Nutrition concerns and health effects of vegetarian diets

Nutrition in Clinical Practice

Volumn 25, Issue 6, 2010, Pages 613-620

  Craig, Winston John ^a  

^a ANDREWS UNIVERSITY   (United States)

Author keywords

3; calcium; cancer; cardiovascular disease; diabetes; osteoporosis; research and diseases; vegan; vegetarian; vitamin B12; vitamin D

Indexed keywords

CALCIUM; CHOLESTEROL; CYANOCOBALAMIN; IRON; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OMEGA 3 FATTY ACID; SATURATED FATTY ACID; VITAMIN D; ZINC;

BLOOD PRESSURE; BODY MASS; CARDIOVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; DIETARY FIBER; FRUIT; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; LEGUME; MORTALITY; NEOPLASM; NON INSULIN DEPENDENT DIABETES MELLITUS; NUT; NUTRIENT; NUTRITION; OBESITY; OSTEOPOROSIS; REVIEW; SOYBEAN; VEGETABLE; VEGETARIAN DIET;

CARDIOVASCULAR DISEASES; DEFICIENCY DISEASES; DIABETES MELLITUS, TYPE 2; DIET, VEGETARIAN; HEALTH STATUS; HUMANS; NEOPLASMS;

EID: 78650459003     PISSN: 08845336     EISSN: None     Source Type: Journal    
DOI: 10.1177/0884533610385707     Document Type: Review

References (78)

1. Craig WJ Health effects of vegan diets. Am J Clin Nutr. 2009 ; 89: 1627S - 1633S.
2. Key TJ, Appleby PN, Rosell MS Health effects of vegetarian and vegan diets. Proc Nutr Soc. 2006 ; 65: 35-41.
3. Holick MF The vitamin D deficiency pandemic and consequences for nonskeletal health: mechanisms of action. Mol Aspects Med. 2008 ; 29: 361-368.
4. Holick MF, Chen TC Vitamin D. deficiency: a worldwide problem with health consequences. Am J Clin Nutr. 2008 ; 87: 1080S - 1086S.
5. Dunn-Emke SR, Weidner G., Pettenall EB, Marlin RO, Chi C., Ornish DM Nutrient adequacy of a very low-fat vegan diet. J Am Diet Assoc. 2005 ; 105: 1442-1446.
6. Messina V., Mangels R., Messina M. The Dietitian's Guide to Vegetarian Diets: Issues and Applications. 2 nd ed. Sudbury, Mass: Jones & Bartlett ; 2004.
7. Parsons TJ, van Dusseldorp M., van der Vliet M., van de Werken K., Schaafsma G., van Staveren WA Reduced bone mass in Dutch adolescents fed a macrobiotic diet in early life. J Bone Miner Res. 1997 ; 12: 1486-1494.
8. Holick MF, Biancuzzo RM, Chen TC, et al. Vitamin D2 is as effective as vitamin D3 in maintaining circulating concentrations of 25-hydroxyvitamin D. J Clin Endocrinol Metab. 2008 ; 93: 677-681.
9. Herrmann W., Schorr H., Purschwitz K., Rassoul F., Richter V. Total homocysteine, vitamin B12, and total antioxidant status in vegetarians. Clin Chem. 2001 ; 47: 1094-1101.
10. Rosell MS, Lloyd-Wright Zechariah, Appleby PN, Sanders TA, Allen NE, Key TJ Long-chain n-3 polyunsatuurated fatty acids in plasma in British meat-eating, vegetarian, and vegan men. Am J Clin Nutr. 2005 ; 82: 327-334.
11. Williams CM, Burdge G. Long-chain n-3 PUFA: plant v. marine sources. Proc Nutr Soc. 2006 ; 65: 42-50.
12. Conquer JA, Holub BJ Supplementation with an algae source of docosahexaenoic acid increases (n-3) fatty acid status and alters selected risk factors for heart disease in vegetarian subjects. J Nutr. 1996 ; 126: 3032-3039.
13. Weaver C., Proulx W., Heaney R. Choices for achieving adequate dietary calcium with a vegetarian diet. Am J Clin Nutr. 1999 ; 70 (suppl): 543S - 548S.
14. Zhao Y., Martin BR, Weaver CM Calcium bioavailability of calcium carbonate fortified soymilk is equivalent to cow's milk in young women. J Nutr. 2005 ; 135: 2379-2382.
15. Alexander D., Ball MJ, Mann J. Nutrient intake and haematological status of vegetarians and age-sex matched omnivores. Eur J Clin Nutr. 1994 ; 48: 538-546.
16. Hallberg L., Hulthen L. Prediction of dietary iron absorption: an algorithm for calculating absorption and bioavailability of dietary iron. Am J Clin Nutr. 2000 ; 71: 1147-1160.
17. Hunt JR, Roughead ZK Adaptation of iron absorption in men consuming diets with high or low iron bioavailability. Am J Clin Nutr. 2000 ; 71: 94-102.
18. Hunt JR Bioavailability of iron, zinc, and other trace minerals from vegetarian diets. Am J Clin Nutr. 2003 ; 78 (suppl): 633S - 639S.
19. Lonnerdal B. Dietary factors influencing zinc absorption. J Nutr. 2000 ; 130 (5S suppl): 1378S - 1383S.
20. Appleby PN, Davey GK, Key TJ Hypertension and blood pressure among meat eaters, fish eaters, vegetarians and vegans in EPIC-Oxford. Public Health Nutr. 2002 ; 5: 645-654.
21. Fraser GE Associations between diet and cancer, ischemic heart disease, and all-cause mortality in non-Hispanic white California Seventh-day Adventists. Am J Clin Nutr. 1999 ; 70 (3 suppl). 532S - 538S.
22. Key TJ, Fraser GE, Thorogood M., et al. Mortality in vegetarians and nonvegetarians: detailed findings from a collaborative analysis of 5 prospective studies. Am J Clin Nutr. 1999 ; 70 (3 suppl). 516S - 524S.
23. Kelly JH Jr, Sabaté J. Nuts and coronary heart disease: an epidemiological perspective. Br J Nutr. 2006 ; 96 (suppl 2). S61 - S67.
24. Katan MB, Grundy SM, Jones P., Law M., Miettinen T., Paoletti R. ; Stresa Workshop Participants. Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels. Mayo Clin Proc. 2003 ; 78: 965-978.
25. Joshipura KJ, Hu FB, Manson JE, et al. The effect of fruit and vegetable intake on risk for coronary heart disease. Ann Intern Med. 2001 ; 134: 1106-1114.
26. Djoussé L., Gaziano JM Breakfast cereals and risk of heart failure in the physicians' health study I. Arch Intern Med. 2007 ; 167: 2080-2085. (Pubitemid 350036707)
27. Sirtori CR, Eberini I., Arnoldi A. Hypocholesterolaemic effects of soya proteins: results of recent studies are predictable from the Anderson meta-analysis data. Br J Nutr. 2007 ; 97: 816-822.
28. Liu RH Health benefits of fruits and vegetables are from additive and synergistic combinations of phytochemicals. Am J Clin Nutr. 2003 ; 78 (suppl): 517S - 5120S.
29. Perez-Vizcaino F., Duarte J., Andriantsitohaina R. Endothelial function and cardiovascular disease: effects of quercetin and wine polyphenols. Free Radic Res. 2006 ; 40: 1054-1065.
30. Ornish D., Scherwitz LW, Billings JH, et al. Intensive lifestyle changes for reversal of coronary heart disease. JAMA. 1998 ; 280: 2001-2007.
31. Jenkins DJ, Kendall CW, Marchie A., et al. Direct comparison of a dietary portfolio of cholesterol-lowering foods with a statin in hypercholesterolemic participants. Am J Clin Nutr. 2005 ; 81: 380-387.
32. Toohey ML, Harris MA, DeWitt W., Foster G., Schmidt WD, Melby CL Cardiovascular disease risk factors are lower in African-American vegans compared with lacto-ovo-vegetarians. J Am Coll Nutr. 1998 ; 17: 425-434.
33. Berkow SE, Barnard ND Blood pressure regulation and vegetarian diets. Nutr Rev. 2005 ; 63: 1-8.
34. Sacks FM, Appel LJ, Moore TJ, et al. A dietary approach to prevent hypertension: a review of the Dietary Approaches to Stop Hypertension (DASH) study. Clin Cardiol. 1999 ; 22 (suppl 7). 1116-11110.
35. Appleby PN, Thorogood M., Mann JI, Key TJ The Oxford Vegetarian Study: an overview. Am J Clin Nutr. 1999 ; 70: 525S - 5231S.
36. Tonstad S., Butler T., Yan R., Fraser GE Type of vegetarian diet, body weight, and prevalence of type 2 diabetes. Diabetes Care. 2009 ; 32: 791-796.
37. Braithwaite N., Fraser HS, Modeste N., Broome H., King R. Obesity, diabetes, hypertension, and vegetarian status among Seventh-day Adventists in Barbados: preliminary results. Eth Dis. 2003 ; 13: 34-39.
38. Rosell M., Appleby P., Spencer E., Key T. Weight gain over 5 years in 21,966 meat-eating, fish-eating, vegetarian, and vegan men and women in EPIC-Oxford. Int J Obesity. 2006 ; 30: 1389-1396.
39. Vang A., Singh PN, Lee JW, Haddad EH Meats, processed meats, obesity, weight gain and occurrence of diabetes among adults: findings from the Adventist Health Studies. Ann Nutr Metab. 2008 ; 52: 96-104.
40. Song Y., Manson JE, Buring JE, Liu S. A prospective study of red meat consumption and type 2 diabetes in middle-aged and elderly women: the women's health study. Diabetes Care. 2004 ; 27: 2108-2115.
41. Fung TT, Schulze M., Manson JE, Willett WC, Hu FB Dietary patterns, meat intake, and the risk of type 2 diabetes in women. Arch Intern Med. 2004 ; 164: 2235-2240.
42. Jiang R., Manson JE, Stampfer MJ, Liu S., Willett WC, Hu FB Nut and peanut butter consumption and risk of type 2 diabetes in women. JAMA. 2002 ; 288: 2554-2560.
43. Villegas R., Gao YT, Yang G., et al. Legume and soy food intake and the incidence of type 2 diabetes in the Shanghai Women's Health Study. Am J Clin Nutr. 2008 ; 87: 162-167.
44. Venn BJ, Mann JI Cereal grains, legumes, and diabetes. Eur J Clin Nutr. 2004 ; 58: 1443-1461.
45. Bazzano LA, Li TY, Joshipura KJ, Hu FB Intake of fruit, vegetables, and fruit juices and risk of diabetes in women. Diabetes Care. 2008 ; 31: 1311-1317.
46. Barnard ND, Cohen J., Jenkins DJA, et al. A low-fat vegan diet improves glycemic control and cardiovascular risk factors in a randomized clinical trial in individuals with Type 2 Diabetes. Diabetes Care. 2006 ; 29: 1777-1783.
47. World Cancer Research Fund. Food, Nutrition, Physical Activity, and the Prevention of Cancer: A Global Perspective. Washington, DC: American Institute for Cancer Research ; 2007.
48. Taylor EF, Burley VJ, Greenwood DC, Cade JE Meat consumption and risk of breast cancer in the UK Women's Cohort Study. Br J Cancer. 2007 ; 96: 1139-1146.
49. Key TJ, Appleby PN, Spencer EA, Travis RC, Roddam AW, Allen NE Cancer incidence in vegetarians: results from the European Investigation into Cancer and Nutrition (EPIC-Oxford). Am J Clin Nutr. 2009 ; 89 (suppl): 1620S - 1626S.
50. Fraser GE Vegetarian diets: what do we know of their effects on common chronic diseases? Am J Clin Nutr. 2009 ; 89 (suppl): 1607S - 1612S.
51. Khan N., Afaq F., Mukhtar H. Cancer chemoprevention through dietary antioxidants: progress and promise. Antioxid Redox Signal. 2008 ; 10: 475-510.
52. Jacobs DR, Marquart L., Slavin J., Kushi LH Whole-grain intake and cancer: an expanded review and meta-analysis. Nutr Cancer. 1998 ; 30: 85-96. (Pubitemid 28217486)
53. Okarter N., Liu RH Health benefits of whole grain phytochemicals. Crit Rev Food Sci Nutr. 2010 ; 50: 193-208.
54. Pelucchi C., Bosetti C., Rossi M., Negri E., La Vecchia C. Selected aspects of Mediterranean diet and cancer risk. Nutr Cancer. 2009 ; 61: 756-766.
55. Bingham SA, Day NE, Luben R., et al. Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study. Lancet. 2003 ; 361: 1496-1501.
56. Wu AH, Yu MC, Tseng CC, Pike MC Epidemiology of soy exposures and breast cancer risk. Br J Cancer. 2008 ; 98: 9-14.
57. Shu XO, Zheng Y., Cai H., et al. Soy food intake and breast cancer survival. JAMA. 2009 ; 302: 2437-2443.
58. Liu RH Potential synergy of phytochemicals in cancer prevention: mechanism of action. J Nutr. 2004 ; 134 (12 suppl). 3479S - 3485S.
59. Key TJ, Appleby PN, Rosell MS Health effects of vegetarian and vegan diets. Proc Nutr Soc. 2006 ; 65: 35-41.
60. Missmer SA, Smith-Warner SA, Spiegelman D., et al. Meat and dairy food consumption and breast cancer: a pooled analysis of cohort studies. Int J Epidemiol. 2002 ; 31: 78-85.
61. Bessaoud F., Daurès JP, Gerber M. Dietary factors and breast cancer risk: a case control study among a population in Southern France. Nutr Cancer. 2008 ; 60: 177-187.
62. New SA Do vegetarians have a normal bone mass ? Osteporos Int. 2004 ; 15: 679-688.
63. Appleby P., Roddam A., Allen N., Key T. Comparative fracture risk in vegetarians and nonvegetarians in EPIC-Oxford. Eur J Clin Nutr. 2007 ; 61: 1400-1406.
64. Lau EMC, Kwok T., Woo J., Ho SC Bone mineral density in Chinese elderly female vegetarians, vegans, lacto-ovegetarians and omnivores. Eur J Clin Nutr. 1998 ; 52: 60-64.
65. Outila TA, Karkkainen MU, Seppanen RH, Lamberg-Allardt CJ Dietary intake of vitamin D in premenopausal, healthy vegans was insufficient to maintain concentrations of serum 25-hydroxyvitamin D and intact parathyroid hormone within normal ranges during the winter in Finland. J Am Diet Assoc. 2000 ; 100: 434-441.
66. Sellmeyer DE, Stone KL, Sebastian A., Cummings SR A high ratio of dietary animal to vegetable protein increases the rate of bone loss and the risk of fracture in postmenopausal women. Am J Clin Nutr. 2001 ; 73: 118-122.
67. Kerstetter JE, Svastisalee CM, Caseria DM, Mitnick ME, Insogna KL A threshold for low-protein diet-induced elevations in parathyroid hormone. Am J Clin Nutr. 2000 ; 72: 168-173.
68. Darling AL, Millward DJ, Torgerson, Hewitt CE, Lanham-New SA Dietary protein and bone health: a systematic review and meta-analysis. Am J Clin Nutr. 2009 ; 90: 1674-1692.
69. New SA Intake of fruit and vegetables: implications for bone health. Proc Nutr Soc. 2003 ; 62: 889-899.
70. New SA, Bolton-Smith C., Grubb DA, Reid DM Nutritional influences on mineral density: a cross-sectional study in premenopausal women. Am J Clin Nutr. 1997 ; 65: 1831-1839.
71. Booth SL, Tucker KL, Chen H., et al. Dietary vitamin K intakes are associated with hip fracture but not with bone mineral density in elderly men and women. Am J Clin Nutr. 2000 ; 71: 1201-1208.
72. Vergnaud P., Garnero P., Meunier PJ, Breart G., Kamihagi K., Delmas PD Undercarboxylated osteocalcin measured with a specific immunoassay predicts hip fracture in elderly women: the EPIDOS Study. J Clin Endocrinol Metab. 1997 ; 82: 719-724.
73. Ma DF, Qin LQ, Wang PY, Katoh R. Soy isoflavone intake inhibits bone resorption and stimulates bone formation in menopausal women: meta-analysis of randomized controlled trials. Eur J Clin Nutr. 2008 ; 62: 155-161.
74. Marini H., Minutoli L., Polito F., et al. Effects of the phytoestrogen genistein on bone metabolism in osteopenic postmenopausal women: a randomized trial. Ann Intern Med. 2007 ; 146: 839-847.
75. Fraser GE Risk factors and disease among vegans. In: Fraser GE, ed. Diet, Life Expectancy and Chronic Disease. New York, NY: Oxford University Press; 2003: 231-239.
76. Craig W. Going raw: a new trend. Veg Nutr Update. 2004 ;12: 1, 5, 6.
77. Donaldson MS Food and nutrient intake of Hallelujah vegetarians. Nutr Food Sci. 2001 ; 31: 293-303.
78. U.S. Department of Agriculture, Agricultural Research Service. USDA Nutrient Database for Standard Reference, Release 22, 2009. http://www.nal.usda. gov/fnic/foodcomp/search/. Accessed April 12, 2010.