BRCA1 and BRCA2 heterozygosity in embryonic stem cells reduces radiation-induced Rad51 focus formation but is not associated with radiosensitivity

International Journal of Radiation Biology

Volumn 86, Issue 12, 2010, Pages 1095-1105

  Sioftanos, George ^a   Ismail, Amani ^a   Fhse, Lisa ^b   Shanley, Susan ^c   Worku, Mulugeta ^a   Short, Susan C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c ROYAL MARSDEN HOSPITAL   (United Kingdom)

Author keywords

BRCA1; BRCA2; Rad51; radiosensitivity; stem cells

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; RAD51 PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL NUCLEUS; EMBRYO; EMBRYONIC STEM CELL; FIBROBLAST; HETEROZYGOSITY; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIATION EXPOSURE; RADIOSENSITIVITY; SURVIVAL; WILD TYPE;

ANIMALS; CELL CYCLE; COLONY-FORMING UNITS ASSAY; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; EMBRYONIC STEM CELLS; GENES, BRCA1; GENES, BRCA2; HETEROZYGOTE; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; RAD51 RECOMBINASE; RADIATION TOLERANCE;

BACTERIA (MICROORGANISMS);

EID: 78649755411     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.3109/09553002.2010.501836     Document Type: Article

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