P38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis

Oncogene

Volumn 30, Issue 5, 2011, Pages 588-599

  Delston, R B ^a   Matatall, K A ^a   Sun, Y ^a   Onken, M D ^a   Harbour, J W ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

apoptosis; Hdm2; p38; phosphorylation; retinoblastoma protein

Indexed keywords

CYCLIN DEPENDENT KINASE; HOMOLOG OF MURINE DOUBLE MINUTE 2 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; RETINOBLASTOMA PROTEIN; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE PHASE; CELL DEATH; CELL DIVISION; CONTROLLED STUDY; ENZYME REGULATION; GENOTOXICITY; HUMAN; HUMAN CELL; MELANOMA CELL; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; E2F1 TRANSCRIPTION FACTOR; ETOPOSIDE; HUMANS; IMMUNOBLOTTING; MITOGEN-ACTIVATED PROTEIN KINASE 14; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-MDM2; PURINES; RETINOBLASTOMA PROTEIN; RNA INTERFERENCE; SERINE; TUMOR SUPPRESSOR PROTEIN P53;

MURINAE;

EID: 79551622682     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.442     Document Type: Article

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