Hepatitis B virus X protein via the p38MAPK pathway induces E2F1 release and ATR kinase activation mediating p53 apoptosis

Journal of Biological Chemistry

Volumn 283, Issue 37, 2008, Pages 25455-25467

  Wang, Wen Horng ^a   Hullinger, Ronald L ^a   Andrisani, Ourania M ^a,b  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; CHEMICAL REACTIONS; GENES; NUCLEIC ACIDS; ORGANIC ACIDS; PHOSPHORYLATION; RUBIDIUM; TRANSCRIPTION; VIRUSES;

APOPTOSIS; APOPTOTIC GENES; DNA DAMAGES; HEPATITIS B VIRUSES; HEPATOCELLULAR CARCINOMATA; HEPATOCYTES; KINASE ACTIVATIONS; TRANSCRIPTIONAL FUNCTIONS;

CELL DEATH;

ATR PROTEIN; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; FAS ANTIGEN; HEPATITIS B VIRUS X PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN NOXA; PROTEIN P53; RETINOBLASTOMA PROTEIN; SERINE; TRANSCRIPTION FACTOR E2F1; ATR PROTEIN, MOUSE; CELL CYCLE PROTEIN; CYCLOHEXIMIDE; PROTEIN SERINE THREONINE KINASE; PROTEIN SYNTHESIS INHIBITOR; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVATION; GENETIC TRANSCRIPTION; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN STABILITY; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; METABOLISM; SIGNAL TRANSDUCTION;

HEPATITIS B VIRUS;

ANIMALS; APOPTOSIS; CELL CYCLE PROTEINS; CYCLOHEXIMIDE; E2F1 TRANSCRIPTION FACTOR; MAP KINASE SIGNALING SYSTEM; MICE; MODELS, BIOLOGICAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN SYNTHESIS INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; RETINOBLASTOMA PROTEIN; SERINE; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 54449091313     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M801934200     Document Type: Article

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