The central acidic domain of MDM2 is critical in inhibition of retinoblastoma-mediated suppression of E2F and cell growth

Journal of Biological Chemistry

Volumn 279, Issue 51, 2004, Pages 53317-53322

  Sdek, Patima ^a   Ying, Haoqiang ^a   Zheng, Hongwu ^a,b   Margulis, Alexander ^a   Tang, Xiaoren ^a   Tian, Kui ^a   Xiao, Zhi Xiong Jim ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; GROWTH KINETICS; TUMORS;

MALIGNANCIES; MUTANTS; RETINOBLASTOMA (RB); TUMOR SUPPRESSORS;

PROTEINS;

PROTEIN MDM2; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F;

ARTICLE; CANCER CELL; CARCINOGENESIS; CELL GROWTH; COMPLEX FORMATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RETINOBLASTOMA; STRUCTURE ANALYSIS; TRANSCRIPTION INITIATION; WILD TYPE;

AMINO ACID SEQUENCE; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL DIVISION; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA-BINDING PROTEINS; E2F TRANSCRIPTION FACTORS; GENES, REPORTER; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; MACROMOLECULAR SUBSTANCES; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PROTEINS; PHOSPHORYLATION; PLASMIDS; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; PROTO-ONCOGENES; RECOMBINANT FUSION PROTEINS; RETINOBLASTOMA PROTEIN; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 11144241617     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M406062200     Document Type: Article

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