-
1
-
-
0033972493
-
Negative consequences of glycation
-
Brownlee M. Negative consequences of glycation. Metabolism 49 (2000) 9-13
-
(2000)
Metabolism
, vol.49
, pp. 9-13
-
-
Brownlee, M.1
-
2
-
-
0021864131
-
Glucagon physiology and pathophysiology in the light of new advances
-
Unger R.H. Glucagon physiology and pathophysiology in the light of new advances. Diabetologia 28 (1985) 574-578
-
(1985)
Diabetologia
, vol.28
, pp. 574-578
-
-
Unger, R.H.1
-
3
-
-
24944577486
-
Alpha cell function in health and disease: influence of glucagon-like peptide-1
-
Dunning B.E., Foley J.E., and Ahrén B. Alpha cell function in health and disease: influence of glucagon-like peptide-1. Diabetologia 48 (2005) 1700-1713
-
(2005)
Diabetologia
, vol.48
, pp. 1700-1713
-
-
Dunning, B.E.1
Foley, J.E.2
Ahrén, B.3
-
4
-
-
0019254971
-
Hormonal mechanisms in acute glucose counterregulation: the relative role of glucagon, epinephrine, norepinephrine, growth hormone, and cortisol
-
Gerich J., Cryer P., and Rizza R. Hormonal mechanisms in acute glucose counterregulation: the relative role of glucagon, epinephrine, norepinephrine, growth hormone, and cortisol. Metabolism 29 (1990) 1164-1175
-
(1990)
Metabolism
, vol.29
, pp. 1164-1175
-
-
Gerich, J.1
Cryer, P.2
Rizza, R.3
-
5
-
-
0016171846
-
Abnormal secretion of insulin and glucagon by the in vitro perfused pancreas of the genetically diabetic Chinese hamster
-
Frankel B.J., Gerich J.E., Hagura R., Fanska R.E., Gerritsen G.C., and Grodsky G.M. Abnormal secretion of insulin and glucagon by the in vitro perfused pancreas of the genetically diabetic Chinese hamster. J Clin Invest 53 (1974) 1637-1646
-
(1974)
J Clin Invest
, vol.53
, pp. 1637-1646
-
-
Frankel, B.J.1
Gerich, J.E.2
Hagura, R.3
Fanska, R.E.4
Gerritsen, G.C.5
Grodsky, G.M.6
-
6
-
-
0016256203
-
Characterization of the effects of arginine and glucose on glucagon and insulin release from the perfused rat pancreas
-
Gerich J.E., Charles M.A., and Grodsky G.M. Characterization of the effects of arginine and glucose on glucagon and insulin release from the perfused rat pancreas. J Clin Invest 54 (1974) 833-841
-
(1974)
J Clin Invest
, vol.54
, pp. 833-841
-
-
Gerich, J.E.1
Charles, M.A.2
Grodsky, G.M.3
-
7
-
-
26844556580
-
Glucose stimulates glucagon release in single rat alpha-cells by mechanisms that mirror the stimulus-secretion coupling in beta-cells
-
Olsen H.L., Theander S., Bokvist K., Buschard K., Wollheim C.B., and Gromada J. Glucose stimulates glucagon release in single rat alpha-cells by mechanisms that mirror the stimulus-secretion coupling in beta-cells. Endocrinology 146 (2005) 4861-4870
-
(2005)
Endocrinology
, vol.146
, pp. 4861-4870
-
-
Olsen, H.L.1
Theander, S.2
Bokvist, K.3
Buschard, K.4
Wollheim, C.B.5
Gromada, J.6
-
8
-
-
0033850226
-
Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells
-
Barg S., Galvanovskis J., Gopel S.O., Rorsman P., and Eliasson L. Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells. Diabetes 49 (2000) 1500-1510
-
(2000)
Diabetes
, vol.49
, pp. 1500-1510
-
-
Barg, S.1
Galvanovskis, J.2
Gopel, S.O.3
Rorsman, P.4
Eliasson, L.5
-
9
-
-
0033064018
-
Somatostatin induces hyperpolarization in pancreatic islet alpha cells by activating a G protein-gated K+ channel
-
Yoshimoto Y., Fukuyama Y., Horio Y., Inanobe A., Gotoh M., and Kurachi Y. Somatostatin induces hyperpolarization in pancreatic islet alpha cells by activating a G protein-gated K+ channel. FEBS Lett 444 (1999) 265-269
-
(1999)
FEBS Lett
, vol.444
, pp. 265-269
-
-
Yoshimoto, Y.1
Fukuyama, Y.2
Horio, Y.3
Inanobe, A.4
Gotoh, M.5
Kurachi, Y.6
-
10
-
-
0030967933
-
Adrenaline stimulates glucagon secretion in pancreatic A-cells by increasing the Ca2+ current and the number of granules close to the L-type Ca2+ channels
-
Gromada J., Bokvist K., Ding W.G., Barg S., Buschard K., Renstrom E., et al. Adrenaline stimulates glucagon secretion in pancreatic A-cells by increasing the Ca2+ current and the number of granules close to the L-type Ca2+ channels. J Gen Physiol 110 (1997) 217-228
-
(1997)
J Gen Physiol
, vol.110
, pp. 217-228
-
-
Gromada, J.1
Bokvist, K.2
Ding, W.G.3
Barg, S.4
Buschard, K.5
Renstrom, E.6
-
11
-
-
0027525114
-
Sulfonylurea-binding sites and ATP-sensitive K+ channels in alpha-TC glucagonoma and beta-TC insulinoma cells
-
Ronner P., Matschinsky F.M., Hang T.L., Epstein A.J., and Buettger C. Sulfonylurea-binding sites and ATP-sensitive K+ channels in alpha-TC glucagonoma and beta-TC insulinoma cells. Diabetes 42 (1993) 1760-1772
-
(1993)
Diabetes
, vol.42
, pp. 1760-1772
-
-
Ronner, P.1
Matschinsky, F.M.2
Hang, T.L.3
Epstein, A.J.4
Buettger, C.5
-
12
-
-
9444266572
-
ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells
-
Gromada J., Ma X., Hoy M., Bokvist K., Salehi A., Berggren P.O., et al. ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells. Diabetes 53 Suppl 3 (2004) S181-S189
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 3
-
-
Gromada, J.1
Ma, X.2
Hoy, M.3
Bokvist, K.4
Salehi, A.5
Berggren, P.O.6
-
13
-
-
34249778678
-
Targeting of KV4, CaV1. 2 and SNARE proteins to cholesterolrich lipid rafts in pancreatic alpha-cells:effects on glucagon stimulus-secretion coupling
-
Xia F., Leung Y.M., Gaisano G., Gao X., Chen Y., Manning Fox J.E., et al. Targeting of KV4, CaV1. 2 and SNARE proteins to cholesterolrich lipid rafts in pancreatic alpha-cells:effects on glucagon stimulus-secretion coupling. Endocrinology 148 (2007) 2157-2167
-
(2007)
Endocrinology
, vol.148
, pp. 2157-2167
-
-
Xia, F.1
Leung, Y.M.2
Gaisano, G.3
Gao, X.4
Chen, Y.5
Manning Fox, J.E.6
-
14
-
-
0022919221
-
Innervation of the canine pancreas after vagotomy
-
Radke R., and Stach W. Innervation of the canine pancreas after vagotomy. Acta Anat (Basel) 127 (1986) 88-92
-
(1986)
Acta Anat (Basel)
, vol.127
, pp. 88-92
-
-
Radke, R.1
Stach, W.2
-
16
-
-
0017226110
-
Glucagon secretion from the perfused pancreas of streptozotocintreated rats
-
Weir G.C., Knowlton S.D., Atkins R.F., McKennan K.X., and Martin D.B. Glucagon secretion from the perfused pancreas of streptozotocintreated rats. Diabetes 25 (1976) 275-282
-
(1976)
Diabetes
, vol.25
, pp. 275-282
-
-
Weir, G.C.1
Knowlton, S.D.2
Atkins, R.F.3
McKennan, K.X.4
Martin, D.B.5
-
17
-
-
0019918172
-
New perspectives on the microvasculature of the islets of Langerhans in the rat
-
Bonner-Weir S., and Orci L. New perspectives on the microvasculature of the islets of Langerhans in the rat. Diabetes 31 (1982) 883-889
-
(1982)
Diabetes
, vol.31
, pp. 883-889
-
-
Bonner-Weir, S.1
Orci, L.2
-
18
-
-
0022448477
-
Retrograde perfusion as a model for testing the relative effects of glucose versus insulin on the cell
-
Stagner J.I., and Samols E. Retrograde perfusion as a model for testing the relative effects of glucose versus insulin on the cell. J Clin Invest 77 (1986) 1034-1037
-
(1986)
J Clin Invest
, vol.77
, pp. 1034-1037
-
-
Stagner, J.I.1
Samols, E.2
-
19
-
-
0020505255
-
insulin glucagon relationship in the defense against hypoglycaemia
-
Unger R. insulin glucagon relationship in the defense against hypoglycaemia. Diabetes 32 (1983) 575-583
-
(1983)
Diabetes
, vol.32
, pp. 575-583
-
-
Unger, R.1
-
20
-
-
25844492048
-
Glucose-regulated glucagon secretion requires insulin receptor expression in pancreatic alpha-cells
-
Diao J., Asghar Z., Chan C.B., and Wheeler M.B. Glucose-regulated glucagon secretion requires insulin receptor expression in pancreatic alpha-cells. J Biol Chem 280 (2005) 33487-33496
-
(2005)
J Biol Chem
, vol.280
, pp. 33487-33496
-
-
Diao, J.1
Asghar, Z.2
Chan, C.B.3
Wheeler, M.B.4
-
21
-
-
34047099750
-
Zinc, not insulin, regulates the rat alpha cell response to hypoglycaemia in vivo
-
Zhou H., Zhang T., Harmon J.S., Bryan J., and Robertson R.P. Zinc, not insulin, regulates the rat alpha cell response to hypoglycaemia in vivo. Diabetes 56 (2007) 1107-1112
-
(2007)
Diabetes
, vol.56
, pp. 1107-1112
-
-
Zhou, H.1
Zhang, T.2
Harmon, J.S.3
Bryan, J.4
Robertson, R.P.5
-
22
-
-
0034986053
-
Evidence that extrapancreatic GLUT2-dependent glucose sensors control glucagon secretion
-
Burcelin R., and Thorens B. Evidence that extrapancreatic GLUT2-dependent glucose sensors control glucagon secretion. Diabetes 50 (2001) 1282-1289
-
(2001)
Diabetes
, vol.50
, pp. 1282-1289
-
-
Burcelin, R.1
Thorens, B.2
-
23
-
-
0025945011
-
Structural and functional considerations of GABA in islets of Langerhans. Beta-cells and nerves
-
Sorenson R.L., Garry D.G., and Brelje T.C. Structural and functional considerations of GABA in islets of Langerhans. Beta-cells and nerves. Diabetes 40 (1991) 1365-1374
-
(1991)
Diabetes
, vol.40
, pp. 1365-1374
-
-
Sorenson, R.L.1
Garry, D.G.2
Brelje, T.C.3
-
24
-
-
0034001450
-
Autonomic regulation of islet hormone secretion--implications for health and disease
-
Ahrén B. Autonomic regulation of islet hormone secretion--implications for health and disease. Diabetologia 43 (2000) 393-410
-
(2000)
Diabetologia
, vol.43
, pp. 393-410
-
-
Ahrén, B.1
-
25
-
-
0035157768
-
Glucose sensing in pancreatic beta-cells: a model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus
-
Schuit F.C., Huypens P., Heimberg H., and Pipeleers D.G. Glucose sensing in pancreatic beta-cells: a model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus. Diabetes 50 (2001) 1-11
-
(2001)
Diabetes
, vol.50
, pp. 1-11
-
-
Schuit, F.C.1
Huypens, P.2
Heimberg, H.3
Pipeleers, D.G.4
-
26
-
-
0022638433
-
Differences in adrenergic recognition by pancreatic A and B cells
-
Schuit F.C., and Pipeleers D.G. Differences in adrenergic recognition by pancreatic A and B cells. Science 232 (1986) 875-877
-
(1986)
Science
, vol.232
, pp. 875-877
-
-
Schuit, F.C.1
Pipeleers, D.G.2
-
27
-
-
17844375114
-
Parasympathetic innervation and function of endocrine pancreas requires the glial cell line-derived factor family receptor alpha2 (GFRalpha2)
-
Rossi J., Santamaki P., Airaksinen M.S., and Herzig K.H. Parasympathetic innervation and function of endocrine pancreas requires the glial cell line-derived factor family receptor alpha2 (GFRalpha2). Diabetes 54 (2005) 1324-1330
-
(2005)
Diabetes
, vol.54
, pp. 1324-1330
-
-
Rossi, J.1
Santamaki, P.2
Airaksinen, M.S.3
Herzig, K.H.4
-
28
-
-
33846856711
-
Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains
-
Gromada J., Franklin I., and Wollheim C.B. Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains. Endocr Rev 28 (2007) 84-116
-
(2007)
Endocr Rev
, vol.28
, pp. 84-116
-
-
Gromada, J.1
Franklin, I.2
Wollheim, C.B.3
-
29
-
-
12244261646
-
GLP-1 and extra-islet effects
-
Ahrén B. GLP-1 and extra-islet effects. Horm Metab Res 36 (2004) 842-845
-
(2004)
Horm Metab Res
, vol.36
, pp. 842-845
-
-
Ahrén, B.1
-
30
-
-
0029954211
-
Glucagonostatic actions and reduction of fasting hyperglycaemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients
-
Creutzfeldt W.O., Kleine N., Willms B., Orskov C., Holst J.J., and Nauck M.A. Glucagonostatic actions and reduction of fasting hyperglycaemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients. Diabetes Care 19 (1996) 580-586
-
(1996)
Diabetes Care
, vol.19
, pp. 580-586
-
-
Creutzfeldt, W.O.1
Kleine, N.2
Willms, B.3
Orskov, C.4
Holst, J.J.5
Nauck, M.A.6
-
31
-
-
1842598583
-
Glucagon-like peptide 1 improved glycaemic control in type 1 diabetes
-
Behme M.T., Dupré J., and McDonald T.J. Glucagon-like peptide 1 improved glycaemic control in type 1 diabetes. BMC Endocr Disord 3 (2003) 3
-
(2003)
BMC Endocr Disord
, vol.3
, pp. 3
-
-
Behme, M.T.1
Dupré, J.2
McDonald, T.J.3
-
32
-
-
20044374696
-
Betacell secretory products activate alpha-cell ATP-dependent potassium channels to inhibit glucagon release
-
Franklin I., Gromada J., Gjinovci A., Theander S., and Wollheim C.B. Betacell secretory products activate alpha-cell ATP-dependent potassium channels to inhibit glucagon release. Diabetes 54 (2005) 1808-1815
-
(2005)
Diabetes
, vol.54
, pp. 1808-1815
-
-
Franklin, I.1
Gromada, J.2
Gjinovci, A.3
Theander, S.4
Wollheim, C.B.5
-
33
-
-
0030975613
-
Insulinotropic glucagon-like peptide I receptor expression in glucagon-producing alpha-cells of the rat endocrine pancreas
-
Heller R.S., Kieffer T.J., and Habener J.F. Insulinotropic glucagon-like peptide I receptor expression in glucagon-producing alpha-cells of the rat endocrine pancreas. Diabetes 46 (1997) 785-791
-
(1997)
Diabetes
, vol.46
, pp. 785-791
-
-
Heller, R.S.1
Kieffer, T.J.2
Habener, J.F.3
-
34
-
-
0030943464
-
Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+ -induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism
-
Ding W.G., Renstrom E., Rorsman P., Buschard K., and Gromada J. Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+ -induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism. Diabetes 46 (1997) 792-800
-
(1997)
Diabetes
, vol.46
, pp. 792-800
-
-
Ding, W.G.1
Renstrom, E.2
Rorsman, P.3
Buschard, K.4
Gromada, J.5
-
35
-
-
31044456099
-
Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage
-
Knauf C., Cani P., Perrin C., Iglesias M., Maury J., Bernard E., et al. Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage. J Clin Invest 115 (2005) 3554-3563
-
(2005)
J Clin Invest
, vol.115
, pp. 3554-3563
-
-
Knauf, C.1
Cani, P.2
Perrin, C.3
Iglesias, M.4
Maury, J.5
Bernard, E.6
-
36
-
-
11144357764
-
Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors
-
Preitner F., Ibberson M., Franklin I., Binnert C., Pende M., Gjinovci A., et al. Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors. J Clin Invest 113 (2004) 635-645
-
(2004)
J Clin Invest
, vol.113
, pp. 635-645
-
-
Preitner, F.1
Ibberson, M.2
Franklin, I.3
Binnert, C.4
Pende, M.5
Gjinovci, A.6
-
37
-
-
0029829821
-
Vagal hepatopancreatic reflex effect evoked by intraportal appearance of tGLP-1
-
Nakabayashi H., Nishizawa M., Nakagawa A., Takeda R., and Niijima A. Vagal hepatopancreatic reflex effect evoked by intraportal appearance of tGLP-1. Am J Physiol 271 (1996) E808-E813
-
(1996)
Am J Physiol
, vol.271
-
-
Nakabayashi, H.1
Nishizawa, M.2
Nakagawa, A.3
Takeda, R.4
Niijima, A.5
-
38
-
-
23044432669
-
The incretins: a link between nutrients and well-being
-
Burcelin R. The incretins: a link between nutrients and well-being. Br J Nutr 93 Suppl 1 (2005) S147-S156
-
(2005)
Br J Nutr
, vol.93
, Issue.SUPPL. 1
-
-
Burcelin, R.1
-
39
-
-
0035434115
-
Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor
-
Burcelin R., Da Costa A., Drucker D., and Thorens B. Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor. Diabetes 50 (2001) 1720-1728
-
(2001)
Diabetes
, vol.50
, pp. 1720-1728
-
-
Burcelin, R.1
Da Costa, A.2
Drucker, D.3
Thorens, B.4
-
40
-
-
2642593026
-
Autonomic mediation of glucagon secretion during hypoglycaemia: implications for impaired alphacell responses in type 1 diabetes
-
Taborsky G.J., Ahrén B., and Havel P.J. Autonomic mediation of glucagon secretion during hypoglycaemia: implications for impaired alphacell responses in type 1 diabetes. Diabetes 47 (1998) 995-1005
-
(1998)
Diabetes
, vol.47
, pp. 995-1005
-
-
Taborsky, G.J.1
Ahrén, B.2
Havel, P.J.3
-
41
-
-
0015901935
-
Lack of glucagon response to hypoglycaemia in diabetes: evidence for an intrinsic pancreatic alpha cell defect
-
Gerich J.E., Langlois M., Noacco C., Karam J.H., and Forsham P.H. Lack of glucagon response to hypoglycaemia in diabetes: evidence for an intrinsic pancreatic alpha cell defect. Science 182 (1973) 171-173
-
(1973)
Science
, vol.182
, pp. 171-173
-
-
Gerich, J.E.1
Langlois, M.2
Noacco, C.3
Karam, J.H.4
Forsham, P.H.5
-
42
-
-
0029937016
-
Glucagon response to hypoglycaemia is improved by insulin-independent restoration of normoglycaemia in diabetic rats
-
Shi Z.Q., Rastogi K.S., Lekas M., Efendic S., Drucker D.J., and Vranic M. Glucagon response to hypoglycaemia is improved by insulin-independent restoration of normoglycaemia in diabetic rats. Endocrinology 137 (1996) 3193-3199
-
(1996)
Endocrinology
, vol.137
, pp. 3193-3199
-
-
Shi, Z.Q.1
Rastogi, K.S.2
Lekas, M.3
Efendic, S.4
Drucker, D.J.5
Vranic, M.6
-
43
-
-
0023855186
-
Correlation between minimal secretory capacity of pancreatic beta-cells and stability of diabetic control
-
Fukuda M., Tanaka A., Tahara Y., Ikegami H., Yamamoto Y., Kumahara Y., et al. Correlation between minimal secretory capacity of pancreatic beta-cells and stability of diabetic control. Diabetes 37 (1988) 81-88
-
(1988)
Diabetes
, vol.37
, pp. 81-88
-
-
Fukuda, M.1
Tanaka, A.2
Tahara, Y.3
Ikegami, H.4
Yamamoto, Y.5
Kumahara, Y.6
-
44
-
-
0018130888
-
Effect of insulin therapy on the profiles of plasma immunoreactive glucagon in juvenile-type and adult-type diabetics
-
Raskin P., and Unger R.H. Effect of insulin therapy on the profiles of plasma immunoreactive glucagon in juvenile-type and adult-type diabetics. Diabetes 27 (1978) 411-419
-
(1978)
Diabetes
, vol.27
, pp. 411-419
-
-
Raskin, P.1
Unger, R.H.2
-
45
-
-
0021677838
-
Plasma glucagon suppressibility after oral glucose in obese subjects with normal and impaired glucose tolerance
-
Borghi V.C., Wajchenberg B.L., and Cesar F.P. Plasma glucagon suppressibility after oral glucose in obese subjects with normal and impaired glucose tolerance. Metabolism 33 (1984) 1068-1074
-
(1984)
Metabolism
, vol.33
, pp. 1068-1074
-
-
Borghi, V.C.1
Wajchenberg, B.L.2
Cesar, F.P.3
-
46
-
-
0023109225
-
Documentation of hyperglucagonaemia throughout the day in nonobese and obese patients with noninsulin-dependent diabetes mellitus
-
Reaven G.M., Chen Y.D., Golay A., Swislocki A.L., and Jaspan J.B. Documentation of hyperglucagonaemia throughout the day in nonobese and obese patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 64 (1987) 106-110
-
(1987)
J Clin Endocrinol Metab
, vol.64
, pp. 106-110
-
-
Reaven, G.M.1
Chen, Y.D.2
Golay, A.3
Swislocki, A.L.4
Jaspan, J.B.5
-
47
-
-
0026000359
-
Abnormal glucagon response to arginine and its normalization in obese hyperinsulinaemic patients with glucose intolerance: importance of insulin action on pancreatic alpha cells
-
Hamaguchi T., Fukushima H., Uehara M., Wada S., Shirotani T., Kishikawa H., et al. Abnormal glucagon response to arginine and its normalization in obese hyperinsulinaemic patients with glucose intolerance: importance of insulin action on pancreatic alpha cells. Diabetologia 34 (1991) 801-806
-
(1991)
Diabetologia
, vol.34
, pp. 801-806
-
-
Hamaguchi, T.1
Fukushima, H.2
Uehara, M.3
Wada, S.4
Shirotani, T.5
Kishikawa, H.6
-
48
-
-
0033890616
-
-
Gastaldelli A, Baldi S, Pettiti M, Toschi E, Camastra S, Natali A, et al. Influence of obesity and type 2 diabetes on gluconeogenesis and glucose output in humans: a quantitative study. Diabetes 200;49:1367-73.
-
Gastaldelli A, Baldi S, Pettiti M, Toschi E, Camastra S, Natali A, et al. Influence of obesity and type 2 diabetes on gluconeogenesis and glucose output in humans: a quantitative study. Diabetes 200;49:1367-73.
-
-
-
-
50
-
-
0017641399
-
Immunoreactive glucagon (IRG) responses to intravenous glucose in prediabetes and diabetes among Pima Indians and normal Caucasians
-
Aronoff S.L., Bennett P.H., and Unger R.H. Immunoreactive glucagon (IRG) responses to intravenous glucose in prediabetes and diabetes among Pima Indians and normal Caucasians. J Clin Endocrinol Metab 44 (1977) 968-972
-
(1977)
J Clin Endocrinol Metab
, vol.44
, pp. 968-972
-
-
Aronoff, S.L.1
Bennett, P.H.2
Unger, R.H.3
-
51
-
-
0014951784
-
Abnormal alpha-cell function in diabetes. Response to carbohydrate and protein ingestion
-
Muller W.A., Faloona G.R., Aguilar-Parada E., and Unger R.H. Abnormal alpha-cell function in diabetes. Response to carbohydrate and protein ingestion. N Engl J Med 283 (1970) 109-115
-
(1970)
N Engl J Med
, vol.283
, pp. 109-115
-
-
Muller, W.A.1
Faloona, G.R.2
Aguilar-Parada, E.3
Unger, R.H.4
-
52
-
-
0018194884
-
Abnormal alpha cell function in human diabetes: the response to oral protein
-
Raskin P., Aydin I., Yamamoto T., and Unger R.H. Abnormal alpha cell function in human diabetes: the response to oral protein. Am J Med 64 (1978) 988-997
-
(1978)
Am J Med
, vol.64
, pp. 988-997
-
-
Raskin, P.1
Aydin, I.2
Yamamoto, T.3
Unger, R.H.4
-
53
-
-
0021751981
-
Diminished cell secretory capacity in patients with noninsulin-dependent diabetes mellitus
-
Ward W.K., Bolgiano D.C., McKnight B., Halter J.B., and Porte Jr. D. Diminished cell secretory capacity in patients with noninsulin-dependent diabetes mellitus. J Clin Invest 74 (1984) 1318-1328
-
(1984)
J Clin Invest
, vol.74
, pp. 1318-1328
-
-
Ward, W.K.1
Bolgiano, D.C.2
McKnight, B.3
Halter, J.B.4
Porte Jr., D.5
-
54
-
-
0024511329
-
Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM
-
Consoli A., Nurjhan N., Capani F., and Gerich J. Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM. Diabetes 38 (1989) 550-557
-
(1989)
Diabetes
, vol.38
, pp. 550-557
-
-
Consoli, A.1
Nurjhan, N.2
Capani, F.3
Gerich, J.4
-
55
-
-
3042701667
-
Both fasting glucose production and disappearance are abnormal in people with "mild" and "severe" type 2 diabetes
-
Basu R., Schwenk W.F., and Rizza R.A. Both fasting glucose production and disappearance are abnormal in people with "mild" and "severe" type 2 diabetes. Am J Physiol Endocrinol Metab 287 (2004) E55-E62
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
-
-
Basu, R.1
Schwenk, W.F.2
Rizza, R.A.3
-
56
-
-
0023589251
-
Role of hyperglucagonaemia in maintenance of increased rates of hepatic glucose output in type II diabetics
-
Baron A.D., Schaeffer L., Shragg P., and Kolterman O.G. Role of hyperglucagonaemia in maintenance of increased rates of hepatic glucose output in type II diabetics. Diabetes 36 (1987) 274-283
-
(1987)
Diabetes
, vol.36
, pp. 274-283
-
-
Baron, A.D.1
Schaeffer, L.2
Shragg, P.3
Kolterman, O.G.4
-
57
-
-
0036296165
-
Glycaemic control in mice with targeted disruption of the glucagon receptor gene
-
Parker J.C., Andrews K.M., Allen M.R., Stock J.L., and McNeish J.D. Glycaemic control in mice with targeted disruption of the glucagon receptor gene. Biochem Biophys Res Commun 290 (2002) 839-843
-
(2002)
Biochem Biophys Res Commun
, vol.290
, pp. 839-843
-
-
Parker, J.C.1
Andrews, K.M.2
Allen, M.R.3
Stock, J.L.4
McNeish, J.D.5
-
58
-
-
0033663923
-
Effects of skyrin, a receptor-selective glucagon antagonist, in rat and human hepatocytes
-
Parker J.C., McPherson R.K., Andrews K.M., Levy C.B., Dubins J.S., Chin J.E., et al. Effects of skyrin, a receptor-selective glucagon antagonist, in rat and human hepatocytes. Diabetes 49 (2000) 2079-2086
-
(2000)
Diabetes
, vol.49
, pp. 2079-2086
-
-
Parker, J.C.1
McPherson, R.K.2
Andrews, K.M.3
Levy, C.B.4
Dubins, J.S.5
Chin, J.E.6
-
59
-
-
0022892617
-
Design and synthesis of glucagon partial agonists and antagonists
-
Gysin B., Trivedi D., Johnson D.G., and Hruby V.J. Design and synthesis of glucagon partial agonists and antagonists. Biochemistry 25 (1986) 8278-8284
-
(1986)
Biochemistry
, vol.25
, pp. 8278-8284
-
-
Gysin, B.1
Trivedi, D.2
Johnson, D.G.3
Hruby, V.J.4
-
60
-
-
0032542247
-
Discovery and structure-activity relationship of the first non-peptide competitive human glucagon receptor antagonists
-
Madsen P., Knudsen L.B., Wiberg F.C., and Carr R.D. Discovery and structure-activity relationship of the first non-peptide competitive human glucagon receptor antagonists. J Med Chem 41 (1998) 5150-5157
-
(1998)
J Med Chem
, vol.41
, pp. 5150-5157
-
-
Madsen, P.1
Knudsen, L.B.2
Wiberg, F.C.3
Carr, R.D.4
-
61
-
-
33845919110
-
Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia
-
Conarello S.L., Jiang G., Mu J., Li Z., Woods J., Zycband E., et al. Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia. Diabetologia 50 (2007) 142-150
-
(2007)
Diabetologia
, vol.50
, pp. 142-150
-
-
Conarello, S.L.1
Jiang, G.2
Mu, J.3
Li, Z.4
Woods, J.5
Zycband, E.6
-
62
-
-
0037417984
-
Lower blood glucose, hyperglucagonaemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice
-
Gelling R.W., Du X.Q., Dichmann D.S., Romer J., Huang H., Cui L., et al. Lower blood glucose, hyperglucagonaemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice. Proc Natl Acad Sci U S A 100 (2003) 1438-1443
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 1438-1443
-
-
Gelling, R.W.1
Du, X.Q.2
Dichmann, D.S.3
Romer, J.4
Huang, H.5
Cui, L.6
-
63
-
-
33747615019
-
Ablation of the glucagon receptor gene increases fetal lethality and produces alterations in islet development and maturation
-
Vuguin P.M., Kedees M.H., Cui L., Guz Y., Gelling R.W., Nejathaim M., et al. Ablation of the glucagon receptor gene increases fetal lethality and produces alterations in islet development and maturation. Endocrinology 147 (2006) 3995-4006
-
(2006)
Endocrinology
, vol.147
, pp. 3995-4006
-
-
Vuguin, P.M.1
Kedees, M.H.2
Cui, L.3
Guz, Y.4
Gelling, R.W.5
Nejathaim, M.6
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