메뉴 건너뛰기




Volumn , Issue , 2008, Pages 1705-1723

Estrogen Analogues: Selective Estrogen Receptor Modulators and Phytoestrogens

Author keywords

[No Author keywords available]

Indexed keywords


EID: 77955454685     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012370544-0.50075-6     Document Type: Chapter
Times cited : (4)

References (110)
  • 1
    • 0030921703 scopus 로고    scopus 로고
    • Phytoestrogens reduce bone loss and bone resorption in oophorectomized rats
    • Draper C.R., Edel M.J., Dick I.M., Randall A.G., Martin G.B., Prince R.L. Phytoestrogens reduce bone loss and bone resorption in oophorectomized rats. J Nutr 1997, 127(9):1795-1799.
    • (1997) J Nutr , vol.127 , Issue.9 , pp. 1795-1799
    • Draper, C.R.1    Edel, M.J.2    Dick, I.M.3    Randall, A.G.4    Martin, G.B.5    Prince, R.L.6
  • 2
    • 0029841146 scopus 로고    scopus 로고
    • Identification of an estrogen response element activated by metabolites of 17β-estradiol and raloxifene
    • Yang N.N., Venugopalan M., Hardikar S., Glasebrook A. Identification of an estrogen response element activated by metabolites of 17β-estradiol and raloxifene. Science 1996, 273(5279):1222-1225.
    • (1996) Science , vol.273 , Issue.5279 , pp. 1222-1225
    • Yang, N.N.1    Venugopalan, M.2    Hardikar, S.3    Glasebrook, A.4
  • 4
    • 0015295806 scopus 로고
    • Steroid and phyto-oestrogen binding to sheep uterine receptors in vitro
    • Shutt D.A., Cox R.I. Steroid and phyto-oestrogen binding to sheep uterine receptors in vitro. J Endocrinol 1972, 52(2):299-310.
    • (1972) J Endocrinol , vol.52 , Issue.2 , pp. 299-310
    • Shutt, D.A.1    Cox, R.I.2
  • 5
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta
    • Kuiper G.G., Carlsson B., Grandien K., Enmark E., Haggblad J., Nilsson S., Gustafsson J.A. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 1997, 138(3):863-870.
    • (1997) Endocrinology , vol.138 , Issue.3 , pp. 863-870
    • Kuiper, G.G.1    Carlsson, B.2    Grandien, K.3    Enmark, E.4    Haggblad, J.5    Nilsson, S.6    Gustafsson, J.A.7
  • 6
    • 0032752637 scopus 로고    scopus 로고
    • Developmental effects of dietary phytoestrogens in Sprague-Dawley rats and interactions of genistein and daidzein with rat estrogen receptors alpha and beta in vitro
    • Casanova M., You L., Gaido K.W., Archibeque-Engle S., Janszen D.B., Heck H.A. Developmental effects of dietary phytoestrogens in Sprague-Dawley rats and interactions of genistein and daidzein with rat estrogen receptors alpha and beta in vitro. Toxicol Sci 1999, 51(2):236-244.
    • (1999) Toxicol Sci , vol.51 , Issue.2 , pp. 236-244
    • Casanova, M.1    You, L.2    Gaido, K.W.3    Archibeque-Engle, S.4    Janszen, D.B.5    Heck, H.A.6
  • 7
    • 0028225760 scopus 로고
    • Urinary lignan and isoflavonoid excretion in premenopausal women consuming flaxseed powder
    • Lampe J.W., Martini M.C., Kurzer M.S., Adlercreutz H., Slavin J.L. Urinary lignan and isoflavonoid excretion in premenopausal women consuming flaxseed powder. Am J Clin Nutr 1994, 60(1):122-128.
    • (1994) Am J Clin Nutr , vol.60 , Issue.1 , pp. 122-128
    • Lampe, J.W.1    Martini, M.C.2    Kurzer, M.S.3    Adlercreutz, H.4    Slavin, J.L.5
  • 8
    • 0028280245 scopus 로고
    • Stimulation of pS2 expression by diet-derived compounds
    • Sathyamoorthy N., Wang T.T., Phang J.M. Stimulation of pS2 expression by diet-derived compounds. Cancer Res 1994, 54(4):957-961.
    • (1994) Cancer Res , vol.54 , Issue.4 , pp. 957-961
    • Sathyamoorthy, N.1    Wang, T.T.2    Phang, J.M.3
  • 9
    • 3242798960 scopus 로고    scopus 로고
    • Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor {alpha} (ER{alpha}) and ER{beta} in human cells
    • Mueller S.O., Simon S., Chae K., Metzler M., Korach K.S. Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor {alpha} (ER{alpha}) and ER{beta} in human cells. Toxicol Sci 2004, 80(1):14-25.
    • (2004) Toxicol Sci , vol.80 , Issue.1 , pp. 14-25
    • Mueller, S.O.1    Simon, S.2    Chae, K.3    Metzler, M.4    Korach, K.S.5
  • 10
    • 33751506983 scopus 로고    scopus 로고
    • Minireview: Estrogen receptor-mediated rapid signaling
    • Moriarty K., Kim K.H., Bender J.R. Minireview: Estrogen receptor-mediated rapid signaling. Endocrinology 2006, 147(12):5557-5563.
    • (2006) Endocrinology , vol.147 , Issue.12 , pp. 5557-5563
    • Moriarty, K.1    Kim, K.H.2    Bender, J.R.3
  • 14
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
    • Shiau A.K., Barstad D., Loria P.M., Cheng L., Kushner P.J., Agard D.A., Greene G.L. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 1998, 95(7):927-937.
    • (1998) Cell , vol.95 , Issue.7 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3    Cheng, L.4    Kushner, P.J.5    Agard, D.A.6    Greene, G.L.7
  • 15
    • 0026600841 scopus 로고
    • Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors
    • Danielian P.S., White R., Lees J.A., Parker M.G. Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors. EMBO J 1992, 11(3):1025-1033.
    • (1992) EMBO J , vol.11 , Issue.3 , pp. 1025-1033
    • Danielian, P.S.1    White, R.2    Lees, J.A.3    Parker, M.G.4
  • 16
    • 0029978077 scopus 로고    scopus 로고
    • Human estrogen receptor ligand activity inversion mutants: Receptors that interpret antiestrogens as estrogens and estrogens as antiestrogens and discriminate among different antiestrogens
    • Montano M.M., Ekena K., Krueger K.D., Keller A.L., Katzenellenbogen B.S. Human estrogen receptor ligand activity inversion mutants: Receptors that interpret antiestrogens as estrogens and estrogens as antiestrogens and discriminate among different antiestrogens. Mol Endocrinol 1996, 10(3):230-242.
    • (1996) Mol Endocrinol , vol.10 , Issue.3 , pp. 230-242
    • Montano, M.M.1    Ekena, K.2    Krueger, K.D.3    Keller, A.L.4    Katzenellenbogen, B.S.5
  • 17
    • 0032472911 scopus 로고    scopus 로고
    • Different positioning of the ligand-binding domain helix 12 and the F domain of the estrogen receptor accounts for functional differences between agonists and antagonists
    • Nichols M., Rientjes J.M., Stewart A.F. Different positioning of the ligand-binding domain helix 12 and the F domain of the estrogen receptor accounts for functional differences between agonists and antagonists. EMBO J 1998, 17(3):765-773.
    • (1998) EMBO J , vol.17 , Issue.3 , pp. 765-773
    • Nichols, M.1    Rientjes, J.M.2    Stewart, A.F.3
  • 18
    • 2642593030 scopus 로고    scopus 로고
    • The key to the antiestrogenic mechanism of raloxifene is amino acid 351 (aspartate) in the estrogen receptor
    • Levenson A.S., Jordan V.C. The key to the antiestrogenic mechanism of raloxifene is amino acid 351 (aspartate) in the estrogen receptor. Cancer Res 1998, 58(9):1872-1875.
    • (1998) Cancer Res , vol.58 , Issue.9 , pp. 1872-1875
    • Levenson, A.S.1    Jordan, V.C.2
  • 19
    • 0031008040 scopus 로고    scopus 로고
    • Estrogenic activity is increased for an antiestrogen by a natural mutation of the estrogen receptor
    • Levenson A.S., Catherino W.H., Jordan V.C. Estrogenic activity is increased for an antiestrogen by a natural mutation of the estrogen receptor. J Steroid Biochem Mol Biol 1997, 60(5-6):261-268.
    • (1997) J Steroid Biochem Mol Biol , vol.60 , Issue.5-6 , pp. 261-268
    • Levenson, A.S.1    Catherino, W.H.2    Jordan, V.C.3
  • 20
    • 0031561119 scopus 로고    scopus 로고
    • Agonistic effect of tamoxifen is dependent on cell type, ERE-promoter context, and estrogen receptor subtype: Functional difference between estrogen receptors alpha and beta
    • Watanabe T., Inoue S., Ogawa S., Ishii Y., Hiroi H., Ikeda K., Orimo A., Muramatsu M. Agonistic effect of tamoxifen is dependent on cell type, ERE-promoter context, and estrogen receptor subtype: Functional difference between estrogen receptors alpha and beta. Biochem Biophys Res Commun 1997, 236(1):140-145.
    • (1997) Biochem Biophys Res Commun , vol.236 , Issue.1 , pp. 140-145
    • Watanabe, T.1    Inoue, S.2    Ogawa, S.3    Ishii, Y.4    Hiroi, H.5    Ikeda, K.6    Orimo, A.7    Muramatsu, M.8
  • 21
    • 1442351143 scopus 로고    scopus 로고
    • Coregulator function: A key to understanding tissue specificity of selective receptor modulators
    • Smith C.L., O'Malley B.W. Coregulator function: A key to understanding tissue specificity of selective receptor modulators. Endocr Rev 2004, 25(1):45-71.
    • (2004) Endocr Rev , vol.25 , Issue.1 , pp. 45-71
    • Smith, C.L.1    O'Malley, B.W.2
  • 24
    • 0029038986 scopus 로고
    • Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens
    • McDonnell D.P., Clemm D.L., Hermann T., Goldman M.E., Pike J.W. Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens. Mol Endocrinol 1995, 9(6):659-669.
    • (1995) Mol Endocrinol , vol.9 , Issue.6 , pp. 659-669
    • McDonnell, D.P.1    Clemm, D.L.2    Hermann, T.3    Goldman, M.E.4    Pike, J.W.5
  • 26
    • 0034680924 scopus 로고    scopus 로고
    • Differential effects of xenoestrogens on coactivator recruitment by estrogen receptor (ER) alpha and ERbeta
    • Routledge E.J., White R., Parker M.G., Sumpter J.P. Differential effects of xenoestrogens on coactivator recruitment by estrogen receptor (ER) alpha and ERbeta. J Biol Chem 2000, 275(46):35986-35993.
    • (2000) J Biol Chem , vol.275 , Issue.46 , pp. 35986-35993
    • Routledge, E.J.1    White, R.2    Parker, M.G.3    Sumpter, J.P.4
  • 27
    • 0038360744 scopus 로고    scopus 로고
    • Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors alpha and beta
    • Rickard D.J., Monroe D.G., Ruesink T.J., Khosla S., Riggs B.L., Spelsberg T.C. Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors alpha and beta. J Cell Biochem 2003, 89(3):633-646.
    • (2003) J Cell Biochem , vol.89 , Issue.3 , pp. 633-646
    • Rickard, D.J.1    Monroe, D.G.2    Ruesink, T.J.3    Khosla, S.4    Riggs, B.L.5    Spelsberg, T.C.6
  • 28
    • 3242798960 scopus 로고    scopus 로고
    • Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor alpha (ERalpha) and ERbeta in human cells
    • Mueller S.O., Simon S., Chae K., Metzler M., Korach K.S. Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor alpha (ERalpha) and ERbeta in human cells. Toxicol Sci 2004, 80(1):14-25.
    • (2004) Toxicol Sci , vol.80 , Issue.1 , pp. 14-25
    • Mueller, S.O.1    Simon, S.2    Chae, K.3    Metzler, M.4    Korach, K.S.5
  • 29
    • 0029968829 scopus 로고    scopus 로고
    • Estrogen and estrogen receptor antagonists stimulate transcription from the human retinoic acid receptor-alpha 1 promoter via a novel sequence
    • Elgort M.G., Zou A., Marschke K.B., Allegretto E.A. Estrogen and estrogen receptor antagonists stimulate transcription from the human retinoic acid receptor-alpha 1 promoter via a novel sequence. Mol Endocrinol 1996, 10(5):477-487.
    • (1996) Mol Endocrinol , vol.10 , Issue.5 , pp. 477-487
    • Elgort, M.G.1    Zou, A.2    Marschke, K.B.3    Allegretto, E.A.4
  • 30
    • 0030801841 scopus 로고    scopus 로고
    • Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites
    • Paech K., Webb P., Kuiper G.G., Nilsson S., Gustafsson J., Kushner P.J., Scanlan T.S. Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites. Science 1997, 277(5331):1508-1510.
    • (1997) Science , vol.277 , Issue.5331 , pp. 1508-1510
    • Paech, K.1    Webb, P.2    Kuiper, G.G.3    Nilsson, S.4    Gustafsson, J.5    Kushner, P.J.6    Scanlan, T.S.7
  • 31
    • 0031789876 scopus 로고    scopus 로고
    • Transcription activation by the human estrogen receptor subtype beta (ER beta) studied with ER beta and ER alpha receptor chimeras
    • McInerney E.M., Weis K.E., Sun J., Mosselman S., Katzenellenbogen B.S. Transcription activation by the human estrogen receptor subtype beta (ER beta) studied with ER beta and ER alpha receptor chimeras. Endocrinology 1998, 139(11):4513-4522.
    • (1998) Endocrinology , vol.139 , Issue.11 , pp. 4513-4522
    • McInerney, E.M.1    Weis, K.E.2    Sun, J.3    Mosselman, S.4    Katzenellenbogen, B.S.5
  • 32
    • 0004752110 scopus 로고    scopus 로고
    • Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta
    • Sun J., Meyers M.J., Fink B.E., Rajendran R., Katzenellenbogen J.A., Katzenellenbogen B.S. Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta. Endocrinology 1999, 140(2):800-804.
    • (1999) Endocrinology , vol.140 , Issue.2 , pp. 800-804
    • Sun, J.1    Meyers, M.J.2    Fink, B.E.3    Rajendran, R.4    Katzenellenbogen, J.A.5    Katzenellenbogen, B.S.6
  • 37
    • 0028787563 scopus 로고
    • Dietary estrogenic isoflavones are potent inhibitors of beta-hydroxysteroid dehydrogenase of P
    • Keung W.M. Dietary estrogenic isoflavones are potent inhibitors of beta-hydroxysteroid dehydrogenase of P. testosteronii. Biochem Biophys Res Commun 1995, 215(3):1137-1144.
    • (1995) testosteronii. Biochem Biophys Res Commun , vol.215 , Issue.3 , pp. 1137-1144
    • Keung, W.M.1
  • 38
    • 0028972676 scopus 로고
    • Inhibition of 5 alpha-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids
    • Evans B.A., Griffiths K., Morton M.S. Inhibition of 5 alpha-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids. J Endocrinol 1995, 147(2):295-302.
    • (1995) J Endocrinol , vol.147 , Issue.2 , pp. 295-302
    • Evans, B.A.1    Griffiths, K.2    Morton, M.S.3
  • 39
    • 0034712219 scopus 로고    scopus 로고
    • Effects of phytoestrogens on aromatase, 3beta and 17betahydroxysteroid dehydrogenase activities and human breast cancer cells
    • Le Bail J.C., Champavier Y., Chulia A.J., Habrioux G. Effects of phytoestrogens on aromatase, 3beta and 17betahydroxysteroid dehydrogenase activities and human breast cancer cells. Life Sci 2000, 66(14):1281-1291.
    • (2000) Life Sci , vol.66 , Issue.14 , pp. 1281-1291
    • Le Bail, J.C.1    Champavier, Y.2    Chulia, A.J.3    Habrioux, G.4
  • 40
    • 0029119281 scopus 로고
    • Regulation of sex hormone-binding globulin production by isoflavonoids and patterns of isoflavonoid conjugation in HepG2 cell cultures
    • Loukovaara M., Carson M., Palotie A., Adlercreutz H. Regulation of sex hormone-binding globulin production by isoflavonoids and patterns of isoflavonoid conjugation in HepG2 cell cultures. Steroids 1995, 60(9):656-661.
    • (1995) Steroids , vol.60 , Issue.9 , pp. 656-661
    • Loukovaara, M.1    Carson, M.2    Palotie, A.3    Adlercreutz, H.4
  • 41
    • 0021889704 scopus 로고
    • Inhibition of in vitro microsomal lipid peroxidation by isoflavonoids
    • Jha H.C., von Recklinghausen G., Zilliken F. Inhibition of in vitro microsomal lipid peroxidation by isoflavonoids. Biochem Pharmacol 1985, 34(9):1367-1369.
    • (1985) Biochem Pharmacol , vol.34 , Issue.9 , pp. 1367-1369
    • Jha, H.C.1    von Recklinghausen, G.2    Zilliken, F.3
  • 43
    • 0025373318 scopus 로고
    • Interaction of phytoestrogens and other environmental estrogens with prostaglandin synthase in vitro
    • Degen G.H. Interaction of phytoestrogens and other environmental estrogens with prostaglandin synthase in vitro. J Steroid Biochem 1990, 35(3-4):473-479.
    • (1990) J Steroid Biochem , vol.35 , Issue.3-4 , pp. 473-479
    • Degen, G.H.1
  • 44
    • 0028786569 scopus 로고
    • Yeast two-hybrid system demonstrates that estrogen receptor dimerization is ligand-dependent in vivo
    • Wang H., Peters G.A., Zeng X., Tang M., Ip W., Khan S.A. Yeast two-hybrid system demonstrates that estrogen receptor dimerization is ligand-dependent in vivo. J Biol Chem 1995, 270(40):23322-23329.
    • (1995) J Biol Chem , vol.270 , Issue.40 , pp. 23322-23329
    • Wang, H.1    Peters, G.A.2    Zeng, X.3    Tang, M.4    Ip, W.5    Khan, S.A.6
  • 45
    • 0022657951 scopus 로고
    • Effects of the antiestrogens tamoxifen and clomiphene on bone resorption in vitro
    • Stewart P.J., Stern P.H. Effects of the antiestrogens tamoxifen and clomiphene on bone resorption in vitro. Endocrinology 1986, 118(1):125-131.
    • (1986) Endocrinology , vol.118 , Issue.1 , pp. 125-131
    • Stewart, P.J.1    Stern, P.H.2
  • 47
    • 0023430358 scopus 로고
    • Tamoxifen prevents the skeletal effects of ovarian hormone deficiency in rats
    • Turner R.T., Wakley G.K., Hannon K.S., Bell N.H. Tamoxifen prevents the skeletal effects of ovarian hormone deficiency in rats. J Bone Miner Res 1987, 2(5):449-456.
    • (1987) J Bone Miner Res , vol.2 , Issue.5 , pp. 449-456
    • Turner, R.T.1    Wakley, G.K.2    Hannon, K.S.3    Bell, N.H.4
  • 48
    • 0025062310 scopus 로고
    • Effects of clomiphene and tamoxifen in vivo on the bone-resorbing effects of parathyroid hormone and of high oral doses of calcitriol(1,25(OH)2D3) in rats with intact ovarian function consuming low calcium diet
    • Goulding A., Gold E., Fisher L. Effects of clomiphene and tamoxifen in vivo on the bone-resorbing effects of parathyroid hormone and of high oral doses of calcitriol(1,25(OH)2D3) in rats with intact ovarian function consuming low calcium diet. Bone Miner 1990, 8:185-193.
    • (1990) Bone Miner , vol.8 , pp. 185-193
    • Goulding, A.1    Gold, E.2    Fisher, L.3
  • 49
    • 0023930991 scopus 로고
    • Tamoxifen inhibits osteoclast-mediated resorption of trabecular bone in ovarian hormone-deficient rats
    • Turner R.T., Wakley G.K., Hannon K.S., Bell N.H. Tamoxifen inhibits osteoclast-mediated resorption of trabecular bone in ovarian hormone-deficient rats. Endocrinology 1988, 122(3):1146-1150.
    • (1988) Endocrinology , vol.122 , Issue.3 , pp. 1146-1150
    • Turner, R.T.1    Wakley, G.K.2    Hannon, K.S.3    Bell, N.H.4
  • 50
    • 14244266609 scopus 로고    scopus 로고
    • Tamoxifen stimulates cancellous bone formation in long bones of female mice
    • Perry M.J., Gujra S., Whitworth T., Tobias J.H. Tamoxifen stimulates cancellous bone formation in long bones of female mice. Endocrinology 2005, 146(3):1060-1065.
    • (2005) Endocrinology , vol.146 , Issue.3 , pp. 1060-1065
    • Perry, M.J.1    Gujra, S.2    Whitworth, T.3    Tobias, J.H.4
  • 52
    • 0028951607 scopus 로고
    • Longitudinal and cross-sectional analysis of raloxifene effects on tibiae from ovariectomized aged rats
    • Sato M., Kim J., Short L.L., Slemenda C.W., Bryant H.U. Longitudinal and cross-sectional analysis of raloxifene effects on tibiae from ovariectomized aged rats. J Pharmacol Exp Ther 1995, 272(3):1252-1259.
    • (1995) J Pharmacol Exp Ther , vol.272 , Issue.3 , pp. 1252-1259
    • Sato, M.1    Kim, J.2    Short, L.L.3    Slemenda, C.W.4    Bryant, H.U.5
  • 53
    • 0029759978 scopus 로고    scopus 로고
    • Raloxifene inhibits bone turnover and prevents further cancellous bone loss in adult ovariectomized rats with established osteopenia
    • Evans G.L., Bryant H.U., Magee D.E., Turner R.T. Raloxifene inhibits bone turnover and prevents further cancellous bone loss in adult ovariectomized rats with established osteopenia. Endocrinology 1996, 137(10):4139-4144.
    • (1996) Endocrinology , vol.137 , Issue.10 , pp. 4139-4144
    • Evans, G.L.1    Bryant, H.U.2    Magee, D.E.3    Turner, R.T.4
  • 54
    • 0028212448 scopus 로고
    • The effects of raloxifene on tibia histomorphometry in ovariectomized rats
    • Evans G., Bryant H.U., Magee D., Sato M., Turner R.T. The effects of raloxifene on tibia histomorphometry in ovariectomized rats. Endocrinology 1994, 134(5):2283-2288.
    • (1994) Endocrinology , vol.134 , Issue.5 , pp. 2283-2288
    • Evans, G.1    Bryant, H.U.2    Magee, D.3    Sato, M.4    Turner, R.T.5
  • 55
    • 0000392972 scopus 로고    scopus 로고
    • Raloxifene increases bone mass and reduces bone turnover in ovariectomized cynomolgous monkeys
    • Jerome C., Lees C.J. Raloxifene increases bone mass and reduces bone turnover in ovariectomized cynomolgous monkeys. J Bone Miner Res 1996, 11(Suppl. 1):S445.
    • (1996) J Bone Miner Res , vol.11 , Issue.SUPPL. 1
    • Jerome, C.1    Lees, C.J.2
  • 56
    • 0030176408 scopus 로고    scopus 로고
    • Time-dependent changes in biochemical bone markers and serum cholesterol in ovariectomized rats: Effects of raloxifene HCl, tamoxifen, estrogen, and alendronate
    • Frolik C.A., Bryant H.U., Black E.C., Magee D.E., Chandrasekhar S. Time-dependent changes in biochemical bone markers and serum cholesterol in ovariectomized rats: Effects of raloxifene HCl, tamoxifen, estrogen, and alendronate. Bone 1996, 18(6):621-627.
    • (1996) Bone , vol.18 , Issue.6 , pp. 621-627
    • Frolik, C.A.1    Bryant, H.U.2    Black, E.C.3    Magee, D.E.4    Chandrasekhar, S.5
  • 58
    • 0028061884 scopus 로고
    • Raloxifene preserves bone strength and bone mass in ovariectomized rats
    • Turner C.H., Sato M., Bryant H.U. Raloxifene preserves bone strength and bone mass in ovariectomized rats. Endocrinology 1994, 135(5):2001-2005.
    • (1994) Endocrinology , vol.135 , Issue.5 , pp. 2001-2005
    • Turner, C.H.1    Sato, M.2    Bryant, H.U.3
  • 59
    • 0036896165 scopus 로고    scopus 로고
    • Long-term dosing of arzoxifene lowers cholesterol, reduces bone turnover, and preserves bone quality in ovariectomized rats
    • Ma Y.L., Bryant H.U., Zeng Q., Palkowitz A., Jee W.S., Turner C.H., Sato M. Long-term dosing of arzoxifene lowers cholesterol, reduces bone turnover, and preserves bone quality in ovariectomized rats. J Bone Miner Res 2002, 17(12):2256-2264.
    • (2002) J Bone Miner Res , vol.17 , Issue.12 , pp. 2256-2264
    • Ma, Y.L.1    Bryant, H.U.2    Zeng, Q.3    Palkowitz, A.4    Jee, W.S.5    Turner, C.H.6    Sato, M.7
  • 60
    • 0034056092 scopus 로고    scopus 로고
    • Protein tyrosine kinase inhibitors increase cytosolic calcium and inhibit actin organization as resorbing activity in rat osteoclasts
    • Kajiya H., Okabe K., Okamoto F., Tsuzuki T., Soeda H. Protein tyrosine kinase inhibitors increase cytosolic calcium and inhibit actin organization as resorbing activity in rat osteoclasts. J Cell Physiol 2000, 183(1):83-90.
    • (2000) J Cell Physiol , vol.183 , Issue.1 , pp. 83-90
    • Kajiya, H.1    Okabe, K.2    Okamoto, F.3    Tsuzuki, T.4    Soeda, H.5
  • 61
    • 0032836223 scopus 로고    scopus 로고
    • Suppressive effect of genistein on rat bone osteoclasts: Apoptosis is induced through Ca2+ signaling
    • Gao Y.H., Yamaguchi M. Suppressive effect of genistein on rat bone osteoclasts: Apoptosis is induced through Ca2+ signaling. Biol Pharm Bull 1999, 22(8):805-809.
    • (1999) Biol Pharm Bull , vol.22 , Issue.8 , pp. 805-809
    • Gao, Y.H.1    Yamaguchi, M.2
  • 62
    • 0032985097 scopus 로고    scopus 로고
    • Anabolic effect of daidzein on cortical bone in tissue culture: Comparison with genistein effect
    • Gao Y.H., Yamaguchi M. Anabolic effect of daidzein on cortical bone in tissue culture: Comparison with genistein effect. Mol Cell Biochem 1999, 194(1-2):93-97.
    • (1999) Mol Cell Biochem , vol.194 , Issue.1-2 , pp. 93-97
    • Gao, Y.H.1    Yamaguchi, M.2
  • 63
    • 0031886079 scopus 로고    scopus 로고
    • Anabolic effect of genistein and genistin on bone metabolism in the femoral-metaphyseal tissues of elderly rats: The genistein effect is enhanced by zinc
    • Yamaguchi M., Gao Y.H. Anabolic effect of genistein and genistin on bone metabolism in the femoral-metaphyseal tissues of elderly rats: The genistein effect is enhanced by zinc. Mol Cell Biochem 1998, 178(1-2):377-382.
    • (1998) Mol Cell Biochem , vol.178 , Issue.1-2 , pp. 377-382
    • Yamaguchi, M.1    Gao, Y.H.2
  • 65
    • 0031770982 scopus 로고    scopus 로고
    • Role of soy protein with normal or reduced isoflavone content in reversing bone loss induced by ovarian hormone deficiency in rats
    • Arjmandi B.H., Getlinger M.J., Goyal N.V., Alekel L., Hasler C.M., Juma S., Drum M.L., Hollis B.W., Kukreja S.C. Role of soy protein with normal or reduced isoflavone content in reversing bone loss induced by ovarian hormone deficiency in rats. Am J Clin Nutr 1998, 68(6 Suppl):1358S-1363S.
    • (1998) Am J Clin Nutr , vol.68 , Issue.6 SUPPL
    • Arjmandi, B.H.1    Getlinger, M.J.2    Goyal, N.V.3    Alekel, L.4    Hasler, C.M.5    Juma, S.6    Drum, M.L.7    Hollis, B.W.8    Kukreja, S.C.9
  • 70
    • 0031952143 scopus 로고    scopus 로고
    • Biphasic effects of genistein on bone tissue in the ovariectomized, lactating rat model
    • Anderson J.J., Ambrose W.W., Garner S.C. Biphasic effects of genistein on bone tissue in the ovariectomized, lactating rat model. Proc Soc Exp Biol Med 1998, 217(3):345-350.
    • (1998) Proc Soc Exp Biol Med , vol.217 , Issue.3 , pp. 345-350
    • Anderson, J.J.1    Ambrose, W.W.2    Garner, S.C.3
  • 71
    • 33744825972 scopus 로고    scopus 로고
    • Genistein alone and in combination with the mammalian lignans enterolactone and enterodiol induce estrogenic effects on bone and uterus in a postmenopausal breast cancer mouse model
    • Power K.A., Ward W.E., Chen J.M., Saarinen N.M., Thompson L.U. Genistein alone and in combination with the mammalian lignans enterolactone and enterodiol induce estrogenic effects on bone and uterus in a postmenopausal breast cancer mouse model. Bone 2006, 39(1):117-124.
    • (2006) Bone , vol.39 , Issue.1 , pp. 117-124
    • Power, K.A.1    Ward, W.E.2    Chen, J.M.3    Saarinen, N.M.4    Thompson, L.U.5
  • 73
    • 0034011493 scopus 로고    scopus 로고
    • Prolonged intake of fermented soybean (natto) diets containing vitamin K2 (menaquinone-7) prevents bone loss in ovariectomized rats
    • Yamaguchi M., Kakuda H., Gao Y.H., Tsukamoto Y. Prolonged intake of fermented soybean (natto) diets containing vitamin K2 (menaquinone-7) prevents bone loss in ovariectomized rats. J Bone Miner Metab 2000, 18(2):71-76.
    • (2000) J Bone Miner Metab , vol.18 , Issue.2 , pp. 71-76
    • Yamaguchi, M.1    Kakuda, H.2    Gao, Y.H.3    Tsukamoto, Y.4
  • 74
    • 0029152026 scopus 로고
    • Effect of coumestrol on bone metabolism in organ culture
    • Tsutsumi N. Effect of coumestrol on bone metabolism in organ culture. Biol Pharm Bull 1995, 18(7):1012-1015.
    • (1995) Biol Pharm Bull , vol.18 , Issue.7 , pp. 1012-1015
    • Tsutsumi, N.1
  • 77
    • 0027965779 scopus 로고
    • The effect of tochu bark on bone metabolism in the rat model with ovariectomized osteoporosis
    • Jiu L.J., Morikawa N., Omi N., Ezawa I. The effect of tochu bark on bone metabolism in the rat model with ovariectomized osteoporosis. J Nutr Sci Vitaminol (Tokyo) 1994, 40(3):261-273.
    • (1994) J Nutr Sci Vitaminol (Tokyo) , vol.40 , Issue.3 , pp. 261-273
    • Jiu, L.J.1    Morikawa, N.2    Omi, N.3    Ezawa, I.4
  • 80
    • 0142241154 scopus 로고    scopus 로고
    • Estrogen, D vitamin, and calcium transport
    • Christakos S., Prince R. Estrogen, D vitamin, and calcium transport. J Bone Miner Res 2003, 18(10):1737-1739.
    • (2003) J Bone Miner Res , vol.18 , Issue.10 , pp. 1737-1739
    • Christakos, S.1    Prince, R.2
  • 81
    • 0030963994 scopus 로고    scopus 로고
    • Raloxifene and estrogen: Comparative bone-remodeling kinetics
    • Heaney R.P., Draper M.W. Raloxifene and estrogen: Comparative bone-remodeling kinetics. J Clin Endocrinol Metab 1997, 82(10):3425-3429.
    • (1997) J Clin Endocrinol Metab , vol.82 , Issue.10 , pp. 3425-3429
    • Heaney, R.P.1    Draper, M.W.2
  • 82
    • 0030664688 scopus 로고    scopus 로고
    • Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women
    • Delmas P.D., Bjarnason N.H., Mitlak B.H., Ravoux A.C., Shah A.S., Huster W.J., Draper M., Christiansen C. Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women. N Engl J Med 1997, 337(23):1641-1647.
    • (1997) N Engl J Med , vol.337 , Issue.23 , pp. 1641-1647
    • Delmas, P.D.1    Bjarnason, N.H.2    Mitlak, B.H.3    Ravoux, A.C.4    Shah, A.S.5    Huster, W.J.6    Draper, M.7    Christiansen, C.8
  • 88
    • 0041328600 scopus 로고    scopus 로고
    • Effects of raloxifene hydrochloride on bone mineral density, bone metabolism and serum lipids in postmenopausal women: A randomized clinical trial in Beijing
    • Zheng S., Wu Y., Zhang Z., Yang X., Hui Y., Zhang Y., Chen S., Deng W., Liu H., Ekangaki A., Stocks J., Harper K., Liu J. Effects of raloxifene hydrochloride on bone mineral density, bone metabolism and serum lipids in postmenopausal women: A randomized clinical trial in Beijing. Chin Med J (Engl) 2003, 116(8):1127-1133.
    • (2003) Chin Med J (Engl) , vol.116 , Issue.8 , pp. 1127-1133
    • Zheng, S.1    Wu, Y.2    Zhang, Z.3    Yang, X.4    Hui, Y.5    Zhang, Y.6    Chen, S.7    Deng, W.8    Liu, H.9    Ekangaki, A.10    Stocks, J.11    Harper, K.12    Liu, J.13
  • 89
    • 0344877301 scopus 로고    scopus 로고
    • Effect of raloxifene on bone mineral density and biochemical markers of bone turnover in Japanese postmenopausal women with osteoporosis: Results from a randomized placebo-controlled trial
    • Morii H., Ohashi Y., Taketani Y., Fukunaga M., Nakamura T., Itabashi A., Sarkar S., Harper K. Effect of raloxifene on bone mineral density and biochemical markers of bone turnover in Japanese postmenopausal women with osteoporosis: Results from a randomized placebo-controlled trial. Osteoporos Int 2003, 14(10):793-800.
    • (2003) Osteoporos Int , vol.14 , Issue.10 , pp. 793-800
    • Morii, H.1    Ohashi, Y.2    Taketani, Y.3    Fukunaga, M.4    Nakamura, T.5    Itabashi, A.6    Sarkar, S.7    Harper, K.8
  • 92
    • 0036963450 scopus 로고    scopus 로고
    • Additive effects of raloxifene and alendronate on bone density and biochemical markers of bone remodeling in postmenopausal women with osteoporosis
    • Johnell O., Scheele W.H., Lu Y., Reginster J.Y., Need A.G., Seeman E. Additive effects of raloxifene and alendronate on bone density and biochemical markers of bone remodeling in postmenopausal women with osteoporosis. J Clin Endocrinol Metab 2002, 87(3):985-992.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.3 , pp. 985-992
    • Johnell, O.1    Scheele, W.H.2    Lu, Y.3    Reginster, J.Y.4    Need, A.G.5    Seeman, E.6
  • 93
    • 8444250575 scopus 로고    scopus 로고
    • Treatment with raloxifene for 2 years increases vertebral bone mineral density as measured by volumetric quantitative computed tomography
    • Genant H.K., Lang T., Fuerst T., Pinette K.V., Zhou C., Thiebaud D., Diez-Perez A. Treatment with raloxifene for 2 years increases vertebral bone mineral density as measured by volumetric quantitative computed tomography. Bone 2004, 35(5):1164-1168.
    • (2004) Bone , vol.35 , Issue.5 , pp. 1164-1168
    • Genant, H.K.1    Lang, T.2    Fuerst, T.3    Pinette, K.V.4    Zhou, C.5    Thiebaud, D.6    Diez-Perez, A.7
  • 94
    • 0141676029 scopus 로고    scopus 로고
    • Contribution of raloxifene and calcium and vitamin D3 supplementation to the increase of the degree of mineralization of bone in postmenopausal women
    • Boivin G., Lips P., Ott S.M., Harper K.D., Sarkar S., Pinette K.V., Meunier P.J. Contribution of raloxifene and calcium and vitamin D3 supplementation to the increase of the degree of mineralization of bone in postmenopausal women. J Clin Endocrinol Metab 2003, 88(9):4199-4205.
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.9 , pp. 4199-4205
    • Boivin, G.1    Lips, P.2    Ott, S.M.3    Harper, K.D.4    Sarkar, S.5    Pinette, K.V.6    Meunier, P.J.7
  • 95
    • 0344445501 scopus 로고    scopus 로고
    • Effects of raloxifene, hormone replacement therapy, and placebo on bone turnover in postmenopausal women
    • Weinstein R.S., Parfitt A.M., et al. Effects of raloxifene, hormone replacement therapy, and placebo on bone turnover in postmenopausal women. Osteoporos Int 2003, 14:814-822.
    • (2003) Osteoporos Int , vol.14 , pp. 814-822
    • Weinstein, R.S.1    Parfitt, A.M.2
  • 96
    • 0037182042 scopus 로고    scopus 로고
    • Early effects of raloxifene on clinical vertebral fractures at 12 months in postmenopausal women with osteoporosis
    • Maricic M., Adachi J.D., Sarkar S., Wu W., Wong M., Harper K.D. Early effects of raloxifene on clinical vertebral fractures at 12 months in postmenopausal women with osteoporosis. Arch Intern Med 2002, 162(10):1140-1143.
    • (2002) Arch Intern Med , vol.162 , Issue.10 , pp. 1140-1143
    • Maricic, M.1    Adachi, J.D.2    Sarkar, S.3    Wu, W.4    Wong, M.5    Harper, K.D.6
  • 99
    • 10644283864 scopus 로고    scopus 로고
    • Continuing outcomes relevant to Evista: Breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene
    • Martino S., Cauley J.A., Barrett-Connor E., Powles T.J., Mershon J., Disch D., Secrest R.J., Cummings S.R. Continuing outcomes relevant to Evista: Breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene. J Natl Cancer Inst 2004, 96(23):1751-1761.
    • (2004) J Natl Cancer Inst , vol.96 , Issue.23 , pp. 1751-1761
    • Martino, S.1    Cauley, J.A.2    Barrett-Connor, E.3    Powles, T.J.4    Mershon, J.5    Disch, D.6    Secrest, R.J.7    Cummings, S.R.8
  • 101
    • 13244277629 scopus 로고    scopus 로고
    • Cost-effectiveness of raloxifene in the UK: An economic evaluation based on the MORE study
    • Kanis J.A., Borgstrom F., Johnell O., Oden A., Sykes D., Jonsson B. Cost-effectiveness of raloxifene in the UK: An economic evaluation based on the MORE study. Osteoporos Int 2005, 16(1):15-25.
    • (2005) Osteoporos Int , vol.16 , Issue.1 , pp. 15-25
    • Kanis, J.A.1    Borgstrom, F.2    Johnell, O.3    Oden, A.4    Sykes, D.5    Jonsson, B.6
  • 104
    • 14344267019 scopus 로고    scopus 로고
    • Gut bacterial metabolism of the soy isoflavone daidzein: Exploring the relevance to human health
    • Atkinson C., Frankenfeld C.L., Lampe J.W. Gut bacterial metabolism of the soy isoflavone daidzein: Exploring the relevance to human health. Exp Biol Med (Maywood) 2005, 230(3):155-170.
    • (2005) Exp Biol Med (Maywood) , vol.230 , Issue.3 , pp. 155-170
    • Atkinson, C.1    Frankenfeld, C.L.2    Lampe, J.W.3
  • 105
    • 0028343434 scopus 로고
    • Daidzein is a more bioavailable soymilk isoflavone than is genistein in adult women
    • Xu X., Wang H.J., Murphy P.A., Cook L., Hendrich S. Daidzein is a more bioavailable soymilk isoflavone than is genistein in adult women. J Nutr 1994, 124(6):825-832.
    • (1994) J Nutr , vol.124 , Issue.6 , pp. 825-832
    • Xu, X.1    Wang, H.J.2    Murphy, P.A.3    Cook, L.4    Hendrich, S.5
  • 106
    • 0031772172 scopus 로고    scopus 로고
    • Soy protein and isoflavones: Their effects on blood lipids and bone density in postmenopausal women
    • Potter S.M., Baum J.A., Teng H., Stillman R.J., Shay N.F., Erdman J.W. Soy protein and isoflavones: Their effects on blood lipids and bone density in postmenopausal women. Am J Clin Nutr 1998, 68(6 Suppl):1375S-1379S.
    • (1998) Am J Clin Nutr , vol.68 , Issue.6 SUPPL
    • Potter, S.M.1    Baum, J.A.2    Teng, H.3    Stillman, R.J.4    Shay, N.F.5    Erdman, J.W.6
  • 107
    • 1342328575 scopus 로고    scopus 로고
    • The effects of phytoestrogen isoflavones on bone density in women: A double-blind, randomized, placebo-controlled trial
    • Atkinson C., Compston J.E., Day N.E., Dowsett M., Bingham S.A. The effects of phytoestrogen isoflavones on bone density in women: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2004, 79(2):326-333.
    • (2004) Am J Clin Nutr , vol.79 , Issue.2 , pp. 326-333
    • Atkinson, C.1    Compston, J.E.2    Day, N.E.3    Dowsett, M.4    Bingham, S.A.5
  • 108
    • 3042821848 scopus 로고    scopus 로고
    • Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: A randomized controlled trial
    • Kreijkamp-Kaspers S., Kok L., Grobbee D.E., de Haan E.H., Aleman A., Lampe J.W., van der Schouw Y.T. Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: A randomized controlled trial. JAMA 2004, 292(1):65-74.
    • (2004) JAMA , vol.292 , Issue.1 , pp. 65-74
    • Kreijkamp-Kaspers, S.1    Kok, L.2    Grobbee, D.E.3    de Haan, E.H.4    Aleman, A.5    Lampe, J.W.6    van der Schouw, Y.T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.