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Volumn 6, Issue , 2011, Pages 121-145

Disorders of bone remodeling

Author keywords

osteopetrosis; osteoporosis; Paget's disease; renal osteodystrophy; rickets

Indexed keywords

PARATHYROID HORMONE; REACTIVE OXYGEN METABOLITE;

EID: 79751499788     PISSN: 15534006     EISSN: 15534014     Source Type: Book Series    
DOI: 10.1146/annurev-pathol-011110-130203     Document Type: Article
Times cited : (960)

References (157)
  • 3
    • 0028362416 scopus 로고
    • Osteonal and Hemi-Osteonal remodeling: The spatial and temporal framework for signal traffic in adult human bone
    • DOI 10.1002/jcb.240550303
    • Parfitt AM. 1994. Osteonal and hemi-osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone. J. Cell Biochem. 55:273-86 (Pubitemid 24218802)
    • (1994) Journal of Cellular Biochemistry , vol.55 , Issue.3 , pp. 273-286
    • Parfitt, A.M.1
  • 5
    • 0034874481 scopus 로고    scopus 로고
    • Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markers
    • Hauge EM, Qvesel D, Eriksen EF, Mosekilde L, Melsen F. 2001. Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblasticmarkers. J. Bone Miner. Res. 16:1575-82 (Pubitemid 32786425)
    • (2001) Journal of Bone and Mineral Research , vol.16 , Issue.9 , pp. 1575-1582
    • Hauge, E.M.1    Qvesel, D.2    Eriksen, E.F.3    Mosekilde, L.4    Melsen, F.5
  • 6
    • 0034873321 scopus 로고    scopus 로고
    • The bone remodeling compartment: A circulatory function for bone lining cells
    • Parfitt AM. 2001. The bone remodeling compartment: a circulatory function for bone lining cells. J. Bone Miner. Res. 16:1583-85 (Pubitemid 32786426)
    • (2001) Journal of Bone and Mineral Research , vol.16 , Issue.9 , pp. 1583-1585
    • Parfitt, A.M.1
  • 7
    • 37249057821 scopus 로고    scopus 로고
    • Osteocytes as dynamic multifunctional cells
    • DOI 10.1196/annals.1402.018, Skeletal Biology and Medicine, Part A: Aspects of Bone Morphogenesis and Remodeling
    • Bonewald LF. 2007. Osteocytes as dynamic multifunctional cells. Ann. N.Y. Acad. Sci. 1116:281-90 (Pubitemid 350274320)
    • (2007) Annals of the New York Academy of Sciences , vol.1116 , pp. 281-290
    • Bonewald, L.F.1
  • 8
    • 67349109815 scopus 로고    scopus 로고
    • The role of osteocytes in bone mechanotransduction
    • Santos A, Bakker AD, Klein-Nulend J. 2009. The role of osteocytes in bone mechanotransduction. Osteoporos. Int. 20:1027-31
    • (2009) Osteoporos. Int. , vol.20 , pp. 1027-1031
    • Santos, A.1    Bakker, A.D.2    Klein-Nulend, J.3
  • 9
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • Teitelbaum SL. 2000. Bone resorption by osteoclasts. Science 289:1504-8
    • (2000) Science , vol.289 , pp. 1504-1508
    • Teitelbaum, S.L.1
  • 10
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • DOI 10.1038/nature01658
    • Boyle WJ, Simonet WS, Lacey DL. 2003. Osteoclast differentiation and activation. Nature 423:337-42 (Pubitemid 40852708)
    • (2003) Nature , vol.423 , Issue.6937 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 11
    • 1842493783 scopus 로고    scopus 로고
    • Osteoclast biology
    • ed. R Marcus, D Feldman, J Kelsey, San Diego: Academic
    • Ross FP, Teitelbaum SL. 2001. Osteoclast biology. In Osteoporosis, ed. R Marcus, D Feldman, J Kelsey, pp. 73-106. San Diego: Academic
    • (2001) Osteoporosis , pp. 73-106
    • Ross, F.P.1    Teitelbaum, S.L.2
  • 12
    • 0034285013 scopus 로고    scopus 로고
    • The osteoblast: A sophisticated fibroblast under central surveillance
    • Ducy P, Schinke T, Karsenty G. 2000. The osteoblast: a sophisticated fibroblast under central surveillance. Science 289:1501-4
    • (2000) Science , vol.289 , pp. 1501-1504
    • Ducy, P.1    Schinke, T.2    Karsenty, G.3
  • 15
    • 38649092398 scopus 로고    scopus 로고
    • Skeletal stem/osteoprogenitor cells: Current concepts, alternate hypotheses, and relationship to the bone remodeling compartment
    • DOI 10.1002/jcb.21423
    • Modder UI, Khosla S. 2008. Skeletal stem/osteoprogenitor cells: current concepts, alternate hypotheses, and relationship to the bone remodeling compartment. J. Cell Biochem. 103:393-400 (Pubitemid 351171911)
    • (2008) Journal of Cellular Biochemistry , vol.103 , Issue.2 , pp. 393-400
    • Modder, U.I.1    Khosla, S.2
  • 16
    • 84884072880 scopus 로고    scopus 로고
    • Skeletal heterogeneity and the purposes of bone remodeling: Implications for the understanding of osteoporosis
    • ed. R Marcus, D Feldman, DA Nelson, CJ Rosen, San Diego: Elsevier
    • Parfitt AM. 2008. Skeletal heterogeneity and the purposes of bone remodeling: implications for the understanding of osteoporosis. In Osteoporosis, ed. RMarcus, D Feldman, DA Nelson, CJ Rosen, pp. 71-92. San Diego: Elsevier
    • (2008) Osteoporosis , pp. 71-92
    • Parfitt, A.M.1
  • 17
    • 33846332080 scopus 로고    scopus 로고
    • New mechanisms and targets in the treatment of bone fragility
    • DOI 10.1042/CS20060046
    • Martin TJ, Seeman E. 2007. New mechanisms and targets in the treatment of bone fragility. Clin. Sci. (Lond.) 112:77-91 (Pubitemid 46120088)
    • (2007) Clinical Science , vol.112 , Issue.1-2 , pp. 77-91
    • Martin, T.J.1    Seeman, E.2
  • 18
    • 0036140080 scopus 로고    scopus 로고
    • Targeted and nontargeted bone remodeling: Relationship to basic multicellular unit origination and progression
    • DOI 10.1016/S8756-3282(01)00642-1, PII S8756328201006421
    • Parfitt AM. 2002. Targeted and nontargeted bone remodeling: relationship to basic multicellular unit origination and progression. Bone 30:5-7 (Pubitemid 34044294)
    • (2002) Bone , vol.30 , Issue.1 , pp. 5-7
    • Parfitt, A.M.1
  • 20
    • 0024194993 scopus 로고
    • Hormonal regulation of bone growth and remodelling
    • Raisz LG. 1988. Hormonal regulation of bone growth and remodelling. Ciba Found. Symp. 136:226-38
    • (1988) Ciba Found. Symp. , vol.136 , pp. 226-238
    • Raisz, L.G.1
  • 21
    • 0029974428 scopus 로고    scopus 로고
    • Insulin-like growth factor system components and the coupling of bone formation to resorption
    • Mohan S, Baylink DJ. 1996. Insulin-like growth factor system components and the coupling of bone formation to resorption. Horm. Res. 45(Suppl. 1):59-62 (Pubitemid 26188661)
    • (1996) Hormone Research , vol.45 , Issue.SUPPL. 1 , pp. 59-62
    • Mohan, S.1    Baylink, D.J.2
  • 22
    • 0025930116 scopus 로고
    • The effects of TGF-âon bone
    • Mundy GR. 1991. The effects of TGF-âon bone. Ciba Found. Symp. 157:137-43
    • (1991) Ciba Found. Symp. , vol.157 , pp. 137-143
    • Mundy, G.R.1
  • 23
    • 67650506105 scopus 로고    scopus 로고
    • TGF-â1-induced migration of bone mesenchymal stem cells couples bone resorption with formation
    • Tang Y, Wu X, LeiW, Pang L,Wan C, et al. 2009. TGF-â1-induced migration of bone mesenchymal stem cells couples bone resorption with formation. Nat. Med. 15:757-65
    • (2009) Nat. Med. , vol.15 , pp. 757-765
    • Tang, Y.1    Wu, X.2    Lei, W.3    Pang, L.4    Wan, C.5
  • 25
    • 58849164046 scopus 로고    scopus 로고
    • Molecular mechanisms in coupling of bone formation to resorption
    • Martin T, Gooi JH, Sims NA. 2009. Molecular mechanisms in coupling of bone formation to resorption. Crit. Rev. Eukaryot. Gene Expr. 19:73-88
    • (2009) Crit. Rev. Eukaryot. Gene Expr. , vol.19 , pp. 73-88
    • Martin, T.1    Gooi, J.H.2    Sims, N.A.3
  • 26
    • 42749088910 scopus 로고    scopus 로고
    • Osteoclast-osteoblast communication
    • Matsuo K, Irie N. 2008. Osteoclast-osteoblast communication. Arch. Biochem. Biophys. 473:201-9
    • (2008) Arch. Biochem. Biophys. , vol.473 , pp. 201-209
    • Matsuo, K.1    Irie, N.2
  • 27
    • 75149120560 scopus 로고    scopus 로고
    • Myeloma cell-induced disruption of bone remodelling compartments leads to osteolytic lesions and generation of osteoclast-myeloma hybrid cells
    • Andersen TL, Soe K, Sondergaard TE, Plesner T, Delaisse JM. 2009. Myeloma cell-induced disruption of bone remodelling compartments leads to osteolytic lesions and generation of osteoclast-myeloma hybrid cells. Br. J. Haematol. 48:551-61
    • (2009) Br. J. Haematol. , vol.48 , pp. 551-561
    • Andersen, T.L.1    Soe, K.2    Sondergaard, T.E.3    Plesner, T.4    Delaisse, J.M.5
  • 28
    • 0035857351 scopus 로고    scopus 로고
    • Osteoporosis prevention, diagnosis, and therapy
    • Natl. Inst. Health Consens. Dev. Panel
    • Natl. Inst. Health Consens. Dev. Panel. 2001. Osteoporosis prevention, diagnosis, and therapy. J. Am. Med. Assoc. 285:785-95
    • (2001) J. Am. Med. Assoc. , vol.285 , pp. 785-795
  • 29
    • 84883934672 scopus 로고    scopus 로고
    • The nature of osteoporosis
    • ed. R Marcus, D Feldman, DA Nelson, CJ Rosen, San Diego: Academic
    • Marcus R, Bouxsein M. 2008. The nature of osteoporosis. In Osteoporosis, ed. R Marcus, D Feldman, DA Nelson, CJ Rosen, pp. 27-36. San Diego: Academic
    • (2008) Osteoporosis , pp. 27-36
    • Marcus, R.1    Bouxsein, M.2
  • 30
    • 0019942628 scopus 로고
    • Changes in bone mineral density of the proximal femur and spine with aging. Differences between the postmenopausal and senile osteoporosis syndromes
    • Riggs BL, Wahner HW, Seeman E, Offord KP, Dunn WL, et al. 1982. Changes in bone mineral density of the proximal femur and spine with aging. Differences between the postmenopausal and senile osteoporosis syndromes. J. Clin. Investig. 70:716-23 (Pubitemid 12038087)
    • (1982) Journal of Clinical Investigation , vol.70 , Issue.4 , pp. 716-723
    • Riggs, B.L.1    Wahner, H.W.2    Seeman, E.3
  • 31
    • 0043017070 scopus 로고    scopus 로고
    • The type I/type II model for involutional osteoporosis
    • ed. R Marcus, D Feldman, J Kelsey, San Diego: Academic
    • Riggs BL, Khosla S, Melton LJ. 2001. The type I/type II model for involutional osteoporosis. In Osteoporosis, ed. R Marcus, D Feldman, J Kelsey, pp. 49-58. San Diego: Academic
    • (2001) Osteoporosis , pp. 49-58
    • Riggs, B.L.1    Khosla, S.2    Melton, L.J.3
  • 34
    • 0025100436 scopus 로고
    • Cancellous bone remodeling in type I (postmenopausal) osteoporosis: Quantitative assessment of rates of formation, resorption, and bone loss at tissue and cellular levels
    • Eriksen EF, Hodgson SF, Eastell R, Cedel SL, O'FallonWM, Riggs BL. 1990. Cancellous bone remodeling in type I (postmenopausal) osteoporosis: quantitative assessment of rates of formation, resorption, and bone loss at tissue and cellular levels. J. Bone Miner. Res. 5:311-9 (Pubitemid 20276829)
    • (1990) Journal of Bone and Mineral Research , vol.5 , Issue.4 , pp. 311-319
    • Eriksen, E.F.1    Hodgson, S.F.2    Eastell, R.3    Cedel, S.L.4    O'Fallon, W.M.5    Riggs, B.L.6
  • 36
    • 31044432767 scopus 로고    scopus 로고
    • Pathogenesis of osteoporosis: Concepts, conflicts, and prospects
    • DOI 10.1172/JCI27071
    • Raisz LG. 2005. Pathogenesis of osteoporosis: concepts, conflicts, and prospects. J. Clin. Investig. 115:3318-25 (Pubitemid 43121814)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.12 , pp. 3318-3325
    • Raisz, L.G.1
  • 37
    • 0027174296 scopus 로고
    • Cytokines and estrogen in bone: Anti-osteoporotic effects
    • Horowitz MC. 1993. Cytokines and estrogen in bone: antiosteoporotic effects. Science 260:626-27 (Pubitemid 23167587)
    • (1993) Science , vol.260 , Issue.5108 , pp. 626-627
    • Horowitz, M.C.1
  • 38
    • 0028925088 scopus 로고
    • Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis
    • Manolagas SC, Jilka RL. 1995. Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis. N. Engl. J. Med. 332:305-11
    • (1995) N. Engl. J. Med. , vol.332 , pp. 305-311
    • Manolagas, S.C.1    Jilka, R.L.2
  • 39
    • 0032145401 scopus 로고    scopus 로고
    • Cytokines, bone remodeling, and estrogen deficiency: A 1998 update
    • DOI 10.1016/S8756-3282(98)00077-5, PII S8756328298000775
    • Jilka RL. 1998. Cytokines, bone remodeling, and estrogen deficiency-a 1998 update. Bone 23:75-81 (Pubitemid 28379866)
    • (1998) Bone , vol.23 , Issue.2 , pp. 75-81
    • Jilka, R.L.1
  • 40
    • 0032093690 scopus 로고    scopus 로고
    • Cytokines, estrogen, and postmenopausal osteoporosis-the second decade
    • Pacifici R. 1998. Cytokines, estrogen, and postmenopausal osteoporosis-the second decade. Endocrinol. 139:2659-61
    • (1998) Endocrinol. , vol.139 , pp. 2659-2661
    • Pacifici, R.1
  • 43
    • 0023914660 scopus 로고
    • Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells
    • Komm BS, Terpening CM, Benz DJ, Graeme KA, Gallegos A, et al. 1988. Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells. Science 241:81-83
    • (1988) Science , vol.241 , pp. 81-83
    • Komm, B.S.1    Terpening, C.M.2    Benz, D.J.3    Graeme, K.A.4    Gallegos, A.5
  • 45
    • 0026516415 scopus 로고
    • 17 â-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: A potential mechanism for the antiosteoporotic effect of estrogens
    • Girasole G, Jilka RL, Passeri G, Boswell S, Boder G, et al. 1992. 17 â-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens. J. Clin. Investig. 89:883-91
    • (1992) J. Clin. Investig. , vol.89 , pp. 883-891
    • Girasole, G.1    Jilka, R.L.2    Passeri, G.3    Boswell, S.4    Boder, G.5
  • 46
    • 0026777433 scopus 로고
    • Increased osteoclast development after estrogen loss: Mediation by interleukin-6
    • Jilka RL, Hangoc G, Girasole G, Passeri G, Williams DC, et al. 1992. Increased osteoclast development after estrogen loss: mediation by interleukin-6. Science 257:88-91
    • (1992) Science , vol.257 , pp. 88-91
    • Jilka, R.L.1    Hangoc, G.2    Girasole, G.3    Passeri, G.4    Williams, D.C.5
  • 47
    • 0034681337 scopus 로고    scopus 로고
    • Tumor necrosis factor-α induces differentiation of and bone resorption by osteoclasts
    • DOI 10.1074/jbc.275.7.4858
    • Azuma Y, Kaji K, Katogi R, Takeshita S, Kudo A. 2000. Tumor necrosis factor áinduces differentiation of and bone resorption by osteoclasts. J. Biol. Chem. 275:4858-64 (Pubitemid 30108878)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.7 , pp. 4858-4864
    • Azuma, Y.1    Kaji, K.2    Katogi, R.3    Takeshita, S.4    Kudo, A.5
  • 49
    • 0034523328 scopus 로고    scopus 로고
    • TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand
    • Lam J, Takeshita S, Barker JE, Kanagawa O, Ross FP, Teitelbaum SL. 2000. TNF-áinduces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J. Clin. Investig. 106:1481-88 (Pubitemid 32038586)
    • (2000) Journal of Clinical Investigation , vol.106 , Issue.12 , pp. 1481-1488
    • Lam, J.1    Takeshita, S.2    Barker, J.E.3    Kanagawa, O.4    Ross, F.P.5    Teitelbaum, S.L.6
  • 50
    • 1642526641 scopus 로고    scopus 로고
    • RANK signaling is not required for TNFá-mediated increase inCD11hi osteoclast precursors but is essential formature osteoclast formation in TNFá-mediated inflammatory arthritis
    • DOI 10.1359/JBMR.0301233
    • Li P, Schwarz EM, O'Keefe RJ, Ma L, Boyce BF, Xing L. 2004. RANK signaling is not required for TNFá-mediated increase inCD11hi osteoclast precursors but is essential formature osteoclast formation in TNFá-mediated inflammatory arthritis. J. Bone Miner. Res. 19:207-13 (Pubitemid 38116734)
    • (2004) Journal of Bone and Mineral Research , vol.19 , Issue.2 , pp. 207-213
    • Li, P.1    Schwarz, E.M.2    O'Keefe, R.J.3    Ma, L.4    Boyce, B.F.5    Xing, L.6
  • 52
    • 0032584208 scopus 로고    scopus 로고
    • Osteoclast differentiation factor is a ligand for osteoprotegerin/ osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
    • Yasuda H, Shima N, Nakagawa N, Yamaguchi K, Kinosaki M, et al. 1998. Osteoclast differentiation factor is a ligand for osteoprotegerin/ osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc. Natl. Acad. Sci. USA 95:3597-602
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3597-3602
    • Yasuda, H.1    Shima, N.2    Nakagawa, N.3    Yamaguchi, K.4    Kinosaki, M.5
  • 57
    • 0031439265 scopus 로고    scopus 로고
    • TRANCE (Tumor necrosis factor [TNF]-related Activation-induced Cytokine), a new TNF family member predominantly expressed in t cells, is a dendritic cell-specific survival factor
    • DOI 10.1084/jem.186.12.2075
    • Wong BR, Josien R, Lee SY, Sauter B, Li HL, et al. 1997. TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor. J. Exp. Med. 186:2075-80 (Pubitemid 28013694)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.12 , pp. 2075-2080
    • Wong, B.R.1    Josien, R.2    Lee, S.Y.3    Sauter, B.4    Li, H.-L.5    Steinman, R.M.6    Choi, Y.7
  • 58
    • 0033104614 scopus 로고    scopus 로고
    • TRANCE, a TNF family member, is differentially expressed on T cell subsets and induces cytokine production in dendritic cells
    • Josien R, Wong BR, Li HL, Steinman RM, Choi Y. 1999. TRANCE, a TNF family member, is differentially expressed on T cell subsets and induces cytokine production in dendritic cells. J. Immunol. 162:2562-68 (Pubitemid 29309274)
    • (1999) Journal of Immunology , vol.162 , Issue.5 , pp. 2562-2568
    • Josien, R.1    Wong, B.R.2    Li, H.-L.3    Steinman, R.M.4    Choi, Y.5
  • 59
    • 0033611467 scopus 로고    scopus 로고
    • OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
    • Kong YY, Yoshida H, Sarosi I, Tan HL, Timms E, et al. 1999. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 397:315-23
    • (1999) Nature , vol.397 , pp. 315-323
    • Kong, Y.Y.1    Yoshida, H.2    Sarosi, I.3    Tan, H.L.4    Timms, E.5
  • 60
    • 0033526021 scopus 로고    scopus 로고
    • TRANCE, a tumor necrosis factor family member critical for CD40 ligand- independent T helper cell activation
    • DOI 10.1084/jem.189.7.1025
    • Bachmann MF, Wong BR, Josien R, Steinman RM, Oxenius A, Choi Y. 1999. TRANCE, a tumor necrosis factor family member critical for CD40 ligand-independent T helper cell activation. J. Exp. Med. 189:1025-31 (Pubitemid 29169819)
    • (1999) Journal of Experimental Medicine , vol.189 , Issue.7 , pp. 1025-1031
    • Bachmann, M.F.1    Wong, B.R.2    Josien, R.3    Steinman, R.M.4    Oxenius, A.5    Choi, Y.6
  • 62
    • 0034730327 scopus 로고    scopus 로고
    • The osteoclast differentiation factor osteoprotegerin ligand is essential for mammary gland development
    • Fata JE, Kong YY, Li J, Sasaki T, Irie-Sasaki J, et al. 2000. The osteoclast differentiation factor osteoprotegerin ligand is essential for mammary gland development. Cell 103:41-50
    • (2000) Cell , vol.103 , pp. 41-50
    • Fata, J.E.1    Kong, Y.Y.2    Li, J.3    Sasaki, T.4    Irie-Sasaki, J.5
  • 63
    • 70849096810 scopus 로고    scopus 로고
    • Central control of fever and female body temperature by RANKL/RANK
    • Hanada R, Leibbrandt A, Hanada T, Kitaoka S, Furuyashiki T, et al. 2009. Central control of fever and female body temperature by RANKL/RANK. Nature 462:505-9
    • (2009) Nature , vol.462 , pp. 505-509
    • Hanada, R.1    Leibbrandt, A.2    Hanada, T.3    Kitaoka, S.4    Furuyashiki, T.5
  • 64
    • 0033304730 scopus 로고    scopus 로고
    • Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
    • Suda T, Takahashi N, Udagawa N, Jimi E, Gillespie MT, Martin TJ. 1999. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr. Rev. 20:345-57 (Pubitemid 30649812)
    • (1999) Endocrine Reviews , vol.20 , Issue.3 , pp. 345-357
    • Suda, T.1    Takahashi, N.2    Udagawa, N.3    Jimi, E.4    Gillespie, M.T.5    Martin, T.J.6
  • 66
    • 17044368385 scopus 로고    scopus 로고
    • Regulatory roles and molecular signaling of TNF family members in osteoclasts
    • Feng X. 2005. Regulatory roles and molecular signaling of TNF family members in osteoclasts. Gene 350:1-13
    • (2005) Gene , vol.350 , pp. 1-13
    • Feng, X.1
  • 67
    • 0030873531 scopus 로고    scopus 로고
    • +-atpase activity, calmodulin-dependent cyclic nucleotide phosphodiesterase activity, and calmodulin binding
    • DOI 10.1002/(SICI)1097-4644(19970901)66:3<358::AID-JCB8>3.0.CO;2-O
    • Williams JP, McDonald JM, McKenna MA, Jordan SE, Radding W, Blair HC. 1997. Differential effects of tamoxifen-like compounds on osteoclastic bone degradation, H+-ATPase activity, calmodulindependent cyclic nucleotide phosphodiesterase activity, and calmodulin binding. J. Cell Biochem. 66:358-69 (Pubitemid 27332869)
    • (1997) Journal of Cellular Biochemistry , vol.66 , Issue.3 , pp. 358-369
    • Williams, J.P.1    McDonald, J.M.2    McKenna, M.A.3    Jordan, S.E.4    Radding, W.5    Blair, H.C.6
  • 69
    • 0141673456 scopus 로고    scopus 로고
    • The role of calmodulin in the regulation of osteoclastogenesis
    • DOI 10.1210/en.2003-0147
    • Zhang L, Feng X, McDonald JM. 2003. The role of calmodulin in the regulation of osteoclastogenesis. Endocrinol. 144:4536-43 (Pubitemid 37204853)
    • (2003) Endocrinology , vol.144 , Issue.10 , pp. 4536-4543
    • Zhang, L.1    Feng, X.2    McDonald, J.M.3
  • 70
    • 85047681459 scopus 로고    scopus 로고
    • 17β-Estradiol stimulates expression of osteoprotegerin by a mouse stromal cell line, ST-2, via estrogen receptor-α
    • DOI 10.1210/en.142.6.2205
    • Saika M, Inoue D, Kido S, Matsumoto T. 2001. 17â-estradiol stimulates expression of osteoprotegerin by a mouse stromal cell line, ST-2, via estrogen receptor á. Endocrinology 142:2205-12 (Pubitemid 32473073)
    • (2001) Endocrinology , vol.142 , Issue.6 , pp. 2205-2212
    • Saika, M.1    Inoue, D.2    Kido, S.3    Matsumoto, T.4
  • 73
    • 0035937747 scopus 로고    scopus 로고
    • Estrogen decreases osteoclast formation by down-regulating receptor activator of NF-êB ligand (RANKL)-induced JNK activation
    • Srivastava S, Toraldo G, Weitzmann MN, Cenci S, Ross FP, Pacifici R. 2001. Estrogen decreases osteoclast formation by down-regulating receptor activator of NF-êB ligand (RANKL)-induced JNK activation. J. Biol. Chem. 276:8836-40
    • (2001) J. Biol. Chem. , vol.276 , pp. 8836-8840
    • Srivastava, S.1    Toraldo, G.2    Weitzmann, M.N.3    Cenci, S.4    Ross, F.P.5    Pacifici, R.6
  • 74
    • 0033708837 scopus 로고    scopus 로고
    • Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-á
    • Cenci S, Weitzmann MN, Roggia C, Namba N, Novack D, et al. 2000. Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-á. J. Clin. Investig. 106:1229-37
    • (2000) J. Clin. Investig. , vol.106 , pp. 1229-1237
    • Cenci, S.1    Weitzmann, M.N.2    Roggia, C.3    Namba, N.4    Novack, D.5
  • 76
    • 0344394236 scopus 로고    scopus 로고
    • Osteoclast apoptosis: The role of fas in vivo and in vitro
    • DOI 10.1210/en.2003-0296
    • Wu X, McKenna MA, Feng X, Nagy TR, McDonald JM. 2003. Osteoclast apoptosis: the role of Fas in vivo and in vitro. Endocrinology 144:5545-55 (Pubitemid 37476084)
    • (2003) Endocrinology , vol.144 , Issue.12 , pp. 5545-5555
    • Wu, X.1    McKenna, M.A.2    Feng, X.U.3    Nagy, T.R.4    McDonald, J.M.5
  • 77
    • 0034455103 scopus 로고    scopus 로고
    • Birth and death of bone cells: Basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
    • DOI 10.1210/er.21.2.115
    • Manolagas SC. 2000. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr. Rev. 21:115-37 (Pubitemid 32275592)
    • (2000) Endocrine Reviews , vol.21 , Issue.2 , pp. 115-137
    • Manolagas, S.C.1
  • 80
    • 30544443806 scopus 로고    scopus 로고
    • Estrogens and progestins: Background and history, trends in use, and guidelines and regimens approved by the US Food and Drug Administration
    • Stefanick ML. 2005. Estrogens and progestins: background and history, trends in use, and guidelines and regimens approved by the US Food and Drug Administration. Am. J. Med. 118(Suppl. 12B):64-73
    • (2005) Am. J. Med. , vol.118 , Issue.SUPPL. 12B , pp. 64-73
    • Stefanick, M.L.1
  • 81
    • 77955454685 scopus 로고    scopus 로고
    • Estrogen analogues: Selective estrogen receptor modulators and phytoestrogens
    • ed. RMarcus, D Feldman, DA Nelson, CJ Rosen, San Diego: Academic
    • Prince R, Muchmore DB, Siris ES. 2008. Estrogen analogues: selective estrogen receptor modulators and phytoestrogens. In Osteoporosis, ed. RMarcus, D Feldman, DA Nelson, CJ Rosen, pp. 1705-23. San Diego: Academic
    • (2008) Osteoporosis , pp. 1705-1723
    • Prince, R.1    Muchmore, D.B.2    Siris, E.S.3
  • 82
    • 84883937820 scopus 로고    scopus 로고
    • Bisphosphonates: Pharmacology and use in the treatment of osteoporosis
    • ed. R Marcus, D Feldman, DA Nelson, CJ Rosen, San Diego: Academic
    • Miller P. 2008. Bisphosphonates: pharmacology and use in the treatment of osteoporosis. In Osteoporosis, ed. R Marcus, D Feldman, DA Nelson, CJ Rosen, pp. 1725-42. San Diego: Academic
    • (2008) Osteoporosis , pp. 1725-1742
    • Miller, P.1
  • 84
    • 70350440129 scopus 로고    scopus 로고
    • Current and emerging pharmacologic therapies for the management of postmenopausal osteoporosis
    • Lewiecki EM. 2009. Current and emerging pharmacologic therapies for the management of postmenopausal osteoporosis. J. Womens Health 18:1615-26
    • (2009) J. Womens Health , vol.18 , pp. 1615-1626
    • Lewiecki, E.M.1
  • 85
    • 65449137137 scopus 로고    scopus 로고
    • Denosumab: Anti-RANKL antibody
    • Miller PD. 2009. Denosumab: anti-RANKL antibody. Curr. Osteoporos. Rep. 7:18-22
    • (2009) Curr. Osteoporos. Rep. , vol.7 , pp. 18-22
    • Miller, P.D.1
  • 86
    • 33845983304 scopus 로고    scopus 로고
    • The use of parathyroid hormone in the treatment of osteoporosis
    • DOI 10.1007/s11154-006-9007-z, Special Issue on Osteoporosis
    • Girotra M, Rubin MR, Bilezikian JP. 2006. The use of parathyroid hormone in the treatment of osteoporosis. Rev. Endocr. Metab Disord. 7:113-21 (Pubitemid 46049523)
    • (2006) Reviews in Endocrine and Metabolic Disorders , vol.7 , Issue.1-2 , pp. 113-121
    • Girotra, M.1    Rubin, M.R.2    Bilezikian, J.P.3
  • 87
    • 27944480412 scopus 로고    scopus 로고
    • Pathophysiology of age-related bone loss and osteoporosis
    • DOI 10.1016/j.ecl.2005.07.009, PII S0889852905000903, Endocrinology of Aging
    • Khosla S, Riggs BL. 2005. Pathophysiology of age-related bone loss and osteoporosis. Endocrinol.Metab. Clin. N. Am. 34:1015-30, xi (Pubitemid 41677410)
    • (2005) Endocrinology and Metabolism Clinics of North America , vol.34 , Issue.4 , pp. 1015-1030
    • Khosla, S.1    Riggs, B.L.2
  • 88
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • DOI 10.1016/j.cell.2005.02.001
    • Balaban RS, Nemoto S, Finkel T. 2005. Mitochondria, oxidants, and aging. Cell 120:483-95 (Pubitemid 40269763)
    • (2005) Cell , vol.120 , Issue.4 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 89
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • Finkel T, Holbrook NJ. 2000. Oxidants, oxidative stress and the biology of ageing. Nature 408:239-47
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 90
    • 34548148201 scopus 로고    scopus 로고
    • Hydrogen peroxide: A metabolic by-product or a common mediator of ageing signals?
    • DOI 10.1038/nrm2240, PII NRM2240
    • Giorgio M, Trinei M, Migliaccio E, Pelicci PG. 2007. Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? Nat. Rev. Mol. Cell Biol. 8:722-28 (Pubitemid 47312827)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.9 , pp. 722-728
    • Giorgio, M.1    Trinei, M.2    Migliaccio, E.3    Pelicci, P.G.4
  • 91
    • 34250752682 scopus 로고    scopus 로고
    • Wnt signaling and the regulation of bone mass
    • Baron R, Rawadi G. 2007. Wnt signaling and the regulation of bone mass. Curr. Osteoporos. Rep. 5:73-80 (Pubitemid 46954745)
    • (2007) Current Osteoporosis Reports , vol.5 , Issue.2 , pp. 73-80
    • Baron, R.1    Rawadi, G.2
  • 92
    • 34848814178 scopus 로고    scopus 로고
    • Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting β-catenin from T cell factor- to forkhead box O-mediated transcription
    • DOI 10.1074/jbc.M702811200
    • Almeida M, Han L, Martin-Millan M, O'Brien CA, Manolagas SC. 2007. Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting â-catenin from T cell factor-to forkhead box O-mediated transcription. J. Biol. Chem. 282:27298-305 (Pubitemid 47501978)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.37 , pp. 27298-27305
    • Almeida, M.1    Han, L.2    Martin-Millan, M.3    O'Brien, C.A.4    Manolagas, S.C.5
  • 93
    • 75149129597 scopus 로고    scopus 로고
    • From estrogen-centric to aging and oxidative stress: A revised perspective of the pathogenesis of osteoporosis
    • Manolagas SC. 2010. From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis. Endocr. Rev. 31:266-300
    • (2010) Endocr. Rev. , vol.31 , pp. 266-300
    • Manolagas, S.C.1
  • 94
    • 14844314789 scopus 로고    scopus 로고
    • Calmodulin and calmodulin-dependent kinase IIα regulate osteoblast differentiation by controlling c-fos expression
    • DOI 10.1074/jbc.M412680200
    • Zayzafoon M, Fulzele K, McDonald JM. 2005. Calmodulin and calmodulin-dependent kinase II á regulate osteoblast differentiation by controlling c-fos expression. J. Biol. Chem. 280:7049-59 (Pubitemid 40341261)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.8 , pp. 7049-7059
    • Zayzafoon, M.1    Fulzele, K.2    McDonald, J.M.3
  • 96
    • 34248674384 scopus 로고    scopus 로고
    • Cyclosporin A elicits dose-dependent biphasic effects on osteoblast differentiation and bone formation
    • DOI 10.1016/j.bone.2007.02.017, PII S8756328207000944
    • Yeo H, Beck LH, McDonald JM, Zayzafoon M. 2007. Cyclosporin A elicits dose-dependent biphasic effects on osteoblast differentiation and bone formation. Bone 40:1502-16 (Pubitemid 46766648)
    • (2007) Bone , vol.40 , Issue.6 , pp. 1502-1516
    • Yeo, H.1    Beck, L.H.2    McDonald, J.M.3    Zayzafoon, M.4
  • 97
    • 49549111375 scopus 로고    scopus 로고
    • Growth hormone, insulin-like growth factors, and the skeleton
    • Giustina A, Mazziotti G, Canalis E. 2008. Growth hormone, insulin-like growth factors, and the skeleton. Endocr. Rev. 29:535-59
    • (2008) Endocr. Rev. , vol.29 , pp. 535-559
    • Giustina, A.1    Mazziotti, G.2    Canalis, E.3
  • 99
    • 0036772984 scopus 로고    scopus 로고
    • Bone marrow adipocytes: A neglected target tissue for growth hormone
    • DOI 10.1210/en.2002-220428
    • Gevers EF, Loveridge N, Robinson IC. 2002. Bone marrow adipocytes: a neglected target tissue for growth hormone. Endocrinol. 143:4065-73 (Pubitemid 35244386)
    • (2002) Endocrinology , vol.143 , Issue.10 , pp. 4065-4073
    • Gevers, E.F.1    Loveridge, N.2    Robinson, L.C.A.F.3
  • 100
    • 0025736724 scopus 로고
    • Growth hormone (GH) receptors in clonal osteoblastlike cells mediate a mitogenic response to GH
    • Barnard R,NgKW, Martin TJ,WatersMJ. 1991. Growth hormone (GH) receptors in clonal osteoblastlike cells mediate a mitogenic response to GH. Endocrinology 128:1459-64
    • (1991) Endocrinology , vol.128 , pp. 1459-1464
    • Barnard, R.1    Ng, K.W.2    Martin, T.J.3    Waters, M.J.4
  • 101
    • 0027457962 scopus 로고
    • Growth hormone stimulates proliferation and differentiation of normal human osteoblast-like cells in vitro
    • KassemM, BlumW,Ristelli J, Mosekilde L, Eriksen EF. 1993. Growth hormone stimulates proliferation and differentiation of normal human osteoblast-like cells in vitro. Calcif. Tissue Int. 52:222-26 (Pubitemid 23090716)
    • (1993) Calcified Tissue International , vol.52 , Issue.3 , pp. 222-226
    • Kassem, M.1    Blum, W.2    Ristelli, J.3    Mosekilde, L.4    Eriksen, E.F.5
  • 102
    • 0031789821 scopus 로고    scopus 로고
    • Growth hormone and insulin-like growth factor I induce bone morphogenetic proteins 2 and 4: A mediator role in bone and tooth formation?
    • DOI 10.1210/en.139.9.3855
    • Li H, Bartold PM, Zhang CZ, Clarkson RW, Young WG, Waters MJ. 1998. Growth hormone and insulin-like growth factor I induce bone morphogenetic proteins 2 and 4: a mediator role in bone and tooth formation? Endocrinology 139:3855-62 (Pubitemid 28512268)
    • (1998) Endocrinology , vol.139 , Issue.9 , pp. 3855-3862
    • Li, H.1    Bartold, P.M.2    Zhang, C.Z.3    Clarkson, R.W.4    Young, W.G.5    Waters, M.J.6
  • 105
    • 0037302085 scopus 로고    scopus 로고
    • Role of the vitamin D-endocrine system in the pathophysiology of postmenopausal osteoporosis
    • DOI 10.1002/jcb.10345
    • Riggs BL. 2003. Role of the vitamin D-endocrine system in the pathophysiology of postmenopausal osteoporosis. J. Cell Biochem. 88:209-15 (Pubitemid 36119888)
    • (2003) Journal of Cellular Biochemistry , vol.88 , Issue.2 , pp. 209-215
    • Riggs, B.L.1
  • 106
    • 0033008459 scopus 로고    scopus 로고
    • Calcium absorption and bone loss in ovariectomized rats fed varying levels of dietary calcium
    • DOI 10.1007/s002239900660
    • Kalu DN, Orhii PB. 1999. Calcium absorption and bone loss in ovariectomized rats fed varying levels of dietary calcium. Calcif. Tissue Int. 65:73-77 (Pubitemid 29293531)
    • (1999) Calcified Tissue International , vol.65 , Issue.1 , pp. 73-77
    • Kalu, D.N.1    Orhii, P.B.2
  • 107
    • 0025033671 scopus 로고
    • Cyclic AMP induces insulin-like growth factor i synthesis in osteoblast-enriched cultures
    • McCarthy TL, Centrella M, Canalis E. 1990. Cyclic AMP induces insulin-like growth factor I synthesis in osteoblast-enriched cultures. J. Biol. Chem. 265:15353-56
    • (1990) J. Biol. Chem. , vol.265 , pp. 15353-15356
    • McCarthy, T.L.1    Centrella, M.2    Canalis, E.3
  • 108
    • 84967614664 scopus 로고    scopus 로고
    • Sex steroids and the construction and conservation of the adult skeleton
    • DOI 10.1210/er.23.3.279
    • Riggs BL, Khosla S, Melton LJ, III. 2002. Sex steroids and the construction and conservation of the adult skeleton. Endocr. Rev. 23:279-302 (Pubitemid 34651948)
    • (2002) Endocrine Reviews , vol.23 , Issue.3 , pp. 279-302
    • Riggs, B.L.1    Khosla, S.2    Melton III, L.J.3
  • 109
    • 0031756218 scopus 로고    scopus 로고
    • Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: A key role for bioavailable estrogen
    • DOI 10.1210/jc.83.7.2266
    • Khosla S, Melton LJ III, Atkinson EJ, O'FallonWM, Klee GG, Riggs BL. 1998. Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen. J. Clin. Endocrinol. Metab. 83:2266-74 (Pubitemid 28503012)
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , Issue.7 , pp. 2266-2274
    • Khosla, S.1    Melton III, L.J.2    Atkinson, E.J.3    O'Fallon, W.M.4    Klee, G.G.5    Riggs, B.L.6
  • 111
    • 73649122035 scopus 로고    scopus 로고
    • Glucocorticoid-induced osteoporosis
    • ed. R Marcus, D Feldman, DA Nelson, CJ Rosen, San Diego: Academic
    • Adler RA, Curtis J, Weinstein RS, Saag KG. 2008. Glucocorticoid-induced osteoporosis. In Osteoporosis, ed. R Marcus, D Feldman, DA Nelson, CJ Rosen, pp. 1135-66. San Diego: Academic
    • (2008) Osteoporosis , pp. 1135-1166
    • Adler, R.A.1    Curtis, J.2    Weinstein, R.S.3    Saag, K.G.4
  • 113
    • 66149114386 scopus 로고    scopus 로고
    • Trafficking and differentiation of mesenchymal stem cells
    • Liu ZJ, Zhuge Y, Velazquez OC. 2009. Trafficking and differentiation of mesenchymal stem cells. J. Cell. Biochem. 106:984-91
    • (2009) J. Cell. Biochem. , vol.106 , pp. 984-991
    • Liu, Z.J.1    Zhuge, Y.2    Velazquez, O.C.3
  • 114
    • 0033496964 scopus 로고    scopus 로고
    • Fat conversion of femoral marrow in glucocorticoid-treated patients: A cross-sectional and longitudinal study with magnetic resonance imaging
    • DOI 10.1002/1529-0131(199907)42:7<1405::AID-ANR14>3.0.CO;2-W
    • Vande Berg BC,Malghem J, Lecouvet FE, Devogelaer JP, Maldague B, Houssiau FA. 1999. Fat conversion of femoral marrow in glucocorticoid-treated patients: a cross-sectional and longitudinal study with magnetic resonance imaging. Arthritis Rheum. 42:1405-11 (Pubitemid 30265598)
    • (1999) Arthritis and Rheumatism , vol.42 , Issue.7 , pp. 1405-1411
    • Vande Berg, B.C.1    Malghem, J.2    Lecouvet, F.E.3    Devogelaer, J.-P.4    Maldague, B.5    Houssiau, F.A.6
  • 115
    • 0020730383 scopus 로고
    • Effect of glucocorticoids on type i collagen synthesis, alkaline phosphatase activity, and deoxyribonucleic acid content in cultured rat calvariae
    • Canalis E. 1983. Effect of glucocorticoids on type I collagen synthesis, alkaline phosphatase activity, and deoxyribonucleic acid content in cultured rat calvariae. Endocrinol. 112:931-39
    • (1983) Endocrinol , vol.112 , pp. 931-939
    • Canalis, E.1
  • 116
    • 0024508475 scopus 로고
    • Serum osteocalcin in the assessment of corticosteroid induced osteoporosis. Effect of long and short term corticosteroid treatment
    • Peretz A, Praet JP, Bosson D, Rozenberg S, Bourdoux P. 1989. Serum osteocalcin in the assessment of corticosteroid induced osteoporosis. Effect of long and short term corticosteroid treatment. J. Rheumatol. 16:363-67 (Pubitemid 19104577)
    • (1989) Journal of Rheumatology , vol.16 , Issue.3 , pp. 363-367
    • Peretz, A.1    Praet, J.-P.2    Bosson, D.3    Rozenberg, S.4    Bourdoux, P.5
  • 117
    • 55849147355 scopus 로고    scopus 로고
    • Glucocorticoid-induced bone loss in mice can be reversed by the actions of parathyroid hormone and risedronate on different pathways for bone formation and mineralization
    • YaoW, Cheng Z, Pham A, Busse C, Zimmermann EA, et al. 2008. Glucocorticoid-induced bone loss in mice can be reversed by the actions of parathyroid hormone and risedronate on different pathways for bone formation and mineralization. Arthritis Rheum. 58:3485-97
    • (2008) Arthritis Rheum. , vol.58 , pp. 3485-3497
    • Yao, W.1    Cheng, Z.2    Pham, A.3    Busse, C.4    Zimmermann, E.A.5
  • 118
    • 0032528180 scopus 로고    scopus 로고
    • Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts end osteocytes by glucocorticoids potential mechanisms of their deleterious effects on bone
    • WeinsteinRS, JilkaRL, ParfittAM,Manolagas SC. 1998. Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone. J. Clin. Investig. 102:274-82 (Pubitemid 28335186)
    • (1998) Journal of Clinical Investigation , vol.102 , Issue.2 , pp. 274-282
    • Weinstein, R.S.1    Jilka, R.L.2    Michael Parfitt, A.3    Manolagas, S.C.4
  • 119
    • 0033304809 scopus 로고    scopus 로고
    • Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: Potential paracrine mechanisms of glucocorticoid-induced osteoporosis
    • Hofbauer LC, Gori F, Riggs BL, Lacey DL, Dunstan CR, et al. 1999. Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis. Endocrinol. 140:4382-89 (Pubitemid 30666099)
    • (1999) Endocrinology , vol.140 , Issue.10 , pp. 4382-4389
    • Hofbauer, L.C.1    Gori, F.2    Riggs, B.L.3    Lacey, D.L.4    Dunstan, C.R.5    Spelsberg, T.C.6    Khosla, S.7
  • 120
    • 33751501004 scopus 로고    scopus 로고
    • Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density
    • DOI 10.1210/en.2006-0459
    • Jia D, O'Brien CA, Stewart SA, Manolagas SC, Weinstein RS. 2006. Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density. Endocrinol. 147:5592-99 (Pubitemid 44833476)
    • (2006) Endocrinology , vol.147 , Issue.12 , pp. 5592-5599
    • Jia, D.1    O'Brien, C.A.2    Stewart, S.A.3    Manolagas, S.C.4    Weinstein, R.S.5
  • 123
    • 34548554688 scopus 로고    scopus 로고
    • Glucocorticoid-induced osteoporosis: Pathophysiology and therapy
    • DOI 10.1007/s00198-007-0394-0
    • Canalis E, Mazziotti G, Giustina A, Bilezikian JP. 2007. Glucocorticoid-induced osteoporosis: pathophysiology and therapy. Osteoporos. Int. 18:1319-28 (Pubitemid 47389469)
    • (2007) Osteoporosis International , vol.18 , Issue.10 , pp. 1319-1328
    • Canalis, E.1    Mazziotti, G.2    Giustina, A.3    Bilezikian, J.P.4
  • 127
    • 0030977163 scopus 로고    scopus 로고
    • Effects of 1- and 6-month spaceflight on bone mass and biochemistry in two humans
    • DOI 10.1016/S8756-3282(97)00052-5, PII S8756328297000525
    • Collet P, Uebelhart D, Vico L, Moro L, Hartmann D, et al. 1997. Effects of 1-and 6-month spaceflight on bone mass and biochemistry in two humans. Bone 20:547-51 (Pubitemid 27270469)
    • (1997) Bone , vol.20 , Issue.6 , pp. 547-551
    • Collet, Ph.1    Uebelhart, D.2    Vico, L.3    Moro, L.4    Hartmann, D.5    Roth, M.6    Alexandre, C.7
  • 128
    • 12344309568 scopus 로고    scopus 로고
    • Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight
    • DOI 10.1359/JBMR.040307
    • Lang T, LeBlanc A, Evans H, Lu Y, Genant H, Yu A. 2004. Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight. J. Bone Miner. Res. 19:1006-12 (Pubitemid 41103458)
    • (2004) Journal of Bone and Mineral Research , vol.19 , Issue.6 , pp. 1006-1012
    • Lang, T.1    LeBlanc, A.2    Evans, H.3    Lu, Y.4    Genant, H.5    Yu, A.6
  • 130
    • 12544258956 scopus 로고    scopus 로고
    • Bone markers, calcium metabolism, and calcium kinetics during extended-duration space flight on the Mir space station
    • Smith SM, Wastney ME, O'Brien KO, Morukov BV, Larina IM, et al. 2005. Bone markers, calcium metabolism, and calcium kinetics during extended-duration space flight on the Mir space station. J. Bone Miner. Res. 20:208-18
    • (2005) J. Bone Miner. Res. , vol.20 , pp. 208-218
    • Smith, S.M.1    Wastney, M.E.2    O'Brien, K.O.3    Morukov, B.V.4    Larina, I.M.5
  • 131
    • 0033804637 scopus 로고    scopus 로고
    • Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow
    • You J, Yellowley CE, Donahue HJ, Zhang Y, Chen Q, Jacobs CR. 2000. Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow. J. Biomech. Eng. 122:387-93
    • (2000) J. Biomech. Eng. , vol.122 , pp. 387-393
    • You, J.1    Yellowley, C.E.2    Donahue, H.J.3    Zhang, Y.4    Chen, Q.5    Jacobs, C.R.6
  • 134
    • 0033197546 scopus 로고    scopus 로고
    • Osteoclastogenesis is repressed by mechanical strain in an in vitro model
    • Rubin J, Fan X, Biskobing DM, Taylor WR, Rubin CT. 1999. Osteoclastogenesis is repressed by mechanical strain in an in vitro model. J. Orthop. Res. 17:639-45
    • (1999) J. Orthop. Res. , vol.17 , pp. 639-645
    • Rubin, J.1    Fan, X.2    Biskobing, D.M.3    Taylor, W.R.4    Rubin, C.T.5
  • 135
    • 0035992651 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinase is involved in mechanical strain inhibition of RANKL expression in bone stromal cells
    • Rubin J, Murphy TC, Fan X, Goldschmidt M, Taylor WR. 2002. Activation of extracellular signalregulated kinase is involved in mechanical strain inhibition of RANKL expression in bone stromal cells. J. Bone Miner. Res. 17:1452-60 (Pubitemid 34803829)
    • (2002) Journal of Bone and Mineral Research , vol.17 , Issue.8 , pp. 1452-1460
    • Rubin, J.1    Murphy, T.C.2    Fan, X.3    Goldschmidt, M.4    Taylor, W.R.5
  • 136
  • 137
    • 79951675663 scopus 로고    scopus 로고
    • Modeled microgravity and hindlimb unloading sensitize osteoclast precursors to RANKL-mediated osteoclastogenesis
    • press
    • Saxena R, Pan G, Dohm EK, McDonald JM. 2010. Modeled microgravity and hindlimb unloading sensitize osteoclast precursors to RANKL-mediated osteoclastogenesis. J. Bone Miner. Metab. In press
    • (2010) J. Bone Miner. Metab.
    • Saxena, R.1    Pan, G.2    Dohm, E.K.3    McDonald, J.M.4
  • 138
    • 33344455592 scopus 로고    scopus 로고
    • Molecular pathways mediating mechanical signaling in bone
    • DOI 10.1016/j.gene.2005.10.028, PII S0378111905006013
    • Rubin J, Rubin C, Jacobs CR. 2006. Molecular pathways mediating mechanical signaling in bone. Gene 367:1-16 (Pubitemid 43286736)
    • (2006) Gene , vol.367 , Issue.1-2 , pp. 1-16
    • Rubin, J.1    Rubin, C.2    Jacobs, C.R.3
  • 139
    • 72149125600 scopus 로고    scopus 로고
    • Boning up on Wolff 's Law: Mechanical regulation of the cells that make and maintain bone
    • Chen JH, Liu C, You L, Simmons CA. 2010. Boning up on Wolff 's Law: mechanical regulation of the cells that make and maintain bone. J. Biomech. 43:108-18
    • (2010) J. Biomech. , vol.43 , pp. 108-118
    • Chen, J.H.1    Liu, C.2    You, L.3    Simmons, C.A.4
  • 140
    • 54249151301 scopus 로고    scopus 로고
    • Role for â1 integrins in cortical osteocytes during acute musculoskeletal disuse
    • Phillips JA, Almeida EA, Hill EL, Aguirre JI, Rivera MF, et al. 2008. Role for â1 integrins in cortical osteocytes during acute musculoskeletal disuse. Matrix Biol. 27:609-18
    • (2008) Matrix Biol. , vol.27 , pp. 609-618
    • Phillips, J.A.1    Almeida, E.A.2    Hill, E.L.3    Aguirre, J.I.4    Rivera, M.F.5
  • 142
    • 21744453509 scopus 로고    scopus 로고
    • Modeled microgravity disrupts collagen I/integrin signaling during osteoblastic differentiation of human mesenchymal stem cells
    • DOI 10.1002/jcb.20229
    • Meyers VE, Zayzafoon M, Gonda SR, Gathings WE, McDonald JM. 2004. Modeled microgravity disrupts collagen I/integrin signaling during osteoblastic differentiation of human mesenchymal stem cells. J. Cell Biochem. 93:697-707 (Pubitemid 44264166)
    • (2004) Journal of Cellular Biochemistry , vol.93 , Issue.4 , pp. 697-707
    • Meyers, V.E.1    Zayzafoon, M.2    Gonda, S.R.3    Gathings, W.E.4    McDonald, J.M.5
  • 143
    • 25444492582 scopus 로고    scopus 로고
    • RhoA and cytoskeletal disruption mediate reduced osteoblastogenesis and enhanced adipogenesis of human mesenchymal stem cells in modeled microgravity
    • DOI 10.1359/JBMR.050611
    • Meyers VE, Zayzafoon M, Douglas JT,McDonald JM. 2005. RhoA and cytoskeletal disruption mediate reduced osteoblastogenesis and enhanced adipogenesis of human mesenchymal stem cells in modeled microgravity. J. Bone Miner. Res. 20:1858-66 (Pubitemid 41361888)
    • (2005) Journal of Bone and Mineral Research , vol.20 , Issue.10 , pp. 1858-1866
    • Meyers, V.E.1    Zayzafoon, M.2    Douglas, J.T.3    McDonald, J.M.4
  • 146
    • 33745269019 scopus 로고    scopus 로고
    • Morbidity and mortality associated with abnormalities in bone and mineral metabolism in CKD
    • ed. K Olgaard, New York: Natl. Kidney Found
    • Block GA, Cunningham J. 2006. Morbidity and mortality associated with abnormalities in bone and mineral metabolism in CKD. In Clinical Guide to the Basics of Bone and Mineral Metabolism in CKD, ed. K Olgaard, pp. 77-92. New York: Natl. Kidney Found.
    • (2006) Clinical Guide to the Basics of Bone and Mineral Metabolism in CKD , pp. 77-92
    • Block, G.A.1    Cunningham, J.2
  • 147
    • 33645757920 scopus 로고    scopus 로고
    • Definition, evaluation, and classification of renal osteodystrophy: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO)
    • DOI 10.1038/sj.ki.5000414, PII 5000414
    • Moe S, Drueke T, Cunningham J, Goodman W, Martin K, et al. 2006. Definition, evaluation, and classification of renal osteodystrophy: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int. 69:1945-53 (Pubitemid 43924257)
    • (2006) Kidney International , vol.69 , Issue.11 , pp. 1945-1953
    • Moe, S.1    Drueke, T.2    Cunningham, J.3    Goodman, W.4    Martin, K.5    Olgaard, K.6    Ott, S.7    Sprague, S.8    Lameire, N.9    Eknoyan, G.10
  • 149
    • 84889490803 scopus 로고    scopus 로고
    • Chronic kidney disease mineral bone disorder (CKD-MBD)
    • ed. CJ Rosen, Washington, DC: Am. Soc. Bone Miner. Res
    • HruskaKA. 2008. Chronic kidney disease mineral bone disorder (CKD-MBD). In Primer on theMetabolic Bone Diseases and Disorders of Mineral Metabolism, ed. CJ Rosen, pp. 343-49. Washington, DC: Am. Soc. Bone Miner. Res.
    • (2008) Primer on TheMetabolic Bone Diseases and Disorders of Mineral Metabolism , pp. 343-349
    • Hruska, K.A.1
  • 150
    • 70350519843 scopus 로고    scopus 로고
    • Paget disease: When to treat and when not to treat
    • Singer FR. 2009. Paget disease: when to treat and when not to treat. Nat. Rev. Rheumatol. 5:483-89
    • (2009) Nat. Rev. Rheumatol. , vol.5 , pp. 483-489
    • Singer, F.R.1
  • 151
    • 0030938128 scopus 로고    scopus 로고
    • Natural history of untreated Paget's disease of the tibia
    • DOI 10.1359/jbmr.1997.12.4.691
    • Siris ES, Feldman F. 1997. Natural history of untreated Paget's disease of the tibia. J. Bone Miner. Res. 12: 691-92 (Pubitemid 27155230)
    • (1997) Journal of Bone and Mineral Research , vol.12 , Issue.4 , pp. 691-692
    • Siris, E.S.1    Feldman, F.2
  • 152
    • 0029249407 scopus 로고
    • Extensive personal experience: Paget's disease of bone
    • Siris ES. 1995. Extensive personal experience: Paget's disease of bone. J. Clin. Endocrinol. Metab. 80:335-38
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 335-338
    • Siris, E.S.1
  • 153
    • 77649189746 scopus 로고    scopus 로고
    • Gene expression profile in osteoclasts from patients with Paget's disease of bone
    • Michou L, Chamoux E, Couture J, Morissette J, Brown JP, Roux S. 2010. Gene expression profile in osteoclasts from patients with Paget's disease of bone. Bone 46:598-603
    • (2010) Bone , vol.46 , pp. 598-603
    • Michou, L.1    Chamoux, E.2    Couture, J.3    Morissette, J.4    Brown, J.P.5    Roux, S.6


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