The TAK1-JNK cascade is required for IRF3 function in the innate immune response

Cell Research

Volumn 19, Issue 4, 2009, Pages 412-428

  Zhang, Bianhong ^a   Li, Meng ^a   Chen, Liang ^a   Yang, Kai ^a   Shan, Yufei ^a   Zhu, Lianhui ^a   Sun, Shaogang ^a   Li, Lin ^a   Wang, Chen ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Innate immunity; IRF3; JNK; TAK1

Indexed keywords

ANTHRA(1,9 CD)PYRAZOL 6(2H) ONE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; INTERFERON REGULATORY FACTOR 3; IRF3 PROTEIN, HUMAN; LIPOPOLYSACCHARIDE; MUTANT PROTEIN; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TBK1 PROTEIN, HUMAN;

AMINO ACID SUBSTITUTION; ANIMAL; ARTICLE; CELL LINE; CHEMISTRY; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; HUMAN; INNATE IMMUNITY; METABOLISM; MOUSE; SIGNAL TRANSDUCTION;

AMINO ACID SUBSTITUTION; ANIMALS; ANTHRACENES; CELL LINE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMMUNITY, INNATE; INTERFERON REGULATORY FACTOR-3; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MICE; MUTANT PROTEINS; POLY I-C; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING;

BACTERIA (MICROORGANISMS);

EID: 64149123275     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2009.8     Document Type: Article

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