-
2
-
-
0025613812
-
Linkage of early-onset familial breast cancer to chromosome 17q21
-
Hall JM, Lee MK, Newman B, Morrow JE, Anderson LA, Huey B, King MC. Linkage of early-onset familial breast cancer to chromosome 17q21. Science 1990; 250: 1684-9.
-
(1990)
Science
, vol.250
, pp. 1684-1689
-
-
Hall, J.M.1
Lee, M.K.2
Newman, B.3
Morrow, J.E.4
Anderson, L.A.5
Huey, B.6
King, M.C.7
-
3
-
-
0026935108
-
Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome
-
Smith SA, Easton DF, Evans DG, Ponder BA. Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome. Nat Genet 1992; 2: 128-31.
-
(1992)
Nat. Genet.
, vol.2
, pp. 128-131
-
-
Smith, S.A.1
Easton, D.F.2
Evans, D.G.3
Ponder, B.A.4
-
4
-
-
0027960790
-
Loss of heterozygosity in familial tumors from three BRCA1-linked kindreds
-
Neuhausen SL, Marshall CJ. Loss of heterozygosity in familial tumors from three BRCA1-linked kindreds. Cancer Res 1994; 54: 6069-72.
-
(1994)
Cancer Res.
, vol.54
, pp. 6069-6072
-
-
Neuhausen, S.L.1
Marshall, C.J.2
-
5
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, Liu Q, Cochran C, Bennett LM, Ding W et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994; 266: 66-71.
-
(1994)
Science
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
Futreal, P.A.4
Harshman, K.5
Tavtigian, S.6
Liu, Q.7
Cochran, C.8
Bennett, L.M.9
Ding, W.10
-
6
-
-
0028006563
-
Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13
-
Wooster R, Neuhausen SL, Mangion J, Quirk Y, Ford D, Collins N, Nguyen K, Seal S, Tran T, Averill D et al. Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13. Science 1994; 265: 2088-90.
-
(1994)
Science
, vol.265
, pp. 2088-2090
-
-
Wooster, R.1
Neuhausen, S.L.2
Mangion, J.3
Quirk, Y.4
Ford, D.5
Collins, N.6
Nguyen, K.7
Seal, S.8
Tran, T.9
Averill, D.10
-
7
-
-
0006713602
-
Identification of the breast cancer susceptibility gene BRCA2
-
Wooster R, Bignell G, Lancaster J, Swift S, Seal S, Mangion J, Collins N, Gregory S, Gumbs C, Micklem G. Identification of the breast cancer susceptibility gene BRCA2. Nature 1995; 378: 789-92.
-
(1995)
Nature
, vol.378
, pp. 789-792
-
-
Wooster, R.1
Bignell, G.2
Lancaster, J.3
Swift, S.4
Seal, S.5
Mangion, J.6
Collins, N.7
Gregory, S.8
Gumbs, C.9
Micklem, G.10
-
8
-
-
0032441791
-
The genetics of breast cancer susceptibility
-
Rahman N, Stratton MR. The genetics of breast cancer susceptibility. Annu Rev Genet 1998; 32: 95-121.
-
(1998)
Annu. Rev. Genet.
, vol.32
, pp. 95-121
-
-
Rahman, N.1
Stratton, M.R.2
-
9
-
-
0028073794
-
BRCA1 mutations in primary breast and ovarian carcinomas
-
Futreal PA, Liu Q, Shattuck-Eidens D, Cochran C, Harshman K, Tavtigian S, Bennett LM, Haugen-Strano A, Swensen J, Miki Y et al. BRCA1 mutations in primary breast and ovarian carcinomas. Science 1994; 266: 120-2.
-
(1994)
Science
, vol.266
, pp. 120-122
-
-
Futreal, P.A.1
Liu, Q.2
Shattuck-Eidens, D.3
Cochran, C.4
Harshman, K.5
Tavtigian, S.6
Bennett, L.M.7
Haugen-Strano, A.8
Swensen, J.9
Miki, Y.10
-
10
-
-
9044225148
-
BRCA2 mutations in primary breast and ovarian cancers
-
Lancaster JM, Wooster R, Mangion J, Phelan CM, Cochran C, Gumbs C, Seal S, Barfoot R, Collins N, Bignell G, Patel S, Hamoudi R, Larsson C, Wiseman RW, Berchuck A, Iglehart JD, Marks JR, Ashworth A, Stratton MR, Futreal PA. BRCA2 mutations in primary breast and ovarian cancers. Nat Genet 1996; 13: 238-40.
-
(1996)
Nat. Genet.
, vol.13
, pp. 238-240
-
-
Lancaster, J.M.1
Wooster, R.2
Mangion, J.3
Phelan, C.M.4
Cochran, C.5
Gumbs, C.6
Seal, S.7
Barfoot, R.8
Collins, N.9
Bignell, G.10
Patel, S.11
Hamoudi, R.12
Larsson, C.13
Wiseman, R.W.14
Berchuck, A.15
Iglehart, J.D.16
Marks, J.R.17
Ashworth, A.18
Stratton, M.R.19
Futreal, P.A.20
more..
-
11
-
-
0030850047
-
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
-
Scully R, Chen J, Ochs RL, Keegan K, Hoekstra M, Feunteun J, Livingston DM. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell 1997; 90 425-35.
-
(1997)
Cell
, vol.90
, pp. 425-435
-
-
Scully, R.1
Chen, J.2
Ochs, R.L.3
Keegan, K.4
Hoekstra, M.5
Feunteun, J.6
Livingston, D.M.7
-
12
-
-
0030839860
-
Induction of phosphorylation on BRCA1 during the cell cycle and after DNA damage
-
Thomas JE, Smith M, Tonkinson JL, Rubinfeld B, Polakis P. Induction of phosphorylation on BRCA1 during the cell cycle and after DNA damage. Cell Growth Differ 1997; 8: 801-9.
-
(1997)
Cell Growth Differ.
, vol.8
, pp. 801-809
-
-
Thomas, J.E.1
Smith, M.2
Tonkinson, J.L.3
Rubinfeld, B.4
Polakis, P.5
-
13
-
-
0033527717
-
Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks
-
Cortez D, Wang Y, Qin J, Elledge SJ. Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks. Science 1999; 286: 1162-6.
-
(1999)
Science
, vol.286
, pp. 1162-1166
-
-
Cortez, D.1
Wang, Y.2
Qin, J.3
Elledge, S.J.4
-
14
-
-
0034125103
-
Role for ATM in DNA damage-induced phosphorylation of BRCA1
-
Gatei M, Scott SP, Filippovitch I, Soronika N, Lavin MF, Weber B, Khanna KK. Role for ATM in DNA damage-induced phosphorylation of BRCA1. Cancer Res 2000; 60: 3299-304.
-
(2000)
Cancer Res.
, vol.60
, pp. 3299-3304
-
-
Gatei, M.1
Scott, S.P.2
Filippovitch, I.3
Soronika, N.4
Lavin, M.F.5
Weber, B.6
Khanna, K.K.7
-
15
-
-
0035907395
-
Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies
-
Gatei M, Zhou BB, Hobson K, Scott S, Young D, Khanna KK. Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies. J Biol Chem 2001; 276: 17276-80.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 17276-17280
-
-
Gatei, M.1
Zhou, B.B.2
Hobson, K.3
Scott, S.4
Young, D.5
Khanna, K.K.6
-
16
-
-
0033566082
-
Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway
-
Chaturvedi P, Eng WK, Zhu Y, Mattern MR, Mishra R, Hurle MR, Zhang X, Annan RS, Lu Q, Faucette LF, Scott GF, Li X, Carr SA, Johnson RK, Winkler JD, Zhou BB. Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway. Oncogene 1999; 18 4047-54.
-
(1999)
Oncogene
, vol.18
, pp. 4047-4054
-
-
Chaturvedi, P.1
Eng, W.K.2
Zhu, Y.3
Mattern, M.R.4
Mishra, R.5
Hurle, M.R.6
Zhang, X.7
Annan, R.S.8
Lu, Q.9
Faucette, L.F.10
Scott, G.F.11
Li, X.12
Carr, S.A.13
Johnson, R.K.14
Winkler, J.D.15
Zhou, B.B.16
-
17
-
-
0033601346
-
Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome
-
Bell DW, Varley JM, Szydlo TE, Kang DH, Wahrer DC, Shannon KE, Lubratovich M, Verselis SJ, Isselbacher KJ, Fraumeni JF, Birch JM, Li FP, Garber JE, Haber DA. Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome. Science 1999; 286: 2528-31.
-
(1999)
Science
, vol.286
, pp. 2528-2831
-
-
Bell, D.W.1
Varley, J.M.2
Szydlo, T.E.3
Kang, D.H.4
Wahrer, D.C.5
Shannon, K.E.6
Lubratovich, M.7
Verselis, S.J.8
Isselbacher, K.J.9
Fraumeni, J.F.10
Birch, J.M.11
Li, F.P.12
Garber, J.E.13
Haber, D.A.14
-
18
-
-
0031472370
-
Association of BRCA1 with Rad51 in mitotic and meiotic cells
-
Scully R, Chen J, Plug A, Xiao Y, Weaver D, Feunteun J, Ashley T, Livingston DM. Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell 1997; 88: 265-75.
-
(1997)
Cell
, vol.88
, pp. 265-275
-
-
Scully, R.1
Chen, J.2
Plug, A.3
Xiao, Y.4
Weaver, D.5
Feunteun, J.6
Ashley, T.7
Livingston, D.M.8
-
19
-
-
0032159062
-
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells
-
Chen J, Silver DP, Walpita D, Cantor SB, Gazdar AF, Tomlinson G, Couch FJ, Weber BL, Ashley T, Livingston DM, Scully R. Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells. Mol Cell 1998; 2: 317-28.
-
(1998)
Mol. Cell
, vol.2
, pp. 317-328
-
-
Chen, J.1
Silver, D.P.2
Walpita, D.3
Cantor, S.B.4
Gazdar, A.F.5
Tomlinson, G.6
Couch, F.J.7
Weber, B.L.8
Ashley, T.9
Livingston, D.M.10
Scully, R.11
-
20
-
-
0026751113
-
Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein
-
Shinohara A, Ogawa H, Ogawa T. Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein. Cell 1992; 69: 457-70.
-
(1992)
Cell
, vol.69
, pp. 457-470
-
-
Shinohara, A.1
Ogawa, H.2
Ogawa, T.3
-
21
-
-
0027978039
-
Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein
-
Sung P. Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein. Science 1994; 265: 1241-3.
-
(1994)
Science
, vol.265
, pp. 1241-1243
-
-
Sung, P.1
-
22
-
-
0030584084
-
Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro
-
Baumann P, Benson FE, West SC. Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro. Cell 1996; 87: 757-66.
-
(1996)
Cell
, vol.87
, pp. 757-766
-
-
Baumann, P.1
Benson, F.E.2
West, S.C.3
-
23
-
-
0033400828
-
Genetic analysis of BRCA1 function in a defined tumor cell line
-
Scully R, Ganesan S, Vlasakova K, Chen J, Socolovsky M, Livingston DM. Genetic analysis of BRCA1 function in a defined tumor cell line. Mol Cell 1999; 4: 1093-9.
-
(1999)
Mol. Cell
, vol.4
, pp. 1093-1099
-
-
Scully, R.1
Ganesan, S.2
Vlasakova, K.3
Chen, J.4
Socolovsky, M.5
Livingston, D.M.6
-
24
-
-
0035874894
-
Homology-directed DNA repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation
-
Moynahan ME, Cui TY, Jasin M. Homology-directed DNA repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation. Cancer Res 2001; 61: 4842-50.
-
(2001)
Cancer Res.
, vol.61
, pp. 4842-4850
-
-
Moynahan, M.E.1
Cui, T.Y.2
Jasin, M.3
-
25
-
-
0034753160
-
Functions of BRCA1 and BRCA2 in the biological response to DNA damage
-
Venkitaraman AR. Functions of BRCA1 and BRCA2 in the biological response to DNA damage. J Cell Sci 2001; 114: 3591-8.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 3591-3598
-
-
Venkitaraman, A.R.1
-
26
-
-
0033618621
-
Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response
-
Zhong Q, Chen CF, Li S, Chen Y, Wang CC, Xiao J, Chen PL, Sharp ZD, Lee WH. Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response. Science 1999; 285: 747-50.
-
(1999)
Science
, vol.285
, pp. 747-750
-
-
Zhong, Q.1
Chen, C.F.2
Li, S.3
Chen, Y.4
Wang, C.C.5
Xiao, J.6
Chen, P.L.7
Sharp, Z.D.8
Lee, W.H.9
-
27
-
-
0034655991
-
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
-
Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev 2000; 14: 927-39.
-
(2000)
Genes Dev.
, vol.14
, pp. 927-939
-
-
Wang, Y.1
Cortez, D.2
Yazdi, P.3
Neff, N.4
Elledge, S.J.5
Qin, J.6
-
28
-
-
0034616915
-
Independence of R/M/N focus formation and the presence of intact BRCA1
-
Wu X, Petrini JH, Heine WF, Weaver DT, Livingston DM, Chen J. Independence of R/M/N focus formation and the presence of intact BRCA1. Science 2000; 289: 11.
-
(2000)
Science
, vol.289
, pp. 11
-
-
Wu, X.1
Petrini, J.H.2
Heine, W.F.3
Weaver, D.T.4
Livingston, D.M.5
Chen, J.6
-
29
-
-
0032567041
-
The many interfaces of Mre11
-
Haber JE. The many interfaces of Mre11. Cell 1998; 95: 583-6.
-
(1998)
Cell
, vol.95
, pp. 583-586
-
-
Haber, J.E.1
-
30
-
-
0035932978
-
Direct DNA binding by Brca1
-
Paull TT, Cortez D, Bowers B, Elledge SJ, Gellert M. Direct DNA binding by Brca1. Proc Natl Acad Sci USA 2001; 98: 6086-91.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 6086-6091
-
-
Paull, T.T.1
Cortez, D.2
Bowers, B.3
Elledge, S.J.4
Gellert, M.5
-
32
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998; 273: 5858-68.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
33
-
-
0032861343
-
Megabase chromatin domains involved in DNA double-strand breaks in vivo
-
Rogakou EP, Boon C, Redon C, Bonner WM. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 1999; 146: 905-16.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 905-916
-
-
Rogakou, E.P.1
Boon, C.2
Redon, C.3
Bonner, W.M.4
-
34
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol 2000; 10: 886-95.
-
(2000)
Curr. Biol.
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
35
-
-
0037012845
-
Genomic instability in mice lacking histone H2AX
-
Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA, Reina-San-Martin B, Coppola V, Meffre E, Difilippantonio MJ, Redon C, Pilch DR, Olaru A, Eckhaus M, Camerini-Otero RD, Tessarollo L, Livak F, Manova K, Bonner WM, Nussenzweig MC, Nussenzweig A. Genomic instability in mice lacking histone H2AX. Science 2002; 296: 922-7.
-
(2002)
Science
, vol.296
, pp. 922-927
-
-
Celeste, A.1
Petersen, S.2
Romanienko, P.J.3
Fernandez-Capetillo, O.4
Chen, H.T.5
Sedelnikova, O.A.6
Reina-San-Martin, B.7
Coppola, V.8
Meffre, E.9
Difilippantonio, M.J.10
Redon, C.11
Pilch, D.R.12
Olaru, A.13
Eckhaus, M.14
Camerini-Otero, R.D.15
Tessarollo, L.16
Livak, F.17
Manova, K.18
Bonner, W.M.19
Nussenzweig, M.C.20
Nussenzweig, A.21
more..
-
36
-
-
0035842893
-
BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations
-
Ye Q, Hu YF, Zhong H, Nye AC, Belmont AS, Li R. BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations. J Cell Biol 2001; 155: 911-21.
-
(2001)
J. Cell Biol.
, vol.155
, pp. 911-921
-
-
Ye, Q.1
Hu, Y.F.2
Zhong, H.3
Nye, A.C.4
Belmont, A.S.5
Li, R.6
-
37
-
-
0036258350
-
Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation
-
Foray N, Marot D, Randrianarison V, Venezia ND, Picard D, Perricaudet M, Favaudon V, Jeggo P. Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation. Mol Cell Biol 2002; 22: 4020-32.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 4020-4032
-
-
Foray, N.1
Marot, D.2
Randrianarison, V.3
Venezia, N.D.4
Picard, D.5
Perricaudet, M.6
Favaudon, V.7
Jeggo, P.8
-
38
-
-
0033600235
-
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
-
Yuan ZM, Shioya H, Ishiko T, Sun X, Gu J, Huang YY, Lu H, Kharbanda S, Weichselbaum R, Kufe D. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature 1999; 399 814-7.
-
(1999)
Nature
, vol.399
, pp. 814-817
-
-
Yuan, Z.M.1
Shioya, H.2
Ishiko, T.3
Sun, X.4
Gu, J.5
Huang, Y.Y.6
Lu, H.7
Kharbanda, S.8
Weichselbaum, R.9
Kufe, D.10
-
39
-
-
0036241988
-
c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage
-
Yoshida K, Komatsu K, Wang HG, Kufe D. c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage. Mol Cell Biol 2002; 22: 3292-300.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 3292-3300
-
-
Yoshida, K.1
Komatsu, K.2
Wang, H.G.3
Kufe, D.4
-
40
-
-
0034213735
-
Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivation
-
Yu VP, Koehler M, Steinlein C, Schmid M, Hanakahi LA, van Gool AJ, West SC, Venkitaraman AR. Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivation. Genes Dev 2000; 14: 1400-6.
-
(2000)
Genes Dev.
, vol.14
, pp. 1400-1406
-
-
Yu, V.P.1
Koehler, M.2
Steinlein, C.3
Schmid, M.4
Hanakahi, L.A.5
van Gool, A.J.6
West, S.C.7
Venkitaraman, A.R.8
-
41
-
-
0035099044
-
BRCA2 is required for homology-directed repair of chromosomal breaks
-
Moynahan ME, Pierce AJ, Jasin M. BRCA2 is required for homology-directed repair of chromosomal breaks. Mol Cell 2001; 7 263-72.
-
(2001)
Mol. Cell
, vol.7
, pp. 263-272
-
-
Moynahan, M.E.1
Pierce, A.J.2
Jasin, M.3
-
42
-
-
0035105999
-
Role of BRCA2 in control of the RAD51 recombination and DNA repair protein
-
Davies AA, Masson JY, McIlwraith MJ, Stasiak AZ, Stasiak A, Venkitaraman AR, West SC. Role of BRCA2 in control of the RAD51 recombination and DNA repair protein. Mol Cell 2001; 7: 273-82.
-
(2001)
Mol. Cell
, vol.7
, pp. 273-282
-
-
Davies, A.A.1
Masson, J.Y.2
McIlwraith, M.J.3
Stasiak, A.Z.4
Stasiak, A.5
Venkitaraman, A.R.6
West, S.C.7
-
43
-
-
0029830051
-
Transcriptional activation by BRCA1
-
Chapman MS, Verma IM. Transcriptional activation by BRCA1. Nature 1996; 382: 678-9.
-
(1996)
Nature
, vol.382
, pp. 678-679
-
-
Chapman, M.S.1
Verma, I.M.2
-
44
-
-
0030474170
-
Evidence for a transcriptional activation function of BRCA1 C-terminal region
-
Monteiro AN, August A, Hanafusa H. Evidence for a transcriptional activation function of BRCA1 C-terminal region. Proc Natl Acad Sci USA 1996; 93: 13595-9.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13595-13599
-
-
Monteiro, A.N.1
August, A.2
Hanafusa, H.3
-
45
-
-
0030965157
-
BRCA1 is a component of the RNA polymerase II holoenzyme
-
Scully R, Anderson SF, Chao DM, Wei W, Ye L, Young RA, Livingston DM, Parvin JD. BRCA1 is a component of the RNA polymerase II holoenzyme. Proc Natl Acad Sci USA 1997; 94: 5605-10.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5605-5610
-
-
Scully, R.1
Anderson, S.F.2
Chao, D.M.3
Wei, W.4
Ye, L.5
Young, R.A.6
Livingston, D.M.7
Parvin, J.D.8
-
46
-
-
0031830844
-
BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A
-
Anderson SF, Schlegel BP, Nakajima T, Wolpin ES, Parvin JD. BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A. Nat Genet 1998; 19: 254-6.
-
(1998)
Nat. Genet.
, vol.19
, pp. 254-256
-
-
Anderson, S.F.1
Schlegel, B.P.2
Nakajima, T.3
Wolpin, E.S.4
Parvin, J.D.5
-
47
-
-
0036682183
-
The BRCA1 and BARD1 association with the RNA polymerase II holoenzyme
-
Chiba N, Parvin JD. The BRCA1 and BARD1 association with the RNA polymerase II holoenzyme. Cancer Res 2002; 62: 4222-8.
-
(2002)
Cancer Res.
, vol.62
, pp. 4222-4228
-
-
Chiba, N.1
Parvin, J.D.2
-
48
-
-
0036261733
-
BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets
-
MacLachlan TK, Takimoto R, El-Deiry WS. BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets. Mol Cell Biol 2002; 22: 4280-92.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 4280-4292
-
-
MacLachlan, T.K.1
Takimoto, R.2
El-Deiry, W.S.3
-
49
-
-
0032473879
-
BRCA1 physically associates with p53 and stimulates its transcriptional activity
-
Zhang H, Somasundaram K, Peng Y, Tian H, Bi D, Weber BL, El-Deiry WS. BRCA1 physically associates with p53 and stimulates its transcriptional activity. Oncogene 1998; 16: 1713-21.
-
(1998)
Oncogene
, vol.16
, pp. 1713-1721
-
-
Zhang, H.1
Somasundaram, K.2
Peng, Y.3
Tian, H.4
Bi, D.5
Weber, B.L.6
El-Deiry, W.S.7
-
50
-
-
0033637860
-
Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1
-
Zheng L, Pan H, Li S, Flesken-Nikitin A, Chen PL, Boyer TG, Lee WH. Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1. Mol Cell 2000; 6: 757-68.
-
(2000)
Mol. Cell
, vol.6
, pp. 757-768
-
-
Zheng, L.1
Pan, H.2
Li, S.3
Flesken-Nikitin, A.4
Chen, P.L.5
Boyer, T.G.6
Lee, W.H.7
-
51
-
-
0034644220
-
Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response
-
Li S, Ting NS, Zheng L, Chen PL, Ziv Y, Shiloh Y, Lee EY, Lee WH. Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response. Nature 2000; 406: 210-5.
-
(2000)
Nature
, vol.406
, pp. 210-215
-
-
Li, S.1
Ting, N.S.2
Zheng, L.3
Chen, P.L.4
Ziv, Y.5
Shiloh, Y.6
Lee, E.Y.7
Lee, W.H.8
-
52
-
-
0034624967
-
Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes
-
Ouchi T, Lee SW, Ouchi M, Aaronson SA, Horvath CM. Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes. Proc Natl Acad Sci USA 2000; 97: 5208-13.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5208-5213
-
-
Ouchi, T.1
Lee, S.W.2
Ouchi, M.3
Aaronson, S.A.4
Horvath, C.M.5
-
53
-
-
10744233204
-
EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer
-
Hughes-Davies L, Huntsman D, Ruas M, Fuks F, Bye J, Chin SF, Milner J, Brown LA, Hsu F, Gilks B, Nielsen T, Schulzer M, Chia S, Ragaz J, Cahn A, Linger L, Ozdag H, Cattaneo E, Jordanova ES, Schuuring E, Yu DS, Venkitaraman A, Ponder B, Doherty A, Aparicio S, Bentley D, Theillet C, Ponting CP, Caldas C, Kouzarides T. EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell 2003; 115: 523-35.
-
(2003)
Cell
, vol.115
, pp. 523-535
-
-
Hughes-Davies, L.1
Huntsman, D.2
Ruas, M.3
Fuks, F.4
Bye, J.5
Chin, S.F.6
Milner, J.7
Brown, L.A.8
Hsu, F.9
Gilks, B.10
Nielsen, T.11
Schulzer, M.12
Chia, S.13
Ragaz, J.14
Cahn, A.15
Linger, L.16
Ozdag, H.17
Cattaneo, E.18
Jordanova, E.S.19
Schuuring, E.20
Yu, D.S.21
Venkitaraman, A.22
Ponder, B.23
Doherty, A.24
Aparicio, S.25
Bentley, D.26
Theillet, C.27
Ponting, C.P.28
Caldas, C.29
Kouzarides, T.30
more..
-
54
-
-
0036510163
-
BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage
-
Yarden RI, Pardo-Reoyo S, Sgagias M, Cowan KH, Brody LC. BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage. Nat Genet 2002; 30: 285-9.
-
(2002)
Nat. Genet.
, vol.30
, pp. 285-289
-
-
Yarden, R.I.1
Pardo-Reoyo, S.2
Sgagias, M.3
Cowan, K.H.4
Brody, L.C.5
-
55
-
-
0035854674
-
BRCA1 is a selective co-activator of 14-3-3 sigma gene transcription in mouse embryonic stem cells
-
Aprelikova O, Pace AJ, Fang B, Koller BH, Liu ET. BRCA1 is a selective co-activator of 14-3-3 sigma gene transcription in mouse embryonic stem cells. J Biol Chem 2001; 276: 25647-50.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25647-25650
-
-
Aprelikova, O.1
Pace, A.J.2
Fang, B.3
Koller, B.H.4
Liu, E.T.5
-
56
-
-
0033612303
-
Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1
-
Harkin DP, Bean JM, Miklos D, Song YH, Truong VB, Englert C, Christians FC, Ellisen LW, Maheswaran S, Oliner JD, Haber DA. Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1. Cell 1999; 97: 575-86.
-
(1999)
Cell
, vol.97
, pp. 575-586
-
-
Harkin, D.P.1
Bean, J.M.2
Miklos, D.3
Song, Y.H.4
Truong, V.B.5
Englert, C.6
Christians, F.C.7
Ellisen, L.W.8
Maheswaran, S.9
Oliner, J.D.10
Haber, D.A.11
-
57
-
-
0034723347
-
BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression
-
MacLachlan TK, Somasundaram K, Sgagias M, Shifman Y, Muschel RJ, Cowan KH, El-Deiry WS. BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression. J Biol Chem 2000; 275: 2777-85.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2777-2785
-
-
MacLachlan, T.K.1
Somasundaram, K.2
Sgagias, M.3
Shifman, Y.4
Muschel, R.J.5
Cowan, K.H.6
El-Deiry, W.S.7
-
58
-
-
0030759895
-
Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1
-
Somasundaram, K, Zhang H, Zeng YX, Houvras Y, Peng Y, Wu GS, Licht JD, Weber BL, El-Deiry WS. Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1. Nature 1997; 389: 187-90.
-
(1997)
Nature
, vol.389
, pp. 187-190
-
-
Somasundaram, K.1
Zhang, H.2
Zeng, Y.X.3
Houvras, Y.4
Peng, Y.5
Wu, G.S.6
Licht, J.D.7
Weber, B.L.8
El-Deiry, W.S.9
-
59
-
-
0037046491
-
BRCA1, transactivates the cyclin-dependent kinase inhibitor p27(Kip1)
-
Williamson EA, Dadmanesh F, Koeffler HP. BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1). Oncogene 2002; 21: 3199-206.
-
(2002)
Oncogene
, vol.21
, pp. 3199-3206
-
-
Williamson, E.A.1
Dadmanesh, F.2
Koeffler, H.P.3
-
60
-
-
0035951405
-
A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression
-
Marmorstein LY, Kinev AV, Chan GK, Bochar DA, Beniya H, Epstein JA, Yen TJ, Shiekhattar R. A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression. Cell 2001; 104: 247-57.
-
(2001)
Cell
, vol.104
, pp. 247-257
-
-
Marmorstein, L.Y.1
Kinev, A.V.2
Chan, G.K.3
Bochar, D.A.4
Beniya, H.5
Epstein, J.A.6
Yen, T.J.7
Shiekhattar, R.8
-
61
-
-
0033166981
-
Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2
-
Lee H, Trainer AH, Friedman LS, Thistlethwaite FC, Evans MJ, Ponder BA, Venkitaraman AR. Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2. Mol Cell 1999; 4: 1-10.
-
(1999)
Mol. Cell
, vol.4
, pp. 1-10
-
-
Lee, H.1
Trainer, A.H.2
Friedman, L.S.3
Thistlethwaite, F.C.4
Evans, M.J.5
Ponder, B.A.6
Venkitaraman, A.R.7
-
62
-
-
0035872462
-
TP53 mutations in breast cancer associated with BRCA1 or BRCA2 germ-line mutations: Distinctive spectrum and structural distribution
-
Greenblatt MS, Chappuis PO, Bond JP, Hamel N, Foulkes WD. TP53 mutations in breast cancer associated with BRCA1 or BRCA2 germ-line mutations: distinctive spectrum and structural distribution. Cancer Res 2001; 61: 4092-7.
-
(2001)
Cancer Res.
, vol.61
, pp. 4092-4097
-
-
Greenblatt, M.S.1
Chappuis, P.O.2
Bond, J.P.3
Hamel, N.4
Foulkes, W.D.5
|