Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium

PLoS Pathogens

Volumn 6, Issue 11, 2010, Pages

  Slater, Louise ^a,b,c   Bartlett, Nathan W ^a,b,c   Haas, Jennifer J ^a,b,c   Zhu, Jie ^a   Message, Simon D ^a,d   Walton, Ross P ^a,b,c   Sykes, Annemarie ^a,b,c,d   Dahdaleh, Samer ^a   Clarke, Deborah L ^a,c   Belvisi, Maria G ^a,c   Kon, Onn M ^c,d   Fujita, Takashi ^e   Jeffery, Peter K ^a   Johnston, Sebastian L ^a,b,c,d   Edwards, Michael R ^a,b,c  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c Centre for Respiratory Infections   (United Kingdom)

^d IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

^e KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CYTOKINE; GAMMA INTERFERON; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5 PROTEIN; MESSENGER RNA; PLASMID DNA; RETINOIC ACID INDUCIBLE PROTEIN I; RNA HELICASE; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; UNCLASSIFIED DRUG; ALPHA BETA INTERFERON RECEPTOR; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; DOUBLE STRANDED RNA; IFIH1 PROTEIN, HUMAN; IFNAR1 PROTEIN, MOUSE; TLR3 PROTEIN, HUMAN; VIRUS RNA;

ANIMAL TISSUE; ARTICLE; BRONCHUS MUCOSA; CELL CULTURE; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM; MOUSE; NONHUMAN; RHINOVIRUS INFECTION; RNA EXTRACTION; VIRUS REPLICATION; ANIMAL; BRONCHUS; DRUG ANTAGONISM; EPITHELIUM; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HELA CELL; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MOUSE MUTANT; PATHOGENICITY; PHYSIOLOGY; PICORNAVIRUS INFECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHINOVIRUS; VIROLOGY; WESTERN BLOTTING;

MUS; RHINOVIRUS;

ANIMALS; BLOTTING, WESTERN; BRONCHI; CELLS, CULTURED; DEAD-BOX RNA HELICASES; EPITHELIUM; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HELA CELLS; HUMANS; IMMUNITY, INNATE; MICE; MICE, KNOCKOUT; PICORNAVIRIDAE INFECTIONS; RECEPTOR, INTERFERON ALPHA-BETA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHINOVIRUS; RNA, DOUBLE-STRANDED; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA, VIRAL; TOLL-LIKE RECEPTOR 3;

EID: 79251492014     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1001178     Document Type: Article

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