-molecular assemblies. Methods in Enzymology 374, 163-188. (Pubitemid 37531810)
-
(2003)
Methods in Enzymology
, vol.374
, pp. 163-188
-
-
Abrahams, J.P.1
Ban, N.2
-
2
-
-
0030038464
-
Methods used in the structure determination of bovine mitochondrial F1 ATPase. Acta Crystallographica. Section D
-
ABRAHAMS, J. P. & LESLIE, A. G. (1996). Methods used in the structure determination of bovine mitochondrial F1 ATPase. Acta Crystallographica. Section D, Biological Crystallography 52, 30-42.
-
(1996)
Biological Crystallography
, vol.52
, pp. 30-42
-
-
Abrahams, J.P.1
Leslie, A.G.2
-
3
-
-
0024603513
-
Molecular cloning and sequencing of cDNAs encoding the entire rat fatty acid synthase
-
DOI 10.1073/pnas.86.9.3114
-
AMY, C. M., WITKOWSKI, A., NAGGERT, J., WILLIAMS, B., RANDHAWA, Z. & SMITH, S. (1989). Molecular cloning and sequencing of cDNAs encoding the entire rat fatty acid synthase. Proceedings of the National Academy of Sciences of the United States of America 86, 3114-3118. (Pubitemid 19129568)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.9
, pp. 3114-3118
-
-
Amy, C.M.1
Witkowski, A.2
Naggert, J.3
Williams, B.4
Randhawa, Z.5
Smith, S.6
-
5
-
-
17844385334
-
Structure and molecular organization of mammalian fatty acid synthase
-
DOI 10.1038/nsmb899
-
ASTURIAS, F. J., CHADICK, J. Z., CHEUNG, I. K., STARK, H., WITKOWSKI, A., JOSHI, A.K. & SMITH, S. (2005). Structure and molecular organization of mammalian fatty acid synthase. Nature Structural and Molecular Biology 12, 225-232. (Pubitemid 43079363)
-
(2005)
Nature Structural and Molecular Biology
, vol.12
, Issue.3
, pp. 225-232
-
-
Asturias, F.J.1
Chadick, J.Z.2
Cheung, I.K.3
Stark, H.4
Witkowski, A.5
Joshi, A.K.6
Smith, S.7
-
7
-
-
78650652192
-
Biosynthesis of fatty acids 2. Studies with enzymes obtained from brain
-
BRADY, R. O. (1960). Biosynthesis of fatty acids 2. Studies with enzymes obtained from brain. Journal of Biological Chemistry 235, 3099-3103.
-
(1960)
Journal of Biological Chemistry
, vol.235
, pp. 3099-3103
-
-
Brady, R.O.1
-
8
-
-
27844539339
-
Biosynthesis of fatty acids 1. Studies with enzymes obtained from liver
-
BRADY, R. O., BRADLEY, R. M. & TRAMS, E. G. (1960). Biosynthesis of fatty acids 1. Studies with enzymes obtained from liver. Journal of Biological Chemistry 235, 3093-3098.
-
(1960)
Journal of Biological Chemistry
, vol.235
, pp. 3093-3098
-
-
Brady, R.O.1
Bradley, R.M.2
Trams, E.G.3
-
9
-
-
0000239848
-
Biosynthesis of fatty acids by cell-free or water-soluble enzyme systems
-
BRADY, R. O. & GURIN, S. (1952). Biosynthesis of fatty acids by cell-free or water-soluble enzyme systems. Journal of Biological Chemistry 199, 421-431.
-
(1952)
Journal of Biological Chemistry
, vol.199
, pp. 421-431
-
-
Brady, R.O.1
Gurin, S.2
-
10
-
-
59649102440
-
Conformational flexibility of metazoan fatty acid syn-thase enables catalysis
-
BRIGNOLE, E.J., SMITH, S. & ASTURIAS, F.J. (2009). Conformational flexibility of metazoan fatty acid syn-thase enables catalysis. Nature Structural and Molecular Biology 16, 190-197.
-
(2009)
Nature Structural and Molecular Biology
, vol.16
, pp. 190-197
-
-
Brignole, E.J.1
Smith, S.2
Asturias, F.J.3
-
11
-
-
0001138751
-
Mycobacterium phlei fatty acid synthetase - A bacterial multienzyme complex
-
BRINDLEY, D. N., MATSUMUR, S. & BLOCH, K. (1969). Mycobacterium phlei fatty acid synthetase - a bacterial multienzyme complex. Nature 224, 666-669.
-
(1969)
Nature
, vol.224
, pp. 666-669
-
-
Brindley, D.N.1
Matsumur, S.2
Bloch, K.3
-
12
-
-
1242351230
-
Experimental Verification of Conformational Variation of Human Fatty Acid Synthase as Predicted by Normal Mode Analysis
-
DOI 10.1016/S0969-2126(04)00003-6
-
BRINK, J., LUDTKE, S. J., KONG, Y., WAKIL, S. J., MA, J. & CHIU, W. (2004). Experimental verification of conformational variation of human fatty acid synthase as predicted by normal mode analysis. Structure 12, 185-191. (Pubitemid 38224542)
-
(2004)
Structure
, vol.12
, Issue.2
, pp. 185-191
-
-
Brink, J.1
Ludtke, S.J.2
Kong, Y.3
Wakil, S.J.4
Ma, J.5
Chiu, W.6
-
13
-
-
0037039425
-
Quaternary structure of human fatty acid synthase by electron cryomicroscopy
-
DOI 10.1073/pnas.012589499
-
BRINK, J., LUDTKE, S. J., YANG, C. Y., GU, Z. W., WAKIL, S. J. & CHIU, W. (2002). Quaternary structure of human fatty acid synthase by electron cryomicroscopy. Proceedings of the National Academy of Sciences of the United States of America 99, 138-143. (Pubitemid 34060330)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.1
, pp. 138-143
-
-
Brink, J.1
Ludtke, S.J.2
Yang, C.-Y.3
Gu, Z.-W.4
Wakil, S.J.5
Chiu, W.6
-
14
-
-
0029905023
-
Aspergillus has distinct fatty acid synthases for primary and secondary metabolism
-
DOI 10.1073/pnas.93.25.14873
-
BROWN, D. W., ADAMS, T. H. & KELLER, N. P. (1996). Aspergillus has distinct fatty acid synthases for primary and secondary metabolism. Proceedings of the National Academy of Sciences of the United States of America 93, 14873-14877. (Pubitemid 26419062)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.25
, pp. 14873-14877
-
-
Brown, D.W.1
Adams, T.H.2
Keller, N.P.3
-
15
-
-
67649519676
-
Structural basis for different specificities of acyltransferases associated with the human cytosolic and mitochondrial fatty acid syn-thases
-
BUNKOCZI, G., MISQUITTA, S., WU, X.Q., LEE, W.H., ROJKOVA, A., KOCHAN, G., KAVANAGH, K.L., OPPERMANN, U. & SMITH, S. (2009). Structural basis for different specificities of acyltransferases associated with the human cytosolic and mitochondrial fatty acid syn-thases. Chemistry and Biology 16, 667-675.
-
(2009)
Chemistry and Biology
, vol.16
, pp. 667-675
-
-
Bunkoczi, G.1
Misquitta, S.2
Q, W.U.X.3
Lee, W.H.4
Rojkova, A.5
Kochan, G.6
Kavanagh, K.L.7
Oppermann, U.8
Smith, S.9
-
16
-
-
36049041632
-
Mechanism and substrate recognition of human holo ACP synthase
-
DOI 10.1016/j.chembiol.2007.10.013, PII S107455210700364X
-
BUNKOCZI, G., PASTA, S., JOSHI, A., WU, X., KAVANAGH, K. L., SMITH, S. & OPPERMANN, U. (2007). Mechanism and substrate recognition of human holo ACP synthase. Chemistry and Biology 14, 1243-1253. (Pubitemid 350102247)
-
(2007)
Chemistry and Biology
, vol.14
, Issue.11
, pp. 1243-1253
-
-
Bunkoczi, G.1
Pasta, S.2
Joshi, A.3
Wu, X.4
Kavanagh, K.L.5
Smith, S.6
Oppermann, U.7
-
17
-
-
8144227950
-
Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain
-
DOI 10.1073/pnas.0406901101
-
CHAKRAVARTY, B., GU, Z., CHIRALA, S. S., WAKIL, S. J. & QUIOCHO, F. A. (2004). Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain. Proceedings of the National Academy of Sciences of the United States of America 101, 15567-15572. (Pubitemid 39473528)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.44
, pp. 15567-15572
-
-
Chakravarty, B.1
Gu, Z.2
Chirala, S.S.3
Wakil, S.J.4
Quiocho, F.A.5
-
18
-
-
33947536524
-
Cryogenic (<20 K) helium cooling mitigates radiation damage to protein crystals
-
DOI 10.1107/S0907444907005264, PII S0907444907005264
-
CHINTE, U., SHAH, B., CHEN, Y. S., PINKERTON, A. A., SCHALL, C. A. & HANSON, B. L. (2007). Cryogenic (Pubitemid 46465943)
-
(2007)
Acta Crystallographica Section D: Biological Crystallography
, vol.63
, Issue.4
, pp. 486-492
-
-
Chinte, U.1
Shah, B.2
Chen, Y.-S.3
Pinkerton, A.A.4
Schall, C.A.5
Hanson, B.L.6
-
19
-
-
0030940841
-
Animal fatty acid synthase: Functional mapping and cloning and expression of the domain I constituent activities
-
DOI 10.1073/pnas.94.11.5588
-
CHIRALA, S. S., HUANG, W. Y., JAYAKUMAR, A., SAKAI, K. & WAKIL, S. J. (1997). Animal fatty acid synthase: functional mapping and cloning and expression of the domain I constituent activities. Proceedings of the National Academy of Sciences of the United States of America 94, 5588-5593. (Pubitemid 27241813)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.11
, pp. 5588-5593
-
-
Chirala, S.S.1
Huang, W.-Y.2
Jayakumar, A.3
Sakai, K.4
Wakil, S.J.5
-
20
-
-
0035853039
-
Human fatty acid synthase: Role of interdomain in the formation of catalytically active synthase dimer
-
DOI 10.1073/pnas.051635998
-
CHIRALA, S. S., JAYAKUMAR, A., GU, Z. W. & WAKIL, S. J. (2001). Human fatty acid synthase: role of interdomain in the formation of catalytically active synthase dimer. Proceedings of the National Academy of Sciences of the United States of America 98, 3104-3108. (Pubitemid 32220806)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.6
, pp. 3104-3108
-
-
Chirala, S.S.1
Jayakumar, A.2
Gu, Z.-W.3
Wakil, S.J.4
-
21
-
-
12344283741
-
Structure and function of animal fatty acid synthase
-
DOI 10.1007/s11745-004-1329-9
-
CHIRALA, S. S. & WAKIL, S. J. (2004). Structure and function of animal fatty acid synthase. Lipids 39, 1045-1053. (Pubitemid 40129046)
-
(2004)
Lipids
, vol.39
, Issue.11
, pp. 1045-1053
-
-
Chirala, S.S.1
Wakil, S.J.2
-
22
-
-
0036006782
-
Expression, purification, crystallization and preliminary X-ray analysis of the acyl carrier protein synthase (acps) from Mycobacterium tuberculosis
-
DOI 10.1107/S0907444901019874
-
CHOPRA, S., SINGH, S. K., SATI, S. P., RANGANATHAN, A. & SHARMA, A. (2002). Expression, purification, crystallization and preliminary X-ray analysis of the acyl carrier protein synthase (acpS) from Mycobacterium tuberculosis. Acta Crystallographica. Section D, Biological Crystallography 58, 179-181. (Pubitemid 34099081)
-
(2002)
Acta Crystallographica Section D: Biological Crystallography
, vol.58
, Issue.1
, pp. 179-181
-
-
Chopra, S.1
Singh, S.K.2
Sati, S.P.3
Ranganathan, A.4
Sharma, A.5
-
23
-
-
0002583957
-
Joint CCP4 and ESF-EACBM Newsletter on protein
-
COWTAN, K. (1994). Joint CCP4 and ESF-EACBM Newsletter on protein. Crystallography 31, 34-38.
-
(1994)
Crystallography
, vol.31
, pp. 34-38
-
-
Cowtan, K.1
-
24
-
-
0036894185
-
Generic representation and evaluation of properties as a function of position in reciprocal space
-
DOI 10.1107/S0021889802013420
-
COWTAN, K. (2002). Generic representation and evaluation of properties as a function of position in reciprocal space. Journal of Applied Crystallography 35, 655-663. (Pubitemid 35423527)
-
(2002)
Journal of Applied Crystallography
, vol.35
, Issue.6
, pp. 655-663
-
-
Cowtan, K.1
-
25
-
-
48649095210
-
Acyl-carrier protein-phosphopantetheinyltransferase partnerships in fungal fatty acid synthases
-
CRAWFORD, J.M., VAGSTAD, A.L., EHRLICH, K.C., UDWARY, D. W. & TOWNSEND, C. A. (2008). Acyl-carrier protein-phosphopantetheinyltransferase partnerships in fungal fatty acid synthases. Chembiochem 9, 1559-1563.
-
(2008)
Chembiochem
, vol.9
, pp. 1559-1563
-
-
Crawford, J.M.1
Vagstad, A.L.2
Ehrlich, K.C.3
Udwary, D.W.4
Townsend, C.A.5
-
26
-
-
0033213602
-
Data-collection strategies. Acta Crystallographica. Section D
-
DAUTER, Z. (1999). Data-collection strategies. Acta Crystallographica. Section D, Biological Crystallography 55, 1703-1717.
-
(1999)
Biological Crystallography
, vol.55
, pp. 1703-1717
-
-
Dauter, Z.1
-
27
-
-
27744544953
-
Use of polynuclear metal clusters in protein crystallography
-
DOI 10.1016/j.crci.2005.02.032, PII S1631074805001724
-
DAUTER, Z. (2005). Use of polynuclear metal clusters in protein crystallography. Comptes Rendus Chimie 8, 1808-1814. (Pubitemid 41600302)
-
(2005)
Comptes Rendus Chimie
, vol.8
, Issue.11-12
, pp. 1808-1814
-
-
Dauter, Z.1
-
28
-
-
0016416490
-
Fatty acid synthase from rabbit mammary gland
-
DILS, R. & CAREY, E. M. (1975). Fatty acid synthase from rabbit mammary gland. Methods in Enzymology 35, 74-83.
-
(1975)
Methods in Enzymology
, vol.35
, pp. 74-83
-
-
Dils, R.1
Carey, E.M.2
-
29
-
-
70349804291
-
Structure-function analysis of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis
-
DYM, O., ALBECK, S., PELEG, Y., SCHWARZ, A., SHAKKED, Z., BURSTEIN, Y. & ZIMHONY, O. (2009). Structure-function analysis of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis. Journal of Molecular Biology 393, 937-950.
-
(2009)
Journal of Molecular Biology
, vol.393
, pp. 937-950
-
-
Dym, O.1
Albeck, S.2
Peleg, Y.3
Schwarz, A.4
Shakked, Z.5
Burstein, Y.6
Zimhony, O.7
-
30
-
-
3042551455
-
Structure and biosynthesis of the Jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula
-
DOI 10.1016/j.chembiol.2004.03.030, PII S1074552104001474
-
EDWARDS, D. J., MARQUEZ, B. L., NOGLE, L. M., MCPHAIL, K., GOEGER, D. E., ROBERTS, M. A. & GERWICK, W. H. (2004). Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula. Chemistry and Biology 11, 817-833. (Pubitemid 38836898)
-
(2004)
Chemistry and Biology
, vol.11
, Issue.6
, pp. 817-833
-
-
Edwards, D.J.1
Marquez, B.L.2
Nogle, L.M.3
McPhail, K.4
Goeger, D.E.5
Roberts, M.A.6
Gerwick, W.H.7
-
31
-
-
0018538691
-
Identity of malonyl and palmitoyl transferase of fatty acid synthetase from yeast. 2. A comparison of active-site peptides
-
ENGESER, H., HUBNER, K., STRAUB, J. & LYNEN, F. (1979). Identity of malonyl and palmitoyl transferase of fatty acid synthetase from yeast. 2. A comparison of active-site peptides. European Journal of Biochemistry 101, 413-422.
-
(1979)
European Journal of Biochemistry
, vol.101
, pp. 413-422
-
-
Engeser, H.1
Hubner, K.2
Straub, J.3
Lynen, F.4
-
32
-
-
0034111426
-
A novel function of yeast fatty acid synthase. Subunit α is capable of self-pantetheinylation
-
DOI 10.1046/j.1432-1327.2000.01282.x
-
FICHTLSCHERER, F., WELLEIN, C., MITTAG, M. & SCHWEIZER, E. (2000). A novel function of yeast fatty acid synthase. Subunit alpha is capable of self-pantetheinylation. European Journal of Biochemistry 267, 2666-2671. (Pubitemid 30304263)
-
(2000)
European Journal of Biochemistry
, vol.267
, Issue.9
, pp. 2666-2671
-
-
Fichtlscherer, F.1
Wellein, C.2
Mittag, M.3
Schweizer, E.4
-
33
-
-
28844465191
-
An iterative type I polyketide synthase PKSN catalyzes synthesis of the decaketide alternapyrone with regio-specific octa-methylation
-
DOI 10.1016/j.chembiol.2005.09.015, PII S1074552105003108
-
FUJII, I., YOSHIDA, N., SHIMOMAKI, S., OIKAWA, H. & EBIZUKA, Y. (2005). An iterative type I polyketide syn-thase PKSN catalyzes synthesis of the decaketide alter-napyrone with regio-specific octa-methylation. Chemistry and Biology 12, 1301-1309. (Pubitemid 41779470)
-
(2005)
Chemistry and Biology
, vol.12
, Issue.12
, pp. 1301-1309
-
-
Fujii, I.1
Yoshida, N.2
Shimomaki, S.3
Oikawa, H.4
Ebizuka, Y.5
-
34
-
-
0007679488
-
On unit of mitochondrial structure and function
-
GREEN, D. E. & ODA, T. (1961). On unit of mitochondrial structure and function. Journal of Biochemistry 49, 742-757.
-
(1961)
Journal of Biochemistry
, vol.49
, pp. 742-757
-
-
Green, D.E.1
Oda, T.2
-
35
-
-
33745859340
-
Crystal structure of 2-nitropropane diox-ygenase complexed with FMN and substrate. Identification of the catalytic base
-
HA, J. Y., MIN, J. Y., LEE, S. K., KIM, H. S., KIM DO, J., KIM, K. H., LEE, H. H., KIM, H. K., YOON, H. J. & SUH, S. W. (2006). Crystal structure of 2-nitropropane diox-ygenase complexed with FMN and substrate. Identification of the catalytic base. Journal of Biological Chemistry 281, 18660-18667.
-
(2006)
Journal of Biological Chemistry
, vol.281
, pp. 18660-18667
-
-
Y, H.A.J.1
Min, J.Y.2
Lee, S.K.3
Kim, H.S.4
Kim, D.O.J.5
Kim, K.H.6
Lee, H.H.7
Kim, H.K.8
Yoon, H.J.9
Suh, S.W.10
-
36
-
-
0023089094
-
Electron microscopical structure analysis of yeast fatty-acid synthase at low resolution
-
HACKENJOS, W. A. & SCHRAMM, H. J. (1987). Electron microscopical structure analysis of yeast fatty-acid syn-thase at low resolution. Biological Chemistry Hoppe-Seyler 368, 19-36. (Pubitemid 17235177)
-
(1987)
Biological Chemistry Hoppe-Seyler
, vol.368
, Issue.1
, pp. 19-36
-
-
Hackenjos, W.-A.1
Schramm, H.J.2
-
37
-
-
0016327614
-
Three-dimensional reconstruction of individual negatively stained yeast fatty-acid synthe-tase molecules from tilt series in the electron microscope
-
HOPPE, W., GASSMANN, J., HUNSMANN, N., SCHRAMM, H. J. & STURM, M. (1974). Three-dimensional reconstruction of individual negatively stained yeast fatty-acid synthe-tase molecules from tilt series in the electron microscope. Hoppe Seylers Zeitschrift für Physiologische Chemie 355, 1483-1487.
-
(1974)
Hoppe Seylers Zeitschrift für Physiologische Chemie
, vol.355
, pp. 1483-1487
-
-
Hoppe, W.1
Gassmann, J.2
Hunsmann, N.3
Schramm, H.J.4
Sturm, M.5
-
38
-
-
84944295787
-
3-dimensional electron-microscopy of individual biological objects 3. Experimental results on yeast fatty-acid synthetase
-
HOPPE, W., SCHRAMM, H. J., STURM, M., HUNSMANN, N. & GASSMANN, J. (1976). 3-dimensional electron-microscopy of individual biological objects 3. Experimental results on yeast fatty-acid synthetase. Zeitschrift Fur Naturforschung Section a-a Journal of Physical Sciences 31, 1380-1390.
-
(1976)
Zeitschrift fur Naturforschung Section A-A Journal of Physical Sciences
, vol.31
, pp. 1380-1390
-
-
Hoppe, W.1
Schramm, H.J.2
Sturm, M.3
Hunsmann, N.4
Gassmann, J.5
-
39
-
-
0028172258
-
Amino-terminal blocking group and sequence of the animal fatty acid synthase
-
HUANG, W. Y., CHIRALA, S. S. & WAKIL, S. J. (1994). Amino-terminal blocking group and sequence of the animal fatty acid synthase. Archives of Biochemistry and Biophysics 314, 45-49.
-
(1994)
Archives of Biochemistry and Biophysics
, vol.314
, pp. 45-49
-
-
Huang, W.Y.1
Chirala, S.S.2
Wakil, S.J.3
-
40
-
-
0029906133
-
Cloning and expression of the multifunctional human fatty acid synthase and its sub-domains in Escherichia coli
-
JAYAKUMAR, A., HUANG, W. Y., RAETZ, B., CHIRALA, S. S. & WAKIL, S. J. (1996). Cloning and expression of the multifunctional human fatty acid synthase and its sub-domains in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America 93, 14509-14514.
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, pp. 14509-14514
-
-
Jayakumar, A.1
Huang, W.Y.2
Raetz, B.3
Chirala, S.S.4
Wakil, S.J.5
-
41
-
-
0019348487
-
Fatty acid synthase from red blood cells
-
JENIK, R. A. & PORTER, J. W. (1981). Fatty acid synthase from red blood cells. Methods in Enzymology 71, 97-103.
-
(1981)
Methods in Enzymology
, vol.71
, pp. 97-103
-
-
Jenik, R.A.1
Porter, J.W.2
-
42
-
-
58849092366
-
Imperfect pseudo-merohedral twinning in crystals of fungal fatty acid synthase. Acta Crystallographica. Section D
-
JENNI, S. & BAN, N. (2009). Imperfect pseudo-merohedral twinning in crystals of fungal fatty acid synthase. Acta Crystallographica. Section D, Biological Crystallography 65, 101-111.
-
(2009)
Biological Crystallography
, vol.65
, pp. 101-111
-
-
Jenni, S.1
Ban, N.2
-
43
-
-
34247383568
-
Structure of fungal fatty acid synthase and implications for iterative substrate shuttling
-
DOI 10.1126/science.1138248
-
JENNI, S., LEIBUNDGUT, M., BOEHRINGER, D., FRICK, C., MIKOLASEK, B. & BAN, N. (2007). Structure of fungal fatty acid synthase and implications for iterative substrate shuttling. Science 316, 254-261. (Pubitemid 46633098)
-
(2007)
Science
, vol.316
, Issue.5822
, pp. 254-261
-
-
Jenni, S.1
Leibundgut, M.2
Boehringer, D.3
Frick, C.4
Mikolasek, B.5
Ban, N.6
-
44
-
-
33644663441
-
Architecture of a fungal fatty acid synthase at 5 A resolution
-
DOI 10.1126/science.1123251
-
JENNI, S., LEIBUNDGUT, M., MAIER, T. & BAN, N. (2006). Architecture of a fungal fatty acid synthase at 5 A resolution. Science 311, 1263-1267. (Pubitemid 43334710)
-
(2006)
Science
, vol.311
, Issue.5765
, pp. 1263-1267
-
-
Jenni, S.1
Leibundgut, M.2
Maier, T.3
Ban, N.4
-
45
-
-
68149138671
-
Mul-timeric options for the auto-activation of the Sacch-aromyces cerevisiae FAS type i megasynthase
-
JOHANSSON, P., MULINACCI, B., KOESTLER, C., VOLLRATH, R., OESTERHELT, D. & GRININGER, M. (2009). Mul-timeric options for the auto-activation of the Sacch-aromyces cerevisiae FAS type I megasynthase. Structure 17, 1063-1074.
-
(2009)
Structure
, vol.17
, pp. 1063-1074
-
-
Johansson, P.1
Mulinacci, B.2
Koestler, C.3
Vollrath, R.4
Oesterhelt, D.5
Grininger, M.6
-
46
-
-
51349099946
-
Inhibition of the fungal fatty acid synthase type i multienzyme complex
-
JOHANSSON, P., WILTSCHI, B., KUMARI, P., KESSLER, B., VONRHEIN, C., VONCK, J., OESTERHELT, D. & GRININGER, M. (2008). Inhibition of the fungal fatty acid synthase type I multienzyme complex. Proceedings of the National Academy of Sciences of the United States of America 105, 12803-12808.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 12803-12808
-
-
Johansson, P.1
Wiltschi, B.2
Kumari, P.3
Kessler, B.4
Vonrhein, C.5
Vonck, J.6
Oesterhelt, D.7
Grininger, M.8
-
47
-
-
0037330531
-
Engineering of an active animal fatty acid synthase dimer with only one competent subunit
-
DOI 10.1016/S1074-5521(03)00023-1
-
JOSHI, A. K., RANGAN, V. S., WITKOWSKI, A. & SMITH, S. (2003). Engineering of an active animal fatty acid syn-thase dimer with only one competent subunit. Chemistry and Biology 10, 169-173. (Pubitemid 36250975)
-
(2003)
Chemistry and Biology
, vol.10
, Issue.2
, pp. 169-173
-
-
Joshi, A.K.1
Rangan, V.S.2
Witkowski, A.3
Smith, S.4
-
48
-
-
0027430939
-
Construction of a cDNA encoding the multifunctional animal fatty acid synthase and expression in Spodoptera frugiperda cells using baculoviral vectors
-
JOSHI, A. K. & SMITH, S. (1993a). Construction of a cDNA encoding the multifunctional animal fatty acid synthase and expression in Spodoptera frugiperda cells using baculoviral vectors. Biochemical Journal 296, 143-149. (Pubitemid 23344741)
-
(1993)
Biochemical Journal
, vol.296
, Issue.1
, pp. 143-149
-
-
Joshi, A.K.1
Smith, S.2
-
49
-
-
0027381395
-
Construction, expression, and characterization of a mutated animal fatty acid synthase deficient in the dehydrase function
-
JOSHI, A. K. & SMITH, S. (1993b). Construction, expression, and characterization of a mutated animal fatty acid synthase deficient in the dehydrase function. Journal of Biological Chemistry 268, 22508-22513. (Pubitemid 23318302)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.30
, pp. 22508-22513
-
-
Joshi, A.K.1
Smith, S.2
-
50
-
-
14844357601
-
Effect of modification of the length and flexibility of the acyl carrier protein-thioesterase interdomain linker on functionality of the animal fatty acid synthase
-
DOI 10.1021/bi047856r
-
JOSHI, A. K., WITKOWSKI, A., BERMAN, H. A., ZHANG, L. & SMITH, S. (2005). Effect of modification of the length and flexibility of the acyl carrier protein-thioesterase interdomain linker on functionality of the animal fatty acid synthase. Biochemistry 44, 4100-4107. (Pubitemid 40358063)
-
(2005)
Biochemistry
, vol.44
, Issue.10
, pp. 4100-4107
-
-
Joshi, A.K.1
Witkowski, A.2
Berman, H.A.3
Zhang, L.4
Smith, S.5
-
51
-
-
0019346232
-
Fatty acid synthase from Cephalosporium caerulens
-
KAWAGUCHI, A., TOMODA, H., OKUDA, S. & OMURA, S. (1981). Fatty acid synthase from Cephalosporium caerulens. Methods in Enzymology 71, 117-120.
-
(1981)
Methods in Enzymology
, vol.71
, pp. 117-120
-
-
Kawaguchi, A.1
Tomoda, H.2
Okuda, S.3
Omura, S.4
-
52
-
-
0019347782
-
Fatty acid synthase from pig liver
-
KIM, I. C., NEUDAHL, G. & DEAL, JR., W. C. (1981). Fatty acid synthase from pig liver. Methods in Enzymology 71, 79-85.
-
(1981)
Methods in Enzymology
, vol.71
, pp. 79-85
-
-
Kim, I.C.1
Neudahl, G.2
Deal Jr., W.C.3
-
53
-
-
10644295401
-
The structure of (3R)-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Pseudomonas aeruginosa
-
DOI 10.1074/jbc.M408105200
-
KIMBER, M. S., MARTIN, F., LU, Y., HOUSTON, S., VEDADI, M., DHARAMSI, A., FIEBIG, K. M., SCHMID, M. & ROCK, C. O. (2004). The structure of (3R)-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Pseudomonas aeruginosa. Journal of Biological Chemistry 279, 52593-52602. (Pubitemid 39656636)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.50
, pp. 52593-52602
-
-
Kimber, M.S.1
Martin, F.2
Lu, Y.3
Houston, S.4
Vedadi, M.5
Dharamsi, A.6
Fiebig, K.M.7
Schmid, M.8
Rock, C.O.9
-
54
-
-
0023676411
-
Structure of fatty acid synthetase from the Harderian gland of guinea pig. Proteolytic dissection and electron microscopic studies
-
KITAMOTO, T., NISHIGAI, M., SASAKI, T. & IKAI, A. (1988). Structure of fatty acid synthetase from the Harderian gland of guinea pig. Proteolytic dissection and electron microscopic studies. Journal of Molecular Biology 203, 183-195.
-
(1988)
Journal of Molecular Biology
, vol.203
, pp. 183-195
-
-
Kitamoto, T.1
Nishigai, M.2
Sasaki, T.3
Ikai, A.4
-
55
-
-
33947301746
-
The relationship of coenzyme A to lipide synthesis. I. Experiments with yeast
-
KLEIN, H. P. & LIPMANN, F. (1953a). The relationship of coenzyme A to lipide synthesis. I. Experiments with yeast. Journal of Biological Chemistry 203, 95-99.
-
(1953)
Journal of Biological Chemistry
, vol.203
, pp. 95-99
-
-
Klein, H.P.1
Lipmann, F.2
-
56
-
-
34547134072
-
The relationship of coenzyme A to lipide synthesis. II. Experiments with rat liver
-
KLEIN, H. P. & LIPMANN, F. (1953b). The relationship of coenzyme A to lipide synthesis. II. Experiments with rat liver. Journal of Biological Chemistry 203, 101-108.
-
(1953)
Journal of Biological Chemistry
, vol.203
, pp. 101-108
-
-
Klein, H.P.1
Lipmann, F.2
-
57
-
-
0024315260
-
The mechanism of biotin-depen-dent enzymes
-
KNOWLES, J. R. (1989). The mechanism of biotin-depen-dent enzymes. Annual Review of Biochemistry 58, 195-221.
-
(1989)
Annual Review of Biochemistry
, vol.58
, pp. 195-221
-
-
Knowles, J.R.1
-
58
-
-
33645807617
-
Conformational switches modulate protein interactions in peptide antibiotic synthetases
-
KOGLIN, A., MOFID, M. R., LOHR, F., SCHAFER, B., ROGOV, V. V., BLUM, M. M., MITTAG, T., MARAHIEL, M. A., BERNHARD, F. & DOTSCH, V. (2006). Conformational switches modulate protein interactions in peptide antibiotic synthetases. Science 312, 273-276.
-
(2006)
Science
, vol.312
, pp. 273-276
-
-
Koglin, A.1
Mofid, M.R.2
Lohr, F.3
Schafer, B.4
Rogov, V.V.5
Blum, M.M.6
Mittag, T.7
Marahiel, M.A.8
Bernhard, F.9
Dotsch, V.10
-
59
-
-
0019344130
-
Fatty acid synthase from the uropygial gland of goose
-
KOLATTUKUDY, P.E., POULOSE, A.J. & BUCKNER, J.S. (1981). Fatty acid synthase from the uropygial gland of goose. Methods in Enzymology 71, 103-109.
-
(1981)
Methods in Enzymology
, vol.71
, pp. 103-109
-
-
Kolattukudy, P.E.1
Poulose, A.J.2
Buckner, J.S.3
-
60
-
-
0031454799
-
Utility of butvar support film and methylamine tungstate stain in three- dimensional electron microscopy: Agreement between stain and frozen-hydrated reconstructions
-
DOI 10.1006/jsbi.1997.3911
-
KOLODZIEJ, S. J., PENCZEK, P. A. & STOOPS, J. K. (1997). Utility of Butvar support film and methylamine tung-state stain in three-dimensional electron microscopy: agreement between stain and frozen-hydrated reconstructions. Journal of Structural Biology 120, 158-167. (Pubitemid 28055752)
-
(1997)
Journal of Structural Biology
, vol.120
, Issue.2
, pp. 158-167
-
-
Kolodziej, S.J.1
Penczek, P.A.2
Stoops, J.K.3
-
61
-
-
11844302312
-
Crystal structure of 2-enoyl-CoA hydratase 2 from human peroxisomal multifunctional enzyme type 2
-
DOI 10.1016/j.jmb.2004.11.009, PII S0022283604014354
-
KOSKI, K. M., HAAPALAINEN, A. M., HILTUNEN, J. K. & GLUMOFF, T. (2005). Crystal structure of 2-enoyl-CoA hydratase 2 from human peroxisomal multifunctional enzyme type 2. Journal of Molecular Biology 345, 1157-1169. (Pubitemid 40092231)
-
(2005)
Journal of Molecular Biology
, vol.345
, Issue.5
, pp. 1157-1169
-
-
Kristian Koski, M.1
Haapalainen, A.M.2
Hiltunen, J.K.3
Glumoff, T.4
-
62
-
-
2642582616
-
A two-domain structure of one subunit explains unique features of eukaryotic hydratase 2
-
DOI 10.1074/jbc.M400293200
-
KOSKI, M. K., HAAPALAINEN, A. M., HILTUNEN, J. K. & GLUMOFF, T. (2004). A two-domain structure of one subunit explains unique features of eukaryotic hydratase 2. Journal of Biological Chemistry 279, 24666-24672. (Pubitemid 38725334)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.23
, pp. 24666-24672
-
-
Koski, M.K.1
Haapalainen, A.M.2
Hiltunen, J.K.3
Glumoff, T.4
-
63
-
-
84886635334
-
Localization of the central and peripheral SH-groups on the same polypeptide chain of yeast fatty acid synthetase
-
KRESZE, G. B., OESTERHELT, D., LYNEN, F., CASTORPH, H. & SCHWEIZER, E. (1976). Localization of the central and peripheral SH-groups on the same polypeptide chain of yeast fatty acid synthetase. Biochemical and Biophysical Research Communications 69, 893-899.
-
(1976)
Biochemical and Biophysical Research Communications
, vol.69
, pp. 893-899
-
-
Kresze, G.B.1
Oesterhelt, D.2
Lynen, F.3
Castorph, H.4
Schweizer, E.5
-
64
-
-
0019345611
-
Fatty acid synthase from lactating bovine mammary gland
-
KUMAR, S. & DODDS, P. F. (1981). Fatty acid synthase from lactating bovine mammary gland. Methods in Enzymology 71, 86-97.
-
(1981)
Methods in Enzymology
, vol.71
, pp. 86-97
-
-
Kumar, S.1
Dodds, P.F.2
-
65
-
-
34247353309
-
Structural basis for substrate delivery by acyl carrier protein in the yeast fatty acid synthase
-
DOI 10.1126/science.1138249
-
LEIBUNDGUT, M., JENNI, S., FRICK, C. & BAN, N. (2007). Structural basis for substrate delivery by acyl carrier protein in the yeast fatty acid synthase. Science 316, 288-290. (Pubitemid 46633107)
-
(2007)
Science
, vol.316
, Issue.5822
, pp. 288-290
-
-
Leibundgut, M.1
Jenni, S.2
Frick, C.3
Ban, N.4
-
66
-
-
34347236451
-
Visualizing flexibility at molecular resolution: Analysis of heterogeneity in single-particle electron microscopy reconstructions
-
DOI 10.1146/annurev.biophys.36.040306.132742
-
LESCHZINER, A. E. & NOGALES, E. (2007). Visualizing flexibility at molecular resolution: analysis of heterogeneity in single-particle electron microscopy reconstructions. Annual Review of Biophysics and Biomolecular Structure 36, 43-62. (Pubitemid 46998109)
-
(2007)
Annual Review of Biophysics and Biomolecular Structure
, vol.36
, pp. 43-62
-
-
Leschziner, A.E.1
Nogales, E.2
-
67
-
-
0017805075
-
Properties of the thioesterase component obtained by limited trypsinization of the fatty acid synthetase multienzyme complex
-
LIN, C. Y. & SMITH, S. (1978). Properties of the thioester-ase component obtained by limited trypsinization of the fatty acid synthetase multienzyme complex. Journal of Biological Chemistry 253, 1954-1962. (Pubitemid 8299522)
-
(1978)
Journal of Biological Chemistry
, vol.253
, Issue.6
, pp. 1954-1962
-
-
Lin, C.Y.1
-
68
-
-
0019585554
-
Purification and crystallization of rat liver fatty acid synthetase
-
LINN, T. C. (1981). Purification and crystallization of rat liver fatty acid synthetase. Archives of Biochemistry and Biophysics 209, 613-619.
-
(1981)
Archives of Biochemistry and Biophysics
, vol.209
, pp. 613-619
-
-
Linn, T.C.1
-
69
-
-
34147098650
-
The Crystal Structure of Yeast Fatty Acid Synthase, a Cellular Machine with Eight Active Sites Working Together
-
DOI 10.1016/j.cell.2007.03.013, PII S0092867407003297
-
LOMAKIN, I. B., XIONG, Y. & STEITZ, T. A. (2007). The crystal structure of yeast fatty acid synthase, a cellular machine with eight active sites working together. Cell 129, 319-332. (Pubitemid 46574968)
-
(2007)
Cell
, vol.129
, Issue.2
, pp. 319-332
-
-
Lomakin, I.B.1
Xiong, Y.2
Steitz, T.A.3
-
70
-
-
0011076522
-
Functional group of coenzyme A and its metabolic relations, especially in the fatty acid cycle
-
LYNEN, F. (1953). Functional group of coenzyme A and its metabolic relations, especially in the fatty acid cycle. Federation Proceedings 12, 683-691.
-
(1953)
Federation Proceedings
, vol.12
, pp. 683-691
-
-
Lynen, F.1
-
71
-
-
0000889230
-
Biosynthesis of saturated fatty acids
-
LYNEN, F. (1961). Biosynthesis of saturated fatty acids. Federation Proceedings 20, 941-951.
-
(1961)
Federation Proceedings
, vol.20
, pp. 941-951
-
-
Lynen, F.1
-
72
-
-
7944238371
-
The pathway from 'activated acetic acid' to the terpenes and fatty acids
-
Amsterdam: Elsevier
-
LYNEN, F. (1964). The pathway from 'activated acetic acid' to the terpenes and fatty acids. In Nobel Lectures, Physiology or Medicine 1963-1970. Amsterdam: Elsevier.
-
(1964)
Nobel Lectures, Physiology or Medicine 1963-1970
-
-
Lynen, F.1
-
73
-
-
0014057187
-
Role of biotin-dependent carboxylations in biosynthetic reactions - 3rd Jubilee Lecture
-
LYNEN, F. (1967). Role of biotin-dependent carboxylations in biosynthetic reactions - 3rd Jubilee Lecture. BiochemicalJournal102, 381-400.
-
(1967)
BiochemicalJournal102
, pp. 381-400
-
-
Lynen, F.1
-
74
-
-
0019164234
-
On the structure of fatty acid synthetase of yeast
-
LYNEN, F. (1980). On the structure of fatty acid synthetase of yeast. European Journal of Biochemisty 112, 431-442. (Pubitemid 11176268)
-
(1980)
European Journal of Biochemistry
, vol.112
, Issue.3
, pp. 431-442
-
-
Lynen, F.1
-
75
-
-
0011078764
-
Role of coenzyme A in fatty acid metabolism
-
MAHLER, H. R. (1953). Role of coenzyme A in fatty acid metabolism. Federation Proceedings 12, 694-702.
-
(1953)
Federation Proceedings
, vol.12
, pp. 694-702
-
-
Mahler, H.R.1
-
76
-
-
33644697200
-
Architecture of mammalian fatty acid synthase at 4.5 a resolution
-
DOI 10.1126/science.1123248
-
MAIER, T., JENNI, S. & BAN, N. (2006). Architecture of mammalian fatty acid synthase at 4-5 A resolution. Science 311, 1258-1262. (Pubitemid 43334709)
-
(2006)
Science
, vol.311
, Issue.5765
, pp. 1258-1262
-
-
Maier, T.1
Jenni, S.2
Ban, N.3
-
77
-
-
51149098989
-
The crystal structure of a mammalian fatty acid synthase
-
MAIER, T., LEIBUNDGUT, M. & BAN, N. (2008). The crystal structure of a mammalian fatty acid synthase. Science 321, 1315-1322.
-
(2008)
Science
, vol.321
, pp. 1315-1322
-
-
Maier, T.1
Leibundgut, M.2
Ban, N.3
-
78
-
-
0000198203
-
Acyl carrier protein. IV. The Identification of 4k-phos-phopantetheine as the prosthetic group of the acyl carrier protein
-
MAJERUS, P. W., ALBERTS, A. W. & VAGELOS, P. R. (1965). Acyl carrier protein. IV. The Identification of 4k-phos-phopantetheine as the prosthetic group of the acyl carrier protein. Proceedings of the National Academy of Sciences of the United States of America 53, 410-417.
-
(1965)
Proceedings of the National Academy of Sciences of the United States of America
, vol.53
, pp. 410-417
-
-
Majerus, P.W.1
Alberts, A.W.2
Vagelos, P.R.3
-
79
-
-
0011835420
-
Fatty acid synthesis in adipose tissue. I. Purification and properties of a long chain fatty acid-synthesizing system
-
MARTIN, D. B., HORNING, M. G. & VAGELOS, P. R. (1961). Fatty acid synthesis in adipose tissue. I. Purification and properties of a long chain fatty acid-synthesizing system. Journal of Biological Chemistry 236, 663-668.
-
(1961)
Journal of Biological Chemistry
, vol.236
, pp. 663-668
-
-
Martin, D.B.1
Horning, M.G.2
Vagelos, P.R.3
-
80
-
-
0036917889
-
SAM (dependent) I AM: The S-adenosylmethionine-dependent methyltransferase fold
-
DOI 10.1016/S0959-440X(02)00391-3
-
MARTIN, J. L. & MCMILLAN, F. M. (2002). SAM (dependent) I AM: the S-adenosylmethionine-dependent methyl-transferase fold. Current Opinion in Structural Biology 12, 783-793. (Pubitemid 36009496)
-
(2002)
Current Opinion in Structural Biology
, vol.12
, Issue.6
, pp. 783-793
-
-
Martin, J.L.1
McMillan, F.M.2
-
81
-
-
0019545002
-
The isolation and characterization of fatty-acid-synthetase messenger-RNA from rat mammary-gland
-
MATTICK, J. S., ZEHNER, Z. E., CALABRO, M. A. & WAKIL, S. J. (1981). The isolation and characterization of fatty-acid-synthetase messenger-RNA from rat mammary-gland. European Journal of Biochemistry 114, 643-651.
-
(1981)
European Journal of Biochemistry
, vol.114
, pp. 643-651
-
-
Mattick, J.S.1
Zehner, Z.E.2
Calabro, M.A.3
Wakil, S.J.4
-
82
-
-
33947321097
-
Reduction of X-ray-induced radiation damage of macromolecular crystals by data collection at 15 K: A systematic study
-
DOI 10.1107/S0907444906053261, PII S0907444906053261
-
MEENTS, A., WAGNER, A., SCHNEIDER, R., PRADERVAND, C., POHL, E. & SCHULZE-BRIESE, C. (2007). Reduction of X-ray-induced radiation damage of macromolecular crystals by data collection at 15 K: a systematic study. Acta Crystallographica. Section D, Biological Crystallography 63, 302-309. (Pubitemid 46438523)
-
(2007)
Acta Crystallographica Section D: Biological Crystallography
, vol.63
, Issue.3
, pp. 302-309
-
-
Meents, A.1
Wagner, A.2
Schneider, R.3
Pradervand, C.4
Pohl, E.5
Schulze-Briese, C.6
-
83
-
-
0024239166
-
Primary structure of the multifunctional α subunit protein of yeast fatty acid synthase derived from FAS2 gene sequence
-
MOHAMED, A. H., CHIRALA, S. S., MODY, N. H., HUANG, W. Y. & WAKIL, S. J. (1988). Primary structure of the multifunctional alpha subunit protein of yeast fatty acid synthase derived from FAS2 gene sequence. Journal of Biological Chemistry 263, 12315-12325. (Pubitemid 19000410)
-
(1988)
Journal of Biological Chemistry
, vol.263
, Issue.25
, pp. 12315-12325
-
-
Mohamed, A.H.1
Chirala, S.S.2
Mody, N.H.3
Huang, W.-Y.4
Wakil, S.J.5
-
84
-
-
0034141305
-
The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90
-
DOI 10.1016/S1074-5521(00)00075-2
-
MOLNAR, I., SCHUPP, T., ONO, M., ZIRKLE, R., MILNAMOW, M., NOWAK-THOMPSON, B., ENGEL, N., TOUPET, C., STRATMANN, A., CYR, D. D., GORLACH, J., MAYO, J. M., HU, A., GOFF, S., SCHMID, J. & LIGON, J. M. (2000). The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90. Chemistry and Biology 7, 97-109. (Pubitemid 30086836)
-
(2000)
Chemistry and Biology
, vol.7
, Issue.2
, pp. 97-109
-
-
Molnar, I.1
Schupp, T.2
Ono, M.3
Zirkle, R.E.4
Milnamow, M.5
Nowak-Thompson, B.6
Engel, N.7
Toupet, C.8
Stratmann, A.9
Cyr, D.D.10
Gorlach, J.11
Mayo, J.M.12
Hu, A.13
Goff, S.14
Schmid, J.15
Ligon, J.M.16
-
85
-
-
35548958606
-
Strategies for crystallization and structure determination of very large macromolecular assemblies
-
DOI 10.1016/j.sbi.2007.09.004, PII S0959440X07001443, Carbohydrates and glycoconjugates / Biophysical methods
-
MUELLER, M., JENNI, S. & BAN, N. (2007). Strategies for crystallization and structure determination of very large macromolecular assemblies. Current Opinion in Structural Biology 17, 572-579. (Pubitemid 350019015)
-
(2007)
Current Opinion in Structural Biology
, vol.17
, Issue.5
, pp. 572-579
-
-
Mueller, M.1
Jenni, S.2
Ban, N.3
-
86
-
-
0016418231
-
Fatty acid syn-thase from pigeon liver
-
MUESING, R. A. & PORTER, J. W. (1975). Fatty acid syn-thase from pigeon liver. Methods in Enzymology 35, 45-59.
-
(1975)
Methods in Enzymology
, vol.35
, pp. 45-59
-
-
Muesing, R.A.1
Porter, J.W.2
-
87
-
-
0036375898
-
Medium-chain dehydrogenases/reductases (MDR): Family characterizations including genome comparisons and active site modelling
-
DOI 10.1046/j.1432-1033.2002.03114.x
-
NORDLING, E., JORNVALL, H. & PERSSON, B. (2002). Medium-chain dehydrogenases/reductases (MDR). Family characterizations including genome comparisons and active site modeling. European Journal of Biochemistry 269, 4267-4276. (Pubitemid 35033496)
-
(2002)
European Journal of Biochemistry
, vol.269
, Issue.17
, pp. 4267-4276
-
-
Nordling, E.1
Jornvall, H.2
Persson, B.3
-
88
-
-
33744460734
-
Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography
-
DOI 10.1107/S0907444906009474
-
OEFNER, C., SCHULZ, H., D'ARCY, A. & DALE, G. E. (2006). Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography. Acta Crystallographica. Section D, Biological Crystallography 62, 613-618. (Pubitemid 43806639)
-
(2006)
Acta Crystallographica Section D: Biological Crystallography
, vol.62
, Issue.6
, pp. 613-618
-
-
Oefner, C.1
Schulz, H.2
D'Arcy, A.3
Dale, G.E.4
-
89
-
-
0014552289
-
Crystallization of a multienzyme complex: Fatty acid synthetase from yeast
-
OESTERHELT, D., BAUER, H. & LYNEN, F. (1969). Crystallization of a multienzyme complex: fatty acid synthetase from yeast. Proceedings of the National Academy of Sciences of the United States of America 63, 1377-1382.
-
(1969)
Proceedings of the National Academy of Sciences of the United States of America
, vol.63
, pp. 1377-1382
-
-
Oesterhelt, D.1
Bauer, H.2
Lynen, F.3
-
90
-
-
0035085234
-
Structures of β-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery
-
DOI 10.1016/S0969-2126(01)00583-4, PII S0969212601005834
-
OLSEN, J. G., KADZIOLA, A., VON WETTSTEIN-KNOWLES, P., SIGGAARD-ANDERSEN, M. & LARSEN, S. (2001). Structures of beta-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery. Structure 9, 233-243. (Pubitemid 32245874)
-
(2001)
Structure
, vol.9
, Issue.3
, pp. 233-243
-
-
Olsen, J.G.1
Kadziola, A.2
Von Wettstein-Knowles, P.3
Siggaard-Andersen, M.4
Larsen, S.5
-
91
-
-
0034662753
-
Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites
-
PARRIS, K. D., LIN, L., TAM, A., MATHEW, R., HIXON, J., STAHL, M., FRITZ, C.C., SEEHRA, J. & SOMERS, W. S. (2000). Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites. Structure 8, 883-895.
-
(2000)
Structure
, vol.8
, pp. 883-895
-
-
Parris, K.D.1
Lin, L.2
Tam, A.3
Mathew, R.4
Hixon, J.5
Stahl, M.6
Fritz, C.C.7
Seehra, J.8
Somers, W.S.9
-
92
-
-
34547672758
-
Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat
-
DOI 10.1038/nsmb1265, PII NSMB1265
-
PEMBLE, C.W.T., JOHNSON, L.C., KRIDEL, S.J. & LOWTHER, W. T. (2007). Crystal structure of the thioes-terase domain of human fatty acid synthase inhibited by Orlistat. Nature Structural and Molecular Biology 14, 704-709. (Pubitemid 47220052)
-
(2007)
Nature Structural and Molecular Biology
, vol.14
, Issue.8
, pp. 704-709
-
-
Pemble IV, C.W.1
Johnson, L.C.2
Kridel, S.J.3
Lowther, W.T.4
-
93
-
-
0026521233
-
Three-dimensional reconstruction of single particles embedded in ice
-
PENCZEK, P., RADERMACHER, M. & FRANK, J. (1992). Three-dimensional reconstruction of single particles embedded in ice. Ultramicroscopy 40, 33-53.
-
(1992)
Ultramicroscopy
, vol.40
, pp. 33-53
-
-
Penczek, P.1
Radermacher, M.2
Frank, J.3
-
94
-
-
0026079562
-
Domains, motifs, and linkers in 2-oxo acid dehydrogenase multienzyme complexes: A paradigm in the design of a multifunctional protein
-
PERHAM, R. N. (1991). Domains, motifs, and linkers in 2-oxo acid dehydrogenase multienzyme complexes: a paradigm in the design of a multifunctional protein. Biochemistry 30, 8501-8512.
-
(1991)
Biochemistry
, vol.30
, pp. 8501-8512
-
-
Perham, R.N.1
-
95
-
-
0033790516
-
Swinging arms and swinging domains in multifunctional enzymes: Catalytic machines for multistep reactions
-
PERHAM, R. N. (2000). Swinging arms and swinging domains in multifunctional enzymes: catalytic machines for multistep reactions. Annual Review of Biochemistry 69, 961-1004.
-
(2000)
Annual Review of Biochemistry
, vol.69
, pp. 961-1004
-
-
Perham, R.N.1
-
96
-
-
0037324955
-
Coenzyme-based functional assignments of short-chain dehydrogenases/ reductases (SDRs)
-
DOI 10.1016/S0009-2797(02)00223-5, PII S0009279702002235
-
PERSSON, B., KALLBERG, Y., OPPERMANN, U. & JORNVALL, H. (2003). Coenzyme-based functional assignments of short-chain dehydrogenases/reductases (SDRs). Chemico-Biological Interactions 143-144, 271-278. (Pubitemid 36253590)
-
(2003)
Chemico-Biological Interactions
, vol.143-144
, pp. 271-278
-
-
Persson, B.1
Kallberg, Y.2
Oppermann, U.3
Jornvall, H.4
-
97
-
-
0014752491
-
Small-angle X-ray scattering study of fatty acid synthetase from yeast
-
PILZ, I., HERBST, M., KRATKY, O., OESTERHELT, D. & LYNEN, F. (1970). Small-angle X-ray scattering study of fatty acid synthetase from yeast. European Journal of Biochemistry 13, 55-64.
-
(1970)
European Journal of Biochemistry
, vol.13
, pp. 55-64
-
-
Pilz, I.1
Herbst, M.2
Kratky, O.3
Oesterhelt, D.4
Lynen, F.5
-
98
-
-
0015877605
-
The specificity of yeast fatty-acid synthetase with respect to the "priming" substrate. Decanoyl-coA and derivatives as "primers" of fatty-acid synthesis in vitro
-
PIRSON, W., SCHUHMANN, L. & LYNEN, F. (1973). The specificity of yeast fatty-acid synthetase with respect to the "priming" substrate. Decanoyl-coA and derivatives as "primers" of fatty-acid synthesis in vitro. European Journal of Biochemistry 36, 16-24.
-
(1973)
European Journal of Biochemistry
, vol.36
, pp. 16-24
-
-
Pirson, W.1
Schuhmann, L.2
Lynen, F.3
-
99
-
-
38049136859
-
A mammalian type i fatty acid synthase acyl carrier protein domain does not sequester acyl chains
-
PLOSKON, E., ARTHUR, C. J., EVANS, S. E., WILLIAMS, C., CROSBY, J., SIMPSON, T. J. & CRUMP, M. P. (2008). A mammalian type I fatty acid synthase acyl carrier protein domain does not sequester acyl chains. Journal of Biological Chemistry 283, 518-528.
-
(2008)
Journal of Biological Chemistry
, vol.283
, pp. 518-528
-
-
Ploskon, E.1
Arthur, C.J.2
Evans, S.E.3
Williams, C.4
Crosby, J.5
Simpson, T.J.6
Crump, M.P.7
-
100
-
-
0035980230
-
Structure of β-ketoacyl-[acyl carrier protein] reductase from Escherichia coli: Negative cooperativity and its structural basis
-
DOI 10.1021/bi010737g
-
PRICE, A. C., ZHANG, Y. M., ROCK, C. O. & WHITE, S. W. (2001). Structure of beta-ketoacyl-[acyl carrier protein] reductase from Escherichia coli: negative cooperativity and its structural basis. Biochemistry 40, 12772-12781. (Pubitemid 33026624)
-
(2001)
Biochemistry
, vol.40
, Issue.43
, pp. 12772-12781
-
-
Price, A.C.1
Zhang, Y.-M.2
Rock, C.O.3
White, S.W.4
-
101
-
-
1542602992
-
Cofactor-induced conformational rearrangements establish a catalytically competent active site and a proton relay conduit in FabG
-
DOI 10.1016/j.str.2004.02.008, PII S0969212604000504
-
PRICE, A. C., ZHANG, Y. M., ROCK, C. O. & WHITE, S. W. (2004). Cofactor-induced conformational rearrangements establish a catalytically competent active site and a proton relay conduit in FabG. Structure 12, 417-428. (Pubitemid 38353063)
-
(2004)
Structure
, vol.12
, Issue.3
, pp. 417-428
-
-
Price, A.C.1
Zhang, Y.-M.2
Rock, C.O.3
White, S.W.4
-
102
-
-
0013824259
-
Studies on mechanism of fatty acid synthesis 14. Prosthetic group of acyl carrier protein and mode of its attachment to protein
-
PUGH, E. L. & WAKIL, S. J. (1965). Studies on mechanism of fatty acid synthesis 14. Prosthetic group of acyl carrier protein and mode of its attachment to protein. Journal of Biological Chemistry 240, 4727-4733.
-
(1965)
Journal of Biological Chemistry
, vol.240
, pp. 4727-4733
-
-
Pugh, E.L.1
Wakil, S.J.2
-
103
-
-
84985231782
-
Three-dimensional reconstruction from a single-exposure random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli
-
RADERMACHER, M., WAGENKNECHT, T., VERSCHOOR, A. & FRANK, J. (1987). Three-dimensional reconstruction from a single-exposure, random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli. Journal of Microscopy 146, 113-136.
-
(1987)
Journal of Microscopy
, vol.146
, pp. 113-136
-
-
Radermacher, M.1
Wagenknecht, T.2
Verschoor, A.3
Frank, J.4
-
104
-
-
0024529299
-
Conformational flexibility and folding of synthetic peptides representing an interdomain segment of polypeptide chain in the pyruvate dehydrogenase multienzyme complex of Escherichia coli
-
RADFORD, S. E., LAUE, E. D., PERHAM, R. N., MARTIN, S. R. & APPELLA, E. (1989). Conformational flexibility and folding of synthetic peptides representing an inter-domain segment of polypeptide chain in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. Journal of Biological Chemistry 264, 767-775. (Pubitemid 19038051)
-
(1989)
Journal of Biological Chemistry
, vol.264
, Issue.2
, pp. 767-775
-
-
Radford, S.E.1
Laue, E.D.2
Perham, R.N.3
Martin, S.R.4
Appella, E.5
-
105
-
-
33845970262
-
Structure of acyl carrier protein bound to FabI, the FASII enoyl reductase from Escherichia coli
-
DOI 10.1074/jbc.M608758200
-
RAFI, S., NOVICHENOK, P., KOLAPPAN, S., ZHANG, X., STRATTON, C. F., RAWAT, R., KISKER, C., SIMMERLING, C. & TONGE, P. J. (2006). Structure of acyl carrier protein bound to FabI, the FASII enoyl reductase from Escherichia coli. Journal of Biological Chemistry 281, 39285-39293. (Pubitemid 46041887)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.51
, pp. 39285-39293
-
-
Rafi, S.1
Novichenok, P.2
Kolappan, S.3
Zhang, X.4
Stratton, C.F.5
Rawat, R.6
Kisker, C.7
Simmerling, C.8
Tonge, P.J.9
-
106
-
-
0035845638
-
Mapping the functional topology of the animal fatty acid synthase by mutant complementation in vitro
-
DOI 10.1021/bi015535z
-
RANGAN, V. S., JOSHI, A. K. & SMITH, S. (2001). Mapping the functional topology of the animal fatty acid synthase by mutant complementation in vitro. Biochemistry 40, 10792-10799. (Pubitemid 32835020)
-
(2001)
Biochemistry
, vol.40
, Issue.36
, pp. 10792-10799
-
-
Rangan, V.S.1
Joshi, A.K.2
Smith, S.3
-
107
-
-
0030911617
-
Alteration of the substrate specificity of the malonyl-CoA/acetyl- CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue
-
DOI 10.1074/jbc.272.18.11975
-
RANGAN, V. S. & SMITH, S. (1997). Alteration of the substrate specificity of the malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue. Journal of Biological Chemistry 272, 11975-11978. (Pubitemid 27202772)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.18
, pp. 11975-11978
-
-
Rangan, V.S.1
Smith, S.2
-
108
-
-
0000815924
-
The utilization of acetic acid for fatty acid synthesis
-
RITTENBERG, D. & BLOCH, K. (1944). The utilization of acetic acid for fatty acid synthesis. Journal of Biological Chemistry 154, 311-312.
-
(1944)
Journal of Biological Chemistry
, vol.154
, pp. 311-312
-
-
Rittenberg, D.1
Bloch, K.2
-
110
-
-
0019343032
-
Fatty acid synthase from human liver
-
RONCARI, D. A. (1981). Fatty acid synthase from human liver. Methods in Enzymology 71, 73-79.
-
(1981)
Methods in Enzymology
, vol.71
, pp. 73-79
-
-
Roncari, D.A.1
-
111
-
-
0015501810
-
Acyl carrier protein. XIX. Amino acid sequence of liver fatty acid synthetase peptides containing 4k-phospho-pantetheine
-
RONCARI, D. A., BRADSHAW, R. A. & VAGELOS, P. R. (1972). Acyl carrier protein. XIX. Amino acid sequence of liver fatty acid synthetase peptides containing 4k-phospho-pantetheine. Journal of Biological Chemistry 247, 6234-6242.
-
(1972)
Journal of Biological Chemistry
, vol.247
, pp. 6234-6242
-
-
Roncari, D.A.1
Bradshaw, R.A.2
Vagelos, P.R.3
-
112
-
-
0036277954
-
X-ray crystallographic studies on butyryl-ACP reveal flexibility of the structure around a putative acyl chain binding site
-
DOI 10.1016/S0969-2126(02)00775-X, PII S096921260200775X
-
ROUJEINIKOVA, A., BALDOCK, C., SIMON, W. J., GILROY, J., BAKER, P. J., STUITJE, A. R., RICE, D. W., SLABAS, A. R. & RAFFERTY, J. B. (2002). X-ray crystallographic studies on butyryl-ACP reveal flexibility of the structure around a putative acyl chain binding site. Structure 10, 825-835. (Pubitemid 34628711)
-
(2002)
Structure
, vol.10
, Issue.6
, pp. 825-835
-
-
Roujeinikova, A.1
Baldock, C.2
Simon, W.J.3
Gilroy, J.4
Baker, P.J.5
Stuitje, A.R.6
Rice, D.W.7
Slabas, A.R.8
Rafferty, J.B.9
-
113
-
-
33751512907
-
Structural Studies of Fatty Acyl-(Acyl Carrier Protein) Thioesters Reveal a Hydrophobic Binding Cavity that Can Expand to Fit Longer Substrates
-
DOI 10.1016/j.jmb.2006.09.049, PII S0022283606012733
-
ROUJEINIKOVA, A., SIMON, W. J., GILROY, J., RICE, D. W., RAFFERTY, J. B. & SLABAS, A. R. (2007). Structural studies of fatty acyl-(acyl carrier protein) thioesters reveal a hydrophobic binding cavity that can expand to fit longer substrates. Journal of Molecular Biology 365, 135-145. (Pubitemid 44830032)
-
(2007)
Journal of Molecular Biology
, vol.365
, Issue.1
, pp. 135-145
-
-
Roujeinikova, A.1
Simon, W.J.2
Gilroy, J.3
Rice, D.W.4
Rafferty, J.B.5
Slabas, A.R.6
-
114
-
-
41649110512
-
Crystal structure of enoyl-acyl carrier protein reductase (FabK) from Streptococcus pneumoniae reveals the binding mode of an inhibitor
-
DOI 10.1110/ps.073288808
-
SAITO, J., YAMADA, M., WATANABE, T., IIDA, M., KITAGAWA, H., TAKAHATA, S., OZAWA, T., TAKEUCHI, Y. & OHSAWA, F. (2008). Crystal structure of enoyl-acyl carrier protein reductase (FabK) from Streptococcus pneumoniae reveals the binding mode of an inhibitor. Protein Science 17, 691-699. (Pubitemid 351480863)
-
(2008)
Protein Science
, vol.17
, Issue.4
, pp. 691-699
-
-
Saito, J.1
Yamada, M.2
Watanabe, T.3
Iida, M.4
Kitagawa, H.5
Takahata, S.6
Ozawa, T.7
Takeuchi, Y.8
Ohsawa, F.9
-
115
-
-
0017717295
-
The palmityl binding sites of fatty acid synthetase from yeast
-
SCHRECKENBACH, T., WOBSER, H. & LYNEN, F. (1977). Palmityl binding-sites of fatty-acid synthetase from yeast. European Journal of Biochemistry 80, 13-23. (Pubitemid 8213008)
-
(1977)
European Journal of Biochemistry
, vol.80
, Issue.1
, pp. 13-23
-
-
Schreckenbach, T.1
Wobser, H.2
Lynen, F.3
-
116
-
-
0028914607
-
Substrate and product binding sites of yeast fatty acid synthase. Stoichiometry and binding kinetics of wild-type and in vitro mutated enzymes
-
SCHUSTER, H., RAUTENSTRAUSS, B., MITTAG, M., STRATMANN, D. & SCHWEIZER, E. (1995). Substrate and product binding sites of yeast fatty acid synthase. Stoichiometry and binding kinetics of wild-type and in vitro mutated enzymes. European Journal of Biochemistry 228, 417-424.
-
(1995)
European Journal of Biochemistry
, vol.228
, pp. 417-424
-
-
Schuster, H.1
Rautenstrauss, B.2
Mittag, M.3
Stratmann, D.4
Schweizer, E.5
-
117
-
-
4544275674
-
Microbial type I fatty acid synthases (FAS): Major players in a network of cellular FAS systems
-
DOI 10.1128/MMBR.68.3.501-517.2004
-
SCHWEIZER, E. & HOFMANN, J. (2004). Microbial type I fatty acid synthases (FAS): major players in a network of cellular FAS systems. Microbiology and Molecular Biology Reviews 68, 501-517. (Pubitemid 39238280)
-
(2004)
Microbiology and Molecular Biology Reviews
, vol.68
, Issue.3
, pp. 501-517
-
-
Schweizer, E.1
Hofmann, J.2
-
118
-
-
0015713331
-
Pantetheine-free mutants of the yeast fatty-acid-synthetase complex
-
SCHWEIZER, E., KNIEP, B., CASTORPH, H. & HOLZNER, U. (1973). Pantetheine-free mutants of the yeast fatty-acid-synthetase complex. European Journal of Biochemistry 39, 353-362.
-
(1973)
European Journal of Biochemistry
, vol.39
, pp. 353-362
-
-
Schweizer, E.1
Kniep, B.2
Castorph, H.3
Holzner, U.4
-
119
-
-
0014850677
-
Fatty acyl transferase. Characterization of the enzyme as part of the yeast fatty acid synthetase complex by the use of radioactively labeled coenzyme A
-
SCHWEIZER, E., LERCH, I., KROEPLIN-RUEFF, L. & LYNEN, F. (1970). Fatty acyl transferase. Characterization of the enzyme as part of the yeast fatty acid synthetase complex by the use of radioactively labeled coenzyme A. European Journal of Biochemistry 15, 472-482.
-
(1970)
European Journal of Biochemistry
, vol.15
, pp. 472-482
-
-
Schweizer, E.1
Lerch, I.2
Kroeplin-Rueff, L.3
Lynen, F.4
-
120
-
-
0022636641
-
The pentafunctional FAS1 gene of yeast: Its nucleotide sequence and order of the catalytic domains
-
SCHWEIZER, M., ROBERTS, L.M., HOLTKE, H.J., TAKABAYASHI, K., HOLLERER, E., HOFFMANN, B., MULLER, G., KOTTIG, H. & SCHWEIZER, E. (1986). The pentafunctional FAS1 gene of yeast: its nucleotide sequence and order of the catalytic domains. Molecular and General Genetics 203, 479-486. (Pubitemid 16093834)
-
(1986)
Molecular and General Genetics
, vol.203
, Issue.3
, pp. 479-486
-
-
Schweizer, M.1
Roberts, L.M.2
Holtke, H.J.3
-
121
-
-
37549039510
-
A short history of SHELX. Acta Crystallographica. Section A
-
SHELDRICK, G. M. (2008). A short history of SHELX. Acta Crystallographica. Section A, Foundations of Crystallography 64, 112-122.
-
(2008)
Foundations of Crystallography
, vol.64
, pp. 112-122
-
-
Sheldrick, G.M.1
-
122
-
-
0037816242
-
Crystal structures of the quinone oxidoreductase from Thermus thermophilus HB8 and its complex with NADPH: Implication for NADPH and substrate recognition
-
DOI 10.1128/JB.185.14.4211-4218.2003
-
SHIMOMURA, Y., KAKUTA, Y. & FUKUYAMA, K. (2003). Crystal structures of the quinone oxidoreductase from Thermus thermophilus HB8 and its complex with NADPH: implication for NADPH and substrate recognition. Journal of Bacteriology 185, 4211-4218. (Pubitemid 36835261)
-
(2003)
Journal of Bacteriology
, vol.185
, Issue.14
, pp. 4211-4218
-
-
Shimomura, Y.1
Kakuta, Y.2
Fukuyama, K.3
-
123
-
-
0021343375
-
On the question of half- or full-site reactivity of animal fatty acid synthetase
-
SINGH, N., WAKIL, S. J. & STOOPS, J. K. (1984). On the question of half- or full-site reactivity of animal fatty acid synthetase. Journal of Biological Chemistry 259, 3605-3611. (Pubitemid 14173393)
-
(1984)
Journal of Biological Chemistry
, vol.259
, Issue.6
, pp. 3605-3611
-
-
Singh, N.1
Wakil, S.J.2
Stoops, J.K.3
-
124
-
-
0016410115
-
Fatty acid synthase from lactating rat mammary gland
-
SMITH, S. & ABRAHAM, S. (1975). Fatty acid synthase from lactating rat mammary gland. Methods in Enzymology 35, 65-74.
-
(1975)
Methods in Enzymology
, vol.35
, pp. 65-74
-
-
Smith, S.1
Abraham, S.2
-
125
-
-
0018792555
-
Subunit structure of the mammalian fatty-acid synthetase - Further evidence for a homodimer
-
SMITH, S. & STERN, A. (1979). Subunit structure of the mammalian fatty-acid synthetase - further evidence for a homodimer. Archives of Biochemistry and Biophysics 197, 379-387.
-
(1979)
Archives of Biochemistry and Biophysics
, vol.197
, pp. 379-387
-
-
Smith, S.1
Stern, A.2
-
126
-
-
0022408778
-
Mammalian fatty acid synthetase is a structurally and functionally symmetrical dimer
-
DOI 10.1111/j.1432-1033.1985.tb09230.x
-
SMITH, S., STERN, A., RANDHAWA, Z.I. & KNUDSEN, J. (1985). Mammalian fatty-acid synthetase is a structurally and functionally symmetrical dimer. European Journal of Biochemistry 152, 547-555. (Pubitemid 16192359)
-
(1985)
European Journal of Biochemistry
, vol.152
, Issue.3
, pp. 547-555
-
-
Smith, S.1
Stern, A.2
Randhawa, Z.I.3
Knudsen, J.4
-
127
-
-
34848843433
-
The type I fatty acid and polyketide synthases: A tale of two megasynthases
-
DOI 10.1039/b603600g
-
SMITH, S. & TSAI, S. C. (2007). The type I fatty acid and polyketide synthases: a tale of two megasynthases. Natural Product Reports 24, 1041-1072. (Pubitemid 47493392)
-
(2007)
Natural Product Reports
, vol.24
, Issue.5
, pp. 1041-1072
-
-
Smith, S.1
Tsai, S.-C.2
-
128
-
-
0037411269
-
Structural and functional organization of the animal fatty acid synthase
-
DOI 10.1016/S0163-7827(02)00067-X
-
SMITH, S., WITKOWSKI, A. & JOSHI, A. K. (2003). Structural and functional organization of the animal fatty acid synthase. Progress in Lipid Research 42, 289-317. (Pubitemid 36411688)
-
(2003)
Progress in Lipid Research
, vol.42
, Issue.4
, pp. 289-317
-
-
Smith, S.1
Witkowski, A.2
Joshi, A.K.3
-
129
-
-
0017829053
-
Further evidence for the multifunctional enzyme characteristic of the fatty acid synthetases of animal tissues. Physicochemical studies of the chicken liver fatty acid synthetase
-
STOOPS, J. K., ARSLANIAN, M. J., AUNE, K. C & WAKIL, S. J. (1978a). Further evidence for multifunctional enzyme characteristic of fatty-acid synthetases of animal-tissues - physicochemical studies of chicken liver fatty-acid synthetase. Archives of Biochemistry and Biophysics 188, 348-359. (Pubitemid 8371788)
-
(1978)
Archives of Biochemistry and Biophysics
, vol.188
, Issue.2
, pp. 348-359
-
-
Stoops, J.K.1
Arslanian, M.J.2
Aune, K.C.3
Wakil, S.J.4
-
130
-
-
0016792915
-
Presence of 2 polypeptide-chains comprising fatty-acid synthetase
-
STOOPS, J. K., ARSLANIAN, M. J., OH, Y. H., AUNE, K. C., VANAMAN, T. C. & WAKIL, S.J. (1975). Presence of 2 polypeptide-chains comprising fatty-acid synthetase. Proceedings of the National Academy of Sciences of the United States of America 72, 1940-1944.
-
(1975)
Proceedings of the National Academy of Sciences of the United States of America
, vol.72
, pp. 1940-1944
-
-
Stoops, J.K.1
Arslanian, M.J.2
H, O.H.Y.3
Aune, K.C.4
Vanaman, T.C.5
Wakil, S.J.6
-
131
-
-
0017841966
-
Studies on the yeast fatty acid synthetase. Subunit composition and structural organization of a large multifunctional enzyme complex
-
STOOPS, J. K., AWAD, E. S., ARSLANIAN, M. J., GUNSBERG, S., WAKIL, S.J. & OLIVER, R. M. (1978b). Studies on yeast fatty-acid synthetase - subunit composition and structural organization of a large multifunctional enzyme complex. Journal of Biological Chemisty 253, 4464-4475. (Pubitemid 8384143)
-
(1978)
Journal of Biological Chemistry
, vol.253
, Issue.12
, pp. 4464-4475
-
-
Stoops, J.K.1
Awad, E.S.2
Arslanian, M.J.3
-
132
-
-
0026628860
-
Structure-function relationships of the yeast fatty acid synthase: Negative-stain, cryo-electron microscopy, and image analysis studies of the end views of the structure
-
STOOPS, J. K., KOLODZIEJ, S. J., SCHROETER, J. P., BRETAUDIERE, J. P. & WAKIL, S.J. (1992). Structure-function relationships of the yeast fatty acid synthase: negative-stain, cryo-electron microscopy, and image analysis studies of the end views of the structure. Proceedings of the National Academy of Sciences of the United States of America 89, 6585-6589.
-
(1992)
Proceedings of the National Academy of Sciences of the United States of America
, vol.89
, pp. 6585-6589
-
-
Stoops, J.K.1
Kolodziej, S.J.2
Schroeter, J.P.3
Bretaudiere, J.P.4
Wakil, S.J.5
-
135
-
-
0023664701
-
Small-angle neutron-scattering and electron microscope studies of the chicken liver fatty acid synthase
-
STOOPS, J. K., WAKIL, S. J., UBERBACHER, E. C. & BUNICK, G.J. (1987). Small-angle neutron-scattering and electron microscope studies of the chicken liver fatty acid synthase. Journal of Biological Chemistry 262, 10246-10251.
-
(1987)
Journal of Biological Chemistry
, vol.262
, pp. 10246-10251
-
-
Stoops, J.K.1
Wakil, S.J.2
Uberbacher, E.C.3
Bunick, G.J.4
-
136
-
-
0014578732
-
Synthesis of various carboxylic acids by the fatty acid synthetase multienzyme complex of yeast and the explanation for their structure
-
SUMPER, M., OESTERHELT, D., RIEPERTINGER, C & LYNEN, F. (1969). Synthesis of various carboxylic acids by the fatty acid synthetase multienzyme complex of yeast and the explanation for their structure. European Journal of Biochemistry 10, 377-387.
-
(1969)
European Journal of Biochemistry
, vol.10
, pp. 377-387
-
-
Sumper, M.1
Oesterhelt, D.2
Riepertinger, C.3
Lynen, F.4
-
137
-
-
34447516335
-
Structural and Mechanistic Analysis of Protein Interactions in Module 3 of the 6-Deoxyerythronolide B Synthase
-
DOI 10.1016/j.chembiol.2007.07.012, PII S1074552107002530
-
TANG, Y., CHEN, A. Y., KIM, C. Y., CANE, D. E. & KHOSLA, C. (2007). Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase. Chemisty and Biology 14, 931-943. (Pubitemid 47268782)
-
(2007)
Chemistry and Biology
, vol.14
, Issue.8
, pp. 931-943
-
-
Tang, Y.1
Chen, A.Y.2
Kim, C.-Y.3
Cane, D.E.4
Khosla, C.5
-
138
-
-
33746776204
-
The 2.7-A crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase
-
DOI 10.1073/pnas.0601924103
-
TANG, Y., KIM, C. Y, MATHEWS, II, CANE, D. E. & KHOSLA, C. (2006). The 2-7-angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase. Proceedings of the National Academy of Sciences of the United States of America 103, 11124-11129. (Pubitemid 44159927)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.30
, pp. 11124-11129
-
-
Tang, Y.1
Kim, C.-Y.2
Mathews, I.I.3
Cane, D.E.4
Khosla, C.5
-
139
-
-
0019787336
-
Purification and properties of fatty acid synthetase from a human breast cell line
-
THOMPSON, B. J., STERN, A. & SMITH, S. (1981). Purification and properties of fatty acid synthetase from a human breast cell line. Biochimica et Biophysica Acta 662, 125-130. (Pubitemid 12216173)
-
(1981)
Biochimica et Biophysica Acta
, vol.662
, Issue.1
, pp. 125-130
-
-
Thompson, B.J.1
Stern, A.2
Smith, S.3
-
140
-
-
0021112906
-
The architecture of the animal fatty acid syn-thetase complex. IV. Mapping of active centers and model for the mechanism of action
-
TSUKAMOTO, Y., WONG, H., MATTICK, J. S. & WAKIL, S. J. (1983). The architecture of the animal fatty acid syn-thetase complex. IV. Mapping of active centers and model for the mechanism of action. Journal of Biological Chemistry 258, 15312-15322.
-
(1983)
Journal of Biological Chemistry
, vol.258
, pp. 15312-15322
-
-
Tsukamoto, Y.1
Wong, H.2
Mattick, J.S.3
Wakil, S.J.4
-
141
-
-
0017836709
-
Fatty acid synthetase assay employing bicyclic diones as substrates
-
ULLMAN, A. H., HARDING, JR., J. W. & WHITE, III, H. B. (1978). Fatty acid synthetase assay employing bicyclic diones as substrates. Analytical Biochemistry 84, 85-96. (Pubitemid 8275955)
-
(1978)
Analytical Biochemistry
, vol.84
, Issue.1
, pp. 85-96
-
-
Ullman, A.H.1
Harding Jr., J.W.2
White III, H.B.3
-
142
-
-
0015551373
-
Saturated fatty-acid biosynthesis and its regulation
-
VOLPE, J. J. & VAGELOS, P. R. (1973). Saturated fatty-acid biosynthesis and its regulation. Annual Review of Biochemistry 42, 21-60.
-
(1973)
Annual Review of Biochemistry
, vol.42
, pp. 21-60
-
-
Volpe, J.J.1
Vagelos, P.R.2
-
143
-
-
0012777853
-
A malonic acid derivative as an intermediate in fatty acid synthesis
-
American Chemical Society
-
WAKIL, S. J. (1958). A malonic acid derivative as an intermediate in fatty acid synthesis. Journal of the American Chemical Society 80, 6465-6465.
-
(1958)
Journal of the
, vol.80
, pp. 6465-6465
-
-
Wakil, S.J.1
-
144
-
-
0037965730
-
Mechanism of fatty acid synthesis
-
WAKIL, S. J. (1961). Mechanism of fatty acid synthesis. Journal of Lipid Research 2, 1-24.
-
(1961)
Journal of Lipid Research
, vol.2
, pp. 1-24
-
-
Wakil, S.J.1
-
146
-
-
0012883176
-
Mechanism of fatty acid synthesis
-
WAKIL, S. J., SAUER, F. & PUGH, E. L. (1964). Mechanism of fatty acid synthesis. Proceedings of the National Academy of Sciences of the United States of America 52, 106-114.
-
(1964)
Proceedings of the National Academy of Sciences of the United States of America
, vol.52
, pp. 106-114
-
-
Wakil, S.J.1
Sauer, F.2
Pugh, E.L.3
-
147
-
-
0033592365
-
Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) re-ductase by triclosan
-
WARD, W. H., HOLDGATE, G. A., ROWSELL, S., MCLEAN, E. G., PAUPTIT, R. A., CLAYTON, E., NICHOLS, W. W., COLLS, J. G., MINSHULL, C. A., JUDE, D. A., MISTRY, A., TIMMS, D., CAMBLE, R., HALES, N. J., BRITTON, C. J. & TAYLOR, I. W. (1999). Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) re-ductase by triclosan. Biochemistry 38, 12514-12525.
-
(1999)
Biochemistry
, vol.38
, pp. 12514-12525
-
-
Ward, W.H.1
Holdgate, G.A.2
Rowsell, S.3
McLean, E.G.4
Pauptit, R.A.5
Clayton, E.6
Nichols, W.W.7
Colls, J.G.8
Minshull, C.A.9
Jude, D.A.10
Mistry, A.11
Timms, D.12
Camble, R.13
Hales, N.J.14
Britton, C.J.15
Taylor, I.W.16
-
148
-
-
0022786302
-
Fatty-acid biosynthesis in man, a pathway of minor importance, Purification, optimal assay conditions, and organ distribution of fatty-acid synthase
-
WEISS, L., HOFFMANN, G. E., SCHREIBER, R., ANDRES, H., FUCHS, E., KORBER, E. & KOLB, H. J. (1986). Fatty-acid biosynthesis in man, a pathway of minor importance. Purification, optimal assay conditions, and organ distribution of fatty-acid synthase. Biological Chemistry Hoppe-Seyler 367, 905-912.
-
(1986)
Biological Chemistry Hoppe-Seyler
, vol.367
, pp. 905-912
-
-
Weiss, L.1
Hoffmann, G.E.2
Schreiber, R.3
Andres, H.4
Fuchs, E.5
Korber, E.6
Kolb, H.J.7
-
149
-
-
22244466130
-
The structural biology of type II fatty acid biosynthesis
-
DOI 10.1146/annurev.biochem.74.082803.133524
-
WHITE, S. W., ZHENG, J., ZHANG, Y. M. & ROCK, C. O. (2005). The structural biology of type II fatty acid biosynthesis. Annual Review of Biochemistry 74, 791-831. (Pubitemid 40995524)
-
(2005)
Annual Review of Biochemistry
, vol.74
, pp. 791-831
-
-
White, S.W.1
Zheng, J.2
Zhang, Y.-M.3
Rock, C.O.4
-
150
-
-
0018247572
-
Distribution of yeast fatty acid synthetase subunits: Three-dimensional model of the enzyme
-
WIELAND, F., SIESS, E. A., RENNER, L., VERFURTH, C. & LYNEN, F. (1978). Distribution of yeast fatty acid syn-thetase subunits: three-dimensional model of the enzyme. Proceedings of the National Academy of Sciences of the United States of America 75, 5792-5796. (Pubitemid 9099012)
-
(1978)
Proceedings of the National Academy of Sciences of the United States of America
, vol.75
, Issue.12
, pp. 5792-5796
-
-
Wieland, F.1
Siess, E.A.2
Renner, L.3
-
151
-
-
0014498927
-
Isolation of an acyl carrier protein component from multienzyme complex of yeast fatty acid synthetase
-
WILLECKE, K., RITTER, E. & LYNEN, F. (1969). Isolation of an acyl carrier protein component from multienzyme complex of yeast fatty acid synthetase. European Journal of Biochemistry 8, 503-509.
-
(1969)
European Journal of Biochemistry
, vol.8
, pp. 503-509
-
-
Willecke, K.1
Ritter, E.2
Lynen, F.3
-
152
-
-
10644281452
-
Head-to-head coiled arrangement of the subunits of the animal fatty acid synthase
-
DOI 10.1016/j.chembiol.2004.09.016, PII S1074552104003035
-
WITKOWSKI, A., GHOSAL, A., JOSHI, A.K., WITKOWSKA, H. E., ASTURIAS, F. J. & SMITH, S. (2004). Head-to-head coiled arrangement of the subunits of the animal fatty acid synthase. Chemistry and Biology 11, 1667-1676. (Pubitemid 39651301)
-
(2004)
Chemistry and Biology
, vol.11
, Issue.12
, pp. 1667-1676
-
-
Witkowski, A.1
Ghosal, A.2
Joshi, A.K.3
Witkowska, H.E.4
Asturias, F.J.5
Smith, S.6
-
153
-
-
0029816829
-
Fatty acid synthase: In vitro complementation of inactive mutants
-
DOI 10.1021/bi960910m
-
WITKOWSKI, A., JOSHI, A. & SMITH, S. (1996). Fatty acid synthase: in vitro complementation of inactive mutants. Biochemistry 35, 10569-10575. (Pubitemid 26277316)
-
(1996)
Biochemistry
, vol.35
, Issue.32
, pp. 10569-10575
-
-
Witkowski, A.1
Joshi, A.2
Smith, S.3
-
154
-
-
0025847422
-
Structural organization of the multifunctional animal fatty-acid synthase
-
WITKOWSKI, A., RANGAN, V. S., RANDHAWA, Z. I., AMY, C. M. & SMITH, S. (1991). Structural organization of the multifunctional animal fatty-acid synthase. European Journal of Biochemistry 198, 571-579.
-
(1991)
European Journal of Biochemistry
, vol.198
, pp. 571-579
-
-
Witkowski, A.1
Rangan, V.S.2
Randhawa, Z.I.3
Amy, C.M.4
Smith, S.5
-
155
-
-
0032521312
-
Genetic organization and function of the aflatoxin B1 biosynthetic genes
-
DOI 10.1016/S0378-1097(97)00588-0, PII S0378109797005880
-
WOLOSHUK, C. P. & PRIETO, R. (1998). Genetic organization and function of the aflatoxin B1 biosynthetic genes. FEMS Microbiology Letters 160, 169-176. (Pubitemid 28129298)
-
(1998)
FEMS Microbiology Letters
, vol.160
, Issue.2
, pp. 169-176
-
-
Woloshuk, C.P.1
Prieto, R.2
-
156
-
-
37349121808
-
From electron microscopy to X-ray crystallography: Molecular-replacement case studies
-
DOI 10.1107/S090744490705398X, PII S090744490705398X
-
XIONG, Y. (2008). From electron microscopy to X-ray crystallography: molecular-replacement case studies. Acta Crystallographica. Section D, Biological Crystallography 64, 76-82. (Pubitemid 350308680)
-
(2007)
Acta Crystallographica Section D: Biological Crystallography
, vol.64
, Issue.1
, pp. 76-82
-
-
Xiong, Y.1
-
157
-
-
0035896547
-
Identification and analysis of the acyl carrier protein (ACP) docking site on beta-ketoacyl-ACP synthase III
-
ZHANG, Y. M., RAO, M. S., HEATH, R. J., PRICE, A. C., OLSON, A. J., ROCK, C. O. & WHITE, S. W. (2001). Identification and analysis of the acyl carrier protein (ACP) docking site on beta-ketoacyl-ACP synthase III. Journal of Biological Chemistry 276, 8231-8238.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 8231-8238
-
-
Zhang, Y.M.1
Rao, M.S.2
Heath, R.J.3
Price, A.C.4
Olson, A.J.5
Rock, C.O.6
White, S.W.7
-
158
-
-
0346101746
-
Key Residues Responsible for Acyl Carrier Protein and β-Ketoacyl-Acyl Carrier Protein Reductase (FabG) Interaction
-
DOI 10.1074/jbc.M309874200
-
ZHANG, Y. M., WU, B., ZHENG, J. & ROCK, C. O. (2003). Key residues responsible for acyl carrier protein and beta-ketoacyl-acyl carrier protein reductase (FabG) interaction. Journal of Biological Chemistry 278, 52935-52943. (Pubitemid 38035895)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.52
, pp. 52935-52943
-
-
Zhang, Y.-M.1
Wu, B.2
Zheng, J.3
Rock, C.O.4
-
159
-
-
33645968397
-
Solution structures of spinach acyl carrier protein with decanoate and stearate
-
ZORNETZER, G. A., FOX, B. G. & MARKLEY, J. L. (2006). Solution structures of spinach acyl carrier protein with decanoate and stearate. Biochemistry 45, 5217-5227.
-
(2006)
Biochemistry
, vol.45
, pp. 5217-5227
-
-
Zornetzer, G.A.1
Fox, B.G.2
Markley, J.L.3
|