Structures of β-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery

Structure

Volumn 9, Issue 3, 2001, Pages 233-243

  Olsen, Johan Gotthardt ^a   Kadziola, Anders ^a   Von Wettstein Knowles, Penny ^b   Siggaard Andersen, Mads ^b   Larsen, Sine ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Catalytic mechanism; Claisen condensation; Decarboxylation; Enzyme fatty acid complex; Fatty acid biosynthesis

Indexed keywords

3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE; ACETYL COENZYME A ACETYLTRANSFERASE; ASPARAGINE; CARBON; CHALCONE SYNTHASE; DIMER; FATTY ACID; HISTIDINE; ISOENZYME; MALONIC ACID DERIVATIVE; MEMBRANE LIPID; THIOESTER;

ARTICLE; BACTERIAL MEMBRANE; CATALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; DECARBOXYLATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME STRUCTURE; HYDROGEN BOND; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTON TRANSPORT; STRUCTURE ANALYSIS;

3-OXOACYL-(ACYL-CARRIER-PROTEIN) SYNTHASE; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DECARBOXYLATION; ESCHERICHIA COLI; FATTY ACID SYNTHETASE COMPLEX; FATTY ACIDS; ISOENZYMES; MODELS, MOLECULAR;

BACTERIA (MICROORGANISMS); NEGIBACTERIA;

EID: 0035085234     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00583-4     Document Type: Article

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