메뉴 건너뛰기




Volumn 15, Issue 3, 2009, Pages 184-194

Proapoptotic Function of the Retinoblastoma Tumor Suppressor Protein

Author keywords

CELLCYCLE

Indexed keywords

E1A PROTEIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F1;

EID: 60649094957     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2009.01.026     Document Type: Article
Times cited : (119)

References (41)
  • 1
    • 0029050533 scopus 로고
    • Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis
    • Almasan A., Yin Y., Kelly R.E., Lee E.Y., Bradley A., Li W., Bertino J.R., and Wahl G.M. Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis. Proc. Natl. Acad. Sci. USA 92 (1995) 5436-5440
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5436-5440
    • Almasan, A.1    Yin, Y.2    Kelly, R.E.3    Lee, E.Y.4    Bradley, A.5    Li, W.6    Bertino, J.R.7    Wahl, G.M.8
  • 4
    • 1242297828 scopus 로고    scopus 로고
    • RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult
    • Bosco E.E., Mayhew C.N., Hennigan R.F., Sage J., Jacks T., and Knudsen E.S. RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult. Nucleic Acids Res. 32 (2004) 25-34
    • (2004) Nucleic Acids Res. , vol.32 , pp. 25-34
    • Bosco, E.E.1    Mayhew, C.N.2    Hennigan, R.F.3    Sage, J.4    Jacks, T.5    Knudsen, E.S.6
  • 5
    • 0032146778 scopus 로고    scopus 로고
    • Radiation-induced apoptosis mediated by retinoblastoma protein
    • Bowen C., Spiegel S., and Gelmann E.P. Radiation-induced apoptosis mediated by retinoblastoma protein. Cancer Res. 58 (1998) 3275-3281
    • (1998) Cancer Res. , vol.58 , pp. 3275-3281
    • Bowen, C.1    Spiegel, S.2    Gelmann, E.P.3
  • 6
    • 0347721777 scopus 로고    scopus 로고
    • Retinoblastoma protein-mediated apoptosis after gamma-irradiation
    • Bowen C., Birrer M., and Gelmann E.P. Retinoblastoma protein-mediated apoptosis after gamma-irradiation. J. Biol. Chem. 277 (2002) 44969-44979
    • (2002) J. Biol. Chem. , vol.277 , pp. 44969-44979
    • Bowen, C.1    Birrer, M.2    Gelmann, E.P.3
  • 7
    • 0034760521 scopus 로고    scopus 로고
    • Retinoblastoma protein complexes with C/EBP proteins and activates C/EBP-mediated transcription
    • Charles A., Tang X., Crouch E., Brody J.S., and Xiao Z.X. Retinoblastoma protein complexes with C/EBP proteins and activates C/EBP-mediated transcription. J. Cell. Biochem. 83 (2001) 414-425
    • (2001) J. Cell. Biochem. , vol.83 , pp. 414-425
    • Charles, A.1    Tang, X.2    Crouch, E.3    Brody, J.S.4    Xiao, Z.X.5
  • 8
    • 0036884829 scopus 로고    scopus 로고
    • The retinoblastoma tumour suppressor in development and cancer
    • Classon M., and Harlow E. The retinoblastoma tumour suppressor in development and cancer. Nat. Rev. Cancer 2 (2002) 910-917
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 910-917
    • Classon, M.1    Harlow, E.2
  • 11
    • 0141927097 scopus 로고    scopus 로고
    • pRB contains an E2F1-specific binding domain that allows E2F1-induced apoptosis to be regulated separately from other E2F activities
    • Dick F.A., and Dyson N. pRB contains an E2F1-specific binding domain that allows E2F1-induced apoptosis to be regulated separately from other E2F activities. Mol. Cell 12 (2003) 639-649
    • (2003) Mol. Cell , vol.12 , pp. 639-649
    • Dick, F.A.1    Dyson, N.2
  • 13
    • 0027489749 scopus 로고
    • Independent regions of adenovirus E1A are required for binding to and dissociation of E2F-protein complexes
    • Fattaey A.R., Harlow E., and Helin K. Independent regions of adenovirus E1A are required for binding to and dissociation of E2F-protein complexes. Mol. Cell. Biol. 13 (1993) 7267-7277
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7267-7277
    • Fattaey, A.R.1    Harlow, E.2    Helin, K.3
  • 14
    • 2942722811 scopus 로고    scopus 로고
    • Molecular mechanisms of E2F-dependent activation and pRB-mediated repression
    • Frolov M.V., and Dyson N.J. Molecular mechanisms of E2F-dependent activation and pRB-mediated repression. J. Cell Sci. 117 (2004) 2173-2181
    • (2004) J. Cell Sci. , vol.117 , pp. 2173-2181
    • Frolov, M.V.1    Dyson, N.J.2
  • 15
    • 1442302765 scopus 로고    scopus 로고
    • C/EBPepsilon interacts with retinoblastoma and E2F1 during granulopoiesis
    • Gery S., Gombart A.F., Fung Y.K., and Koeffler H.P. C/EBPepsilon interacts with retinoblastoma and E2F1 during granulopoiesis. Blood 103 (2004) 828-835
    • (2004) Blood , vol.103 , pp. 828-835
    • Gery, S.1    Gombart, A.F.2    Fung, Y.K.3    Koeffler, H.P.4
  • 16
    • 33644862798 scopus 로고    scopus 로고
    • The related retinoblastoma (pRb) and p130 proteins cooperate to regulate homeostasis in the intestinal epithelium
    • Haigis K., Sage J., Glickman J., Shafer S., and Jacks T. The related retinoblastoma (pRb) and p130 proteins cooperate to regulate homeostasis in the intestinal epithelium. J. Biol. Chem. 281 (2006) 638-647
    • (2006) J. Biol. Chem. , vol.281 , pp. 638-647
    • Haigis, K.1    Sage, J.2    Glickman, J.3    Shafer, S.4    Jacks, T.5
  • 17
    • 0037330709 scopus 로고    scopus 로고
    • Mechanisms by which DNA tumor virus oncoproteins target the Rb family of pocket proteins
    • Helt A.M., and Galloway D.A. Mechanisms by which DNA tumor virus oncoproteins target the Rb family of pocket proteins. Carcinogenesis 24 (2003) 159-169
    • (2003) Carcinogenesis , vol.24 , pp. 159-169
    • Helt, A.M.1    Galloway, D.A.2
  • 18
    • 0029820095 scopus 로고    scopus 로고
    • The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway
    • Hofmann F., Martelli F., Livingston D.M., and Wang Z. The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway. Genes Dev. 10 (1996) 2949-2959
    • (1996) Genes Dev. , vol.10 , pp. 2949-2959
    • Hofmann, F.1    Martelli, F.2    Livingston, D.M.3    Wang, Z.4
  • 19
    • 4544378400 scopus 로고    scopus 로고
    • Rb is required for progression through myogenic differentiation but not maintenance of terminal differentiation
    • Huh M.S., Parker M.H., Scime A., Parks R., and Rudnicki M.A. Rb is required for progression through myogenic differentiation but not maintenance of terminal differentiation. J. Cell Biol. 166 (2004) 865-876
    • (2004) J. Cell Biol. , vol.166 , pp. 865-876
    • Huh, M.S.1    Parker, M.H.2    Scime, A.3    Parks, R.4    Rudnicki, M.A.5
  • 20
    • 3142711538 scopus 로고    scopus 로고
    • Specific role for p300/CREB-binding protein-associated factor activity in E2F1 stabilization in response to DNA damage
    • Ianari A., Gallo R., Palma M., Alesse E., and Gulino A. Specific role for p300/CREB-binding protein-associated factor activity in E2F1 stabilization in response to DNA damage. J. Biol. Chem. 279 (2004) 30830-30835
    • (2004) J. Biol. Chem. , vol.279 , pp. 30830-30835
    • Ianari, A.1    Gallo, R.2    Palma, M.3    Alesse, E.4    Gulino, A.5
  • 21
    • 36749050812 scopus 로고    scopus 로고
    • Life and death decisions by the E2F transcription factors
    • Iaquinta P.J., and Lees J.A. Life and death decisions by the E2F transcription factors. Curr. Opin. Cell Biol. 19 (2007) 649-657
    • (2007) Curr. Opin. Cell Biol. , vol.19 , pp. 649-657
    • Iaquinta, P.J.1    Lees, J.A.2
  • 23
    • 0033575960 scopus 로고    scopus 로고
    • The retinoblastoma tumor suppressor inhibits cellular proliferation through two distinct mechanisms: inhibition of cell cycle progression and induction of cell death
    • Knudsen K.E., Weber E., Arden K.C., Cavenee W.K., Feramisco J.R., and Knudsen E.S. The retinoblastoma tumor suppressor inhibits cellular proliferation through two distinct mechanisms: inhibition of cell cycle progression and induction of cell death. Oncogene 18 (1999) 5239-5245
    • (1999) Oncogene , vol.18 , pp. 5239-5245
    • Knudsen, K.E.1    Weber, E.2    Arden, K.C.3    Cavenee, W.K.4    Feramisco, J.R.5    Knudsen, E.S.6
  • 25
    • 33645746494 scopus 로고    scopus 로고
    • Inactivation of conditional Rb by Villin-Cre leads to aggressive tumors outside the gastrointestinal tract
    • Kucherlapati M.H., Nguyen A.A., Bronson R.T., and Kucherlapati R.S. Inactivation of conditional Rb by Villin-Cre leads to aggressive tumors outside the gastrointestinal tract. Cancer Res. 66 (2006) 3576-3583
    • (2006) Cancer Res. , vol.66 , pp. 3576-3583
    • Kucherlapati, M.H.1    Nguyen, A.A.2    Bronson, R.T.3    Kucherlapati, R.S.4
  • 27
    • 0037305849 scopus 로고    scopus 로고
    • Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system
    • MacPherson D., Sage J., Crowley D., Trumpp A., Bronson R.T., and Jacks T. Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system. Mol. Cell. Biol. 23 (2003) 1044-1053
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 1044-1053
    • MacPherson, D.1    Sage, J.2    Crowley, D.3    Trumpp, A.4    Bronson, R.T.5    Jacks, T.6
  • 29
    • 0036211680 scopus 로고    scopus 로고
    • Alterations in the INK4a/ARF locus and their effects on the growth of human osteosarcoma cell lines
    • Park Y.B., Park M.J., Kimura K., Shimizu K., Lee S.H., and Yokota J. Alterations in the INK4a/ARF locus and their effects on the growth of human osteosarcoma cell lines. Cancer Genet. Cytogenet. 133 (2002) 105-111
    • (2002) Cancer Genet. Cytogenet. , vol.133 , pp. 105-111
    • Park, Y.B.1    Park, M.J.2    Kimura, K.3    Shimizu, K.4    Lee, S.H.5    Yokota, J.6
  • 31
    • 4444373699 scopus 로고    scopus 로고
    • Analysis of cell cycle by flow cytometry
    • Pozarowski P., and Darzynkiewicz Z. Analysis of cell cycle by flow cytometry. Methods Mol. Biol. 281 (2004) 301-311
    • (2004) Methods Mol. Biol. , vol.281 , pp. 301-311
    • Pozarowski, P.1    Darzynkiewicz, Z.2
  • 32
    • 3042813439 scopus 로고    scopus 로고
    • Unique and overlapping functions of pRb and p107 in the control of proliferation and differentiation in epidermis
    • Ruiz S., Santos M., Segrelles C., Leis H., Jorcano J.L., Berns A., Paramio J.M., and Vooijs M. Unique and overlapping functions of pRb and p107 in the control of proliferation and differentiation in epidermis. Development 131 (2004) 2737-2748
    • (2004) Development , vol.131 , pp. 2737-2748
    • Ruiz, S.1    Santos, M.2    Segrelles, C.3    Leis, H.4    Jorcano, J.L.5    Berns, A.6    Paramio, J.M.7    Vooijs, M.8
  • 34
    • 0001510491 scopus 로고    scopus 로고
    • The RB and p53 pathways in cancer
    • Sherr C.J., and McCormick F. The RB and p53 pathways in cancer. Cancer Cell 2 (2002) 103-112
    • (2002) Cancer Cell , vol.2 , pp. 103-112
    • Sherr, C.J.1    McCormick, F.2
  • 35
    • 24944560377 scopus 로고    scopus 로고
    • A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells
    • Stegmeier F., Hu G., Rickles R.J., Hannon G.J., and Elledge S.J. A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells. Proc. Natl. Acad. Sci. USA 102 (2005) 13212-13217
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 13212-13217
    • Stegmeier, F.1    Hu, G.2    Rickles, R.J.3    Hannon, G.J.4    Elledge, S.J.5
  • 36
    • 0034840594 scopus 로고    scopus 로고
    • The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation
    • Thomas D.M., Carty S.A., Piscopo D.M., Lee J.S., Wang W.F., Forrester W.C., and Hinds P.W. The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation. Mol. Cell 8 (2001) 303-316
    • (2001) Mol. Cell , vol.8 , pp. 303-316
    • Thomas, D.M.1    Carty, S.A.2    Piscopo, D.M.3    Lee, J.S.4    Wang, W.F.5    Forrester, W.C.6    Hinds, P.W.7
  • 38
    • 35748930599 scopus 로고    scopus 로고
    • The retinoblastoma protein, RB, is required for gastrointestinal endocrine cells to exit the cell cycle, but not for hormone expression
    • Wang Y., Ray S.K., Hinds P.W., and Leiter A.B. The retinoblastoma protein, RB, is required for gastrointestinal endocrine cells to exit the cell cycle, but not for hormone expression. Dev. Biol. 311 (2007) 478-486
    • (2007) Dev. Biol. , vol.311 , pp. 478-486
    • Wang, Y.1    Ray, S.K.2    Hinds, P.W.3    Leiter, A.B.4
  • 40
    • 4644257541 scopus 로고    scopus 로고
    • Rb family proteins differentially regulate distinct cell lineages during epithelial development
    • Wikenheiser-Brokamp K.A. Rb family proteins differentially regulate distinct cell lineages during epithelial development. Development 131 (2004) 4299-4310
    • (2004) Development , vol.131 , pp. 4299-4310
    • Wikenheiser-Brokamp, K.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.