-
3
-
-
0037931325
-
Characterization of a monomeric E. coli alkaline phosphatase formed upon a single amino acid substitution
-
Boulanger R.R., and Kantrowitz E.R. Characterization of a monomeric E. coli alkaline phosphatase formed upon a single amino acid substitution. J. Biol. Chem. 278 (2003) 23497-23501
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 23497-23501
-
-
Boulanger, R.R.1
Kantrowitz, E.R.2
-
4
-
-
0029905023
-
Aspergillus has distinct fatty acid synthases for primary and secondary metabolism
-
Brown D.W., Adams T.H., and Keller N.P. Aspergillus has distinct fatty acid synthases for primary and secondary metabolism. Proc. Natl. Acad. Sci. USA 93 (1996) 14873-14877
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14873-14877
-
-
Brown, D.W.1
Adams, T.H.2
Keller, N.P.3
-
5
-
-
36049041632
-
Mechanism and substrate recognition of human holo ACP synthase
-
Bunkoczi G., Pasta S., Joshi A., Wu X., Kavanagh K.L., Smith S., and Oppermann U. Mechanism and substrate recognition of human holo ACP synthase. Chem. Biol. 14 (2007) 1243-1253
-
(2007)
Chem. Biol.
, vol.14
, pp. 1243-1253
-
-
Bunkoczi, G.1
Pasta, S.2
Joshi, A.3
Wu, X.4
Kavanagh, K.L.5
Smith, S.6
Oppermann, U.7
-
6
-
-
8144227950
-
Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain
-
Chakravarty B., Gu Z., Chirala S.S., Wakil S.J., and Quiocho F.A. Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain. Proc. Natl. Acad. Sci. USA 101 (2004) 15567-15572
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15567-15572
-
-
Chakravarty, B.1
Gu, Z.2
Chirala, S.S.3
Wakil, S.J.4
Quiocho, F.A.5
-
7
-
-
0034675957
-
Crystal structure of Streptococcus pneumoniae acyl carrier protein synthase: an essential enzyme in bacterial fatty acid biosynthesis
-
Chirgadze N.Y., Briggs S.L., McAllister K.A., Fischl A.S., and Zhao G. Crystal structure of Streptococcus pneumoniae acyl carrier protein synthase: an essential enzyme in bacterial fatty acid biosynthesis. EMBO J. 19 (2000) 5281-5287
-
(2000)
EMBO J.
, vol.19
, pp. 5281-5287
-
-
Chirgadze, N.Y.1
Briggs, S.L.2
McAllister, K.A.3
Fischl, A.S.4
Zhao, G.5
-
8
-
-
0036006782
-
Expression, purification, crystallization and preliminary X-ray analysis of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis
-
Chopra S., Kumar Singh S., Prasad Sati S., Ranganathan A., and Sharma A. Expression, purification, crystallization and preliminary X-ray analysis of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis. Acta Crystallogr. D Biol. Crystallogr. 58 (2002) 179-181
-
(2002)
Acta Crystallogr. D Biol. Crystallogr.
, vol.58
, pp. 179-181
-
-
Chopra, S.1
Kumar Singh, S.2
Prasad Sati, S.3
Ranganathan, A.4
Sharma, A.5
-
9
-
-
33646092296
-
The phosphopantetheinyl transferase superfamily: phylogenetic analysis and functional implications in cyanobacteria
-
Copp J.N., and Neilan B.A. The phosphopantetheinyl transferase superfamily: phylogenetic analysis and functional implications in cyanobacteria. Appl. Environ. Microbiol. 72 (2006) 2298-2305
-
(2006)
Appl. Environ. Microbiol.
, vol.72
, pp. 2298-2305
-
-
Copp, J.N.1
Neilan, B.A.2
-
10
-
-
48649095210
-
Acyl-carrier protein-phosphopantetheinyltransferase partnerships in fungal fatty acid synthases
-
Crawford J.M., Vagstad A.L., Ehrlich K.C., Udwary D.W., and Townsend C.A. Acyl-carrier protein-phosphopantetheinyltransferase partnerships in fungal fatty acid synthases. ChemBioChem 9 (2008) 1559-1563
-
(2008)
ChemBioChem
, vol.9
, pp. 1559-1563
-
-
Crawford, J.M.1
Vagstad, A.L.2
Ehrlich, K.C.3
Udwary, D.W.4
Townsend, C.A.5
-
11
-
-
42049099494
-
Deconstruction of iterative multidomain polyketide synthase function
-
Crawford J.M., Thomas P.M., Scheerer J.R., Vagstad A.L., Kelleher N.L., and Townsend C.A. Deconstruction of iterative multidomain polyketide synthase function. Science 320 (2008) 243-246
-
(2008)
Science
, vol.320
, pp. 243-246
-
-
Crawford, J.M.1
Thomas, P.M.2
Scheerer, J.R.3
Vagstad, A.L.4
Kelleher, N.L.5
Townsend, C.A.6
-
12
-
-
0033545834
-
Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-Aminoadipate Reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5
-
Ehmann D.E., Gehring A.M., and Walsh C.T. Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-Aminoadipate Reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5. Biochemistry 38 (1999) 6171-6177
-
(1999)
Biochemistry
, vol.38
, pp. 6171-6177
-
-
Ehmann, D.E.1
Gehring, A.M.2
Walsh, C.T.3
-
13
-
-
0014409414
-
Acyl carrier protein. X. Acyl carrier protein synthetase
-
Elovson J., and Vagelos P.R. Acyl carrier protein. X. Acyl carrier protein synthetase. J. Biol. Chem. 243 (1968) 3603-3611
-
(1968)
J. Biol. Chem.
, vol.243
, pp. 3603-3611
-
-
Elovson, J.1
Vagelos, P.R.2
-
15
-
-
0034111426
-
A novel function of yeast fatty acid synthase. Subunit alpha is capable of self-pantetheinylation
-
Fichtlscherer F., Wellein C., Mittag M., and Schweizer E. A novel function of yeast fatty acid synthase. Subunit alpha is capable of self-pantetheinylation. Eur. J. Biochem. 267 (2000) 2666-2671
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 2666-2671
-
-
Fichtlscherer, F.1
Wellein, C.2
Mittag, M.3
Schweizer, E.4
-
16
-
-
34247383568
-
Structure of fungal fatty acid synthase and implications for iterative substrate shuttling
-
Jenni S., Leibundgut M., Boehringer D., Frick C., Mikolasek B., and Ban N. Structure of fungal fatty acid synthase and implications for iterative substrate shuttling. Science 316 (2007) 254-261
-
(2007)
Science
, vol.316
, pp. 254-261
-
-
Jenni, S.1
Leibundgut, M.2
Boehringer, D.3
Frick, C.4
Mikolasek, B.5
Ban, N.6
-
17
-
-
51349099946
-
Inhibition of the fungal fatty acid synthase type I multienzyme complex
-
Johansson P., Wiltschi B., Kumari P., Kessler B., Vonrhein C., Vonck J., Oesterhelt D., and Grininger M. Inhibition of the fungal fatty acid synthase type I multienzyme complex. Proc. Natl. Acad. Sci. USA 105 (2008) 12803-12808
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 12803-12808
-
-
Johansson, P.1
Wiltschi, B.2
Kumari, P.3
Kessler, B.4
Vonrhein, C.5
Vonck, J.6
Oesterhelt, D.7
Grininger, M.8
-
18
-
-
84889120137
-
Improved methods for building protein models in electron density maps and the location of errors in these model
-
Jones T.A., Zou J.Y., Cowan S.W., and Kjeldgaard M. Improved methods for building protein models in electron density maps and the location of errors in these model. Acta Crystallogr. A. 47 (1991) 110-119
-
(1991)
Acta Crystallogr. A.
, vol.47
, pp. 110-119
-
-
Jones, T.A.1
Zou, J.Y.2
Cowan, S.W.3
Kjeldgaard, M.4
-
19
-
-
0042858246
-
Cloning, expression, and characterization of a human 4′-phosphopantetheinyl transferase with broad substrate specificity
-
Joshi A.K., Zhang L., Rangan V.S., and Smith S. Cloning, expression, and characterization of a human 4′-phosphopantetheinyl transferase with broad substrate specificity. J. Biol. Chem. 278 (2003) 33142-33149
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33142-33149
-
-
Joshi, A.K.1
Zhang, L.2
Rangan, V.S.3
Smith, S.4
-
20
-
-
0037121453
-
Identification of a key residue in the conformational stability of acyl carrier protein
-
Keating M.-M., Gong H., and Byers D.M. Identification of a key residue in the conformational stability of acyl carrier protein. Biochim. Biophys. Acta. 1601 (2002) 208-214
-
(2002)
Biochim. Biophys. Acta.
, vol.1601
, pp. 208-214
-
-
Keating, M.-M.1
Gong, H.2
Byers, D.M.3
-
21
-
-
0002906346
-
Around O
-
Rossmann M.G., and Arnold E.V. (Eds), Kluwer Academic Publishers, Dordrecht, The Netherlands
-
Kleywegt G.J., Zou J.Y., Kjeldgaard M., and Jones T.A. Around O. In: Rossmann M.G., and Arnold E.V. (Eds). International Tables for Crystallography, Vol. F. Crystallography of Biological Macromolecules (2001), Kluwer Academic Publishers, Dordrecht, The Netherlands 353-356
-
(2001)
International Tables for Crystallography, Vol. F. Crystallography of Biological Macromolecules
, pp. 353-356
-
-
Kleywegt, G.J.1
Zou, J.Y.2
Kjeldgaard, M.3
Jones, T.A.4
-
22
-
-
0029904850
-
Structure-function relationships of the Saccharomyces cerevisiae fatty acid synthase. Three-dimensional structure
-
Kolodziej S.J., Penczek P.A., Schroeter J.P., and Stoops J.K. Structure-function relationships of the Saccharomyces cerevisiae fatty acid synthase. Three-dimensional structure. J. Biol. Chem. 271 (1996) 28422-28429
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 28422-28429
-
-
Kolodziej, S.J.1
Penczek, P.A.2
Schroeter, J.P.3
Stoops, J.K.4
-
23
-
-
0028882690
-
Cloning, overproduction, and characterization of the Escherichia coli holo-acyl carrier protein synthase
-
Lambalot R.H., and Walsh C.T. Cloning, overproduction, and characterization of the Escherichia coli holo-acyl carrier protein synthase. J. Biol. Chem. 270 (1995) 24658-24661
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 24658-24661
-
-
Lambalot, R.H.1
Walsh, C.T.2
-
24
-
-
0030294470
-
A new enzyme superfamily-the phosphopantetheinyl transferases
-
Lambalot R.H., Gehring A.M., Flugel R.S., Zuber P., LaCelle M., Marahiel M.A., Reid R., Khosla C., and Walsh C.T. A new enzyme superfamily-the phosphopantetheinyl transferases. Chem. Biol. 3 (1996) 923-936
-
(1996)
Chem. Biol.
, vol.3
, pp. 923-936
-
-
Lambalot, R.H.1
Gehring, A.M.2
Flugel, R.S.3
Zuber, P.4
LaCelle, M.5
Marahiel, M.A.6
Reid, R.7
Khosla, C.8
Walsh, C.T.9
-
25
-
-
34247353309
-
Structural basis for substrate delivery by acyl carrier protein in the yeast fatty acid synthase
-
Leibundgut M., Jenni S., Frick C., and Ban N. Structural basis for substrate delivery by acyl carrier protein in the yeast fatty acid synthase. Science 316 (2007) 288-290
-
(2007)
Science
, vol.316
, pp. 288-290
-
-
Leibundgut, M.1
Jenni, S.2
Frick, C.3
Ban, N.4
-
26
-
-
34147098650
-
The crystal structure of yeast fatty acid synthase, a cellular machine with eight active sites working together
-
Lomakin I.B., Xiong Y., and Steitz T.A. The crystal structure of yeast fatty acid synthase, a cellular machine with eight active sites working together. Cell 129 (2007) 319-332
-
(2007)
Cell
, vol.129
, pp. 319-332
-
-
Lomakin, I.B.1
Xiong, Y.2
Steitz, T.A.3
-
27
-
-
0019164234
-
On the structure of fatty acid synthetase of yeast
-
Lynen F. On the structure of fatty acid synthetase of yeast. Eur. J. Biochem. 112 (1980) 431-442
-
(1980)
Eur. J. Biochem.
, vol.112
, pp. 431-442
-
-
Lynen, F.1
-
28
-
-
51149098989
-
The crystal structure of a mammalian fatty acid synthase
-
Maier T., Leibundgut M., and Ban N. The crystal structure of a mammalian fatty acid synthase. Science 321 (2008) 1315-1322
-
(2008)
Science
, vol.321
, pp. 1315-1322
-
-
Maier, T.1
Leibundgut, M.2
Ban, N.3
-
29
-
-
34447508216
-
Phaser crystallographic software
-
McCoy A.J., Grosse-Kunstleve R.W., Adams P.D., Winn M.D., Storoni L.C., and Read R.J. Phaser crystallographic software. J. Appl. Crystallogr. 40 (2007) 658-674
-
(2007)
J. Appl. Crystallogr.
, vol.40
, pp. 658-674
-
-
McCoy, A.J.1
Grosse-Kunstleve, R.W.2
Adams, P.D.3
Winn, M.D.4
Storoni, L.C.5
Read, R.J.6
-
30
-
-
0032885261
-
The x-ray crystal structure of beta-ketoacyl [acyl carrier protein] synthase I
-
Olsen J.G., Kadziola A., Von Wettstein-Knowles P., Siggaard-Andersen M., Lindquist Y., and Larsen S. The x-ray crystal structure of beta-ketoacyl [acyl carrier protein] synthase I. FEBS Lett. 460 (1999) 46-52
-
(1999)
FEBS Lett.
, vol.460
, pp. 46-52
-
-
Olsen, J.G.1
Kadziola, A.2
Von Wettstein-Knowles, P.3
Siggaard-Andersen, M.4
Lindquist, Y.5
Larsen, S.6
-
31
-
-
0034662753
-
Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites
-
Parris K.D., Lin L., Tam A., Mathew R., Hixon J., Stahl M., Fritz C.C., Seehra J., and Somers W.S. Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites. Structure 8 (2000) 883-895
-
(2000)
Structure
, vol.8
, pp. 883-895
-
-
Parris, K.D.1
Lin, L.2
Tam, A.3
Mathew, R.4
Hixon, J.5
Stahl, M.6
Fritz, C.C.7
Seehra, J.8
Somers, W.S.9
-
32
-
-
38049136859
-
A mammalian type I fatty acid synthase acyl carrier protein domain does not sequester acyl chains
-
Ploskon E., Arthur C.J., Evans S.E., Williams C., Crosby J., Simpson T.J., and Crump M.P. A mammalian type I fatty acid synthase acyl carrier protein domain does not sequester acyl chains. J. Biol. Chem. 283 (2008) 518-528
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 518-528
-
-
Ploskon, E.1
Arthur, C.J.2
Evans, S.E.3
Williams, C.4
Crosby, J.5
Simpson, T.J.6
Crump, M.P.7
-
33
-
-
0035980230
-
Structure of beta-ketoacyl-[acyl carrier protein] reductase from Escherichia coli: negative cooperativity and its structural basis
-
Price A.C., Zhang Y.M., Rock C.O., and White S.W. Structure of beta-ketoacyl-[acyl carrier protein] reductase from Escherichia coli: negative cooperativity and its structural basis. Biochemistry 40 (2001) 12772-12781
-
(2001)
Biochemistry
, vol.40
, pp. 12772-12781
-
-
Price, A.C.1
Zhang, Y.M.2
Rock, C.O.3
White, S.W.4
-
34
-
-
0035896021
-
Refined structures of beta -ketoacyl-acyl carrier protein synthase III
-
Qiu X., Janson C.A., Smith W.W., Head M., Lonsdale J., and Konstantinidis A.K. Refined structures of beta -ketoacyl-acyl carrier protein synthase III. J. Mol. Biol. 307 (2001) 341-356
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 341-356
-
-
Qiu, X.1
Janson, C.A.2
Smith, W.W.3
Head, M.4
Lonsdale, J.5
Konstantinidis, A.K.6
-
35
-
-
0033485259
-
Crystal structure of the surfactin synthetase-activating enzyme Sfp: a prototype of the 4′-phosphopantetheinyl transferase superfamily
-
Reuter K., Mofid M.R., Marahiel M.A., and Ficner R. Crystal structure of the surfactin synthetase-activating enzyme Sfp: a prototype of the 4′-phosphopantetheinyl transferase superfamily. EMBO J. 18 (1999) 6823-6831
-
(1999)
EMBO J.
, vol.18
, pp. 6823-6831
-
-
Reuter, K.1
Mofid, M.R.2
Marahiel, M.A.3
Ficner, R.4
-
36
-
-
0036277954
-
X-ray crystallographic studies on butyryl-ACP reveal flexibility of the structure around a putative acyl chain binding site
-
Roujeinikova A., Baldock C., Simon W.J., Gilroy J., Baker P.J., Stuitje A.R., Rice D.W., Slabas A.R., and Rafferty J.B. X-ray crystallographic studies on butyryl-ACP reveal flexibility of the structure around a putative acyl chain binding site. Structure 10 (2002) 825-835
-
(2002)
Structure
, vol.10
, pp. 825-835
-
-
Roujeinikova, A.1
Baldock, C.2
Simon, W.J.3
Gilroy, J.4
Baker, P.J.5
Stuitje, A.R.6
Rice, D.W.7
Slabas, A.R.8
Rafferty, J.B.9
-
37
-
-
4544275674
-
Microbial type I fatty acid synthases (FAS): major players in a network of cellular FAS systems
-
Schweizer E., and Hofmann J. Microbial type I fatty acid synthases (FAS): major players in a network of cellular FAS systems. Microbiol. Mol. Biol. Rev. 68 (2004) 501-517
-
(2004)
Microbiol. Mol. Biol. Rev.
, vol.68
, pp. 501-517
-
-
Schweizer, E.1
Hofmann, J.2
-
38
-
-
0344631518
-
Substrate channeling
-
Spivey H.O., and Ovadi J. Substrate channeling. Methods 19 (1999) 306-321
-
(1999)
Methods
, vol.19
, pp. 306-321
-
-
Spivey, H.O.1
Ovadi, J.2
-
39
-
-
33845482665
-
Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms
-
Vedadi M., Lew J., Artz J., Amani M., Zhao Y., Dong A., Wasney G.A., Gao M., Hills T., Brokx S., et al. Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol. Biochem. Parasitol. 151 (2007) 100-110
-
(2007)
Mol. Biochem. Parasitol.
, vol.151
, pp. 100-110
-
-
Vedadi, M.1
Lew, J.2
Artz, J.3
Amani, M.4
Zhao, Y.5
Dong, A.6
Wasney, G.A.7
Gao, M.8
Hills, T.9
Brokx, S.10
-
40
-
-
33744994317
-
Platensimycin is a selective FabF inhibitor with potent antibiotic properties
-
Wang J., Soisson S.M., Young K., Shoop W., Kodali S., Galgoci A., Painter R., Parthasarathy G., Tang Y.S., Cummings R., et al. Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature 441 (2006) 358-361
-
(2006)
Nature
, vol.441
, pp. 358-361
-
-
Wang, J.1
Soisson, S.M.2
Young, K.3
Shoop, W.4
Kodali, S.5
Galgoci, A.6
Painter, R.7
Parthasarathy, G.8
Tang, Y.S.9
Cummings, R.10
-
41
-
-
0036752689
-
Initial characterization of a type I fatty acid synthase and polyketide synthase multienzyme complex NorS in the biosynthesis of alfatoxin B1
-
Watanabe C.M.H., and Townsend C.A. Initial characterization of a type I fatty acid synthase and polyketide synthase multienzyme complex NorS in the biosynthesis of alfatoxin B1. Chem. Biol. 9 (2002) 981-988
-
(2002)
Chem. Biol.
, vol.9
, pp. 981-988
-
-
Watanabe, C.M.H.1
Townsend, C.A.2
-
42
-
-
0019327118
-
Coenzyme A: fatty acid synthetase apoenzyme 4′-phosphopantetheine transferase in yeast
-
Werkmeister K., Wieland F., and Schweizer E. Coenzyme A: fatty acid synthetase apoenzyme 4′-phosphopantetheine transferase in yeast. Biochem. Biophys. Res. Commun. 96 (1980) 483-490
-
(1980)
Biochem. Biophys. Res. Commun.
, vol.96
, pp. 483-490
-
-
Werkmeister, K.1
Wieland, F.2
Schweizer, E.3
-
43
-
-
0037238269
-
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase
-
Zhang Y.-M., Marrakchi H., White S.W., and Rock C.O. The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase. J. Lipid Res. 44 (2003) 1-10
-
(2003)
J. Lipid Res.
, vol.44
, pp. 1-10
-
-
Zhang, Y.-M.1
Marrakchi, H.2
White, S.W.3
Rock, C.O.4
|