Alteration of the substrate specificity of the malonyl-CoA/acetyl- CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue

Journal of Biological Chemistry

Volumn 272, Issue 18, 1997, Pages 11975-11978

  Rangan, Vangipuram S ^a   Smith, Stuart ^a  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A ACETYLTRANSFERASE; CARRIER PROTEIN; FATTY ACID SYNTHASE; GUANIDINE; MALONYL COENZYME A;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

ACETYL COENZYME A; AMINO ACID SEQUENCE; ANIMALS; ARGININE; CLONING, MOLECULAR; COENZYME A-TRANSFERASES; CONSERVED SEQUENCE; ESCHERICHIA COLI; FATTY ACID SYNTHETASE COMPLEX; KINETICS; MALONYL COENZYME A; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; RATS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 0030911617     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.18.11975     Document Type: Article

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