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Volumn 650, Issue , 2010, Pages 15-25

A brief introduction to RNAi and microRNAs in stem cells

Author keywords

gene regulation; miRNA; RNAi; siRNA; stem cell

Indexed keywords

MICRORNA;

EID: 78650513539     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-60761-769-3_2     Document Type: Review
Times cited : (7)

References (103)
  • 1
    • 0001359591 scopus 로고
    • Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans
    • Napoli, C., Lemieux, C., and Jorgensen, R. (1990) Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans. Plant Cell 2, 279-289.
    • (1990) Plant Cell , vol.2 , pp. 279-289
    • Napoli, C.1    Lemieux, C.2    Jorgensen, R.3
  • 2
    • 0026441194 scopus 로고
    • Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences
    • Romano, N., and Macino, G. (1992) Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences. Mol Microbiol 6, 3343-3353.
    • (1992) Mol Microbiol , vol.6 , pp. 3343-3353
    • Romano, N.1    Macino, G.2
  • 3
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon, G. J. (2002) RNA interference. Nature 418, 244-251.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 4
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., and Mello, C. C. (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 5
    • 0035856381 scopus 로고    scopus 로고
    • Short 5-phosphorylated double-stranded RNAs induce RNA interference in Drosophila
    • Boutla, A., Delidakis, C., Livadaras, I., Tsagris, M., and Tabler, M. (2001) Short 5-phosphorylated double-stranded RNAs induce RNA interference in Drosophila. Curr Biol 11, 1776-1780.
    • (2001) Curr Biol , vol.11 , pp. 1776-1780
    • Boutla, A.1    Delidakis, C.2    Livadaras, I.3    Tsagris, M.4    Tabler, M.5
  • 6
    • 0032443021 scopus 로고    scopus 로고
    • Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway
    • Kennerdell, J. R., and Carthew, R. W. (1998) Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway. Cell 95, 1017-1026.
    • (1998) Cell , vol.95 , pp. 1017-1026
    • Kennerdell, J.R.1    Carthew, R.W.2
  • 7
    • 1642400103 scopus 로고    scopus 로고
    • RNA interference: A practical approach
    • Duxbury, M. S., and Whang, E. E. (2004) RNA interference: A practical approach. J Surg Res 117, 339-344.
    • (2004) J Surg Res , vol.117 , pp. 339-344
    • Duxbury, M.S.1    Whang, E.E.2
  • 8
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., and Tuschl, T. (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 9
    • 33846120686 scopus 로고    scopus 로고
    • Establishing efficient siRNA knockdown in mouse embryonic stem cells
    • Chen, S., Choo, A.,Wang, N. D., Too, H. P., and Oh, S. K. (2007) Establishing efficient siRNA knockdown in mouse embryonic stem cells. Biotechnol Lett 29, 261-265.
    • (2007) Biotechnol Lett , vol.29 , pp. 261-265
    • Chen, S.1    Choo A.Wang, N.D.2    Too, H.P.3    Oh, S.K.4
  • 10
    • 0038343499 scopus 로고    scopus 로고
    • MicroRNA pathways in flies and worms: Growth, death, fat, stress, and timing
    • Ambros, V. (2003) MicroRNA pathways in flies and worms: Growth, death, fat, stress, and timing. Cell 113, 673-676.
    • (2003) Cell , vol.113 , pp. 673-676
    • Ambros, V.1
  • 11
    • 0037213225 scopus 로고    scopus 로고
    • RNA interference: Traveling in the cell and gaining functions?
    • Cerutti, H. (2003) RNA interference: Traveling in the cell and gaining functions?, Trends Genet 19, 39-46.
    • (2003) Trends Genet , vol.19 , pp. 39-46
    • Cerutti, H.1
  • 12
    • 0037213559 scopus 로고    scopus 로고
    • Mammalian RNAi for the masses
    • Shi, Y. (2003) Mammalian RNAi for the masses. Trends Genet 19, 9-12.
    • (2003) Trends Genet , vol.19 , pp. 9-12
    • Shi, Y.1
  • 13
    • 0036788304 scopus 로고    scopus 로고
    • Gene silencing in mammals by small interfering RNAs
    • McManus, M. T., and Sharp, P. A. (2002) Gene silencing in mammals by small interfering RNAs. Nat Rev Genet 3, 737-747.
    • (2002) Nat Rev Genet , vol.3 , pp. 737-747
    • McManus, M.T.1    Sharp, P.A.2
  • 14
    • 0038299558 scopus 로고    scopus 로고
    • Role of microRNAs in plant and animal development
    • Carrington, J. C., and Ambros, V. (2003) Role of microRNAs in plant and animal development. Science 301, 336-338.
    • (2003) Science , vol.301 , pp. 336-338
    • Carrington, J.C.1    Ambros, V.2
  • 15
    • 0242266618 scopus 로고    scopus 로고
    • The microRNA-producing enzyme Dicer1 is essential for zebrafish development
    • Wienholds, E., Koudijs, M. J., van Eeden, F. J., Cuppen, E., and Plasterk, R. H. (2003) The microRNA-producing enzyme Dicer1 is essential for zebrafish development. Nat Genet 35, 217-218.
    • (2003) Nat Genet , vol.35 , pp. 217-218
    • Wienholds, E.1    Koudijs, M.J.2    Van Eeden, F.J.3    Cuppen, E.4    Plasterk, R.H.5
  • 16
    • 33845755467 scopus 로고    scopus 로고
    • Illuminating the silence: Understanding the structure and function of small RNAs
    • Rana, T. M. (2007) Illuminating the silence: Understanding the structure and function of small RNAs. Nat Rev 8, 23-36.
    • (2007) Nat Rev , vol.8 , pp. 23-36
    • Rana, T.M.1
  • 17
    • 0034737818 scopus 로고    scopus 로고
    • Molecular biology. RNA interference
    • Sharp, P. A., and Zamore, P. D. (2000) Molecular biology. RNA interference. Science 287, 2431-2433.
    • (2000) Science , vol.287 , pp. 2431-2433
    • Sharp, P.A.1    Zamore, P.D.2
  • 18
    • 0035839109 scopus 로고    scopus 로고
    • Argonaute2, a link between genetic and biochemical analyses of RNAi
    • Hammond, S. M., Boettcher, S., Caudy, A. A., Kobayashi, R., and Hannon, G. J. (2001) Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 293, 1146-1150.
    • (2001) Science , vol.293 , pp. 1146-1150
    • Hammond, S.M.1    Boettcher, S.2    Caudy, A.A.3    Kobayashi, R.4    Hannon, G.J.5
  • 19
    • 4644223259 scopus 로고    scopus 로고
    • Mechanisms of gene silencing by double-stranded RNA
    • Meister, G., and Tuschl, T. (2004) Mechanisms of gene silencing by double-stranded RNA. Nature 431, 343-349.
    • (2004) Nature , vol.431 , pp. 343-349
    • Meister, G.1    Tuschl, T.2
  • 20
    • 0036791671 scopus 로고    scopus 로고
    • A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins
    • Ishizuka, A., Siomi, M. C., and Siomi, H. (2002) A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes Dev 16, 2497-2508.
    • (2002) Genes Dev , vol.16 , pp. 2497-2508
    • Ishizuka, A.1    Siomi, M.C.2    Siomi, H.3
  • 23
    • 0037320941 scopus 로고    scopus 로고
    • Numerous microRNPs in neuronal cells containing novel microRNAs
    • Dostie, J., Mourelatos, Z., Yang, M., Sharma, A., and Dreyfuss, G. (2003) Numerous microRNPs in neuronal cells containing novel microRNAs. RNA 9, 180-186.
    • (2003) RNA , vol.9 , pp. 180-186
    • Dostie, J.1    Mourelatos, Z.2    Yang, M.3    Sharma, A.4    Dreyfuss, G.5
  • 24
    • 1242296375 scopus 로고    scopus 로고
    • MiRNP: MRNA association in polyribosomes in a human neuronal cell line
    • Nelson, P. T., Hatzigeorgiou, A. G., and Mourelatos, Z. (2004) miRNP: MRNA association in polyribosomes in a human neuronal cell line. RNA 10, 387-394.
    • (2004) RNA , vol.10 , pp. 387-394
    • Nelson, P.T.1    Hatzigeorgiou, A.G.2    Mourelatos, Z.3
  • 26
    • 32544460452 scopus 로고    scopus 로고
    • The role of PACT in the RNA silencing pathway
    • Lee, Y., Hur, I., Park, S. Y., Kim, Y. K., Suh, M. R., and Kim, V. N. (2006) The role of PACT in the RNA silencing pathway. EMBO J 25, 522-532.
    • (2006) EMBO J , vol.25 , pp. 522-532
    • Lee, Y.1    Hur, I.2    Park, S.Y.3    Kim, Y.K.4    Suh, M.R.5    Kim, V.N.6
  • 27
    • 33745894330 scopus 로고    scopus 로고
    • Translation repression in human cells by microRNAinduced gene silencing requires RCK/p54
    • Chu, C. Y., and Rana, T. M. (2006) Translation repression in human cells by microRNAinduced gene silencing requires RCK/p54. PLoS Biol 4, e210.
    • (2006) PLoS Biol , vol.4
    • Chu, C.Y.1    Rana, T.M.2
  • 28
    • 0036828639 scopus 로고    scopus 로고
    • The Argonaute family: Tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis
    • Carmell, M. A., Xuan, Z., Zhang,M. Q., and Hannon, G. J. (2002) The Argonaute family: Tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis. Genes Dev 16, 2733-2742.
    • (2002) Genes Dev , vol.16 , pp. 2733-2742
    • Carmell, M.A.1    Xuan, Z.2    Zhang, M.Q.3    Hannon, G.J.4
  • 29
    • 0042124978 scopus 로고    scopus 로고
    • Identification of eight members of the Argonaute family in the human genome small
    • star, filled
    • Sasaki, T., Shiohama, A., Minoshima, S., and Shimizu, N. (2003) Identification of eight members of the Argonaute family in the human genome small star, filled. Genomics 82, 323-330.
    • (2003) Genomics , vol.82 , pp. 323-330
    • Sasaki, T.1    Shiohama, A.2    Minoshima, S.3    Shimizu, N.4
  • 30
    • 0037076320 scopus 로고    scopus 로고
    • ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos
    • Williams, R. W., and Rubin, G. M. (2002) ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos. Proc Natl Acad Sci USA 99, 6889-6894.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 6889-6894
    • Williams, R.W.1    Rubin, G.M.2
  • 31
    • 3142729150 scopus 로고    scopus 로고
    • Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways
    • Okamura, K., Ishizuka, A., Siomi, H., and Siomi, M. C. (2004) Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes Dev 18, 1655-1666.
    • (2004) Genes Dev , vol.18 , pp. 1655-1666
    • Okamura, K.1    Ishizuka, A.2    Siomi, H.3    Siomi, M.C.4
  • 32
    • 1642326115 scopus 로고    scopus 로고
    • RNA interference: A new mechanism by which FMRP acts in the normal brain? What can Drosophila teach us?
    • Siomi, H., Ishizuka, A., and Siomi, M. C. (2004) RNA interference: A new mechanism by which FMRP acts in the normal brain? What can Drosophila teach us?, Ment Retard Dev Disabil Res Rev 10, 68-74.
    • (2004) Ment Retard Dev Disabil Res Rev , vol.10 , pp. 68-74
    • Siomi, H.1    Ishizuka, A.2    Siomi, M.C.3
  • 33
    • 0036792769 scopus 로고    scopus 로고
    • Fragile Xrelated protein and VIG associate with the RNA interference machinery
    • Caudy, A. A., Myers, M., Hannon, G. J., and Hammond, S. M. (2002) Fragile Xrelated protein and VIG associate with the RNA interference machinery. Genes Dev 16, 2491-2496.
    • (2002) Genes Dev , vol.16 , pp. 2491-2496
    • Caudy, A.A.1    Myers, M.2    Hannon, G.J.3    Hammond, S.M.4
  • 34
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • Hammond, S. M., Bernstein, E., Beach, D., and Hannon, G. J. (2000) An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404, 293-296.
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 35
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir, S. M., Lendeckel, W., and Tuschl, T. (2001) RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 15, 188-200.
    • (2001) Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 36
    • 0037031576 scopus 로고    scopus 로고
    • Singlestranded antisense siRNAs guide target RNA cleavage in RNAi
    • Martinez, J., Patkaniowska, A., Urlaub, H., Luhrmann, R., and Tuschl, T. (2002) Singlestranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110, 563-574.
    • (2002) Cell , vol.110 , pp. 563-574
    • Martinez, J.1    Patkaniowska, A.2    Urlaub, H.3    Luhrmann, R.4    Tuschl, T.5
  • 37
    • 0035966319 scopus 로고    scopus 로고
    • MicroRNAs: Tiny regulators with great potential
    • Ambros, V. (2001) MicroRNAs: Tiny regulators with great potential. Cell 107, 823-826.
    • (2001) Cell , vol.107 , pp. 823-826
    • Ambros, V.1
  • 38
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros, V. (2004) The functions of animal microRNAs. Nature 431, 350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 39
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel, D. P. (2004) MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 116, 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 40
    • 0038299558 scopus 로고    scopus 로고
    • Role of microRNAs in plant and animal development
    • Carrington, J. C., and Ambros, V. (2003) Role of microRNAs in plant and animal development. Science 301, 336-338.
    • (2003) Science , vol.301 , pp. 336-338
    • Carrington, J.C.1    Ambros, V.2
  • 41
    • 67449088149 scopus 로고    scopus 로고
    • Large-scale genome analysis reveals unique features of microRNAs
    • Zhang, B. H., Stellwag, E. J., and Pan, X. P. (2009) Large-scale genome analysis reveals unique features of microRNAs. Gene 443, 100-109.
    • (2009) Gene , vol.443 , pp. 100-109
    • Zhang, B.H.1    Stellwag, E.J.2    Pan, X.P.3
  • 42
    • 33749984008 scopus 로고    scopus 로고
    • Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing
    • Yeom, K. H., Lee, Y., Han, J., Suh, M. R., and Kim, V. N. (2006) Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing. Nucleic Acids Res 34, 4622-4629.
    • (2006) Nucleic Acids Res , vol.34 , pp. 4622-4629
    • Yeom, K.H.1    Lee, Y.2    Han, J.3    Suh, M.R.4    Kim, V.N.5
  • 44
    • 27744537851 scopus 로고    scopus 로고
    • Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
    • Gregory, R. I., Chendrimada, T. P., Cooch, N., and Shiekhattar, R. (2005) Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 123, 631-640.
    • (2005) Cell , vol.123 , pp. 631-640
    • Gregory, R.I.1    Chendrimada, T.P.2    Cooch, N.3    Shiekhattar, R.4
  • 45
    • 33749047034 scopus 로고    scopus 로고
    • MicroRNA biogenesis: Isolation and characterization of the microprocessor complex
    • Gregory, R. I., Chendrimada, T. P., and Shiekhattar, R. (2006) MicroRNA biogenesis: Isolation and characterization of the microprocessor complex. Methods Mol Biol 342, 33-47.
    • (2006) Methods Mol Biol , vol.342 , pp. 33-47
    • Gregory, R.I.1    Chendrimada, T.P.2    Shiekhattar, R.3
  • 46
    • 33845809231 scopus 로고    scopus 로고
    • P bodies: At the crossroads of post-transcriptional pathways
    • Eulalio, A., Behm-Ansmant, I., and Izaurralde, E. (2007) P bodies: At the crossroads of post-transcriptional pathways. Nat Reviews 8, 9-22.
    • (2007) Nat Reviews , vol.8 , pp. 9-22
    • Eulalio, A.1    Behm-Ansmant, I.2    Izaurralde, E.3
  • 47
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee, R. C., Feinbaum, R. L., and Ambros, V. (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 48
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene Lin-14 by Lin-4 mediates temporal pattern-formation in C. elegans
    • Wightman, B., Ha, I., and Ruvkun, G. (1993) Posttranscriptional regulation of the heterochronic gene Lin-14 by Lin-4 mediates temporal pattern-formation in C. elegans. Cell 75, 855-862.
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 49
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee, R. C., and Ambros, V. (2001) An extensive class of small RNAs in Caenorhabditis elegans. Science 294, 862-864.
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 50
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana, M., Rauhut, R., Lendeckel, W., and Tuschl, T. (2001) Identification of novel genes coding for small expressed RNAs. Science 294, 853-858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 51
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau, N. C., Lim, L. P., Weinstein, E. G., and Bartel, D. P. (2001) An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294, 858-862.
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 54
    • 0037418839 scopus 로고    scopus 로고
    • bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila
    • Brennecke, J., Hipfner, D. R., Stark, A., Russell, R. B., and Cohen, S. M. (2003) bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 113, 25-36.
    • (2003) Cell , vol.113 , pp. 25-36
    • Brennecke, J.1    Hipfner, D.R.2    Stark, A.3    Russell, R.B.4    Cohen, S.M.5
  • 55
    • 0037694970 scopus 로고    scopus 로고
    • The Drosophila microRNA Mir-14 suppresses cell death and is required for normal fat metabolism
    • Xu, P., Vernooy, S. Y., Guo, M., and Hay, B. A. (2003) The Drosophila microRNA Mir-14 suppresses cell death and is required for normal fat metabolism. Curr Biol 13, 790-795.
    • (2003) Curr Biol , vol.13 , pp. 790-795
    • Xu, P.1    Vernooy, S.Y.2    Guo, M.3    Hay, B.A.4
  • 57
    • 65549120766 scopus 로고    scopus 로고
    • Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7
    • Webster, R. J., Giles, K. M., Price, K. J., Zhang, P. M., Mattick, J. S., and Leedman, P. J. (2009) Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7. J Biol Chem 284, 5731-5741.
    • (2009) J Biol Chem , vol.284 , pp. 5731-5741
    • Webster, R.J.1    Giles, K.M.2    Price, K.J.3    Zhang, P.M.4    Mattick, J.S.5    Leedman, P.J.6
  • 58
    • 33846188098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • Zhang, B. H., Pan, X. P., Cobb, G. P., and Anderson, T. A. (2007) MicroRNAs as oncogenes and tumor suppressors. Dev Biol 302, 1-12.
    • (2007) Dev Biol , vol.302 , pp. 1-12
    • Zhang, B.H.1    Pan, X.P.2    Cobb, G.P.3    Anderson, T.A.4
  • 59
    • 33744805399 scopus 로고    scopus 로고
    • Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatinmodifying drugs in human cancer cells
    • Saito, Y., Liang, G., Egger, G., Friedman, J. M., Chuang, J. C., Coetzee, G. A., and Jones, P. A. (2006) Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatinmodifying drugs in human cancer cells. Cancer Cell 9, 435-443.
    • (2006) Cancer Cell , vol.9 , pp. 435-443
    • Saito, Y.1    Liang, G.2    Egger, G.3    Friedman, J.M.4    Chuang, J.C.5    Coetzee, G.A.6    Jones, P.A.7
  • 60
    • 28944438404 scopus 로고    scopus 로고
    • Modulating Hox gene functions during animal body patterning
    • Pearson, J. C., Lemons, D., and McGinnis, W
    • Pearson, J. C., Lemons, D., and McGinnis, W. (2005) Modulating Hox gene functions during animal body patterning. Nat Rev Genet 6, 893-904.
    • (2005) Nat Rev Genet , vol.6 , pp. 893-904
  • 61
    • 30644475098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes
    • Hammond, S. M. (2006) MicroRNAs as oncogenes. Curr Opin Genet Dev 16, 4-9.
    • (2006) Curr Opin Genet Dev , vol.16 , pp. 4-9
    • Hammond, S.M.1
  • 62
    • 30644475098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes
    • Hammond, S. M. (2006) MicroRNAs as oncogenes. Curr Opin Genet Dev 16, 4-9.
    • (2006) Curr Opin Genet Dev , vol.16 , pp. 4-9
    • Hammond, S.M.1
  • 63
    • 33751254116 scopus 로고    scopus 로고
    • The neuronal microRNA system
    • Kosik, K. S. (2006) The neuronal microRNA system. Nat Rev Neurosci 7, 911-920.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 911-920
    • Kosik, K.S.1
  • 65
    • 0141631876 scopus 로고    scopus 로고
    • A microRNA array reveals extensive regulation of microRNAs during brain development
    • Krichevsky, A. M., King, K. S., Donahue, C. P., Khrapko, K., and Kosik, K. S. (2003) A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 9, 1274-1281.
    • (2003) RNA , vol.9 , pp. 1274-1281
    • Krichevsky, A.M.1    King, K.S.2    Donahue, C.P.3    Khrapko, K.4    Kosik, K.S.5
  • 68
    • 1942494040 scopus 로고    scopus 로고
    • Expression profiling of mammalian microRNAs uncovers a subset of brainexpressed microRNAs with possible roles in murine and human neuronal differentiation
    • Sempere, L. F., Freemantle, S., Pitha-Rowe, I., Moss, E., Dmitrovsky, E., and Ambros, V. (2004) Expression profiling of mammalian microRNAs uncovers a subset of brainexpressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol 5, R13.
    • (2004) Genome Biol , vol.5
    • Sempere, L.F.1    Freemantle, S.2    Pitha-Rowe, I.3    Moss, E.4    Dmitrovsky, E.5    Ambros, V.6
  • 69
    • 33749064940 scopus 로고    scopus 로고
    • A trace of silence: Memory and microRNA at the synapse
    • Ashraf, S. I., and Kunes, S. (2006) A trace of silence: Memory and microRNA at the synapse. Curr Opin Neurobiol 16, 535-539.
    • (2006) Curr Opin Neurobiol , vol.16 , pp. 535-539
    • Ashraf, S.I.1    Kunes, S.2
  • 70
    • 33749236251 scopus 로고    scopus 로고
    • MicroRNA: A new player in stem cells
    • Zhang, B. H., Pan, X. P., and Anderson, T. A. (2006) MicroRNA: A new player in stem cells. J Cell Physiol 209, 266-269.
    • (2006) J Cell Physiol , vol.209 , pp. 266-269
    • Zhang, B.H.1    Pan, X.P.2    Anderson, T.A.3
  • 71
    • 22744433240 scopus 로고    scopus 로고
    • Normal microRNA maturation and germ-line stem cell maintenance requires loquacious, a double-stranded RNA- binding domain protein
    • Forstemann, K., Tomari, Y., Du, T. T., Vagin, V. V., Denli, A. M., Bratu, D. P., Klattenhoff, C., Theurkauf, W. E., and Zamore, P. D. (2005) Normal microRNA maturation and germ-line stem cell maintenance requires loquacious, a double-stranded RNA- binding domain protein. PLoS Biol 3, 1187-1201.
    • (2005) PLoS Biol , vol.3 , pp. 1187-1201
    • Forstemann, K.1    Tomari, Y.2    Du, T.T.3    Vagin, V.V.4    Denli, A.M.5    Bratu, D.P.6    Klattenhoff, C.7    Theurkauf, W.E.8    Zamore, P.D.9
  • 72
    • 58849163959 scopus 로고    scopus 로고
    • MicroRNAs: Key regulators of stem cells
    • Gangaraju, V. K., and Lin, H. F. (2009) MicroRNAs: Key regulators of stem cells. Nat Rev Mol Cell Biol 10, 116-125.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 116-125
    • Gangaraju, V.K.1    Lin, H.F.2
  • 73
    • 34848897853 scopus 로고    scopus 로고
    • MicroRNAs regulate synthesis of the neurotransmitter substance P in human mesenchymal stem cell-derived neuronal cells
    • Greco, S. J., and Rameshwar, P. (2007) microRNAs regulate synthesis of the neurotransmitter substance P in human mesenchymal stem cell-derived neuronal cells. Proc Natl Acad Sci USA 104, 15484-15489.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15484-15489
    • Greco, S.J.1    Rameshwar, P.2
  • 74
    • 57149133671 scopus 로고    scopus 로고
    • HMGA2, microRNAs, and stem cell aging
    • Hammond, S. M., and Sharpless, N. E. (2008) HMGA2, microRNAs, and stem cell aging. Cell 135, 1013-1016.
    • (2008) Cell , vol.135 , pp. 1013-1016
    • Hammond, S.M.1    Sharpless, N.E.2
  • 75
  • 77
    • 0042442335 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs
    • Houbaviy, H. B., Murray, M. F., and Sharp, P. A. (2003) Embryonic stem cell-specific microRNAs. Dev Cell 5, 351-358.
    • (2003) Dev Cell , vol.5 , pp. 351-358
    • Houbaviy, H.B.1    Murray, M.F.2    Sharp, P.A.3
  • 80
    • 33745480963 scopus 로고    scopus 로고
    • Specific microRNAs modulate embryonic stem cell-derived neurogenesis
    • Krichevsky, A. M., Sonntag, K. C., Isacson, O., and Kosik, K. S. (2006) Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells 24, 857-864.
    • (2006) Stem Cells , vol.24 , pp. 857-864
    • Krichevsky, A.M.1    Sonntag, K.C.2    Isacson, O.3    Kosik, K.S.4
  • 81
    • 1642603947 scopus 로고    scopus 로고
    • A small modulatory dsRNA specifies the fate of adult neural stem cells
    • Kuwabara, T., Hsieh, J., Nakashima, K., Taira, K., and Gage, F. H. (2004) A small modulatory dsRNA specifies the fate of adult neural stem cells. Cell 116, 779-793.
    • (2004) Cell , vol.116 , pp. 779-793
    • Kuwabara, T.1    Hsieh, J.2    Nakashima, K.3    Taira, K.4    Gage, F.H.5
  • 82
  • 83
    • 39749162835 scopus 로고    scopus 로고
    • MicroRNA regulation of stem cell fate
    • Li, Q. T., and Gregory, R. I. (2008) microRNA regulation of stem cell fate. Cell Stem Cell 2, 195-196.
    • (2008) Cell Stem Cell , vol.2 , pp. 195-196
    • Li, Q.T.1    Gregory, R.I.2
  • 85
    • 33947107476 scopus 로고    scopus 로고
    • The miRNA pathway intrinsically controls self-renewal of Drosophila germline stem cells
    • Park, J. K., Liu, X., Strauss, T. J., McKearin, D. M., and Liu, Q. H. (2007) The miRNA pathway intrinsically controls self-renewal of Drosophila germline stem cells. Curr Biol 17, 533-538.
    • (2007) Curr Biol , vol.17 , pp. 533-538
    • Park, J.K.1    Liu, X.2    Strauss, T.J.3    McKearin, D.M.4    Liu, Q.H.5
  • 88
    • 56749091922 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation
    • Wang, Y., Baskerville, S., Shenoy, A., Babiarz, J. E., Baehner, L., and Blelloch, R. (2008) Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat Genet 40, 1478-1483.
    • (2008) Nat Genet , vol.40 , pp. 1478-1483
    • Wang, Y.1    Baskerville, S.2    Shenoy, A.3    Babiarz, J.E.4    Baehner, L.5    Blelloch, R.6
  • 90
    • 14944352046 scopus 로고    scopus 로고
    • Application of RNA interference to study stem cell function: Current status and future perspectives
    • Zou, G. M., and Yoder, M. C. (2005) Application of RNA interference to study stem cell function: Current status and future perspectives. Biol Cell 97, 211-219.
    • (2005) Biol Cell , vol.97 , pp. 211-219
    • Zou, G.M.1    Yoder, M.C.2
  • 94
    • 33847323881 scopus 로고    scopus 로고
    • DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal
    • Wang, Y., Medvid, R., Melton, C., Jaenisch, R., and Blelloch, R. (2007) DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet 39, 380-385.
    • (2007) Nat Genet , vol.39 , pp. 380-385
    • Wang, Y.1    Medvid, R.2    Melton, C.3    Jaenisch, R.4    Blelloch, R.5
  • 95
    • 39749110083 scopus 로고    scopus 로고
    • Small noncoding RNAs in animal development
    • Stefani, G., and Slack, F. J. (2008) Small noncoding RNAs in animal development. Nat Rev 9, 219-230.
    • (2008) Nat Rev , vol.9 , pp. 219-230
    • Stefani, G.1    Slack, F.J.2
  • 97
    • 0141953309 scopus 로고    scopus 로고
    • Oct4 RNA interference induces trophectoderm differentiation in mouse embryonic stem cells
    • Velkey, J. M., and O'Shea, K. S. (2003) Oct4 RNA interference induces trophectoderm differentiation in mouse embryonic stem cells. Genesis 37, 18-24.
    • (2003) Genesis , vol.37 , pp. 18-24
    • Velkey, J.M.1    O'Shea, K.S.2
  • 98
    • 1442311693 scopus 로고    scopus 로고
    • Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells
    • Hay, D. C., Sutherland, L., Clark, J., and Burdon, T. (2004) Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells. Stem Cells 22, 225-235.
    • (2004) Stem Cells , vol.22 , pp. 225-235
    • Hay, D.C.1    Sutherland, L.2    Clark, J.3    Burdon, T.4
  • 99
    • 0034683099 scopus 로고    scopus 로고
    • Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target
    • Ui-Tei, K., Zenno, S., Miyata, Y., and Saigo, K. (2000) Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target. FEBS Lett 479, 79-82.
    • (2000) FEBS Lett , vol.479 , pp. 79-82
    • Ui-Tei, K.1    Zenno, S.2    Miyata, Y.3    Saigo, K.4
  • 100
    • 0034084338 scopus 로고    scopus 로고
    • Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): Mechanism of action
    • Gil, J., and Esteban, M. (2000) Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): Mechanism of action. Apoptosis 5, 107-114.
    • (2000) Apoptosis , vol.5 , pp. 107-114
    • Gil, J.1    Esteban, M.2
  • 101
    • 1342268939 scopus 로고    scopus 로고
    • Short interfering RNA (siRNA)-mediated RNA interference (RNAi) in human cells
    • Caplen, N. J., and Mousses, S. (2003) Short interfering RNA (siRNA)-mediated RNA interference (RNAi) in human cells. Ann N Y Acad Sci 1002, 56-62.
    • (2003) Ann N Y Acad Sci , vol.1002 , pp. 56-62
    • Caplen, N.J.1    Mousses, S.2
  • 102
    • 0037439945 scopus 로고    scopus 로고
    • RNAi reveals anti-apoptotic and transcriptionally repressive activities of DAXX
    • Michaelson, J. S., and Leder, P. (2003) RNAi reveals anti-apoptotic and transcriptionally repressive activities of DAXX. J Cell Sci 116, 345-352.
    • (2003) J Cell Sci , vol.116 , pp. 345-352
    • Michaelson, J.S.1    Leder, P.2
  • 103
    • 0036726313 scopus 로고    scopus 로고
    • Stable suppression of tumorigenicity by virus-mediated RNA interference
    • Brummelkamp, T. R., Bernards, R., and Agami, R. (2002) Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2, 243-247.
    • (2002) Cancer Cell , vol.2 , pp. 243-247
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3


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