메뉴 건너뛰기




Volumn 9, Issue 12, 2010, Pages 1256-1263

Coping with DNA double strand breaks

Author keywords

DNA double strand breaks; DNA repair; Homologous recombination; Non homologous end joining

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; DOUBLE STRANDED DNA; HISTONE H2A; NUCLEOPROTEIN; RAD51 PROTEIN; RAD52 PROTEIN; UBIQUITIN PROTEIN LIGASE E3;

EID: 78649449207     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2010.09.018     Document Type: Review
Times cited : (88)

References (64)
  • 1
    • 0001292985 scopus 로고
    • Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells
    • Taub R., Kirsch I., Morton C., Lenoir G., Swan D., Tronick S., Aaronson S., Leder P. Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells. Proc. Natl. Acad. Sci. U.S.A. 1982, 79:7837-7841.
    • (1982) Proc. Natl. Acad. Sci. U.S.A. , vol.79 , pp. 7837-7841
    • Taub, R.1    Kirsch, I.2    Morton, C.3    Lenoir, G.4    Swan, D.5    Tronick, S.6    Aaronson, S.7    Leder, P.8
  • 2
    • 0018882091 scopus 로고
    • Type II DNA topoisomerases: enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break
    • Liu L.F., Liu C.C., Alberts B.M. Type II DNA topoisomerases: enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break. Cell 1980, 19:697-707.
    • (1980) Cell , vol.19 , pp. 697-707
    • Liu, L.F.1    Liu, C.C.2    Alberts, B.M.3
  • 3
    • 0018776894 scopus 로고
    • Hydroperoxide metabolism in mammalian organs
    • Chance B., Sies H., Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 1979, 59:527-605.
    • (1979) Physiol. Rev. , vol.59 , pp. 527-605
    • Chance, B.1    Sies, H.2    Boveris, A.3
  • 5
    • 67649852281 scopus 로고    scopus 로고
    • DNA repair: common approaches to fixing double-strand breaks
    • Hiom K. DNA repair: common approaches to fixing double-strand breaks. Curr. Biol. 2009, 19:R523-R525.
    • (2009) Curr. Biol. , vol.19
    • Hiom, K.1
  • 6
    • 33645781346 scopus 로고    scopus 로고
    • Making ends meet: repairing breaks in bacterial DNA by non-homologous end-joining
    • Bowater R., Doherty A.J. Making ends meet: repairing breaks in bacterial DNA by non-homologous end-joining. PLoS Genet. 2006, 2:e8.
    • (2006) PLoS Genet. , vol.2
    • Bowater, R.1    Doherty, A.J.2
  • 7
    • 0020373190 scopus 로고
    • Somatic cells efficiently join unrelated DNA segments end-to-end
    • Wilson J.H., Berget P.B., Pipas J.M. Somatic cells efficiently join unrelated DNA segments end-to-end. Mol. Cell. Biol. 1982, 2:1258-1269.
    • (1982) Mol. Cell. Biol. , vol.2 , pp. 1258-1269
    • Wilson, J.H.1    Berget, P.B.2    Pipas, J.M.3
  • 8
    • 0022827675 scopus 로고
    • Mechanism of interaction between Ku protein and DNA
    • Mimori T., Hardin J.A. Mechanism of interaction between Ku protein and DNA. J. Biol. Chem. 1986, 261:10375-10379.
    • (1986) J. Biol. Chem. , vol.261 , pp. 10375-10379
    • Mimori, T.1    Hardin, J.A.2
  • 9
    • 0027397867 scopus 로고
    • The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen
    • Gottlieb T.M., Jackson S.P. The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 1993, 72:131-142.
    • (1993) Cell , vol.72 , pp. 131-142
    • Gottlieb, T.M.1    Jackson, S.P.2
  • 10
    • 0024356877 scopus 로고
    • HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex
    • de Vries E., van Driel W., Bergsma W.G., Arnberg A.C., van der Vliet P.C. HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex. J. Mol. Biol. 1989, 208:65-78.
    • (1989) J. Mol. Biol. , vol.208 , pp. 65-78
    • de Vries, E.1    van Driel, W.2    Bergsma, W.G.3    Arnberg, A.C.4    van der Vliet, P.C.5
  • 11
    • 0032518680 scopus 로고    scopus 로고
    • Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks
    • Ramsden D.A., Gellert M. Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks. EMBO J. 1998, 17:609-614.
    • (1998) EMBO J. , vol.17 , pp. 609-614
    • Ramsden, D.A.1    Gellert, M.2
  • 12
    • 77953229115 scopus 로고    scopus 로고
    • The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
    • Lieber M.R. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu. Rev. Biochem. 2010, 79:181-211.
    • (2010) Annu. Rev. Biochem. , vol.79 , pp. 181-211
    • Lieber, M.R.1
  • 13
    • 0030746109 scopus 로고    scopus 로고
    • Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies
    • Yaneva M., Kowalewski T., Lieber M.R. Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies. EMBO J. 1997, 16:5098-5112.
    • (1997) EMBO J. , vol.16 , pp. 5098-5112
    • Yaneva, M.1    Kowalewski, T.2    Lieber, M.R.3
  • 14
    • 1942538492 scopus 로고    scopus 로고
    • ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
    • Stiff T., O'Driscoll M., Rief N., Iwabuchi K., Lobrich M., Jeggo P.A. ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res. 2004, 64:2390-2396.
    • (2004) Cancer Res. , vol.64 , pp. 2390-2396
    • Stiff, T.1    O'Driscoll, M.2    Rief, N.3    Iwabuchi, K.4    Lobrich, M.5    Jeggo, P.A.6
  • 15
    • 0032931844 scopus 로고    scopus 로고
    • The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance
    • Moreau S., Ferguson J.R., Symington L.S. The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance. Mol. Cell. Biol. 1999, 19:556-566.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 556-566
    • Moreau, S.1    Ferguson, J.R.2    Symington, L.S.3
  • 17
    • 0037155703 scopus 로고    scopus 로고
    • Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
    • Ma Y., Pannicke U., Schwarz K., Lieber M.R. Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell 2002, 108:781-794.
    • (2002) Cell , vol.108 , pp. 781-794
    • Ma, Y.1    Pannicke, U.2    Schwarz, K.3    Lieber, M.R.4
  • 18
    • 77952583540 scopus 로고    scopus 로고
    • Purification and characterization of exonuclease-free Artemis: implications for DNA-PK-dependent processing of DNA termini in NHEJ-catalyzed DSB repair
    • Pawelczak K.S., Turchi J.J. Purification and characterization of exonuclease-free Artemis: implications for DNA-PK-dependent processing of DNA termini in NHEJ-catalyzed DSB repair. DNA Repair (Amst) 2010, 9:670-677.
    • (2010) DNA Repair (Amst) , vol.9 , pp. 670-677
    • Pawelczak, K.S.1    Turchi, J.J.2
  • 20
    • 34848841930 scopus 로고    scopus 로고
    • Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence
    • Gu J., Lu H., Tsai A.G., Schwarz K., Lieber M.R. Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence. Nucleic Acids Res. 2007, 35:5755-5762.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 5755-5762
    • Gu, J.1    Lu, H.2    Tsai, A.G.3    Schwarz, K.4    Lieber, M.R.5
  • 21
    • 33847193121 scopus 로고    scopus 로고
    • XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
    • Gu J., Lu H., Tippin B., Shimazaki N., Goodman M.F., Lieber M.R. XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps. EMBO J. 2007, 26:1010-1023.
    • (2007) EMBO J. , vol.26 , pp. 1010-1023
    • Gu, J.1    Lu, H.2    Tippin, B.3    Shimazaki, N.4    Goodman, M.F.5    Lieber, M.R.6
  • 22
    • 54849404458 scopus 로고    scopus 로고
    • MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings
    • McVey M., Lee S.E. MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings. Trends Genet. 2008, 24:529-538.
    • (2008) Trends Genet. , vol.24 , pp. 529-538
    • McVey, M.1    Lee, S.E.2
  • 23
    • 67349246802 scopus 로고    scopus 로고
    • CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle
    • Yun M.H., Hiom K. CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle. Nature 2009, 459:460-463.
    • (2009) Nature , vol.459 , pp. 460-463
    • Yun, M.H.1    Hiom, K.2
  • 24
    • 53549093050 scopus 로고    scopus 로고
    • The P. furiosus mre11/rad50 complex promotes 5' strand resection at a DNA double-strand break
    • Hopkins B.B., Paull T.T. The P. furiosus mre11/rad50 complex promotes 5' strand resection at a DNA double-strand break. Cell 2008, 135:250-260.
    • (2008) Cell , vol.135 , pp. 250-260
    • Hopkins, B.B.1    Paull, T.T.2
  • 25
    • 66149114020 scopus 로고    scopus 로고
    • Human CtIP mediates cell cycle control of DNA end resection and double strand break repair
    • Huertas P., Jackson S.P. Human CtIP mediates cell cycle control of DNA end resection and double strand break repair. J. Biol. Chem. 2009, 284:9558-9565.
    • (2009) J. Biol. Chem. , vol.284 , pp. 9558-9565
    • Huertas, P.1    Jackson, S.P.2
  • 27
    • 34948872046 scopus 로고    scopus 로고
    • Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination
    • Limbo O., Chahwan C., Yamada Y., de Bruin R.A., Wittenberg C., Russell P. Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Mol. Cell 2007, 28:134-146.
    • (2007) Mol. Cell , vol.28 , pp. 134-146
    • Limbo, O.1    Chahwan, C.2    Yamada, Y.3    de Bruin, R.A.4    Wittenberg, C.5    Russell, P.6
  • 28
    • 34548401682 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Sae2- and Tel1-dependent single-strand DNA formation at DNA break promotes microhomology-mediated end joining
    • Lee K., Lee S.E. Saccharomyces cerevisiae Sae2- and Tel1-dependent single-strand DNA formation at DNA break promotes microhomology-mediated end joining. Genetics 2007, 176:2003-2014.
    • (2007) Genetics , vol.176 , pp. 2003-2014
    • Lee, K.1    Lee, S.E.2
  • 29
    • 3242879258 scopus 로고    scopus 로고
    • The taming of a transposon: V(D)J recombination and the immune system
    • Jones J.M., Gellert M. The taming of a transposon: V(D)J recombination and the immune system. Immunol. Rev. 2004, 200:233-248.
    • (2004) Immunol. Rev. , vol.200 , pp. 233-248
    • Jones, J.M.1    Gellert, M.2
  • 30
    • 0029967722 scopus 로고    scopus 로고
    • Similarities between initiation of V(D)J recombination and retroviral integration
    • van Gent D.C., Mizuuchi K., Gellert M. Similarities between initiation of V(D)J recombination and retroviral integration. Science 1996, 271:1592-1594.
    • (1996) Science , vol.271 , pp. 1592-1594
    • van Gent, D.C.1    Mizuuchi, K.2    Gellert, M.3
  • 31
    • 0030837472 scopus 로고    scopus 로고
    • V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation
    • Bogue M.A., Wang C., Zhu C., Roth D.B. V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation. Immunity 1997, 7:37-47.
    • (1997) Immunity , vol.7 , pp. 37-47
    • Bogue, M.A.1    Wang, C.2    Zhu, C.3    Roth, D.B.4
  • 32
    • 0029655319 scopus 로고    scopus 로고
    • Mechanistic constraints on diversity in human V(D)J recombination
    • Gauss G.H, Lieber M.R. Mechanistic constraints on diversity in human V(D)J recombination. Mol. Cell. Biol. 1996, 16:258-269.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 258-269
    • Gauss, G.H.1    Lieber, M.R.2
  • 33
    • 41149132841 scopus 로고    scopus 로고
    • Fixing DNA breaks during class switch recombination
    • Jolly C.J., Cook A.J., Manis J.P. Fixing DNA breaks during class switch recombination. J. Exp. Med. 2008, 205:509-513.
    • (2008) J. Exp. Med. , vol.205 , pp. 509-513
    • Jolly, C.J.1    Cook, A.J.2    Manis, J.P.3
  • 37
    • 0030273141 scopus 로고    scopus 로고
    • The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching
    • Rolink A., Melchers F., Andersson J. The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching. Immunity 1996, 5:319-330.
    • (1996) Immunity , vol.5 , pp. 319-330
    • Rolink, A.1    Melchers, F.2    Andersson, J.3
  • 38
    • 33847276659 scopus 로고    scopus 로고
    • The catalytic subunit of DNA-protein kinase (DNA-PKcs) is not required for Ig class-switch recombination
    • Kiefer K., Oshinsky J., Kim J., Nakajima P.B., Bosma G.C., Bosma M.J. The catalytic subunit of DNA-protein kinase (DNA-PKcs) is not required for Ig class-switch recombination. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:2843-2848.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 2843-2848
    • Kiefer, K.1    Oshinsky, J.2    Kim, J.3    Nakajima, P.B.4    Bosma, G.C.5    Bosma, M.J.6
  • 40
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • Rogakou E.P., Pilch D.R., Orr A.H., Ivanova V.S., Bonner W.M. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 1998, 273:5858-5868.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 42
    • 53649104599 scopus 로고    scopus 로고
    • Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
    • Mimitou E.P., Symington L.S. Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 2008, 455:770-774.
    • (2008) Nature , vol.455 , pp. 770-774
    • Mimitou, E.P.1    Symington, L.S.2
  • 43
    • 0037199924 scopus 로고    scopus 로고
    • Rad52 protein associates with replication protein A (RPA)-single-stranded DNA to accelerate Rad51-mediated displacement of RPA and presynaptic complex formation
    • Sugiyama T., Kowalczykowski S.C. Rad52 protein associates with replication protein A (RPA)-single-stranded DNA to accelerate Rad51-mediated displacement of RPA and presynaptic complex formation. J. Biol. Chem. 2002, 277:31663-31672.
    • (2002) J. Biol. Chem. , vol.277 , pp. 31663-31672
    • Sugiyama, T.1    Kowalczykowski, S.C.2
  • 44
    • 0032574733 scopus 로고    scopus 로고
    • The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment
    • Chen P.L., Chen C.F., Chen Y., Xiao J., Sharp Z.D., Lee W.H. The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:5287-5292.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 5287-5292
    • Chen, P.L.1    Chen, C.F.2    Chen, Y.3    Xiao, J.4    Sharp, Z.D.5    Lee, W.H.6
  • 45
    • 78149425175 scopus 로고    scopus 로고
    • Regulation of homologous recombination in eukaryotes
    • Heyer W.D., Ehmsen K.T., Liu J. Regulation of homologous recombination in eukaryotes. Annu. Rev. Genet. 2010, 44:113-139.
    • (2010) Annu. Rev. Genet. , vol.44 , pp. 113-139
    • Heyer, W.D.1    Ehmsen, K.T.2    Liu, J.3
  • 49
    • 56749119855 scopus 로고    scopus 로고
    • Identification of Holliday junction resolvases from humans and yeast
    • Ip S.C., Rass U., Blanco M.G., Flynn H.R., Skehel J.M., West S.C. Identification of Holliday junction resolvases from humans and yeast. Nature 2008, 456:357-361.
    • (2008) Nature , vol.456 , pp. 357-361
    • Ip, S.C.1    Rass, U.2    Blanco, M.G.3    Flynn, H.R.4    Skehel, J.M.5    West, S.C.6
  • 50
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • Zou L., Elledge S.J. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 2003, 300:1542-1548.
    • (2003) Science , vol.300 , pp. 1542-1548
    • Zou, L.1    Elledge, S.J.2
  • 55
    • 77952683886 scopus 로고    scopus 로고
    • DNA repair: decision at the break point
    • Boulton S.J. DNA repair: decision at the break point. Nature 2010, 465:301-302.
    • (2010) Nature , vol.465 , pp. 301-302
    • Boulton, S.J.1
  • 56
    • 77957291620 scopus 로고    scopus 로고
    • The interplay between BRCA1 and 53BP1 influences death, aging, senescence and cancer
    • Lowndes N.F. The interplay between BRCA1 and 53BP1 influences death, aging, senescence and cancer. DNA Rep. (Amst) 2010, 9:1112-1116.
    • (2010) DNA Rep. (Amst) , vol.9 , pp. 1112-1116
    • Lowndes, N.F.1
  • 60
    • 0141705373 scopus 로고    scopus 로고
    • Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4
    • Morshead K.B., Ciccone D.N., Taverna S.D., Allis C.D., Oettinger M.A. Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:11577-11582.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 11577-11582
    • Morshead, K.B.1    Ciccone, D.N.2    Taverna, S.D.3    Allis, C.D.4    Oettinger, M.A.5
  • 62
    • 63049101044 scopus 로고    scopus 로고
    • Regulatory ubiquitylation in response to DNA double-strand breaks
    • Panier S., Durocher D. Regulatory ubiquitylation in response to DNA double-strand breaks. DNA Repair (Amst) 2009, 8:436-443.
    • (2009) DNA Repair (Amst) , vol.8 , pp. 436-443
    • Panier, S.1    Durocher, D.2
  • 63
    • 47349107760 scopus 로고    scopus 로고
    • ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
    • Goodarzi A.A., Noon A.T., Deckbar D., Ziv Y., Shiloh Y., Lobrich M., Jeggo P.A. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol. Cell 2008, 31:167-177.
    • (2008) Mol. Cell , vol.31 , pp. 167-177
    • Goodarzi, A.A.1    Noon, A.T.2    Deckbar, D.3    Ziv, Y.4    Shiloh, Y.5    Lobrich, M.6    Jeggo, P.A.7
  • 64
    • 75949122330 scopus 로고    scopus 로고
    • 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair
    • Noon A.T., Shibata A., Rief N., Lobrich M., Stewart G.S., Jeggo P.A., Goodarzi A.A. 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair. Nat. Cell Biol. 2010, 12:177-184.
    • (2010) Nat. Cell Biol. , vol.12 , pp. 177-184
    • Noon, A.T.1    Shibata, A.2    Rief, N.3    Lobrich, M.4    Stewart, G.S.5    Jeggo, P.A.6    Goodarzi, A.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.