Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography

Acta Crystallographica Section D: Biological Crystallography

Volumn 62, Issue 6, 2006, Pages 613-618

  Oefner, Christian ^a,c   Schulz, Henk ^a,c   D'Arcy, Allan ^b   Dale, Glenn E ^a,c  

^a Morphochem AG Basel   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

^c Arpida Ltd   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CARRIER PROTEIN MALONYLTRANSFERASE; ESCHERICHIA COLI PROTEIN; FABD PROTEIN, E COLI; MALONYL COENZYME A;

ARTICLE; BINDING SITE; CATALYSIS; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; X RAY CRYSTALLOGRAPHY;

ACYL-CARRIER PROTEIN S-MALONYLTRANSFERASE; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI PROTEINS; MALONYL COENZYME A; MODELS, CHEMICAL; MODELS, MOLECULAR; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 33744460734     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444906009474     Document Type: Article

References (28)

1. Campbell, J. W. & Cronan, J. E. Jr (2001). Annu. Rev. Microbiol. 55, 305-332.
2. Clough, R. C., Matthis, A. L., Barnum, S. R. & Jaworski, J. G. (1992). J. Biol Chem. 267, 20992-20998.
3. Collaborative Computational Project, Number 4 (1994). Acta Cryst. D50, 760-763.
4. DeLano, W. L. (2001). The PyMOL User's Manual. DeLano Scientific, San Carlos, CA, USA.
5. Donadio, S., Staver, M. J., McAlpine, J. B., Swanson, S. J. & Katz, L. (1991). Science, 252, 675-679.
6. Dreier, J., Li, Q. & Koshland, C. (2001). Biochemistry, 40, 12407-12411.
7. Engh, R. & Huber, R. A. (1991). Acta Cryst. A47, 392-400.
8. Gerber, P. (1992). Biopolymers, 32, 1003-1017.
9. Heath, R. J., White, S. W. & Rock, C. O. (2002). Appl. Microbiol. Biotechnol. 58, 695-703.
10. Hol, W. (1985). Adv. Biophys. 19, 1333-165.
11. Joshi, V. C. & Wakil, S. J. (1971). Arch. Biochem. Biophys. 143, 493-505.
12. Keatinge-Clay, A. T., Shelat, A. A., Savage, D. F., Tsai, S. C., Miercke, L. J., O'Connell, J. D. III, Khosla, C. & Stroud, R. M. (2003). Structure, 11, 147-154.
13. Kraulis, P. J. (1991). J. Appl. Cryst. 24, 946-950.
14. Magnuson, K., Jackowski, S., Rock, C. O. & Cronan, J. E. Jr (1993). Microbiol Rev. 57, 522-542.
15. Merritt, E. A. & Bacon, D. J. (1997). Methods Enzymol. 277, 505-524.
16. Molnos, J., Gardiner, R., Dale, G. E. & Lange, R. (2003). Anal Biochem. 319, 171-176.
17. Murshudov, G. N., Vagin, A. A. & Dodson, E. J. (1997). Acta Cryst. D53, 240-255.
18. Otwinowski, Z. (1993). Proceedings of the CCP4 Study Weekend. Data Collection and Processing, edited by L. Sawyer, N. Isaacs & S. Bailey, pp. 56-62. Warrington: Daresbury Laboratory.
19. Price, A. C., Choi, K. H., Heath, R. J., Li, Z., White, S. W. & Rock, C. O. (2001). J. Biol. Chem. 276, 6551-6559.
20. Ruch, F. E. & Vagelos, P. R. (1973). J. Biol. Chem. 248, 8086-8094.
21. Serre, L., Swenson, L., Green, R., Wei, Y., Verwoert, I. I., Verbree, E. C., Stuitje, A. R. & Derewenda, Z. S. (1994). J. Mol. Biol. 242, 99-102.
22. Serre, L, Verbree, E. C., Dauter, Z., Stuitje, A. R. & Derewenda, Z. S. (1995). J. Biol. Chem. 270, 12961-12964.
23. Smith, S. (1994). FASEB J. 15, 1248-1259.
24. Thoden, J. B., Holden, H. M., Zhuang, Z. & Dunaway-Mariano, D. (2002). J. Biol. Chem. 277, 27468-27476.
25. Tsay, J. T., Oh, W., Larson, T. J., Jackowski, S. & Rock, C. O. (1992). J. Biol. Chem. 267, 6807-6814.
26. Verwoert, I. I., Verhagen, E. F., van der Linden, K. H., Verbree, E. C., Nijkamp, H. J. & Stuitje, A. R. (1994). FEBS Lett. 348, 311-316.
27. Waller, R. F., Keeling, P. J., Donald, R. G., Striepen, B., Handman, E., Lang-Unnasch, N., Cowman, A. F., Besra, G. S., Roos, D. S. & McFadden, G. I. (1998). Proc. Natl Acad. Sci. USA, 95, 12352-12357.
28. Zhang, Y. & Cronan, J. E. Jr (1998). J. Bacteriol. 180, 3295-3303.