Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids

PLoS ONE

Volumn 5, Issue 10, 2010, Pages

  Presman, Diego M ^a,c   Alvarez, Lautaro D ^a   Levi, Valeria ^a   Eduardo, Silvina ^a   Digman, Michelle A ^b   Martí, Marcelo A ^a   Veleiro, Adriana S ^a   Burton, Gerardo ^a   Pecci, Adali ^a,c  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INSTITUTO DE FISIOLOGÍA   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

21 HEMISUCCINATE 6,19 EPOXYPROGESTERONE; 21 HYDROXY 6,19 EPOXYPROGESTERONE; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ANTAGONIST; MIFEPRISTONE; NUCLEAR RECEPTOR COACTIVATOR 2; UNCLASSIFIED DRUG; DNA; STEROID;

ARTICLE; BINDING AFFINITY; CELL ASSAY; CELL CULTURE; CELL STRAIN BHK; CELL STRAIN COS7; CELL STRAIN L 929; CELL TYPE; COMPUTER MODEL; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISSOCIATION; DNA DRUG COMPLEX; DRUG MECHANISM; DRUG RECEPTOR BINDING; GENETIC TRANSFECTION; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; LIGAND BINDING; MODULATION; MOLECULAR DYNAMICS; OLIGOMERIZATION; PROTEIN DNA BINDING; PROTEIN DNA INTERACTION; PROTEIN FUNCTION; STEROID BINDING; STRUCTURE ACTIVITY RELATION; ANIMAL; CELL LINE; CELL STRAIN COS1; CERCOPITHECUS; CHEMICAL STRUCTURE; DIMERIZATION; GEL MOBILITY SHIFT ASSAY; IMMUNOPRECIPITATION; METABOLISM; PROTEIN BINDING;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; DIMERIZATION; DNA; ELECTROPHORETIC MOBILITY SHIFT ASSAY; IMMUNOPRECIPITATION; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; RECEPTORS, GLUCOCORTICOID; STEROIDS;

EID: 78149443388     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013279     Document Type: Article

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