DNA mismatch repair: The hands of a genome guardian

Structure

Volumn 8, Issue 12, 2000, Pages R237-R241

  Hopfner, Karl Peter ^a   Tainer, John A ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASE MISPAIRING; CONFORMATION; CRYSTAL STRUCTURE; DNA DAMAGE; DNA REPAIR; DNA STRUCTURE; GENOME; PRIORITY JOURNAL; PROTEIN DNA BINDING; SHORT SURVEY;

ADENOSINE TRIPHOSPHATASES; BACTERIAL PROTEINS; BASE PAIR MISMATCH; COMPUTER SIMULATION; DNA REPAIR; DNA, BACTERIAL; DNA-BINDING PROTEINS; ESCHERICHIA COLI PROTEINS; GENOME, BACTERIAL; MODELS, MOLECULAR; MUTS DNA MISMATCH-BINDING PROTEIN;

EID: 0034483133     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(00)00545-1     Document Type: Review

References (29)

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4. Mismatch repair and cancer susceptibility
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7. Multiple functions of MutS- and MutL-related heterocomplexes
8. A phylogenomic study of the MutS family of proteins
9. Conserved domains in DNA repair proteins and evolution of repair systems
10. Eukaryotic DNA mismatch repair
11. The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch
12. hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA
13. MutS mediates heteroduplex loop formation by a translocation mechanism
14. Nucleotide-promoted release of hMutSα from heteroduplex DNA is consistent with an ATP-dependent translocation mechanism
15. Modulation of MutS ATP hydrolysis by DNA cofactors
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17. ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair
18. ATP-dependent assembly of a ternary complex consisting of a DNA mismatch and the yeast MSH2-MSH6 and MLH1-PMS1 protein complexes
19. ATP hydrolysis-dependent formation of a dynamic ternary nucleoprotein complex with MutS and MutL
20. The MutL ATPase is required for mismatch repair
21. Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA
22. The crystal structure of DNA mismatch repair protein MutS binding to a G·T mismatch
23. Eukaryotic mismatch repair: An update
24. Biological implications from structures of DNA repair proteins
25. Recognition of a TG mismatch: The crystal structure of very short patch repair endonuclease in complex with a DNA duplex
26. Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily
27. Transformation of MutL by ATP binding and hydrolysis: A switch in DNA mismatch repair
28. Type II DNA topoisomerases