-
1
-
-
3242730474
-
Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans
-
DOI 10.1152/ajpendo.00545.2003
-
Holst JJ, Gromada J. Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans. Am J Physiol Endocrinol Metab 2004;287:E199-206 (Pubitemid 38943883)
-
(2004)
American Journal of Physiology - Endocrinology and Metabolism
, vol.287
, Issue.2-50
-
-
Holst, J.J.1
Gromada, J.2
-
2
-
-
0024836493
-
Glucagonostatic and insulinotropic action of glucagonlike peptide I-(7-36)-amide
-
Komatsu R, Matsuyama T, Namba M, et al. Glucagonostatic and insulinotropic action of glucagon-like peptide I-(7-36)-amide. Diabetes 1989;38:902-5 (Pubitemid 20022397)
-
(1989)
Diabetes
, vol.38
, Issue.7
, pp. 902-905
-
-
Komatsu, R.1
Matsuyama, T.2
Namba, M.3
Watanabe, N.4
Itoh, H.5
Kono, N.6
Tarui, S.7
-
3
-
-
0023758530
-
Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach
-
Orskov C, Holst JJ, Nielsen OV. Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach. Endocrinology 1988;123: 2009-13
-
(1988)
Endocrinology
, vol.123
, pp. 2009-13
-
-
Orskov, C.1
Holst, J.J.2
Nielsen, O.V.3
-
4
-
-
0023950336
-
Distribution of glucagon-like peptide i (GLP-I), glucagon, and glicentin in the rat brain: An immunocytochemical study
-
Jin SL, Han VK, Simmons JG, et al. Distribution of glucagon-like peptide I (GLP-I), glucagon, and glicentin in the rat brain: an immunocytochemical study. J Comp Neurol 1988;271:519-32
-
(1988)
J Comp Neurol
, vol.271
, pp. 519-32
-
-
Jin, S.L.1
Han, V.K.2
Simmons, J.G.3
-
5
-
-
0036307872
-
Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons
-
DOI 10.1172/JCI200215595
-
Yamamoto H, Lee CE, Marcus JN, et al. Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons. J Clin Invest 2002;110:43-52 (Pubitemid 34743464)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.1
, pp. 43-52
-
-
Yamamoto, H.1
Lee, C.E.2
Marcus, J.N.3
Williams, T.D.4
Michael Overton, J.5
Lopez, M.E.6
Hollenberg, A.N.7
Baggio, L.8
Saper, C.B.9
Drucker, D.J.10
Elmquist, J.K.11
-
6
-
-
55849125147
-
Role of central nervous system glucagon-like peptide-1 receptors in enteric glucose sensing
-
Knauf C, Cani PD, Kim DH, et al. Role of central nervous system glucagon-like peptide-1 receptors in enteric glucose sensing. Diabetes 2008;57:2603-12
-
(2008)
Diabetes
, vol.57
, pp. 2603-12
-
-
Knauf, C.1
Cani, P.D.2
Kim, D.H.3
-
7
-
-
0031029936
-
Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem
-
DOI 10.1016/S0306-4522(96)00434-4, PII S0306452296004344
-
Larsen PJ, Tang-Christensen M, Holst JJ, et al. Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem. Neuroscience 1997;77:257-70 (Pubitemid 27060323)
-
(1997)
Neuroscience
, vol.77
, Issue.1
, pp. 257-270
-
-
Larsen, P.J.1
Tang-Christensen, M.2
Holst, J.J.3
Orskov, C.4
-
8
-
-
0032923740
-
Coexpression of glucagon-like peptide-1 (GLP-1) receptor, vasopressin, and oxytocin mRNAs in neurons of the rat hypothalamic supraoptic and paraventricular nuclei: Effect of GLP-1(7-36)amide on vasopressin and oxytocin release
-
DOI 10.1046/j.1471-4159.1999.0720010.x
-
Zueco JA, Esquifino AI, Chowen JA, et al. Coexpression of glucagon-like peptide-1 (GLP-1) receptor, vasopressin, and oxytocin mRNAs in neurons of the rat hypothalamic supraoptic and paraventricular nuclei: effect of GLP-1(7-36) amide on vasopressin and oxytocin release. J Neurochem 1999;72:10-6 (Pubitemid 29013872)
-
(1999)
Journal of Neurochemistry
, vol.72
, Issue.1
, pp. 10-16
-
-
Zueco, J.A.1
Esquifino, A.I.2
Chowen, J.A.3
Alvarez, E.4
Castrillon, P.O.5
Blazquez, E.6
-
9
-
-
0029859220
-
Central administration of GLP-1-( 7-36) amide inhibits food and water intake in rats
-
Tang-Christensen M, Larsen PJ, Göke R, et al. Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats. Am J Physiol 1996;271:R848-56
-
(1996)
Am J Physiol
, vol.271
-
-
Tang-Christensen, M.1
Larsen, P.J.2
Göke, R.3
-
10
-
-
0031891391
-
PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in rats
-
McMahon LR, Wellman PJ. PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in rats. Am J Physiol 1998;274:R23-9
-
(1998)
Am J Physiol
, vol.274
-
-
McMahon, L.R.1
Wellman, P.J.2
-
11
-
-
13344282056
-
A role for glucagon-like peptide-1 in the central regulation of feeding
-
DOI 10.1038/379069a0
-
Turton MD, O'Shea D, Gunn I, et al. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 1996;379:69-72 (Pubitemid 26008136)
-
(1996)
Nature
, vol.379
, Issue.6560
, pp. 69-72
-
-
Turton, M.D.1
O'Shea, D.2
Gunn, I.3
Beak, S.A.4
Edwards, C.M.B.5
Meeran, K.6
Choi, S.J.7
Taylor, G.M.8
Heath, M.M.9
Lambert, P.D.10
Wilding, J.P.H.11
Smith, D.M.12
Ghatei, M.A.13
Herbert, J.14
Bloom, S.R.15
-
12
-
-
31044456099
-
Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage
-
DOI 10.1172/JCI25764
-
Knauf C, Cani PD, Perrin C, et al. Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage. J Clin Invest 2005;115:3554-63 (Pubitemid 43121843)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.12
, pp. 3554-3563
-
-
Knauf, C.1
Cani, P.D.2
Perrin, C.3
Iglesias, M.A.4
Maury, J.F.5
Bernard, E.6
Benhamed, F.7
Gremeaux, T.8
Drucker, D.J.9
Kahn, C.R.10
Girard, J.11
Tanti, J.F.12
Delzenne, N.M.13
Postic, C.14
Burcelin, R.15
-
13
-
-
0032005005
-
Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
-
Flint A, Raben A, Astrup A, et al. Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest 1998;101:515-20 (Pubitemid 28084232)
-
(1998)
Journal of Clinical Investigation
, vol.101
, Issue.3
, pp. 515-520
-
-
Flint, A.1
Raben, A.2
Astrup, A.3
Holst, J.J.4
-
14
-
-
57649192347
-
Brain glucagon-like peptide-1 regulates arterial blood flow, heart rate, and insulin sensitivity
-
Cabou C, Campistron G, Marsollier N, et al. Brain glucagon-like peptide-1 regulates arterial blood flow, heart rate, and insulin sensitivity. Diabetes 2008;57:2577-87
-
(2008)
Diabetes
, vol.57
, pp. 2577-87
-
-
Cabou, C.1
Campistron, G.2
Marsollier, N.3
-
15
-
-
70449709114
-
A role for the gut-to-brain GLP-1-dependent axis in the control of metabolism
-
Burcelin R, Serino M, Cabou C. A role for the gut-to-brain GLP-1-dependent axis in the control of metabolism. Curr Opin Pharmacol 2009;9:744-52
-
(2009)
Curr Opin Pharmacol
, vol.9
, pp. 744-52
-
-
Burcelin, R.1
Serino, M.2
Cabou, C.3
-
16
-
-
0029903111
-
Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I
-
Orskov C, Poulsen SS, Moller M, et al. Glucagon-like peptide 1 receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I. Diabetes 1996;45:832-5 (Pubitemid 26168585)
-
(1996)
Diabetes
, vol.45
, Issue.6
, pp. 832-835
-
-
Orskov, C.1
Poulsen, S.S.2
Moller, M.3
Holst, J.J.4
-
17
-
-
67449169287
-
Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat
-
Bucinskaite V, Tolessa T, Pedersen J, et al. Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat. Neurogastroenterol Motil 2009;21:978-e78
-
(2009)
Neurogastroenterol Motil
, vol.21
-
-
Bucinskaite, V.1
Tolessa, T.2
Pedersen, J.3
-
18
-
-
67649649953
-
Minireview: Finding the sweet spot: Peripheral versus central glucagon-like peptide 1 action in feeding and glucose homeostasis
-
Williams DL. Minireview: finding the sweet spot: peripheral versus central glucagon-like peptide 1 action in feeding and glucose homeostasis. Endocrinology 2009;150:2997-3001
-
(2009)
Endocrinology
, vol.150
, pp. 2997-3001
-
-
Williams, D.L.1
-
19
-
-
0026775150
-
Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1
-
Thorens B. Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1. Proc Natl Acad Sci USA 1992;89:8641-5
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 8641-5
-
-
Thorens, B.1
-
20
-
-
5044222306
-
Pyridoxine-induced toxicity in rats: A stereological quantification of the sensory neuropathy
-
DOI 10.1016/j.expneurol.2004.07.013, PII S0014488604002948
-
Perry TA, WeerasuriyaA, Mouton PR, etal. Pyridoxine-induced toxicity in rats: a stereological quantification of the sensory neuropathy. Exp Neurol 2004;190:133-44 (Pubitemid 39335713)
-
(2004)
Experimental Neurology
, vol.190
, Issue.1
, pp. 133-144
-
-
Perry, T.A.1
Weerasuriya, A.2
Mouton, P.R.3
Holloway, H.W.4
Greig, N.H.5
-
21
-
-
3042792777
-
2 with 2-aminobutyric acid
-
DOI 10.1016/j.abb.2004.05.005, PII S0003986104002723
-
Green B, Gault V Flatt P, etal. Comparative effects of GLP-1 and GIP on cAMP production, insulin secretion, and in vivo antidiabetic actions following substitution of Ala8/Ala2 with 2-aminobutyric acid. Arch Biochem Biophys 2004;428:136-43 (Pubitemid 38891556)
-
(2004)
Archives of Biochemistry and Biophysics
, vol.428
, Issue.2
, pp. 136-143
-
-
Green, B.D.1
Gault, V.A.2
Flatt, P.R.3
Harriott, P.4
Greer, B.5
O'Harte, F.P.M.6
-
22
-
-
0037241085
-
Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects
-
DOI 10.1210/jc.2002-021053
-
Vilsbøll T, Agersø H, Krarup T, et al. Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects. J Clin Endocrinol Metab 2003;88:220-4 (Pubitemid 36115169)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.1
, pp. 220-224
-
-
Vilsboll, T.1
Agerso, H.2
Krarup, T.3
Holst, J.J.4
-
23
-
-
43249089631
-
Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways
-
DOI 10.1161/CIRCULATIONAHA.107.739938, PII 0000301720080506000007
-
Ban K, Noyan-Ashraf MH, Hoefer J, et al. Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways. Circulation 2008;117:2340-50 (Pubitemid 351653542)
-
(2008)
Circulation
, vol.117
, Issue.18
, pp. 2340-2350
-
-
Ban, K.1
Noyan-Ashraf, M.H.2
Hoefer, J.3
Bolz, S.-S.4
Drucker, D.J.5
Husain, M.6
-
24
-
-
77950267745
-
Glucagon-like peptide (GLP)-1 ( 9-36) amide-mediated cytoprotection is blocked by exendin (9-39) yet does not require the known GLP-1 receptor
-
Ban K, Kim KH, Cho CK, et al. Glucagon-like peptide (GLP)-1 (9-36) amide-mediated cytoprotection is blocked by exendin (9-39) yet does not require the known GLP-1 receptor. Endocrinology 2010;151:1520-31
-
(2010)
Endocrinology
, vol.151
, pp. 1520-31
-
-
Ban, K.1
Kim, K.H.2
Cho, C.K.3
-
25
-
-
3442896818
-
A new Alzheimer's disease interventive strategy: GLP-1
-
DOI 10.2174/1389450043345245
-
Perry TA, Greig N. A new Alzheimer's disease interventive strategy: GLP-1 Current Drug Targets 2004;5:565-71 (Pubitemid 39004431)
-
(2004)
Current Drug Targets
, vol.5
, Issue.6
, pp. 565-571
-
-
Perry, T.A.1
Greig, N.H.2
-
26
-
-
0036721026
-
Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4
-
DOI 10.1124/jpet.102.037481
-
Perry TA, Haughey N, Mattison M, et al. Protection and reversal of excitotxic neuronal damage by glucagon-like peptide-1 and exendin 4. J Pharmacol Exp Ther 2002;302:881-8 (Pubitemid 34920207)
-
(2002)
Journal of Pharmacology and Experimental Therapeutics
, vol.302
, Issue.3
, pp. 881-888
-
-
Perry, T.1
Haughey, N.J.2
Mattson, M.P.3
Egan, J.M.4
Greig, N.H.5
-
27
-
-
10244241840
-
Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: Evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water intake
-
Navarro M, de Fonseca R, Alvarez E, et al. Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water intake. J Neurochem 1996;67:1982-91 (Pubitemid 26349672)
-
(1996)
Journal of Neurochemistry
, vol.67
, Issue.5
, pp. 1982-1991
-
-
Navarro, M.1
Rodriguez De Fonseca, F.2
Alvarez, E.3
Chowen, J.A.4
Zueco, J.A.5
Gomez, R.6
Eng, J.7
Blazquez, E.8
-
28
-
-
0028867442
-
Distribution of GLP-1 binding sites in the rat brain: Evidence that exendin-4 is a ligand of brain GLP-1 binding sites
-
Goke R, Larsen PJ, Mikkelsen JD, et al. Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites. Eur J Neurosci 1995;7:2294-300
-
(1995)
Eur J Neurosci
, vol.7
, pp. 2294-300
-
-
Goke, R.1
Larsen, P.J.2
Mikkelsen, J.D.3
-
29
-
-
34250635159
-
GLP-1 receptor expression in human tumors and human normal tissues: Potential for in vivo targeting
-
DOI 10.2967/jnumed.106.038679
-
Körner M, Stöckli M, Waser B, et al. GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting. J Nucl Med 2007;48:736-43 (Pubitemid 47604973)
-
(2007)
Journal of Nuclear Medicine
, vol.48
, Issue.5
, pp. 736-743
-
-
Korner, M.1
Stockli, M.2
Waser, B.3
Reubi, J.C.4
-
30
-
-
70449111654
-
Glucagon-like peptide-1 receptor imaging for localization of insulinomas
-
Christ E, Wild D, Forrer F, et al. Glucagon-like peptide-1 receptor imaging for localization of insulinomas. J Clin Endocrinol Metab 2009;94:4398-405
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 4398-405
-
-
Christ, E.1
Wild, D.2
Forrer, F.3
-
31
-
-
0037312818
-
Glucagon-like peptides: Regulators of cell proliferation, differentiation, and apoptosis
-
DOI 10.1210/me.2002-0306
-
Drucker DJ. Glucagon-like peptides: regulators of cell proliferation, differentiation and apoptosis. Molecular Endocrinology 2003;17:161-71 (Pubitemid 36183142)
-
(2003)
Molecular Endocrinology
, vol.17
, Issue.2
, pp. 161-171
-
-
Drucker, D.J.1
-
32
-
-
0034032317
-
Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas
-
Stoffers DA, KiefferTJ, HussainMA, etal. Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas. Diabetes 2000;49:741-8 (Pubitemid 30339989)
-
(2000)
Diabetes
, vol.49
, Issue.5
, pp. 741-748
-
-
Stoffers, D.A.1
Kieffer, T.J.2
Hussain, M.A.3
Drucker, D.J.4
Bonner-Weir, S.5
Habener, J.F.6
Egan, J.M.7
-
33
-
-
0141461415
-
Glucagon-like peptide-1 receptor is involved in learning and neuroprotection
-
DOI 10.1038/nm919
-
During M, Cao L, Zuzga D, et al. Glucagon-like peptide-1 receptor is involved in learning and neuroprotection. Nature Medicine 2003;9:1173-9 (Pubitemid 37173702)
-
(2003)
Nature Medicine
, vol.9
, Issue.9
, pp. 1173-1179
-
-
During, M.J.1
Cao, L.2
Zuzga, D.S.3
Francis, J.S.4
Fitzsimons, H.L.5
Jiao, X.6
Bland, R.J.7
Klugmann, M.8
Banks, W.A.9
Drucker, D.J.10
Haile, C.N.11
-
34
-
-
0038248960
-
Glucagon-like peptide-1 decreases endogenous amyloid-β peptide (Aβ) levels and protects hippocampal neurons from death induced by Aβ and iron
-
DOI 10.1002/jnr.10611
-
Perry TA, Lahiri D, Sambamurti K, et al. Glucagon-like peptide-1 decreases endogenous amyloid-^ peptide (Ap) levels and protects hippocampal neurons from death induced by Ap and iron. J Neurosci Res 2003;72:603-12 (Pubitemid 36578646)
-
(2003)
Journal of Neuroscience Research
, vol.72
, Issue.5
, pp. 603-612
-
-
Perry, T.1
Lahiri, D.K.2
Sambamurti, K.3
Chen, D.4
Mattson, M.P.5
Egan, J.M.6
Greig, N.H.7
-
35
-
-
77649187436
-
Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: A link between diabetes and Alzheimer's disease
-
McClean PL, Gault VA, Harriott P, et al. Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: a link between diabetes and Alzheimer's disease. Eur J Pharmacol 2010;630:158-62
-
(2010)
Eur J Pharmacol
, vol.630
, pp. 158-62
-
-
McClean, P.L.1
Gault, V.A.2
Harriott, P.3
-
36
-
-
79951592496
-
Impairment of synaptic plasticity and learning in GLP-1 receptor knockout mice: Interaction between type 2 diabetes and Alzheimer's Disease
-
(abstract 252)
-
McClean PL, Abbas T, Faivre E, et al. Impairment of synaptic plasticity and learning in GLP-1 receptor knockout mice: interaction between type 2 diabetes and Alzheimer's Disease. Diabetologia 2009;52(Suppl 1):S109 (abstract 252)
-
(2009)
Diabetologia
, vol.52
, Issue.SUPPL. 1
-
-
McClean, P.L.1
Abbas, T.2
Faivre, E.3
-
37
-
-
0032957382
-
Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective
-
DOI 10.1038/7449
-
Young D, Lawlor PA, Leone P, et al. Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective. Nat Med 1999;5:448-53 (Pubitemid 29180587)
-
(1999)
Nature Medicine
, vol.5
, Issue.4
, pp. 448-453
-
-
Young, D.1
Lawlor, P.A.2
Leone, P.3
Dragunow, M.4
During, M.J.5
-
38
-
-
0035576894
-
Neuroprotective peptide drug delivery and development: Potential new therapeutics
-
DOI 10.1016/S0166-2236(00)01931-7, PII S0166223600019317
-
Gozes I. Neuroprotective peptide drug delivery and development: potential new therapeutics. Trends Neurosci 2001;24:700-5 (Pubitemid 33097536)
-
(2001)
Trends in Neurosciences
, vol.24
, Issue.12
, pp. 700-705
-
-
Gozes, I.1
-
39
-
-
79951599503
-
-
London, UK: European Medicines Agency Available at [Last accessed 8 July 2010]
-
European Medicines Agency Scientific Discussion of exenatide. London, UK: European Medicines Agency, 2006. Available at http://www.ema.europa.eu/ humandocs/PDFs/EPAR/byetta/H-698-en6.pdf [Last accessed 8 July 2010]
-
(2006)
European Medicines Agency Scientific Discussion of Exenatide
-
-
-
40
-
-
0034752734
-
Pharmacokinetic actions of exendin-4 in the rat: Comparison with glucagon-like peptide-1
-
DOI 10.1002/ddr.1195
-
ParkesD, JodkaC, Smith P, etal. Pharmacokinetic actions of exendin-4 in the rat: comparison with glucagon-like peptide-1. Drug Dev Res 2001;54:260-7 (Pubitemid 33029654)
-
(2001)
Drug Development Research
, vol.53
, Issue.4
, pp. 260-267
-
-
Parkes, D.1
-
41
-
-
67649331128
-
-
Indianapolis, IN: Eli Lilly and Company Available at [Last accessed 8 July 2010]
-
Byetta® prescribing information. Indianapolis, IN: Eli Lilly and Company,2009. Available at http://pi.lilly.com/us/byetta-pi.pdf [Last accessed 8 July 2010]
-
(2009)
Byetta® Prescribing Information
-
-
-
42
-
-
0037349072
-
Entry of exendin-4 into brain is rapid but may be limited at high doses
-
DOI 10.1038/sj.ijo.0802206
-
Kastin AJ, Akerstrom V. Entry of exendin-4 into brain is rapid but may be limited at high doses. Int J Obes Relat Metab Disord 2003;27:313-18 (Pubitemid 36384867)
-
(2003)
International Journal of Obesity
, vol.27
, Issue.3
, pp. 313-318
-
-
Kastin, A.J.1
Akerstrom, V.2
-
43
-
-
38149083367
-
Protective effects of GLP-1 analogues exendin-4 and GLP-1(9-36) amide against ischemia-reperfusion injury in rat heart
-
Sonne DP, Engstrøm T, Treiman M. Protective effects of GLP-1 analogues exendin-4 and GLP-1(9-36) amide against ischemia-reperfusion injury in rat heart. Regul Pept 2008;146:243-9
-
(2008)
Regul Pept
, vol.146
, pp. 243-9
-
-
Sonne, D.P.1
Engstrøm, T.2
Treiman, M.3
-
44
-
-
0036676385
-
Pharmacokinetics, pharmacodynamics, safety, and tolerability of a single-dose of NN2211, a long-acting glucagon-like peptide 1 derivative, in healthy male subjects
-
DOI 10.2337/diacare.25.8.1398
-
Elbrønd B, Jakobsen G, Larsen S, etal. Pharmacokinetics, pharmacodynamics, safety, and tolerability of a single-dose of NN2211, a long-acting gluca-gon-like peptide 1 derivative, in healthy male subjects. Diabetes Care 2002;25:1398-404 (Pubitemid 41071152)
-
(2002)
Diabetes Care
, vol.25
, Issue.8
, pp. 1398-1404
-
-
Elbrond, B.1
Jakobsen, G.2
Larsen, S.3
Agerso, H.4
Jensen, L.B.5
Rolan, P.6
Sturis, J.7
Hatorp, V.8
Zdravkovic, M.9
-
45
-
-
77952362702
-
-
Bagsvaerd, Denmark: Novo Nordisk A/S Available [Last accessed 8 July 2010]
-
Victoza® Prescribing information. Bagsvaerd, Denmark: Novo Nordisk A/S, 2010. Available athttp://www.victoza.com/pdf/PI-(1-Column-Format).pdf [Last accessed 8 July 2010]
-
(2010)
Victoza® Prescribing Information
-
-
-
46
-
-
33746800119
-
Investigational treatments for Type 2 diabetes mellitus: Exenatide and liraglutide
-
DOI 10.1517/13543784.15.8.887
-
Gonzalez C, Beruto V, Keller G, et al. Investigational treatments for type 2 diabetes mellitus: exenatide and liraglutide. Expert Opin Invest Drugs 2006;15:887-95 (Pubitemid 44177842)
-
(2006)
Expert Opinion on Investigational Drugs
, vol.15
, Issue.8
, pp. 887-895
-
-
Gonzalez, C.1
Beruto, V.2
Keller, G.3
Santoro, S.4
Di Girolamo, G.5
-
47
-
-
74249114217
-
Current antihyperglycemic treatment strategies for patients with type 2 diabetes mellitus
-
Blonde L. Current antihyperglycemic treatment strategies for patients with type 2 diabetes mellitus. Cleve Clin J Med. 2009;76(Suppl 5):S4-11
-
(2009)
Cleve Clin J Med.
, vol.76
, Issue.SUPPL. 5
-
-
Blonde, L.1
-
48
-
-
69949163754
-
Exenatide and liraglutide: Different approaches to develop GLP-1 receptor agonists (incretin mimetics)-preclinical and clinical results
-
Madsbad S. Exenatide and liraglutide: different approaches to develop GLP-1 receptor agonists (incretin mimetics)-preclinical and clinical results. Best Pract Res Clin Endocrinol Metab 2009;23:463-77
-
(2009)
Best Pract Res Clin Endocrinol Metab
, vol.23
, pp. 463-77
-
-
Madsbad, S.1
-
49
-
-
0029903111
-
Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I
-
Orskov C, Poulsen SS, Møller M, et al. Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I. Diabetes 1996;45:832-5 (Pubitemid 26168585)
-
(1996)
Diabetes
, vol.45
, Issue.6
, pp. 832-835
-
-
Orskov, C.1
Poulsen, S.S.2
Moller, M.3
Holst, J.J.4
-
50
-
-
77956301808
-
Preproglucagon derived peptides GLP-1,GLP-2 and oxyntomodulin in the CNS: Role of peripherally secreted and centrally produced peptides
-
Vrang N, Larsen PJ. Preproglucagon derived peptides GLP-1, GLP-2 and oxyntomodulin in the CNS: role of peripherally secreted and centrally produced peptides. Prog Neurobiol 2010;92:442-62
-
(2010)
Prog Neurobiol
, vol.92
, pp. 442-62
-
-
Vrang, N.1
Larsen, P.J.2
-
51
-
-
77949837737
-
Lesions of area postrema and subfornical organ alter exendin-4-induced brain activation without preventing the hypophagic effect of the GLP-1 receptor agonist
-
Baraboi ED, Smith P, Ferguson AV, et al. Lesions of area postrema and subfornical organ alter exendin-4-induced brain activation without preventing the hypophagic effect of the GLP-1 receptor agonist. Am J Physiol Regul Integr Comp Physiol 2010;298:R1098-110
-
(2010)
Am J Physiol Regul Integr Comp Physiol
, vol.298
-
-
Baraboi, E.D.1
Smith, P.2
Ferguson, A.V.3
-
52
-
-
79951634443
-
Liraglutide regulates key hypothalamic appetite-related signals in diet-induced obese rats
-
(abstract 583-P)
-
Vrang N, Jelsing J, Raun K, et al. Liraglutide regulates key hypothalamic appetite-related signals in diet-induced obese rats. Diabetes 2010;59(Suppl 1):A159 (abstract 583-P)
-
(2010)
Diabetes
, vol.59
, Issue.SUPPL. 1
-
-
Vrang, N.1
Jelsing, J.2
Raun, K.3
-
53
-
-
79951617559
-
The GLP-1 analog liraglutide activates brainstem and hypothalamic neurons involved in appetite regulation
-
(abstract 584-P)
-
Raun K, Vrang N, Jelsing J, et al. The GLP-1 analog liraglutide activates brainstem and hypothalamic neurons involved in appetite regulation. Diabetes 2010;59(Suppl 1):A159 (abstract 584-P)
-
(2010)
Diabetes
, vol.59
, Issue.SUPPL. 1
-
-
Raun, K.1
Vrang, N.2
Jelsing, J.3
-
54
-
-
33846006173
-
The incretin system: Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
-
DOI 10.1016/S0140-6736(06)69705-5, PII S0140673606697055
-
Drucker D, Nauck M. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptiylpeptidase-4 inhibitors in type 2 diabetes. Lancet 2006;368:1696-705 (Pubitemid 46048557)
-
(2006)
Lancet
, vol.368
, Issue.9548
, pp. 1696-1705
-
-
Drucker, D.J.1
Nauck, M.A.2
-
55
-
-
77952309372
-
Liraglutide versus sitagliptin in patients with type 2 diabetes who did not have adequate glycaemic control with metformin: A 26-week, randomised, parallel-group, open-label trial
-
Pratley R, Nauck M, Bailey T, et al. Liraglutide versus sitagliptin in patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial. Lancet 2010;375:1447-56
-
(2010)
Lancet
, vol.375
, pp. 1447-56
-
-
Pratley, R.1
Nauck, M.2
Bailey, T.3
-
56
-
-
77956920722
-
Liraglutide: Effects beyond glycaemic control in diabetes treatment
-
McGill J. Liraglutide: effects beyond glycaemic control in diabetes treatment. Int J Clin Pract 201064:28-34
-
(2010)
Int J Clin Pract
, vol.64
, pp. 28-34
-
-
McGill, J.1
-
57
-
-
57749109119
-
The dipeptidyl peptidase-4 inhibitor vildagliptin increases portal concentrations of active GLP-1 to a greater extent that the peripheral concentrations
-
Hjøllund KR, HughesTE, Deacon CF, etal. The dipeptidyl peptidase-4 inhibitor vildagliptin increases portal concentrations of active GLP-1 to a greater extent that the peripheral concentrations. Diabetologia 2008;57:A411
-
(2008)
Diabetologia
, vol.57
-
-
Hjøllund, K.R.1
Hughes, T.E.2
Deacon, C.F.3
-
58
-
-
0036198285
-
Interactions of glucagon-like peptide-1 (GLP-1) with the blood-brain barrier
-
Kastin AJ, Akerstrom V, Pan W. Interactions of glucagon-like peptide-1 (GLP-1) with the blood-brain barrier. J Mol Neurosci 2002;18:7-14 (Pubitemid 34252619)
-
(2002)
Journal of Molecular Neuroscience
, vol.18
, Issue.1-2
, pp. 7-14
-
-
Kastin, A.J.1
Akerstrom, V.2
Pan, W.3
-
59
-
-
79951588488
-
Novel GLP-1 analogues can cross the blood brain barrier and enhance synaptic plasticity in the brain: A link between diabetes and Alzheimer's Disease
-
(abstract 790)
-
Hölscher C, Fung K, McCurtin R, et al. Novel GLP-1 analogues can cross the blood brain barrier and enhance synaptic plasticity in the brain: a link between diabetes and Alzheimer's Disease. Diabetologia 2009;52(Suppl 1):S311 (abstract 790)
-
(2009)
Diabetologia
, vol.52
, Issue.SUPPL. 1
-
-
Hölscher, C.1
Fung, K.2
McCurtin, R.3
-
60
-
-
9944251347
-
Glucagon-like peptide-1 relaxes rat conduit arteries via an endothelium-independent mechanism
-
DOI 10.1016/j.regpep.2004.08.024, PII S0167011504003179
-
Nystrom T, Gonon AT, Sjoholm A, et al. Glucagon-like peptide-1 relaxes rat conduit arteries via an endothelium-independent mechanism. Regul Pept 2005;125:173-7 (Pubitemid 39593722)
-
(2005)
Regulatory Peptides
, vol.125
, Issue.1-3
, pp. 173-177
-
-
Nystrom, T.1
Gonon, A.T.2
Sjoholm, A.3
Pernow, J.4
-
61
-
-
52049093652
-
GLP-1 and related peptides cause concentration-dependent relaxation of rat aorta through a pathway involving KATP and cAMP
-
Green BD, Hand KV, Dougan JE, et al. GLP-1 and related peptides cause concentration-dependent relaxation of rat aorta through a pathway involving KATP and cAMP. Arch Biochem Biophys 2008;478:136-42
-
(2008)
Arch Biochem Biophys
, vol.478
, pp. 136-42
-
-
Green, B.D.1
Hand, K.V.2
Dougan, J.E.3
-
62
-
-
0036721411
-
Functional maturation of fetal porcine β-cells by glucagon-like peptide 1 and cholecystokinin
-
DOI 10.1210/en.2001-211344
-
Hardikar AA, Wang XY, Williams LJ, et al. Functional maturation of fetal porcine j6-cells by glucagon-like peptide 1 and cholecystokinin. Endocrinology 2002;143:3505-14 (Pubitemid 34925725)
-
(2002)
Endocrinology
, vol.143
, Issue.9
, pp. 3505-3514
-
-
Hardikar, A.A.1
Wang, X.Y.2
Williams, L.J.3
Kwok, J.4
Wong, R.5
Yao, M.6
Tuch, B.E.7
-
63
-
-
0036775170
-
Exendin 4 up-regulates expression of PDX 1 and hastens differentiation and maturation of human fetal pancreatic cells
-
DOI 10.1210/jc.2002-020137
-
Movassat J, Beattie GM, Lopez AD, et al. Exendin 4 up-regulates expression of PDX1 and hastens differentiation and maturation of human fetal pancreatic cells. J Clin Endocrinol Metab 2002;87:4775-81 (Pubitemid 35247075)
-
(2002)
Journal of Clinical Endocrinology and Metabolism
, vol.87
, Issue.10
, pp. 4775-4781
-
-
Movassat, J.1
Beattie, G.M.2
Lopez, A.D.3
Hayek, A.4
-
64
-
-
0036323269
-
Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells
-
DOI 10.1210/en.143.8.3152
-
Abraham EJ, Leech CA, Lin JC, et al. Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells. Endocrinology 2002;143:3152-61 (Pubitemid 34809888)
-
(2002)
Endocrinology
, vol.143
, Issue.8
, pp. 3152-3161
-
-
Abraham, E.J.1
Leech, C.A.2
Lin, J.C.3
Zulewski, H.4
Habener, J.F.5
-
65
-
-
0029958404
-
Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene
-
DOI 10.1038/nm1196-1254
-
Scrocchi LA, Brown TJ, MaClusky N, et al. Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene. Nat Med 1996;2:1254-8 (Pubitemid 26375413)
-
(1996)
Nature Medicine
, vol.2
, Issue.11
, pp. 1254-1258
-
-
Scrocchi, L.A.1
Brown, T.J.2
MacLusky, N.3
Brubaker, P.L.4
Auerbach, A.B.5
Joyner, A.L.6
Drucker, D.J.7
-
66
-
-
0036182251
-
A novel neurotrophic property of glucagon-like peptide 1: A promoter of nerve growth factor-mediated differentiation in PC12 cells
-
DOI 10.1124/jpet.300.3.958
-
Perry T, Lahiri DK, Chen D, et al. A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells. J Pharmacol Exp Ther 2002;300:958-66 (Pubitemid 34165002)
-
(2002)
Journal of Pharmacology and Experimental Therapeutics
, vol.300
, Issue.3
, pp. 958-966
-
-
Perry, T.1
Lahiri, D.K.2
Chen, D.3
Zhou, J.I.E.4
Shaw, K.T.Y.5
Egan, J.M.6
Greig, N.H.7
-
67
-
-
78149466370
-
Differentiating effects of the glucagon-like peptide-1 analogue exendin-4 in a human neuronal cell model
-
Luciani P, Deledda C, Benvenuti S, et al. Differentiating effects of the glucagon-like peptide-1 analogue exendin-4 in a human neuronal cell model. Cell Mol Life Sci 2010;67:3711-23
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 3711-23
-
-
Luciani, P.1
Deledda, C.2
Benvenuti, S.3
-
68
-
-
67649476077
-
Incretin therapies: Effects beyond glycemic control
-
Mudaliar S, Henry RR. Incretin therapies: effects beyond glycemic control. Eur J Intern Med 2009;20(Suppl 2):S319-28
-
(2009)
Eur J Intern Med
, vol.20
, Issue.SUPPL. 2
-
-
Mudaliar, S.1
Henry, R.R.2
-
69
-
-
70350341465
-
Emerging cardiovascular actions of the incretin hormone glucagon-like peptide-1: Potential therapeutic actions beyond glycaemic control
-
Grieve D, Cassidy R, Green B. Emerging cardiovascular actions of the incretin hormone glucagon-like peptide-1: potential therapeutic actions beyond glycaemic control. Br J Pharmacol 2009;157:1340-51
-
(2009)
Br J Pharmacol
, vol.157
, pp. 1340-51
-
-
Grieve, D.1
Cassidy, R.2
Green, B.3
-
70
-
-
0036312680
-
Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the β-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4
-
Tourrel C, Bailbe D, Lacorne M, et al. Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the /S-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4. Diabetes 2002;51:1443-52 (Pubitemid 34826610)
-
(2002)
Diabetes
, vol.51
, Issue.5
, pp. 1443-1452
-
-
Tourrel, C.1
Bailbe, D.2
Lacorne, M.3
Meile, M.-J.4
Kergoat, M.5
Portha, B.6
-
71
-
-
0034522773
-
Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats
-
DOI 10.1210/en.141.12.4600
-
Perfetti R, Zhou J, Doyle ME, et al. Glucagon-like peptide-1 induces cell proliferation and pancreatic duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose intolerant rats. Endocrinology 2000;141:4600-5 (Pubitemid 32055138)
-
(2000)
Endocrinology
, vol.141
, Issue.12
, pp. 4600-4605
-
-
Perfetti, R.1
Zhou, J.I.E.2
Doyle, M.E.3
Egan, J.M.4
-
72
-
-
0036784675
-
The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases beta-cell mass in diabetic mice
-
Rolin B, Larsen MO, Gotfredsen CF, et al. The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases beta-cell mass in diabetic mice. Am J Physiol Endocrinol Metab 2002;283:E745-52
-
(2002)
Am J Physiol Endocrinol Metab
, vol.283
-
-
Rolin, B.1
Larsen, M.O.2
Gotfredsen, C.F.3
-
73
-
-
38849196303
-
Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease
-
DOI 10.1002/jnr.21483
-
Bertilsson G, Patrone C, Zachrisson O, et al. Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease. J Neurosci Res 2008;86:326-38 (Pubitemid 351196738)
-
(2008)
Journal of Neuroscience Research
, vol.86
, Issue.2
, pp. 326-338
-
-
Bertilsson, G.1
Patrone, C.2
Zachrisson, O.3
Andersson, A.4
Dannaeus, K.5
Heidrich, J.6
Kortesmaa, J.7
Mercer, A.8
Nielsen, E.9
Ronnholm, H.10
Wikstrom, L.11
-
74
-
-
72749091486
-
Ciliary neurotrophic factor recruitment of glucagon-like peptide-1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons
-
Belsham D, Fick L, Dalvi P, et al. Ciliary neurotrophic factor recruitment of glucagon-like peptide-1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons. FASEB J 2009;23: 4256-65
-
(2009)
FASEB J
, vol.23
, pp. 4256-65
-
-
Belsham, D.1
Fick, L.2
Dalvi, P.3
-
75
-
-
4344605042
-
Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy
-
DOI 10.1161/01.CIR.0000139339.85840.DD
-
Nikolaidis LA, Elahi D, Hentosz T, et al. Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy. Circulation 2004;110:955-61 (Pubitemid 39128621)
-
(2004)
Circulation
, vol.110
, Issue.8
, pp. 955-961
-
-
Nikolaidis, L.A.1
Elahi, D.2
Hentosz, T.3
Doverspike, A.4
Huerbin, R.5
Zourelias, L.6
Stolarski, C.7
Shen, Y.-T.8
Shannon, R.P.9
-
76
-
-
1442311383
-
Effects of Glucagon-Like Peptide-1 in Patients with Acute Myocardial Infarction and Left Ventricular Dysfunction after Successful Reperfusion
-
DOI 10.1161/01.CIR.0000120505.91348.58
-
Nikolaidis LA, Mankad S, Sokos GG, etal. Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion. Circulation 2004;109:962-5 (Pubitemid 38282847)
-
(2004)
Circulation
, vol.109
, Issue.8
, pp. 962-965
-
-
Nikolaidis, L.A.1
Mankad, S.2
Sokos, G.G.3
Miske, G.4
Shah, A.5
Elahi, D.6
Shannon, R.P.7
-
77
-
-
66749102158
-
The extrapancreatic effects of glucagon-like peptide-1 and related peptides
-
Abu-Hamdah R, Rabiee A, Meneilly G, et al. The extrapancreatic effects of glucagon-like peptide-1 and related peptides. J Clin Endocrinol Metab 2009;94:1843-52
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 1843-52
-
-
Abu-Hamdah, R.1
Rabiee, A.2
Meneilly, G.3
-
78
-
-
0036828227
-
Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats
-
DOI 10.1210/en.2002-220405
-
Farilla L, Hui H, Bertolotto C, et al. Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. Endocrinology 2002;143:4397-408 (Pubitemid 35239574)
-
(2002)
Endocrinology
, vol.143
, Issue.11
, pp. 4397-4408
-
-
Farilla, L.1
Hongxiang, H.2
Bertolotto, C.3
Kang, E.4
Bulotta, A.5
Mario, U.D.I.6
Perfetti, R.7
-
79
-
-
0036381989
-
Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice
-
Wang Q, Brubaker PL. Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice. Diabetologia 2002;45:1263-73
-
(2002)
Diabetologia
, vol.45
, pp. 1263-73
-
-
Wang, Q.1
Brubaker, P.L.2
-
80
-
-
2942568445
-
Glucagon-like peptide-1 prevents beta cell glucolipotoxicity
-
DOI 10.1007/s00125-004-1379-6
-
Buteau J, El-Assaad W, Rhodes CJ, et al. Glucagon-like peptide-1 prevents beta cell glucolipotoxicity. Diabetologia 2004;47:806-15 (Pubitemid 38756992)
-
(2004)
Diabetologia
, vol.47
, Issue.5
, pp. 806-815
-
-
Buteau, J.1
El-Assaad, W.2
Rhodes, C.J.3
Mosenberg, L.4
Joly, E.5
Prentki, M.6
-
81
-
-
0037414781
-
Glucagon-like peptide-1 receptor signaling modulates β cell apoptosis
-
DOI 10.1074/jbc.M209423200
-
Li Y, Hansotia T, Yusta B, et al. Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis. J Biol Chem 2003;278:471-8 (Pubitemid 36043598)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.1
, pp. 471-478
-
-
Li, Y.1
Hansotia, T.2
Yusta, B.3
Ris, F.4
Halban, P.A.5
Drueker, D.J.6
-
82
-
-
77951246517
-
Glucagon-like peptide-1 increases beta-cell glucose competence and proliferation by translational induction of insulin-like growth factor-1 receptor expression
-
Cornu M, Modi H, Kawamori D, et al. Glucagon-like peptide-1 increases beta-cell glucose competence and proliferation by translational induction of insulin-like growth factor-1 receptor expression. J Biol Chem 2010;285: 10538-45
-
(2010)
J Biol Chem
, vol.285
, pp. 10538-45
-
-
Cornu, M.1
Modi, H.2
Kawamori, D.3
-
83
-
-
68049136013
-
Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop
-
Cornu M, Yang JY, Jaccard E, et al. Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop. Diabetes 2009;58:1816-25
-
(2009)
Diabetes
, vol.58
, pp. 1816-25
-
-
Cornu, M.1
Yang, J.Y.2
Jaccard, E.3
-
84
-
-
48449104756
-
Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway
-
Ferdaoussi M, Abdelli S, Yang JY, et al. Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway. Diabetes 2008;57:1205-15
-
(2008)
Diabetes
, vol.57
, pp. 1205-15
-
-
Ferdaoussi, M.1
Abdelli, S.2
Yang, J.Y.3
-
85
-
-
47149095990
-
Pancreatic alpha-cell dysfunction in diabetes
-
Burcelin R, Knauf C, Cani PD. Pancreatic alpha-cell dysfunction in diabetes. Diabetes Metab 2008;34(Suppl 2):S49-55
-
(2008)
Diabetes Metab
, vol.34
, Issue.SUPPL. 2
-
-
Burcelin, R.1
Knauf, C.2
Cani, P.D.3
-
87
-
-
0023638829
-
Glucagon-like peptide-1 7-36: A physiological incretin in man
-
Kreymann B, Ghatei MA, Williams G, et al. Glucagon-like peptide-1 7-36: a physiological incretin in man. Lancet 1987;2:1300-4 (Pubitemid 17156636)
-
(1987)
Lancet
, vol.2
, Issue.8571
, pp. 1300-1304
-
-
Kreymann, B.1
Williams, G.2
Ghatei, M.A.3
Bloom, S.R.4
-
88
-
-
0033512486
-
Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells
-
Zhou J, Wang X, Pineyro MA, et al. Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells. Diabetes 1999;48:2358-66 (Pubitemid 30395427)
-
(1999)
Diabetes
, vol.48
, Issue.12
, pp. 2358-2366
-
-
Zhou, J.1
Wang, X.2
Pineyro, M.A.3
Egan, J.M.4
-
89
-
-
79951662884
-
Liraglutide: Shortlived effect on gastric emptying, long-lasting effects on body weight
-
(abstract 591-P)
-
Bjerre Knudsen L, Tang-Christensen M, Jelsing J, et al. Liraglutide: shortlived effect on gastric emptying, long-lasting effects on body weight. Diabetes 2010;59(Suppl 1):A161 (abstract 591-P)
-
(2010)
Diabetes
, vol.59
, Issue.SUPPL. 1
-
-
Bjerre Knudsen, L.1
Tang-Christensen, M.2
Jelsing, J.3
-
90
-
-
77953094551
-
Enhancing the GLP-1 receptor signaling pathway leads to proliferation and neuroprotection in human neuroblastoma cells
-
Li Y, Tweedie D, Mattson MP, et al. Enhancing the GLP-1 receptor signaling pathway leads to proliferation and neuroprotection in human neuroblastoma cells. J Neurochem 2010;113:1621-31
-
(2010)
J Neurochem
, vol.113
, pp. 1621-31
-
-
Li, Y.1
Tweedie, D.2
Mattson, M.P.3
-
91
-
-
0030068620
-
Gastric emptying, glucose response, and insulin secretion after a liquid test meal: Effects of exogenous glucagon-like peptide-1 (GLP-1)-( 7-36) amide in type 2 (noninsulin-dependent) diabetic patients
-
Willms B, Werner J, Holst JJ, et al. Gastric emptying, glucose response, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients. J Clin Endocrinol Metab 1996;81:327-32
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 327-32
-
-
Willms, B.1
Werner, J.2
Holst, J.J.3
-
92
-
-
0036959991
-
Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers
-
DOI 10.1210/jc.87.3.1239
-
Nauck MA, Heimesaat MM, Behle K, et al. Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers. J Clin Endocrinol Metab 2002;87: 1239-46 (Pubitemid 36121094)
-
(2002)
Journal of Clinical Endocrinology and Metabolism
, vol.87
, Issue.3
, pp. 1239-1246
-
-
Nauck, M.A.1
Heimesaat, M.M.2
Behle, K.3
Holst, J.J.4
Nauck, M.S.5
Ritzel, R.6
Hufner, M.7
Schmiegel, W.H.8
-
93
-
-
33746619693
-
Glucagon-like peptide-1 is involved in sodium and water homeostasis in humans
-
DOI 10.1159/000094334
-
Gutzwiller JP, Hruz P, Huber AR, et al. Glucagon-like peptide-1 is involved in sodium and water homeostasis in humans. Digestion 2006;73:142-50 (Pubitemid 44155916)
-
(2006)
Digestion
, vol.73
, Issue.2-3
, pp. 142-150
-
-
Gutzwiller, J.-P.1
Hruz, P.2
Huber, A.R.3
Hamel, C.4
Zehnder, C.5
Drewe, J.6
Gutmann, H.7
Stanga, Z.8
Vogel, D.9
Beglinger, C.10
-
94
-
-
2942668372
-
Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men
-
DOI 10.1210/jc.2003-031403
-
Gutzwiller JP, Tschopp S, Bock A, et al. Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men. J Clin Endocrinol Metab 2004;89:3055-61 (Pubitemid 38766408)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.6
, pp. 3055-3061
-
-
Gutzwiller, J.-P.1
Tschopp, S.2
Bock, A.3
Zehnder, C.E.4
Huber, A.R.5
Kreyenbuehl, M.6
Gutmann, H.7
Drewe, J.8
Henzen, C.9
Goeke, B.10
Beglinger, C.11
-
95
-
-
0345726358
-
Glucagon-like peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites
-
Yamamoto H, Kishi T, Lee CE, et al. Glucagon-like peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites. J Neurosci 2003;23: 2939-46 (Pubitemid 36418630)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.7
, pp. 2939-2946
-
-
Yamamoto, H.1
Kishi, T.2
Lee, C.E.3
Choi, B.J.4
Fang, H.5
Hollenberg, A.N.6
Drucker, D.J.7
Elmquist, J.K.8
-
96
-
-
0042831025
-
Do apoptotic mechanisms regulate synaptic plasticity and growth-cone motility?
-
DOI 10.1385/NMM:2:2:197
-
Gilman CP, Mattson MP. Do apoptotic mechanisms regulate synaptic plasticity and growth-cone motility? Neuromolecular Med 2002;2:197-214 (Pubitemid 37012504)
-
(2002)
NeuroMolecular Medicine
, vol.2
, Issue.2
, pp. 197-214
-
-
Gilman, C.P.1
Mattson, M.P.2
-
97
-
-
0023931488
-
Outgrowth-regulating actions of glutamate in isolated hippocampal pyramidal neurons
-
Mattson MP, Dou P, Kater SB. Outgrowth-regulating actions of glutamate in isolated hippocampal pyramidal neurons. J Neurosci 1988;8:2087-100
-
(1988)
J Neurosci
, vol.8
, pp. 2087-100
-
-
Mattson, M.P.1
Dou, P.2
Kater, S.B.3
-
98
-
-
0024109358
-
Interactions between entorhinal axons and target hippocampal neurons: A role for glutamate in the development of hippocampal circuitry
-
Mattson MP, Lee RE, Adams ME, et al. Interactions between entorhinal axons and target hippocampal neurons: a role for glutamate in the development of hippocampal circuitry. Neuron 1988;1:865-76
-
(1988)
Neuron
, vol.1
, pp. 865-76
-
-
Mattson, M.P.1
Lee, R.E.2
Adams, M.E.3
-
99
-
-
14944371918
-
New therapeutic strategies and drug candidates for neurodegenerative diseases: P53 and TNF-α inhibitors, and GLP-1 receptor agonists
-
DOI 10.1196/annals.1332.018
-
Greig N, Mattson M, Perry TA, et al. New therapeutic strategies and drug candidates for neurodegenerative diseases. P53 and TNF-a inhibitors, and GLP-1 receptor agonists. Ann N Y Acad Sci 2004;1035:290-315 (Pubitemid 40362340)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1035
, pp. 290-315
-
-
Greig, N.H.1
Mattson, M.P.2
Perry, T.3
Chan, S.L.4
Giordano, T.5
Sambamurti, K.6
Rogers, J.T.7
Ovadia, H.8
Lahiri, D.K.9
-
100
-
-
77954953382
-
New roles for insulin-like hormones in neuronal signalling and protection: New hopes for novel treatments of Alzheimer's disease?
-
doi:10.1016/j.neurobiolaging.2008.08.023
-
Hö lscher C, Li L. New roles for insulin-like hormones in neuronal signalling and protection: New hopes for novel treatments of Alzheimer's disease? Neurobiol Aging 2008 doi:10.1016/j.neurobiolaging.2008.08.023
-
(2008)
Neurobiol Aging
-
-
Hölscher, C.1
Li, L.2
-
101
-
-
59049087723
-
GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism
-
Li Y, Perry TA, Kindy M, et al. GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism. PNAS 2009;106:1285-90
-
(2009)
PNAS
, vol.106
, pp. 1285-90
-
-
Li, Y.1
Perry, T.A.2
Kindy, M.3
-
102
-
-
1242316296
-
Insulin and neurodegenerative disease: Shared and specific mechanisms
-
DOI 10.1016/S1474-4422(04)00681-7
-
Craft S, Watson GS. Insulin and neurodegenerative disease: shared and specific mechanisms. Lancet Neurol 2004;3:169-78 (Pubitemid 38229951)
-
(2004)
Lancet Neurology
, vol.3
, Issue.3
, pp. 169-178
-
-
Craft, S.1
Watson, G.S.2
-
103
-
-
67649682161
-
Adiposity, type 2 diabetes and Alzheimer's disease
-
Luchsinger JA, Gustafson D. Adiposity, type 2 diabetes and Alzheimer's disease. J Alzheimers Dis 2009;16:693-704
-
(2009)
J Alzheimers Dis
, vol.16
, pp. 693-704
-
-
Luchsinger, J.A.1
Gustafson, D.2
-
104
-
-
42249094013
-
Adiposity, hyperinsulinemia, diabetes and Alzheimer's disease: An epidemiological perspective
-
Luchsinger JA. Adiposity, hyperinsulinemia, diabetes and Alzheimer's disease: an epidemiological perspective. Eur J Pharmacol 2008;585: 119-29
-
(2008)
Eur J Pharmacol
, vol.585
, pp. 119-29
-
-
Luchsinger, J.A.1
-
105
-
-
77955084717
-
Why pleiotropic interventions are needed for Alzheimer's disease
-
Frautschy S, Cole G. Why pleiotropic interventions are needed for Alzheimer's disease. Mol Neurobiol 2010;41:392-409
-
(2010)
Mol Neurobiol
, vol.41
, pp. 392-409
-
-
Frautschy, S.1
Cole, G.2
-
106
-
-
54049136095
-
Insulin in combination with other diabetes medication is associated with less Alzheimer neuropathology
-
Beeri MS, Schmeidler J, Silverman JM, et al. Insulin in combination with other diabetes medication is associated with less Alzheimer neuropathology. Neurology 2008;71:750-7
-
(2008)
Neurology
, vol.71
, pp. 750-7
-
-
Beeri, M.S.1
Schmeidler, J.2
Silverman, J.M.3
-
107
-
-
0036370776
-
Advances in the cellular and molecular biology of the beta-amyloid protein in Alzheimer's disease
-
DOI 10.1385/NMM:1:1:1
-
Sambamurti K, Greig N, Lahiri D. Advances in the cellular and molecular biology of the beta-amyloid protein in Alzheimer's disease. Neuromolecular Med 2002;1:1-31 (Pubitemid 37021521)
-
(2002)
NeuroMolecular Medicine
, vol.1
, Issue.1
, pp. 1-31
-
-
Sambamurti, K.1
Greig, N.H.2
Lahiri, D.K.3
-
108
-
-
57049125529
-
Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: Parallels with Alzheimer's disease and correction by insulin
-
Jolivalt C, Lee C, Beiswenger K, et al. Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: parallels with Alzheimer's disease and correction by insulin. J Neurisci Res 2008;86:3265-74
-
(2008)
J Neurisci Res
, vol.86
, pp. 3265-74
-
-
Jolivalt, C.1
Lee, C.2
Beiswenger, K.3
-
109
-
-
18744438248
-
Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor
-
Xie L, Helmerhorst E, Taddei K, et al. Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor. J Neurosci 2002;22:RC221
-
(2002)
J Neurosci
, vol.22
-
-
Xie, L.1
Helmerhorst, E.2
Taddei, K.3
-
110
-
-
38049110692
-
Amyloid beta oligomers induce impairment of neuronal insulin receptors
-
Zhao W, De Felice F, Fernandez S, et al. Amyloid beta oligomers induce impairment of neuronal insulin receptors. Faseb J 2008;22:246-60
-
(2008)
Faseb J
, vol.22
, pp. 246-60
-
-
Zhao, W.1
De Felice, F.2
Fernandez, S.3
-
111
-
-
44149122563
-
GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid
-
Gault V, Holscher C. GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid. Eur J Pharmacol 2008;587:112-17
-
(2008)
Eur J Pharmacol
, vol.587
, pp. 112-17
-
-
Gault, V.1
Holscher, C.2
-
112
-
-
36949030831
-
GLP-1 amplifies insulin signaling by up-regulation of IRβ, IRS-1 and Glut4 in 3T3-L1 adipocytes
-
DOI 10.1007/s12020-007-9011-4
-
Gao H, Wang X, Zhang Z, et al. GLP-1 amplifies insulin signaling by up-regulation of IRbeta, IRS-1 and Glut4 in 3T3-L1 adipocytes. Endocrine 2007;32:90-5 (Pubitemid 350242552)
-
(2007)
Endocrine
, vol.32
, Issue.1
, pp. 90-95
-
-
Gao, H.1
Wang, X.2
Zhang, Z.3
Yang, Y.4
Yang, J.5
Li, X.6
Ning, G.7
-
113
-
-
77950352189
-
GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease
-
Li Y, Duffy K, Ottinger M, et al. GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease. J Alzheimers Dis 2010;19:1205-19
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 1205-19
-
-
Li, Y.1
Duffy, K.2
Ottinger, M.3
-
114
-
-
82755176046
-
Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice
-
doi:10.1016/j.neurobiolaging.2010.02.014
-
Gengler S, McClean PL, McCurtin R, et al. Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice. Neurobiol Aging 2010; doi:10.1016/j.neurobiolaging.2010.02.014
-
(2010)
Neurobiol Aging
-
-
Gengler, S.1
McClean, P.L.2
McCurtin, R.3
-
115
-
-
76749116176
-
Long-term inhibition of dipeptidyl peptidase-4 in Alzheimer's prone mice
-
D'Amico M, Di Filippo C, Marfella R, et al. Long-term inhibition of dipeptidyl peptidase-4 in Alzheimer's prone mice. Exp Gerontol 2010;45:202-7
-
(2010)
Exp Gerontol
, vol.45
, pp. 202-7
-
-
D'Amico, M.1
Di Filippo, C.2
Marfella, R.3
-
116
-
-
74749108848
-
Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes
-
Asmar M, Højberg PV, Deacon CF, et al. Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes. Regul Pept 2010;160:175-80
-
(2010)
Regul Pept
, vol.160
, pp. 175-80
-
-
Asmar, M.1
Højberg, P.V.2
Deacon, C.F.3
-
117
-
-
33747188115
-
Evaluation of the antidiabetic activity of DPP IV resistant N-terminally modified versus mid-chain acylated analogues of glucose-dependent insulinotropic polypeptide
-
DOI 10.1016/j.bcp.2006.06.013, PII S0006295206003601
-
Irwin, N, Clarke G, Green B, et al. Evaluation of the antidiabetic activity of DPP IV resistant N-terminally modified versus mid-chain acylated analogues of glucose-dependent insulinotropic polypeptide. Biochem Pharmacol 2006;72:719-28 (Pubitemid 44233552)
-
(2006)
Biochemical Pharmacology
, vol.72
, Issue.6
, pp. 719-728
-
-
Irwin, N.1
Clarke, G.C.2
Green, B.D.3
Greer, B.4
Harriott, P.5
Gault, V.A.6
O'Harte, F.P.M.7
Flatt, P.R.8
-
118
-
-
24944525045
-
Molecular pathogenesis of Parkinson's disease
-
DOI 10.1093/hmg/ddi308
-
Gandhi S, Wood N. Molecular pathogenesis of Parkinson's disease. Hum Mol Genet 2005;14:2749-55 (Pubitemid 41300647)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.18
, pp. 2749-2755
-
-
Gandhi, S.1
Wood, N.W.2
-
119
-
-
33845768784
-
Microglia-mediated neurotoxicity: Uncovering the molecular mechanisms
-
DOI 10.1038/nrn2038, PII NRN2038
-
Block ML, Zecca L, Hong J-S. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nature Neurosci 2007;8:57-69 (Pubitemid 46011999)
-
(2007)
Nature Reviews Neuroscience
, vol.8
, Issue.1
, pp. 57-69
-
-
Block, M.L.1
Zecca, L.2
Hong, J.-S.3
-
120
-
-
34247366072
-
Inflammation as a causative factor in the aetiology of Parkinson's disease
-
DOI 10.1038/sj.bjp.0707167, PII 0707167
-
Whitton P. Inflammation as a potential causative factor in the aetiology of Parkinsons disease. Br J Pharmacol 2007;150:963-76 (Pubitemid 46628616)
-
(2007)
British Journal of Pharmacology
, vol.150
, Issue.8
, pp. 963-976
-
-
Whitton, P.S.1
-
121
-
-
41149163183
-
Parkinson's disease: Clinical features and diagnosis
-
DOI 10.1136/jnnp.2007.131045
-
Jankovic J. Parkinson's disease: clinical features and diagnosis. J Neurol Neurosurg Psychiatry 2008;79:368-76 (Pubitemid 351441488)
-
(2008)
Journal of Neurology, Neurosurgery and Psychiatry
, vol.79
, Issue.4
, pp. 368-376
-
-
Jankovic, J.1
-
122
-
-
77953428393
-
Parkinson's disease: Health-related quality of life, economic cost, and implications of early treatment
-
Chen JJ. Parkinson's disease: health-related quality of life, economic cost, and implications of early treatment. Am J Manag Care 2010;16(Suppl Implications):S87-93
-
(2010)
Am J Manag Care
, vol.16
, Issue.SUPPL.
-
-
Chen, J.J.1
-
123
-
-
33846572874
-
Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030
-
DOI 10.1212/01.wnl.0000247740.47667.03, PII 0000611420070130000016
-
Dorsey ER, Constantinescu R, Thompson JP, et al. Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030. Neurology 2007;68:384-6 (Pubitemid 46184217)
-
(2007)
Neurology
, vol.68
, Issue.5
, pp. 384-386
-
-
Dorsey, E.R.1
Constantinescu, R.2
Thompson, J.P.3
Biglan, K.M.4
Holloway, R.G.5
Kieburtz, K.6
Marshall, F.J.7
Ravina, B.M.8
Schifitto, G.9
Siderowf, A.10
Tanner, C.M.11
-
124
-
-
34147190028
-
Type 2 diabetes and the risk of Parkinson's disease
-
DOI 10.2337/dc06-2011
-
Hu G, Jousilahti P, Bidel S, et al. Type 2 diabetes and the risk of Parkinson's disease. Diabetes Care 2007;30:842-7 (Pubitemid 46562366)
-
(2007)
Diabetes Care
, vol.30
, Issue.4
, pp. 842-847
-
-
Hu, G.1
Jousilahti, P.2
Bidel, S.3
Antikainen, R.4
Tuomilehto, J.5
-
125
-
-
70349334516
-
Exendin-4 protects dopaminergic neurons by inhibition of microglial activation abd matrix metalloproteinase-3 expression in an animal model of Parkinson's disease
-
Kim S, Moon M, Park S. Exendin-4 protects dopaminergic neurons by inhibition of microglial activation abd matrix metalloproteinase-3 expression in an animal model of Parkinson's disease. J Endocrinol 2009;202:431-9
-
(2009)
J Endocrinol
, vol.202
, pp. 431-9
-
-
Kim, S.1
Moon, M.2
Park, S.3
-
126
-
-
70449701437
-
Exendin-4, a GLP-1 receptor agonist, directly induces adiponectin expression through protein kinase A pathway and prevents inflammatory adipokine expression
-
Kim Chung le T, Hosaka T, Yoshida M, et al. Exendin-4, a GLP-1 receptor agonist, directly induces adiponectin expression through protein kinase A pathway and prevents inflammatory adipokine expression. Biochem Biophys Res Commun 2009;390:613-18
-
(2009)
Biochem Biophys Res Commun
, vol.390
, pp. 613-18
-
-
Kim Chung Le, T.1
Hosaka, T.2
Yoshida, M.3
-
127
-
-
67849084815
-
Glucagon-like peptide-1 protects mesenteric endothelium from injury during inflammation
-
Dozier KC, Cureton EL, Kwan RO, et al. Glucagon-like peptide-1 protects mesenteric endothelium from injury during inflammation. Peptides 2009;30:1735-41
-
(2009)
Peptides
, vol.30
, pp. 1735-41
-
-
Dozier, K.C.1
Cureton, E.L.2
Kwan, R.O.3
-
128
-
-
45549108268
-
Glucagon-like peptide 1 receptor stimulation reverses key deficits in distinct rodent models of Parkinson's disease
-
Harkavyi A, Abuirmeileh A, Lever R, et al. Glucagon-like peptide 1 receptor stimulation reverses key deficits in distinct rodent models of Parkinson's disease. J Neuroinflammation 2008;21;5:19
-
(2008)
J Neuroinflammation
, vol.21
, Issue.5
, pp. 19
-
-
Harkavyi, A.1
Abuirmeileh, A.2
Lever, R.3
-
129
-
-
8844220536
-
Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series
-
DOI 10.1038/sj.embor.7400250
-
Landles C, Bates GP. Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series. EMBO Rep 2004;5:958-63 (Pubitemid 39534452)
-
(2004)
EMBO Reports
, vol.5
, Issue.10
, pp. 958-963
-
-
Landles, C.1
Bates, G.P.2
-
130
-
-
77955398297
-
Uncovering the true prevalence of Huntington's disease
-
doi:10.1016/S1474-4422(10)70160-5
-
Spinney L. Uncovering the true prevalence of Huntington's disease. Lancet Neurol 2010; doi:10.1016/S1474-4422(10)70160-5
-
(2010)
Lancet Neurol
-
-
Spinney, L.1
-
131
-
-
63249091158
-
Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntingdon's disease
-
Martin B, Golden E, Carlson OD, et al. Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntingdon's disease. Diabetes 2009;58:318-28
-
(2009)
Diabetes
, vol.58
, pp. 318-28
-
-
Martin, B.1
Golden, E.2
Carlson, O.D.3
-
132
-
-
36549030256
-
Hypothalamic dysfunction and neuroendocrine and metabolic alterations in Huntington's disease: Clinical consequences and therapeutic implications
-
Aziz N, Swaab D, Pijl H, et al. Hypothalamic dysfunction and neuroendocrine and metabolic alterations in Huntington's disease: clinical consequences and therapeutic implications. Rev Neurosci 2007;18:223-51
-
(2007)
Rev Neurosci
, vol.18
, pp. 223-51
-
-
Aziz, N.1
Swaab, D.2
Pijl, H.3
-
133
-
-
26044473385
-
Atypical diabetes associated with inclusion formation in the R6/2 mouse model of Huntington's disease is not improved by treatment with hypoglycaemic agents
-
DOI 10.1007/s00221-005-2357-z
-
Hunt M, Morton A. Atypical diabetes associated with inclusion formation in the R6/2 mouse model of Huntington's Disease is not improved by treatment with hypoglycaemic agents. Exp Brain Res 2005;166:220-9 (Pubitemid 41406813)
-
(2005)
Experimental Brain Research
, vol.166
, Issue.2
, pp. 220-229
-
-
Hunt, M.J.1
Morton, A.J.2
-
134
-
-
70049083077
-
Therapeutic interventions for symptomatic treatment in Huntington's disease
-
Mestre T, Ferreira J, Coelho MM, et al. Therapeutic interventions for symptomatic treatment in Huntington's disease. Cochrane Database Syst Rev 2009(3):CD006456
-
(2009)
Cochrane Database Syst Rev
, Issue.3
-
-
Mestre, T.1
Ferreira, J.2
Coelho, M.M.3
-
135
-
-
70049091196
-
Therapeutic interventions for disease progression in Huntington's disease
-
Mestre T, Ferreira J, Coelho MM, et al. Therapeutic interventions for disease progression in Huntington's disease. Cochrane Database Syst Rev 2009(3):CD006455
-
(2009)
Cochrane Database Syst Rev
, Issue.3
-
-
Mestre, T.1
Ferreira, J.2
Coelho, M.M.3
-
136
-
-
37149029659
-
Diabetes, the metabolic syndrome, and ischemic stroke: Epidemiology and possible mechanisms
-
DOI 10.2337/dc06-1537
-
Air EL, Kissela BM. Diabetes, the metabolic syndrome, and ischemic stroke: epidemiology and possible mechanisms. Diabetes Care 2007;30: 3131-40 (Pubitemid 350258454)
-
(2007)
Diabetes Care
, vol.30
, Issue.12
, pp. 3131-3140
-
-
Air, E.L.1
Kissela, B.M.2
-
137
-
-
34249092704
-
Calcium and neurodegeneration
-
Mattson MP. Calcium and neurodegeneration. Aging Cell 2007;6:337-50
-
(2007)
Aging Cell
, vol.6
, pp. 337-50
-
-
Mattson, M.P.1
-
138
-
-
64649102619
-
GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice
-
Noyan-Ashraf M, Momen M, Ban K, et al. GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice. Diabetes 2009;58:975-83
-
(2009)
Diabetes
, vol.58
, pp. 975-83
-
-
Noyan-Ashraf, M.1
Momen, M.2
Ban, K.3
-
139
-
-
33846501672
-
Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy
-
DOI 10.1016/j.expneurol.2006.09.028, PII S0014488606005474
-
Perry TA, Holloway H, Weerasuriya A, et al. Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy. Exp Neurol 2007;203:293-301 (Pubitemid 46157226)
-
(2007)
Experimental Neurology
, vol.203
, Issue.2
, pp. 293-301
-
-
Perry, T.1
Holloway, H.W.2
Weerasuriya, A.3
Mouton, P.R.4
Duffy, K.5
Mattison, J.A.6
Greig, N.H.7
-
140
-
-
0842325280
-
Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells
-
DOI 10.1016/j.autneu.2003.11.001
-
Nakagawa A, Satake H, Nakabayashi H, et al. Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells. Auton Neurosci 2004;110:36-43 (Pubitemid 38180536)
-
(2004)
Autonomic Neuroscience: Basic and Clinical
, vol.110
, Issue.1
, pp. 36-43
-
-
Nakagawa, A.1
Satake, H.2
Nakabayashi, H.3
Nishizawa, M.4
Furuya, K.5
Nakano, S.6
Kigoshi, T.7
Nakayama, K.8
Uchida, K.9
-
141
-
-
0035434115
-
Glucose Competence of the Hepatoportal Vein Sensor Requires the Presence of an Activated Glucagon-Like Peptide-1 Receptor
-
Burcelin R, Da Costa A, Drucker D, et al. Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor. Diabetes 2001;50:1720-8 (Pubitemid 33641588)
-
(2001)
Diabetes
, vol.50
, Issue.8
, pp. 1720-1728
-
-
Burcelin, R.1
Da Costa, A.2
Drucker, D.3
Thorens, B.4
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