Visualizing flexibility at molecular resolution: Analysis of heterogeneity in single-particle electron microscopy reconstructions

Annual Review of Biophysics and Biomolecular Structure

Volumn 36, Issue , 2007, Pages 43-62

  Leschziner, Andres E ^a   Nogales, Eva ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

3D variance; Conformational flexibility; Cryo EM; Macromolecular assemblies; Maximum likelihood

Indexed keywords

CAMERA; CONFORMATION; CONFORMATIONAL TRANSITION; CRYOELECTRON MICROSCOPY; DIGITAL IMAGING; IMAGE ANALYSIS; IMAGE DISPLAY; IMAGE PROCESSING; IMAGE QUALITY; IMAGE RECONSTRUCTION; IMAGING SYSTEM; MACROMOLECULE; MAXIMUM LIKELIHOOD METHOD; MOLECULAR IMAGING; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; REVIEW; SINGLE PARTICLE ELECTRON MICROSCOPY; VARIANCE;

ANIMALS; BIOPHYSICS; CRYOELECTRON MICROSCOPY; ESCHERICHIA COLI; FOURIER ANALYSIS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; LIKELIHOOD FUNCTIONS; MACROMOLECULAR SUBSTANCES; MOLECULAR CONFORMATION; OSCILLOMETRY; RIBOSOMES;

EID: 34347236451     PISSN: 10568700     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.biophys.36.040306.132742     Document Type: Review

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