Modeled microgravity disrupts collagen I/integrin signaling during osteoblastic differentiation of human mesenchymal stem cells

Journal of Cellular Biochemistry

Volumn 93, Issue 4, 2004, Pages 697-707

  Meyers, Valerie E ^a   Zayzafoon, Majd ^a   Gonda, Steve R ^b   Gathings, William E ^c   McDonald, Jay M ^a,d  

^a University of Alabama at Birmingham   (United States)

^b NASA JOHNSON SPACE CENTER   (United States)

^c UNIVERSITY OF ALABAMA IN HUNTSVILLE   (United States)

^d BIRMINGHAM VA MEDICAL CENTER   (United States)

Author keywords

Collagen; FAK; HARV; Integrin; MAPK; Osteoblast; RCCS

Indexed keywords

COLLAGEN TYPE 1; INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE; FOCAL ADHESION KINASE; FOCAL ADHESION KINASE 1; FOCAL ADHESION KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN TYROSINE KINASE; PTK2 PROTEIN, HUMAN; VERY LATE ACTIVATION ANTIGEN 2;

ARTICLE; BONE DENSITY; BONE DEVELOPMENT; CELL DIFFERENTIATION; ENZYME ACTIVATION; HUMAN; MESENCHYMAL STEM CELL; MICROGRAVITY; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SPACE FLIGHT; BIOSYNTHESIS; CYTOLOGY; METABOLISM; NASA DISCIPLINE CELL BIOTECHNOLOGY; NON-NASA CENTER; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; WEIGHTLESSNESS;

NASA DISCIPLINE CELL BIOTECHNOLOGY; NON-NASA CENTER;

CELL DIFFERENTIATION; COLLAGEN TYPE I; FOCAL ADHESION KINASE 1; FOCAL ADHESION KINASE 2; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; INTEGRIN ALPHA2BETA1; INTEGRINS; MAP KINASE SIGNALING SYSTEM; MESENCHYMAL STEM CELLS; MITOGEN-ACTIVATED PROTEIN KINASE 1; OSTEOBLASTS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; WEIGHTLESSNESS SIMULATION;

EID: 21744453509     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.20229     Document Type: Article

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