Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease

Progress in Neurobiology

Volumn 93, Issue 1, 2011, Pages 99-110

  Salminen, Antero ^a,b   Ojala, Johanna ^a   Kaarniranta, Kai ^a,b   Hiltunen, Mikko ^a,b   Soininen, Hilkka ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Alzheimer; CHIP; FKBP51; Immunophilins; Neurofibrillary tangles; P62

Indexed keywords

4 PHENYLBUTYRIC ACID; ALVESPIMYCIN; CARBAMAZEPINE; CHAPERONE; CIS TRANS ISOMERASE; CYCLIN DEPENDENT KINASE 5; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 51; FK 506 BINDING PROTEIN 52; GLYCOGEN SYNTHASE KINASE 3BETA; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; LITHIUM; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 5; PROLINE; PROTEASOME; PROTEIN CHIP; RAPAMYCIN; SERINE; TANESPIMYCIN; TAU PROTEIN; THREONINE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; VALPROIC ACID;

ALZHEIMER DISEASE; AUTOPHAGY; BINDING AFFINITY; CATALYSIS; COMPLEX FORMATION; ENZYME ACTIVITY; HUMAN; LYSOSOME; MICROTUBULE; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STRUCTURE; REGULATORY MECHANISM; REVIEW; UBIQUITINATION; METABOLISM; PATHOLOGY; TAUOPATHY;

ALZHEIMER DISEASE; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MOLECULAR CHAPERONES; NEUROFIBRILLARY TANGLES; PROTEASOME ENDOPEPTIDASE COMPLEX; TAU PROTEINS; TAUOPATHIES;

EID: 78649767505     PISSN: 03010082     EISSN: 18735118     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2010.10.006     Document Type: Review

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