-
1
-
-
0026621245
-
ABC transporters: From microorganisms to man
-
Higgins C.F. ABC transporters: from microorganisms to man. Annu. Rev. Cell. Biol. 8:1992;67-113.
-
(1992)
Annu. Rev. Cell. Biol.
, vol.8
, pp. 67-113
-
-
Higgins, C.F.1
-
2
-
-
0032698874
-
ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans
-
Holland I.B., Blight M.A. ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans. J. Mol. Biol. 293:1999;381-399.
-
(1999)
J. Mol. Biol.
, vol.293
, pp. 381-399
-
-
Holland, I.B.1
Blight, M.A.2
-
3
-
-
0036909285
-
Structure and mechanism of ABC transporters
-
Schmitt L., Tampé R. Structure and mechanism of ABC transporters. Curr. Opin. Struct. Biol. 12:2002;754-760.
-
(2002)
Curr. Opin. Struct. Biol.
, vol.12
, pp. 754-760
-
-
Schmitt, L.1
Tampé, R.2
-
4
-
-
0033105094
-
Conserved domains in DNA repair proteins and evolution of repair systems
-
Aravind L., Walker D.R., Koonin E.V. Conserved domains in DNA repair proteins and evolution of repair systems. Nucleic Acids Res. 27:1999;1223-1242.
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 1223-1242
-
-
Aravind, L.1
Walker, D.R.2
Koonin, E.V.3
-
5
-
-
0032912589
-
Structure and function of the CFTR chloride channel
-
Sheppard D.N., Welsh M.J. Structure and function of the CFTR chloride channel. Physiol Rev. 79:1999;S23-S45.
-
(1999)
Physiol Rev.
, vol.79
-
-
Sheppard, D.N.1
Welsh, M.J.2
-
6
-
-
0027550821
-
The cystic fibrosis gene and its product CFTR
-
Harris A., Argent B.E. The cystic fibrosis gene and its product CFTR. Semin Cell Biol. 4:1993;37-44.
-
(1993)
Semin Cell Biol.
, vol.4
, pp. 37-44
-
-
Harris, A.1
Argent, B.E.2
-
7
-
-
0035002975
-
Multidrug transport by ATP binding cassette transporters: A proposed two-cylinder engine mechanism
-
van Veen H.W., Higgins C.F., Konings W.N. Multidrug transport by ATP binding cassette transporters: a proposed two-cylinder engine mechanism. Res. Microbiol. 152:2001;365-374.
-
(2001)
Res. Microbiol.
, vol.152
, pp. 365-374
-
-
Van Veen, H.W.1
Higgins, C.F.2
Konings, W.N.3
-
9
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
Fishel R., Lescoe M.K., Rao M.R., Copeland N.G., Jenkins N.A., Garber J., Kane M., Kolodner R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell. 75:1993;1027-1038.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.3
Copeland, N.G.4
Jenkins, N.A.5
Garber, J.6
Kane, M.7
Kolodner, R.8
-
10
-
-
0032076248
-
The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair to the cellular DNA damage response
-
Carney J.P., Maser R.S., Olivares H., Davis E.M., Le Beau M., Yates J.R. III, Hays L., Morgan W.F., Petrini J.H. The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response. Cell. 93:1998;477-486.
-
(1998)
Cell
, vol.93
, pp. 477-486
-
-
Carney, J.P.1
Maser, R.S.2
Olivares, H.3
Davis, E.M.4
Le Beau, M.5
Yates J.R. III6
Hays, L.7
Morgan, W.F.8
Petrini, J.H.9
-
11
-
-
0033544724
-
The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder
-
Stewart G.S., Maser R.S., Stankovic T., Bressan D.A., Kaplan M.I., Jaspers N.G., Raams A., Byrd P.J., Petrini J.H., Taylor A.M. The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder. Cell. 99:1999;577-587.
-
(1999)
Cell
, vol.99
, pp. 577-587
-
-
Stewart, G.S.1
Maser, R.S.2
Stankovic, T.3
Bressan, D.A.4
Kaplan, M.I.5
Jaspers, N.G.6
Raams, A.7
Byrd, P.J.8
Petrini, J.H.9
Taylor, A.M.10
-
12
-
-
0025374695
-
Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport
-
Hyde S.C., Emsley P., Hartshorn M.J., Mimmack M.M., Gileadi U., Pearce S.R., Gallagher M.P., Gill D.R., Hubbard R.E., Higgins C.F. Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport. Nature. 346:1990;362-365.
-
(1990)
Nature
, vol.346
, pp. 362-365
-
-
Hyde, S.C.1
Emsley, P.2
Hartshorn, M.J.3
Mimmack, M.M.4
Gileadi, U.5
Pearce, S.R.6
Gallagher, M.P.7
Gill, D.R.8
Hubbard, R.E.9
Higgins, C.F.10
-
13
-
-
0033610852
-
DNA-dependent activation of the hMutSalpha ATPase
-
Blackwell L.J., Bjornson K.P., Modrich P. DNA-dependent activation of the hMutSalpha ATPase. J. Biol. Chem. 273:1998;32049-32054.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32049-32054
-
-
Blackwell, L.J.1
Bjornson, K.P.2
Modrich, P.3
-
14
-
-
0033083040
-
HMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA
-
Gradia S., Subramanian D., Wilson T., Acharya S., Makhov A., Griffith J., Fishel R. hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA. Mol. Cell. 3:1999;255-261.
-
(1999)
Mol. Cell
, vol.3
, pp. 255-261
-
-
Gradia, S.1
Subramanian, D.2
Wilson, T.3
Acharya, S.4
Makhov, A.5
Griffith, J.6
Fishel, R.7
-
15
-
-
0035102126
-
Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair
-
Junop M.S., Obmolova G., Rausch K., Hsieh P., Yang W. Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair. Mol. Cell. 7:2001;1-12.
-
(2001)
Mol. Cell.
, vol.7
, pp. 1-12
-
-
Junop, M.S.1
Obmolova, G.2
Rausch, K.3
Hsieh, P.4
Yang, W.5
-
16
-
-
0036276388
-
The Mre11 complex: At the crossroads of DNA repair and checkpoint signalling
-
D'Amours D., Jackson S.P. The Mre11 complex: at the crossroads of DNA repair and checkpoint signalling. Nat. Rev. Mol. Cell. Biol. 3:2002;317-327.
-
(2002)
Nat. Rev. Mol. Cell. Biol.
, vol.3
, pp. 317-327
-
-
D'Amours, D.1
Jackson, S.P.2
-
17
-
-
0036682830
-
Tethering on the brink: The evolutionarily conserved Mre11-Rad50 complex
-
Connelly J.C., Leach D.R. Tethering on the brink: the evolutionarily conserved Mre11-Rad50 complex. Trends Biochem. Sci. 27:2002;410-418.
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 410-418
-
-
Connelly, J.C.1
Leach, D.R.2
-
18
-
-
0035806955
-
Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere
-
Diede S.J., Gottschling D.E. Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere. Curr. Biol. 11:2001;1336-1340.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1336-1340
-
-
Diede, S.J.1
Gottschling, D.E.2
-
19
-
-
0037169325
-
The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements
-
Lobachev K.S., Gordenin D.A., Resnick M.A. The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements. Cell. 108:2002;183-193.
-
(2002)
Cell
, vol.108
, pp. 183-193
-
-
Lobachev, K.S.1
Gordenin, D.A.2
Resnick, M.A.3
-
20
-
-
0035692142
-
Overlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolism
-
Moreau S., Morgan E.A., Symington L.S. Overlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolism. Genetics. 159:2001;1423-1433.
-
(2001)
Genetics
, vol.159
, pp. 1423-1433
-
-
Moreau, S.1
Morgan, E.A.2
Symington, L.S.3
-
21
-
-
0035930342
-
Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes
-
Chen L., Trujillo K., Ramos W., Sung P., Tomkinson A.E. Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes. Mol. Cell. 8:2001;1105-1115.
-
(2001)
Mol. Cell
, vol.8
, pp. 1105-1115
-
-
Chen, L.1
Trujillo, K.2
Ramos, W.3
Sung, P.4
Tomkinson, A.E.5
-
23
-
-
0033563229
-
Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex
-
Paull T.T., Gellert M. Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex. Genes Dev. 13:1999;1276-1288.
-
(1999)
Genes Dev.
, vol.13
, pp. 1276-1288
-
-
Paull, T.T.1
Gellert, M.2
-
24
-
-
0037084037
-
The ABCs of SMC proteins: Two-armed ATPases for chromosome condensation, cohesion, and repair
-
Hirano T. The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion, and repair. Genes Dev. 16:2002;399-414.
-
(2002)
Genes Dev.
, vol.16
, pp. 399-414
-
-
Hirano, T.1
-
25
-
-
0034231606
-
P-glycoprotein as a drug target in the treatment of multidrug resistant cancer
-
Lehne G. P-glycoprotein as a drug target in the treatment of multidrug resistant cancer. Curr. Drug Targets. 1:2000;85-99.
-
(2000)
Curr. Drug Targets
, vol.1
, pp. 85-99
-
-
Lehne, G.1
-
26
-
-
0032321699
-
The ABC family of multidrug transporters in microorganisms
-
van Veen H.W., Konings W.N. The ABC family of multidrug transporters in microorganisms. Biochim. Biophys. Acta. 1365:1998;31-36.
-
(1998)
Biochim. Biophys. Acta
, vol.1365
, pp. 31-36
-
-
Van Veen, H.W.1
Konings, W.N.2
-
27
-
-
0032542358
-
Crystal structure of the ATP-binding subunit of an ABC transporter
-
Hung L.W., Wang I.X., Nikaido K., Liu P.Q., Ames G.F., Kim S.H. Crystal structure of the ATP-binding subunit of an ABC transporter. Nature. 396:1998;703-707.
-
(1998)
Nature
, vol.396
, pp. 703-707
-
-
Hung, L.W.1
Wang, I.X.2
Nikaido, K.3
Liu, P.Q.4
Ames, G.F.5
Kim, S.H.6
-
28
-
-
0037052565
-
The E. coli BtuCD structure: A framework for ABC transporter architecture and mechanism
-
12 uptake in E. coli reveals the basic architectural principles of ABC transporters, including the two nucleotide-binding domain: two transmembrane domain architecture, the communication between nucleotide-binding domains and transmembrane domains, and transmembrane pore formation. The structure also shows that the ABC ATPase domain dimer architecture is preserved from ABC transporters to DNA repair enzymes.
-
12 uptake in E. coli reveals the basic architectural principles of ABC transporters, including the two nucleotide-binding domain: two transmembrane domain architecture, the communication between nucleotide-binding domains and transmembrane domains, and transmembrane pore formation. The structure also shows that the ABC ATPase domain dimer architecture is preserved from ABC transporters to DNA repair enzymes.
-
(2002)
Science
, vol.296
, pp. 1091-1098
-
-
Locher, K.P.1
Lee, A.T.2
Rees, D.C.3
-
29
-
-
0035943735
-
The crystal structure of the MJ0796 ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter
-
Yuan Y.R., Blecker S., Martsinkevich O., Millen L., Thomas P.J., Hunt J.F. The crystal structure of the MJ0796 ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter. J. Biol. Chem. 276:2001;32313-32321.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 32313-32321
-
-
Yuan, Y.R.1
Blecker, S.2
Martsinkevich, O.3
Millen, L.4
Thomas, P.J.5
Hunt, J.F.6
-
30
-
-
0035830484
-
Crystal structure of the SMC head domain: An ABC ATPase with 900 residues antiparallel coiled-coil inserted
-
The authors report the crystal structure of the ABC ATPase domain of an SMC protein. The work unified structural principles of SMC proteins with Rad50 and suggested how ABC ATPase domains are mechanistically involved in chromosome segregation and condensation processes.
-
Lowe J., Cordell S.C., van den Ent F. Crystal structure of the SMC head domain: an ABC ATPase with 900 residues antiparallel coiled-coil inserted. J. Mol. Biol. 306:2001;25-35 The authors report the crystal structure of the ABC ATPase domain of an SMC protein. The work unified structural principles of SMC proteins with Rad50 and suggested how ABC ATPase domains are mechanistically involved in chromosome segregation and condensation processes.
-
(2001)
J. Mol. Biol.
, vol.306
, pp. 25-35
-
-
Lowe, J.1
Cordell, S.C.2
Van Den Ent, F.3
-
31
-
-
0034941969
-
Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter
-
Karpowich N., Martsinkevich O., Millen L., Yuan Y.R., Dai P.L., MacVey K., Thomas P.J., Hunt J.F. Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter. Structure. 9:2001;571-586.
-
(2001)
Structure
, vol.9
, pp. 571-586
-
-
Karpowich, N.1
Martsinkevich, O.2
Millen, L.3
Yuan, Y.R.4
Dai, P.L.5
MacVey, K.6
Thomas, P.J.7
Hunt, J.F.8
-
32
-
-
0035801375
-
Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing
-
Gaudet R., Wiley D.C. Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing. EMBO J. 20:2001;4964-4972.
-
(2001)
EMBO J.
, vol.20
, pp. 4964-4972
-
-
Gaudet, R.1
Wiley, D.C.2
-
33
-
-
0035823075
-
Structure of MsbA from E. coli: A homolog of the multidrug resistance ATP binding cassette (ABC) transporters
-
The first crystal structure of a complete ABC transporter revealed fundamental insights into the architecture of ABC transporters and how ATP might drive lipid flipping and multidrug export by P-glycoprotein-related enzymes.
-
Chang G., Roth C.B. Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters. Science. 293:2001;1793-1800 The first crystal structure of a complete ABC transporter revealed fundamental insights into the architecture of ABC transporters and how ATP might drive lipid flipping and multidrug export by P-glycoprotein-related enzymes.
-
(2001)
Science
, vol.293
, pp. 1793-1800
-
-
Chang, G.1
Roth, C.B.2
-
34
-
-
0034641938
-
Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA
-
••], reports the first crystal structure of a complete ABC-type enzyme and suggests molecular mechanisms for how ATP might regulate DNA mismatch detection and binding by MutS. This is the only structure available for ABC-type enzymes bound to substrate DNA. The two ABC ATPase domains revealed a similar dimer architecture to that seen in the ATP-bound Rad50 ABC ATPase domain structure, suggesting an universally conserved principle of ABC enzyme architecture and mechanism.
-
••], reports the first crystal structure of a complete ABC-type enzyme and suggests molecular mechanisms for how ATP might regulate DNA mismatch detection and binding by MutS. This is the only structure available for ABC-type enzymes bound to substrate DNA. The two ABC ATPase domains revealed a similar dimer architecture to that seen in the ATP-bound Rad50 ABC ATPase domain structure, suggesting an universally conserved principle of ABC enzyme architecture and mechanism.
-
(2000)
Nature
, vol.407
, pp. 703-710
-
-
Obmolova, G.1
Ban, C.2
Hsieh, P.3
Yang, W.4
-
36
-
-
0034705293
-
Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily
-
This paper reports the crystal structure of the ATPase domain of Rad50, both in the absence of ATP and as an ATP complex. This first structure of an ABC ATPase domain in the biologically relevant dimeric state shows that ATP promotes the association of two Rad50 ATPase domains and defines the role of the conserved ABC signature motif. The structural results suggest a mechanism for how ATP controls conformational switching in the ABC ATPase superfamily.
-
Hopfner K.P., Karcher A., Shin D.S., Craig L., Arthur L.M., Carney J.P., Tainer J.A. Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily. Cell. 101:2000;789-800 This paper reports the crystal structure of the ATPase domain of Rad50, both in the absence of ATP and as an ATP complex. This first structure of an ABC ATPase domain in the biologically relevant dimeric state shows that ATP promotes the association of two Rad50 ATPase domains and defines the role of the conserved ABC signature motif. The structural results suggest a mechanism for how ATP controls conformational switching in the ABC ATPase superfamily.
-
(2000)
Cell
, vol.101
, pp. 789-800
-
-
Hopfner, K.P.1
Karcher, A.2
Shin, D.S.3
Craig, L.4
Arthur, L.M.5
Carney, J.P.6
Tainer, J.A.7
-
37
-
-
0034669176
-
Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis
-
Diederichs K., Diez J., Greller G., Muller C., Breed J., Schnell C., Vonrhein C., Boos W., Welte W. Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis. EMBO J. 19:2000;5951-5961.
-
(2000)
EMBO J.
, vol.19
, pp. 5951-5961
-
-
Diederichs, K.1
Diez, J.2
Greller, G.3
Muller, C.4
Breed, J.5
Schnell, C.6
Vonrhein, C.7
Boos, W.8
Welte, W.9
-
38
-
-
0032821236
-
Subunit interactions in ABC transporters: Towards a functional architecture
-
Jones P.M., George A.M. Subunit interactions in ABC transporters: towards a functional architecture. FEMS Microbiol. Lett. 179:1999;187-202.
-
(1999)
FEMS Microbiol. Lett.
, vol.179
, pp. 187-202
-
-
Jones, P.M.1
George, A.M.2
-
39
-
-
0033603452
-
Modulation of ATPase activity by physical disengagement of the ATP-binding domains of an ABC transporter, the histidine permease
-
Liu P.Q., Liu C.E., Ames G.F. Modulation of ATPase activity by physical disengagement of the ATP-binding domains of an ABC transporter, the histidine permease. J. Biol. Chem. 274:1999;18310-18318.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18310-18318
-
-
Liu, P.Q.1
Liu, C.E.2
Ames, G.F.3
-
40
-
-
0034212332
-
The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism
-
van Veen H.W., Margolles A., Muller M., Higgins C.F., Konings W.N. The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism. EMBO J. 19:2000;2503-2514.
-
(2000)
EMBO J.
, vol.19
, pp. 2503-2514
-
-
Van Veen, H.W.1
Margolles, A.2
Muller, M.3
Higgins, C.F.4
Konings, W.N.5
-
41
-
-
0037162468
-
Vanadate-catalyzed photocleavage of the signature motif of an ATP- binding cassette (ABC) transporter
-
Fetsch E.E., Davidson A.L. Vanadate-catalyzed photocleavage of the signature motif of an ATP- binding cassette (ABC) transporter. Proc. Natl. Acad. Sci. USA. 99:2002;9685-9690.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9685-9690
-
-
Fetsch, E.E.1
Davidson, A.L.2
-
42
-
-
0037077296
-
Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters
-
Moody J.E., Millen L., Binns D., Hunt J.F., Thomas P.J. Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters. J. Biol. Chem. 277:2002;21111-21114.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21111-21114
-
-
Moody, J.E.1
Millen, L.2
Binns, D.3
Hunt, J.F.4
Thomas, P.J.5
-
43
-
-
0034483133
-
DNA mismatch repair: The hands of a genome guardian
-
Hopfner K.P., Tainer J.A. DNA mismatch repair: the hands of a genome guardian. Structure. 8:2000;R237-R241.
-
(2000)
Structure
, vol.8
-
-
Hopfner, K.P.1
Tainer, J.A.2
-
44
-
-
0036342413
-
ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer
-
The first crystal structure of the ABC ATPase domain of an ABC transporter in the biologically relevant dimeric form revealed how ATP induces conformational changes in the nucleotide-binding domain of the transporter and showed that the basic mechanism of ABC ATPase domains in ABC transporters and DNA repair enzymes is remarkably conserved. To obtain crystals of this form, the authors introduced an active site mutation that permitted ATP binding, but prevented ATP hydrolysis.
-
Smith P.C., Karpowich N., Millen L., Moody J.E., Rosen J., Thomas P.J., Hunt J.F. ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer. Mol. Cell. 10:2002;139-149 The first crystal structure of the ABC ATPase domain of an ABC transporter in the biologically relevant dimeric form revealed how ATP induces conformational changes in the nucleotide-binding domain of the transporter and showed that the basic mechanism of ABC ATPase domains in ABC transporters and DNA repair enzymes is remarkably conserved. To obtain crystals of this form, the authors introduced an active site mutation that permitted ATP binding, but prevented ATP hydrolysis.
-
(2002)
Mol. Cell.
, vol.10
, pp. 139-149
-
-
Smith, P.C.1
Karpowich, N.2
Millen, L.3
Moody, J.E.4
Rosen, J.5
Thomas, P.J.6
Hunt, J.F.7
-
45
-
-
0033485380
-
Functional consequences of mutations in the conserved 'signature sequence' of the ATP-binding-cassette protein MalK
-
Schmees G., Stein A., Hunke S., Landmesser H., Schneider E. Functional consequences of mutations in the conserved 'signature sequence' of the ATP-binding-cassette protein MalK. Eur. J. Biochem. 266:1999;420-430.
-
(1999)
Eur. J. Biochem.
, vol.266
, pp. 420-430
-
-
Schmees, G.1
Stein, A.2
Hunke, S.3
Landmesser, H.4
Schneider, E.5
-
46
-
-
0035906860
-
Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase
-
Hopfner K.P., Karcher A., Craig L., Woo T.T., Carney J.P., Tainer J.A. Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase. Cell. 105:2001;473-485.
-
(2001)
Cell
, vol.105
, pp. 473-485
-
-
Hopfner, K.P.1
Karcher, A.2
Craig, L.3
Woo, T.T.4
Carney, J.P.5
Tainer, J.A.6
-
48
-
-
0035957431
-
Allosteric crosstalk between peptide-binding, transport, and ATP hydrolysis of the ABC transporter TAP
-
Gorbulev S., Abele R., Tampe R. Allosteric crosstalk between peptide-binding, transport, and ATP hydrolysis of the ABC transporter TAP. Proc. Natl. Acad. Sci. USA. 98:2001;3732-3737.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3732-3737
-
-
Gorbulev, S.1
Abele, R.2
Tampe, R.3
-
49
-
-
0036792404
-
The many functions of SMC proteins in chromosome dynamics
-
Jessberger R. The many functions of SMC proteins in chromosome dynamics. Nat. Rev. Mol. Cell. Biol. 3:2002;767-778.
-
(2002)
Nat. Rev. Mol. Cell. Biol.
, vol.3
, pp. 767-778
-
-
Jessberger, R.1
-
50
-
-
0037046871
-
Chromosome organization: Reaching out to embrace new models
-
Wyman C., Kanaar R. Chromosome organization: reaching out to embrace new models. Curr. Biol. 12:2002;R446-R448.
-
(2002)
Curr. Biol.
, vol.12
-
-
Wyman, C.1
Kanaar, R.2
-
51
-
-
0036682314
-
The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair
-
•]) or intermolecularly linked coiled-coil structures that are suitable for bridging sister chromatids in homologous recombination.
-
•]) or intermolecularly linked coiled-coil structures that are suitable for bridging sister chromatids in homologous recombination.
-
(2002)
Nature
, vol.418
, pp. 562-566
-
-
Hopfner, K.P.1
Craig, L.2
Moncalian, G.3
Zinkel, R.A.4
Usui, T.5
Owen, B.A.6
Karcher, A.7
Henderson, B.8
Bodmer, J.L.9
McMurray, C.T.10
-
52
-
-
0036242551
-
Molecular architecture of SMC proteins and the yeast cohesin complex
-
Structural and biochemical experiments reveal the basic molecular architecture and hinge-mediated association of SMC protein homodimers and heterodimers. The authors propose the 'clasping' model of sister chromatid cohesion, in which an SMC dimer forms a ring around two sister chromatids.
-
Haering C.H., Lowe J., Hochwagen A., Nasmyth K. Molecular architecture of SMC proteins and the yeast cohesin complex. Mol. Cell. 9:2002;773-788 Structural and biochemical experiments reveal the basic molecular architecture and hinge-mediated association of SMC protein homodimers and heterodimers. The authors propose the 'clasping' model of sister chromatid cohesion, in which an SMC dimer forms a ring around two sister chromatids.
-
(2002)
Mol. Cell.
, vol.9
, pp. 773-788
-
-
Haering, C.H.1
Lowe, J.2
Hochwagen, A.3
Nasmyth, K.4
-
53
-
-
0035930329
-
Human Rad50/Mre11 is a flexible complex that can tether DNA ends
-
Atomic force microscopy data on the human Mre11-Rad50 complex in the presence of DNA revealed that the coiled coil of the Rad50 ABC ATPase is a highly dynamic structure that can dynamically form tethers or loops in linking DNA ends or sister chromatids as one of the fundamental initial steps in DNA double-strand break repair.
-
de Jager M., van Noort J., van Gent D.C., Dekker C., Kanaar R., Wyman C. Human Rad50/Mre11 is a flexible complex that can tether DNA ends. Mol. Cell. 8:2001;1129-1135 Atomic force microscopy data on the human Mre11-Rad50 complex in the presence of DNA revealed that the coiled coil of the Rad50 ABC ATPase is a highly dynamic structure that can dynamically form tethers or loops in linking DNA ends or sister chromatids as one of the fundamental initial steps in DNA double-strand break repair.
-
(2001)
Mol. Cell.
, vol.8
, pp. 1129-1135
-
-
De Jager, M.1
Van Noort, J.2
Van Gent, D.C.3
Dekker, C.4
Kanaar, R.5
Wyman, C.6
-
54
-
-
0035813227
-
Structure of the Rad50×Mre11 DNA repair complex from Saccharomyces cerevisiae by electron microscopy
-
Anderson D.E., Trujillo K.M., Sung P., Erickson H.P. Structure of the. Rad50×Mre11 DNA repair complex from Saccharomyces cerevisiae by electron microscopy J. Biol. Chem. 276:2001;37027-37033.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37027-37033
-
-
Anderson, D.E.1
Trujillo, K.M.2
Sung, P.3
Erickson, H.P.4
-
55
-
-
0036297532
-
Efficient supercoiling of DNA by a single condensin complex as revealed by electron spectroscopic imaging
-
Bazett-Jones D.P., Kimura K., Hirano T. Efficient supercoiling of DNA by a single condensin complex as revealed by electron spectroscopic imaging. Mol. Cell. 9:2002;1183-1190.
-
(2002)
Mol. Cell.
, vol.9
, pp. 1183-1190
-
-
Bazett-Jones, D.P.1
Kimura, K.2
Hirano, T.3
|