Obesity and nutrient sensing TOR pathway in flies and vertebrates: Functional conservation of genetic mechanisms

Trends in Endocrinology and Metabolism

Volumn 22, Issue 2, 2011, Pages 45-52

  Oldham, Sean ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; INSULIN LIKE PEPTIDE; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE; LIPID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SOMATOMEDIN C; STEROL REGULATORY ELEMENT BINDING PROTEIN; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR FOXO; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; BIOGENESIS; BIOSENSOR; CARDIOVASCULAR EFFECT; CELL FUNCTION; CELL GROWTH; DISEASE COURSE; DROSOPHILA; DYSLIPIDEMIA; GENETIC CONSERVATION; GENETIC MODEL; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; HEART DISEASE; HEART FUNCTION; HYPERGLYCEMIA; HYPOGLYCEMIA; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIFESPAN; LIPID DIET; LIPID METABOLISM; LIPID STORAGE; LIPOTOXICITY; MITOCHONDRION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; VERTEBRATE;

ANIMALS; BIOLOGICAL EVOLUTION; DIABETES MELLITUS, TYPE 2; DIETARY FATS; DROSOPHILA; HEART DISEASES; HUMANS; INSULIN; LIPID METABOLISM; LONGEVITY; MITOCHONDRIA; MODELS, BIOLOGICAL; OBESITY; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 79251646185     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tem.2010.11.002     Document Type: Review

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